Protein kinase C: Molecular and cellular targets for the action of ethanol

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 8 SUPPL., 1996, Pages

  Pandey, Subhash C ^a   Alling, Christer ^b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; ANESTHETIC AGENT; DIACYLGLYCEROL; GLUTAMATE RECEPTOR; ISOENZYME; MUSCARINIC RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL DIBUTYRATE; PHOSPHOLIPASE C; PROTEIN KINASE C;

ADAPTATION; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; CONFERENCE PAPER; HUMAN; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER;

EID: 0029808496     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01749.x     Document Type: Conference Paper

References (17)

1. Cockcroft S, Thomas GMH: Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem J 288:1-14, 1992
2. Nishizuka Y: Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614, 1992
3. A receptor/chloride channel complex, in Deitrich RA (ed): Pharmacological Effects of Ethanol on the Nervous System. Boca Raton, FL, CRC Press, 1995, pp 51-72
4. Harris RA, McQuilkin SJ, Paylor R, Abeliovich A, Tonegawa S, Wehner JM: Mutant mice lacking the γ isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of transcription and the molecular mechanism of the regulation of γ-amino butyrate type A receptors. Proc Natl Acad Sci USA 92:3658-3662, 1996
5. 1 G protein-linked receptors in Xenopus oocytes expressing brain mRNA: Role of protein kinase C. Mol Pharmacol 45:1004-1012, 1994
6. Larsson C, Simonsson P, Hoek JB, Alling C: Ethanol inhibits the peak of muscarinic receptor-stimulated formation of inositol 1,4,5-trisphosphate in neuroblastoma SH-SY5Y cells. Biochem Pharmacol 50:647-654, 1995
7. Messing RO, Carpenter CL, Greenberg DA: Ethanol regulates calcium channels in clonal neural cells. Proc. Natl Acad Sci USA 83:6213-6215, 1986
8. Messing RO, Sneade AB, Savidge B: Protein kinase C participates in upregulation of dihydropyridine-sensitive calcium channels by ethanol. J Neurochem 55:1383-1389, 1990
9. Messing RO, Petersen PJ, Henrich CJ: Chronic ethanol exposure increases levels of protein kinase C-δ and -ε and protein kinase C-mediated phosphorylation in cultured neural cells. J Biol Chem 266:23428-23432, 1991
10. Hundle B. McMahon T, Dadger J, Messing RO: Overexpression of ε-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth. J Biol Chem 270:30134-30140, 1995
11. /11 subunit and phospholipase C isozymes in the rat brain. J Neurochem, 1996 (in press)
12. DePetrillo PB: Effects of chronic alcohol use and age on human lymphocyte protein kinase C activity. Pharmacol Biochem Behav 48:999-1004, 1994
13. Battaini F, Vesco RD, Govoni S: Chronic alcohol intake modifies phorbol ester binding in selected rat brain areas. Alcohol 6:169-172, 1989
14. Pandey SC, Dwivedi Y, Piano MR, Schwertz, DW, Davis JM, Pandey GN: Chronic ethanol consumption decreases the phorbol ester biding to membranal but not cytosolic protein kinase C in rat brain. Alcohol 10:259-262, 1993
15. Slater SJ, Cox KJV, Lombardi JV, Ho C, Kelly MB, Rubin E, Stubbs CD: Inhibition of protein kinase C by alcohols and anesthetics. Nature 364:82-84, 1993
16. Slater SJ, Ho C, Kelly MB, Larkin JD, Taddeo FJ, Yeager MD, Stubbs CD: Protein kinase Ca contains two activator sites that bind phorbol ester and diacylglycerols with its opposite affinities. J Biol Chem 271:4627-4631, 1996
17. Slater SJ, Kelly MB, Taddeo FJ, Rubin E, Stubbs CD: Evidence for discrete diacylglycerol and phorbol ester binding sites on protein kinase. J Biol Chem 269:17160-17165, 1994