Synthesis and properties of 3-(2-hydroxyethyl)-3-n-pentyldiazirine, a photoactivable general anesthetic

Journal of Medicinal Chemistry

Volumn 42, Issue 17, 1999, Pages 3300-3307

  Husain, S Shaukat ^a,b   Forman, Stuart A ^a,b   Kloczewiak, Marek A ^a,b   Addona, George H ^a,b   Olsen, Richard W ^c   Pratt, Megan B ^b   Cohen, Jonathan B ^b   Miller, Keith W ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 HYDROXYETHYL) 3 N PENTYLDIAZIRINE; 4 AMINOBUTYRIC ACID A RECEPTOR; ANESTHETIC AGENT; CHOLINERGIC RECEPTOR; NICOTINIC RECEPTOR; OCTANOL; POSTSYNAPTIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL REACTION; DRUG BINDING SITE; DRUG EFFECT; DRUG INHIBITION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GABAERGIC TRANSMISSION; NONHUMAN; TADPOLE;

ALLOSTERIC REGULATION; ANESTHETICS, GENERAL; ANIMALS; AZIRINES; CATTLE; CELL MEMBRANE; CEREBRAL CORTEX; ELECTRIC ORGAN; HUMANS; LARVA; LIGANDS; MICE; OCTANOLS; OOCYTES; PATCH-CLAMP TECHNIQUES; RANA PIPIENS; RECEPTORS, GABA-A; RECEPTORS, NICOTINIC; TORPEDO; ULTRAVIOLET RAYS; XENOPUS;

EID: 0033606987     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9806300     Document Type: Article

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