MapsiDB: An integrated web database for type i polyketide synthases

Bioprocess and Biosystems Engineering

Volumn 32, Issue 6, 2009, Pages 723-727

  Tae, Hongseok ^a   Sohng, Jae Kyung ^b   Park, Kiejung ^a  

^a SmallSoft Co Ltd   (South Korea)

^b SunMoon University   (South Korea)

Author keywords

MAPSI; MapsiDB; PKS; PKSDB; Polyketide

Indexed keywords

MAPSI; MAPSIDB; PKS; PKSDB; POLYKETIDE;

CARBOXYLIC ACIDS; ENZYMES; ORGANIC ACIDS;

DATABASE SYSTEMS;

POLYKETIDE;

ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; GENE SEQUENCE; GENOME; PRIORITY JOURNAL;

DATABASE MANAGEMENT SYSTEMS; DATABASES, GENETIC; DATABASES, PROTEIN; INTERNET; MACROLIDES; POLYKETIDE SYNTHASES; USER-COMPUTER INTERFACE;

EID: 69249223048     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-008-0296-3     Document Type: Article

References (27)

1. B Silakowski HU Schairer H Ehret B Kunze S Weinig G Nordsiek P Brandt H Blöcker G Höfle S Beyer R Müller 1999 New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1 J Biol Chem 274 37391 37399
2. SJ Kakavas L Katz D Stassi 1997 Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis J Bacteriol 179 7515 7522
3. H Ikeda T Nonomiya M Usami T Ohta S Omura 1999 Organization of the biosynthetic gene cluster for the polyketide antihelmintic macrolide avermectin in Streptomyces avermitilis Proc Natl Acad Sci USA 96 9509 9514
4. S Omura H Ikeda J Ishikawa A Hanamoto C Takahashi M Shinose Y Takahashi H Horikawa H Nakazawa T Osonoe H Kikuchi T Shiba Y Sakaki M Hattori 2001 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites Proc Nat Acad Sci USA 98 12215 12220
5. JF Aparicio P Caffrey AFA Marsden J Staunton PF Leadlay 1994 Limited proteolysis and active-site studies of the first multienzyme component of the erythromycin-producing polyketide synthase J Biol Chem 269 8524 8528
6. HG Floss TW Yu 1999 Lessons from the rifamycin biosynthetic gene cluster Curr Opin Chem Biol 3 592 597
7. YQ Cheng GL Tang B Shen 2003 Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis Proc Natl Acad Sci USA 100 3149 3154 (Pubitemid 36356554)
8. BJ Rawlings 2001 Type I polyketide biosynthesis in bacteria (part A-erythromycin biosynthesis) Nat Prod Rep 18 190 227
9. BJ Rawlings 2001 Type I polyketide biosynthesis in bacteria (part B) Nat Prod Rep 18 231 281
10. J Staunton KJ Weissman 2001 Polyketide biosynthesis: a millennium review Nat Prod Rep 18 380 416
11. DE Cane 1997 Introduction: polyketide and nonribosomal polypeptide biosynthesis Chem Rev 97 2463 2706
12. N Funa Y Ohnishi I Fujii M Shibuya Y Ebizuka S Horinouchi 1999 A new pathway for polyketide synthesis in microorganisms Nature 400 897 899
13. BS Moore JN Hopke 2001 Discovery of a new bacterial polyketide biosynthetic pathway ChemBioChem 2 35 38
14. KE Wiesmann J Cortes MJ Brown AL Cutter J Staunton PF Leadlay 1995 Polyketide synthesis in vitro on a modular polyketide synthase Chem Biol 2 583 589
15. M Gaitatzis B Silakowski B Kunze G Nordsiek H Blöcker G Höfle R Müller 2002 The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase J Biol Chem 277 13082 13090
16. B Shen CR Hutchinson 1996 Deciphering the mechanism for the assembly of aromatic polyketides by a bacterial polyketide synthase Proc Natl Acad Sci USA 93 6600 6604
17. G Yadav RS Gokhale D Mohanty 2003 Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases J Mol Biol 328 335 363
18. MZ Ansari G Yadav RS Gokhale D Mohanty 2004 NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases Nucleic Acids Res 32 W405 W413
19. MAPSI. http://gate.smallsoft.co.kr:8080/pks
20. R McDaniel A Thamchaipenet C Gustafsson H Fu M Betlach M Betlach G Ashley 1999 Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products Proc Natl Acad Sci USA 96 1846 1851
21. R McDaniel CM Kao SJ Hwang C Khosla 1997 Engineered intermodular and intramodular polyketide synthase fusions Chem Biol 4 667 674
22. SR Eddy 1998 Profile hidden Markov models Bioinformatics 14 755 763
23. CM Ronning ND Fedorova P Bowyer R Coulson G Goldman HS Kim G Turner JR Wortman J Yu MJ Anderson DW Denning WC Nierman 2005 Genomics of Aspergillus fumigatus Rev Iberoam Micol 22 4 223 228
24. JE Galagan SE Calvo C Cuomo LJ Ma JR Wortman, et al. 2005 Sequencing of Aspergillus nidulans and comparative analysis with A. fumitatus and A. oryzae Nature 438 1105 1115
25. SF Altschul W Gish W Miller EW Myers DJ Lipman 1990 Basic local alignment search tool J Mol Biol 215 403 410
26. JD Thompson DG Higgins TJ Gibson 1994 CLUSTALW: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Nucleic Acids Res 22 4673 4680
27. NCBI. http://www.ncbi.nlm.nih.gov