Expression of type 2 11β-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in early human fetal life

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 12, 1998, Pages 4490-4497

  Condon, Jennifer ^a   Gosden, Christine ^b   Gardener, Derek ^b   Nickson, Paul ^b   Hewison, Martin ^a   Howie, Alexander J ^a   Stewart, Paul M ^a,c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTEROID; CORTICOSTEROID RECEPTOR; CORTISONE; GLUCOCORTICOID; HYDROCORTISONE; MINERALOCORTICOID RECEPTOR;

ADRENAL MEDULLA; ARTICLE; BONE DEVELOPMENT; ENZYME LOCALIZATION; ENZYME REGULATION; FETUS; FETUS DEVELOPMENT; FETUS GROWTH; FETUS LUNG MATURATION; GESTATION PERIOD; GESTATIONAL AGE; GONAD DEVELOPMENT; HORMONAL REGULATION; HUMAN; HUMAN TISSUE; KIDNEY DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SODIUM BALANCE; TISSUE DIFFERENTIATION;

EID: 0032452922     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.83.12.5302     Document Type: Article

References (50)

1. 1. Funder JW. 1987 Adrenal steroids: new answers, new questions. Science. 237:236-237.
2. 2. Munck A, Mendel DB, Smith LI, Orti E. 1990 Glucocorticoid receptors and actions. Am Rev Respir Dis. 141:S2-S10.
3. 3. Krozowski ZS, Funder JW. 1983 Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity. Proc Natl Acad Sci USA. 80:6056-6060.
4. 4. Arriza JL, Weinberger C, Cerelli G, et al. 1988 Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor. Science. 237:268-275.
5. 5. Edwards CRW, Stewart PM, Burt D, et al. 1988 Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet. 2:986-989.
6. 6. Funder JW, Pearce PT, Smith R, Smith AI. 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science. 242:583-585.
7. 7. White PC, Mune T, Agarawl AK. 1997 11β-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr Rev. 18:135-156.
8. 8. Stewart PM, Wallace AM, Valentino R, Burt D, Shackleton CHL, Edwards CRW. 1987 Mineralocorticoid activity of liquorice: 11β-hydroxysteroid dehydrogenase deficiency comes of age. Lancet. 2:821-824.
9. 9. Murphy BEP. 1981 Ontogeny of cortisol-cortisone interconversion in human tissues: a role of cortisone in human fetal development. J Steroid Biochem. 14:811-817.
10. 10. Brown RW, Chapman KE, Edwards CRW, Seckl JR. 1993 Human placental 11β-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology. 132:2614-2621.
11. 11. Stewart PM, Murry BA, Mason JI. 1994 Type 2 11β-hydroxysteroid dehydrogenase in human fetal tissues. J Clin Endocrinol Metab. 78:1529-1532.
12. 12. Edwards CRW, Benediktsson R, Lindsay RS, Seckl JR. 1993 Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension? Lancet. 341:355-357.
13. 13. Barker DJP, Osmond C, Simmonds S. 1990 Fetal and placental size and risk of hypertension in adult life. Br Med J. 301:259-262.
14. 14. Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CRW. 1993 Glucocorticoid exposure in utero: new model for adult hypertension. Lancet. 341:339-341.
15. 15. Cole TJ, Blendy JA, Monaghan P, et al. 1995 Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin development and severely retards lung maturation. Genes Dev. 9:1608-1621.
16. 16. Polkinghorne Report. 1989 Review of the guidance on the research use of fetuses and fetal material. Her Majesty's Stationery Office: London.
17. 17. Dylevsky I. 1969 Relation between the length of long limb bones, outer dimensions of limbs and the crown-rump length in embryos and fetuses. Folia Morphol. 17:147-157.
18. 18. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. 1994 Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol. 105:R11-R17.
19. 19. Hollenberg SM, Weinberger C, Ong ES, et al. 1985 Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature. 318:635-641.
20. 20. Durrant I. 1996 Nonradioactive in situ hybridization for cells and tissues. Methods Mol Biol. 58:155-167.
21. 21. Shimojo M, Ricketts ML, Petrelli MD, et al. 1997 Immunodetection of 11β-hydroxysteroid dehydrogenase type 2 in human mineralocorticoid target tissues: evidence for nuclear localization. Endocrinology. 138:1305-1311.
22. 22. Stewart PM. 1996 11β-hydroxysteroid dehydrogenase: implications for clinical medicine. Clin Endocrinol (Oxf). 44:493-499.
23. 23. Jamieson PM, Chapman KE, Edwards CRW, Seckl JR. 1995 11β-Hydroxysteroid dehydrogenase is an exclusive 11β-reductase in primary cultures of rat hepatocytes: effects of physiochemical and hormonal manipulations. Endocrinology. 136:4754-4761.
24. 24. Whorwood CB, Sheppard MC, Stewart PM. 1993 Licorice inhibits 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and potentiates glucocorticoid hormone action. Endocrinology. 132:2287-2292.
25. 25. Stewart PM, Murry BA, Mason JI. 1994 Human kidney 11β-hydroxysteroid dehydrogenase is a high affinity NAD ' -dependent enzyme and differs from the cloned "type I" isoform. J Clin Endocrinol Metab. 79:480-484.
26. 26. Bro-Rasmussen F, Buus O, Trolle D. 1962 Ratio of cortisone/cortisol in mother and infant at birth. Acta Endocrinol (Copenh). 40:579-583.
27. 27. Shams M, Kilby MD, Somerset DA, et al. 1998 Ontogeny of placental 11β-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth retardation. Hum Reprod. 13:799-804.
28. 28. Howard E, Granoff DM. 1968 Increased voluntary running and decreased motor co-ordination in mice after neonatal corticosterone implantation. Exp Neurol. 22:661-673.
29. 29. Cotterrell M, Blazs R, Johnson A. 1972 Effects of corticosteroids on the biochemical maturation of rat brain postnatal cell formation. J Neurochem. 19:2151-2167.
30. 30. Bongiovanni AM, McPadden AJ. 1960 Steroids during pregnancy and possible fetal consequences. Fertil Steril. 11:181-186.
31. 31. Reinisch JM, Simon NG, Karow WG, Gandelman R. 1978 Prenatal exposure to prednisone in humans and animals retards intrauterine growth. Science. 202:436-438.
32. 32. Lindsay RS, Lindsay RM, Edwards CRW, Seckl JR. 1996 Inhibition of 11β-hydroxysteroid dehydrogenase in pregnant rats and the porgramming of blood pressure in the offspring. Hypertension. 27:1200-1204.
33. 33. Condon J, Bujalska I, Stewart FM. 1997 Inhibition of maternal and fetal 11β-hydroxysteroid dehydrogenase type 2 across gestation does not alter birth or placental weight in the mouse. J Endocrinol. 152S:P57.
34. 34. Stewart PM, Rogerson FM, Mason JI. 1995 Type 2 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis. J Clin Endocrinol Metab. 80:885-890.
35. 35. Rogerson FM, Kayes MK, White PC. 1997 Variation in placental type 2 11β-hydroxysteroid dehydrogenase activity is not related to birth or placental weight. Mol Cell Endocrinol. 128:103-109.
36. 36. Abramovich DR, Heaton B, Page KR. 1974 Transfer of labelled urea, creatinine and electrolytes between liquor amnii and the fetoplacental unit in mid pregnancy. Eur J Gynaecol Reprod Biol. 4:143-147.
37. 37. Paavonen K, Horellikuitunen N, Chilov B, et al. 1996 Novel human vascular endothelial growth-factor genes VEGF-B and VEGF-C localize to chromosomes 11Q13 and 4Q34 respectively. Circulation. 93:1079-1082.
38. 38. Kitamolo Y, Tokunaga H, Tomita K. 1997 Vascular endothelial growth factor is an essential molecule for mouse kidney development: glomerulogenesis and nephrogenesis. J Clin Invest. 99:2351-2357.
39. 39. Heiss JD, Papavassiliou E, Merrill MJ, et al. 1997 Mechanism of dexamethasone suppression of brain tumor-associated vascular permeabilty in rats. Involvment of the glucocorticoid receptor and vascular permeability factor. J Clin Invest. 98:1400-1408.
40. 40. Muglia L, Jacobsen L, Dikkes P, Majzoub JA. 1995 Corticotrophin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature. 373:427-432.
41. 41. Haagsman HP, Golde LM. 1991 Synthesis and assembly of lung surfactant. Annu Rev Physiol. 53:441-464.
42. 42. Mendelson CR, Boggaram V. 1991 Hormonal control of the surfactant system in fetal lung. Annu Rev Physiol. 53:415-440.
43. 43. Champigny G, Voilley N, Lingueglia E, Friend V, Barbry P, Lazdunski M. 1994 Regulation of the lung amiloride-sensitive Na ' channel by steroid hormones. EMBO J. 13:2177-2181.
44. 44. Crowder RE. 1957 The development of the adrenal gland in man with special reference to origin and ultimate location of cell types and evidence in favour of the cell migration theory. Contrib Embryol. 36:195-210.
45. 45. Doody KM, Carr BR, Rainey WE, et al. 1990 3β-Hydroxysteroid dehydrogenase/isomerase in the fetal zone and neocortex of the human fetal adrenal gland. Endocrinology. 126:2487-2492.
46. 46. Sippel WG, Dorr HG, Becker H, Bidlingmaier F, Mickan H, Holzmann K. 1979 Simultaneous determination of seven unconjugated steroids in maternal venous and umbilical arterial and venous serum in elective and emergeny cesarean section at term. Am J Obstet Gynecol. 135:530-542.
47. 47. Miller WL. 1988 Molecular biology of steroid hormone synthesis. Endo Rev. 9:295-318.
48. 48. Jiang W, Uht R, Bohn MC. 1989 Regulation of phenylethanolamine N-methyltransferase (PNMT) mRNA in the rat adrenal medulla by corticosterone. Int J Dev Neurosci. 7:513-520.
49. 49. Peck WA. 1984 The effects of glucocorticoids on bone cell metabolism and function. Adv Exp Med Biol. 171:111-119.
50. 50. Eyre LJ, Bland R, Hughes SV, Stewart PM, Sheppard MC, Hewison M. 11β-Hydroxysteroid dehydrogenase activity is associated with glucocorticoid receptor-mediated effects on osteoblast activity [Abstract]. J Endocrinol. In press.