Synthesis and anti-inflammatory evaluation of 9-phenoxyacridine and 4-phenoxyfuro[2,3-b]quinoline derivatives. Part 2

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 18, 2003, Pages 3921-3927

  Chen, Yeh Long ^a   Chen, I Li ^a   Lu, Chih Ming ^a   Tzeng, Cherng Chyi ^a   Tsao, Lo Ti ^b   Wang, Jih Pyang ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 CHLOROACRIDIN 9 YLOXY)BENZALDEHYDE; 4 (2 METHOXYACRIDIN 9 YLOXY)BENZALDEHYDE; 4 (4 METHOXYACRIDIN 9 YLOXY)BENZALDEHYDE; 4 (6 CHLORO 2 METHOXYACRIDIN 9 YLOXY)BENZALDEHYDE; 4 PHENOXYFURO[2,3 B]QUINOLINE; 4 [4 (2 METHOXYACRIDIN 9 YLOXY)PHENYL]BUT 3 EN 2 ONE; 4 [4 (4 METHOXYACRIDIN 9 YLOXY)PHENYL]BUT 3 EN 2 ONE; 9 PHENOXYACRIDINE; ACRIDINE DERIVATIVE; ANTIINFLAMMATORY AGENT; ARGON; BENZALDEHYDE DERIVATIVE; BETA GLUCURONIDASE; HYDROXYL GROUP; KETONE DERIVATIVE; LYSOSOME ENZYME; MEPACRINE; QUINOLINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN NERVE CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGRANULATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME RELEASE; IC 50; MACROPHAGE; MAST CELL; NEUTROPHIL; NONHUMAN; PERITONEUM CELL; RAT;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0041589305     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00439-5     Document Type: Article

References (24)

1. Menninger H., Putzier R., Mohr W., Weissinghage D., Tillmann K. J. Rheumatol. 39:1980;145.
2. Hyers T.M., Fowler A.A. Fed. Proc. Fed. Am. Soc. Exp. Biol. 45:1986;25.
3. Solbach W., Moll H., Rollinghoff M. Immunol. Today. 12:1991;4.
4. Beutler G., Cerami A. A. Annu. Rev. Biochem. 57:1988;505.
5. Wakelin L.P.G., Adams A., Denny W.A. J. Med. Chem. 45:2002;894.
6. Bailly C., Denny W.A., Mellor L.E., Wakelin L.P.G., Waring M.J. Biochemistry. 31:1992;3514.
7. Gamage S.A., Tepsiri N., Wilairat P., Wojcik S.J., Figgitt D.P., Ralph R.K., Denny W.A. J. Med. Chem. 37:1994;1486.
8. McConnaughie A.W., Jenkins T.C. J. Med. Chem. 38:1995;3488.
9. Gamage S.A., Figgitt D.F., Wojcik S.J., Ralph R.K., Ransijn A., Mauel J., Yardley V., Snowdon D., Croft S.L., Denny W.A. J. Med. Chem. 40:1997;2634.
10. Amellal M., Landry Y. Br. J. Pharmacol. 80:1983;365.
11. Chakravarty N., Nielsen E.H. Agents Actions. 18:1986;65.
12. Yu N., Maciejewski-Lenoir D., Bloom F.E., Magistretti P.J. Mol. Pharmacol. 48:1995;550.
13. Romanelli F., Fillo S., Isidori A., Conte D. Life Sci. 61:1997;557.
14. Denny W.A., Cain B.F., Hansch G.J., Panthananickal A., Leo A. J. Med. Chem. 25:1982;276.
15. Atwell G.J., Cain B.F., Seelye R.N. J. Med. Chem. 15:1972;611.
16. Zwelling L.A., Michaels S., Erickson L.C., Ungerleider R.S., Nichols M., Kohn K.W. Biochemistry. 20:1981;6553.
17. Bonse S., Santelli-Rouvier C., Barbe J., Krauth-Siegel R.L. J. Med. Chem. 42:1999;5448.
18. Chen Y.-L., Lu C.-M., Chen I.-L., Tsao L.-T., Wang J.-P. J. Med. Chem. 45:2002;4689.
19. Zhao W., Wolfender J.L., Hostettmann K., Xu R., Qin G. Phytochemistry. 47:1998;7.
20. Chen I.S., Wu Y.C., Lin I.L., Seki H., Ko F.N., Teng C.M. Phytochemistry. 36:1994;237.
21. Su T.-L., Chen C.-H., Huang L.-F., Chen C.-H., Basu M.K., Zhang X.-G., Chou T.-C. J. Med. Chem. 42:1999;4741.
22. Tuppy H., Bohm F. Monatsh. Chem. 87:1956;720.
23. Merrill J.E., Benveniste E.N. Trends Neurosci. 19:1996;331.
24. Monks A., Scuderio D., Skehan P., Shoemaker R., Paull K., Vistica D., Hose C., Langlay J., Cronise P., Vaigro-Wolff A. J. Natl. Cancer Inst. 83:1991;757.