Anti-fibrotic effects of a methylenedioxybenzene compound, CW209292 on dimethylnitrosamine-induced hepatic fibrosis in rats

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 8, 2009, Pages 1364-1370

  Oh, Se Woong ^a,b   Kim, Dae Hoon ^b   Ha, Jong Ryul ^b   Kim, Dae Yong ^a  

^a Seoul National University   (South Korea)

^b Choongwae Pharma Co   (South Korea)

Author keywords

CW209292; Dimethylnitrosamine; Hepatic fibrosis; Methylenedioxybenzene; Rat

Indexed keywords

1,3 BENZODIOXOLE DERIVATIVE; ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CANCER GROWTH FACTOR; COLLAGEN TYPE 4; CW 209292; DIMETHYLNITROSAMINE; HYALURONIC ACID; HYDROXYPROLINE; MESSENGER RNA; SERUM ALBUMIN; UNCLASSIFIED DRUG;

ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MEGADOSE; DRUG SYNTHESIS; FEMALE; GENE EXPRESSION; HISTOLOGY; LIVER FIBROSIS; LIVER FUNCTION; LOW DRUG DOSE; MALE; NONHUMAN; PROTHROMBIN TIME; RAT; STELLATE CELL; TREATMENT DURATION;

ANIMALS; BENZODIOXOLES; BODY WEIGHT; CELL PROLIFERATION; DIMETHYLNITROSAMINE; DISEASE MODELS, ANIMAL; FEMALE; HEPATIC STELLATE CELLS; HYDROXYPROLINE; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CIRRHOSIS; MALE; MOLECULAR STRUCTURE; PROTHROMBIN TIME; RATS; RATS, SPRAGUE-DAWLEY; SURVIVAL ANALYSIS; THIAZOLES;

EID: 69149101801     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.1364     Document Type: Article

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