Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via β-catenin/TCF7L2 pathway in adult T cell leukemia cells

Cancer Letters

Volumn 284, Issue 1, 2009, Pages 62-70

  Kurashina, Ryosuke ^a,b   Ohyashiki, Junko H ^a   Kobayashi, Chiaki ^a   Hamamura, Ryoko ^a   Zhang, Yu ^a   Hirano, Toshihiko ^b   Ohyashiki, Kazuma ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

catenin; Adult T cell leukemia lymphoma; Heat shock protein 90; Microarray

Indexed keywords

17 DEMETHOXY 17 (2 DIMETHYLAMINOETHYLAMINO)GELDANAMYCIN; BETA CATENIN; BIOLOGICAL MARKER; BIRC5 PROTEIN; CUTANEOUS T CELL ATTRACTING CHEMOKINE; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; INTERLEUKIN 9; PROTEIN BCL 2; PROTEIN KINASE B; TANESPIMYCIN; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; IC 50; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; T CELL LEUKEMIA; UBIQUITINATION; UPREGULATION;

ANTINEOPLASTIC AGENTS; BENZOQUINONES; BETA CATENIN; CELL PROLIFERATION; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; LEUKEMIA-LYMPHOMA, ADULT T-CELL; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS;

HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 69049106387     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.04.012     Document Type: Article

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