Chaperoning cell death: A critical dual role for Hsp90 in small-cell lung cancer

Nature Chemical Biology

Volumn 3, Issue 8, 2007, Pages 455-457

  Workman, Paul ^a   Powers, Marissa V ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; 17 DIMETHYLAMINOETHYLAMINO 17 DEMETHOXYGELDANAMYCIN; 8 (2 CHLORO 3,4,5 TRIMETHOXYBENZYL) 2 FLUORO 9 (PENT 4 YNYL) 9H PURIN 6 AMINE; ANSAMYCIN DERIVATIVE; BENZOQUINONE; CNF 2024; CYCLOPROPARADICICOL; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; HORMONE RECEPTOR; KNK 437; MAL 3 101; PU 24FCI; RADICICOL; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; CELL CYCLE ARREST; CELL DEATH; CYTOLOGY; DROSOPHILA MELANOGASTER; ENVIRONMENTAL STRESS; HUMAN; LUNG SMALL CELL CANCER; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY;

EID: 34447550488     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio0807-455     Document Type: Short Survey

References (13)

1. McDonald, E., Jones, J. & Workman, P. Curr. Top. Med. Chem. 6, 1091-1107 (2006).
2. Chiosis, G., Caldas Lopez, E. & Solit, D. Curr. Opin. Investig. Drugs 7, 534-541 (2006).
3. Pacey, S., Banerji, U., Judson, I. & Workman, P. Handb. Exp. Pharmacol. 172, 331-358 (2006).
4. Workman, P., Neckers, L., Burrows, F. & Rosen, N. Ann. NY Acad. Sci., published online 18 May 2007 (doi:10.1196/annals1391.012).
5. Rodina, A. et al. Nat. Chem. Biol. 3, 498-507 (2007).
6. Ritossa, F. Cell Stress Chaperones 1, 97-98 (1996).
7. Westerheide, S.D. & Morimoto, R.I. J. Biol. Chem. 280, 33097-33100 (2005).
8. Kamal, A. et al. Nature 425, 407-410 (2003).
9. Chiosis, G. & Neckers, L. ACS. Chem. Biol. 1, 279-284 (2006).
10. Pearl, L.H. & Prodromou, C. Annu. Rev. Biochem. 75, 271-294 (2006).
11. Hostein, I. et al. Cancer Res. 61, 4003-4009 (2001).
12. Banerji, U. et al. Clin. Cancer Res. 11, 7023-7032 (2005).
13. Nylansted, J. et al. Cancer Res. 62, 7139-7142 (2002).