Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling

Biochemical and Biophysical Research Communications

Volumn 352, Issue 4, 2007, Pages 896-902

  Taniguchi, Koji ^a,b   Ayada, Toranoshin ^a   Ichiyama, Kenji ^a   Kohno, Ri ichiro ^c   Yonemitsu, Yoshikazu ^c,d   Minami, Yasuhiro ^e   Kikuchi, Akira ^f   Maehara, Yoshihiko ^b   Yoshimura, Akihiko ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e KOBE UNIVERSITY   (Japan)

^f HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Embryonic development; FGF; Knockout mouse; Negative regulation; Signal transduction; Sprouty

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; SPROUTY 2 PROTEIN; SPROUTY 4 PROTEIN; SPROUTY PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; FIBROBLAST; GENE TARGETING; GENETIC CODE; GROWTH RETARDATION; INHIBITION KINETICS; JAW MALFORMATION; KNOCKOUT MOUSE; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; SYNDACTYLY;

ANIMALS; BODY WEIGHT; CELLS, CULTURED; EMBRYO; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, LETHAL; LUNG; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; PHENOTYPE; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES;

MAMMALIA;

EID: 33845412960     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.11.107     Document Type: Article

References (30)

1. Kim H.J., and Bar-Sagi D. Modulation of signalling by Sprouty: a developing story. Nat. Rev. Mol. Cell Biol. 5 (2004) 441-450
2. Mason J.M., Morrison D.J., Basson M.A., and Licht J.D. Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. Trends Cell Biol. 16 (2006) 45-54
3. Wakioka T., Sasaki A., Kato R., Shouda T., Matsumoto A., Miyoshi K., Tsuneoka M., Komiya S., Baron R., and Yoshimura A. Spred is a Sprouty-related suppressor of Ras signalling. Nature 412 (2001) 647-651
4. Nonami A., Kato R., Taniguchi K., Yoshiga D., Taketomi T., Fukuyama S., Harada M., Sasaki A., and Yoshimura A. Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells. J. Biol. Chem. 279 (2004) 52543-52551
5. Sivak J.M., Petersen L.F., and Amaya E. FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation. Dev. Cell 8 (2005) 689-701
6. Perl A.K., Hokuto I., Impagnatiello M.A., Christofori G., and Whitsett J.A. Temporal effects of Sprouty on lung morphogenesis. Dev. Biol 258 (2003) 154-168
7. Minowada G., Jarvis L.A., Chi C.L., Neubuser A., Sun X., Hacohen N., Krasnow M.A., and Martin G.R. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126 (1999) 4465-4475
8. Basson M.A., Akbulut S., Watson-Johnson J., Simon R., Carroll T.J., Shakya R., Gross I., Martin G.R., Lufkin T., McMahon A.P., Wilson P.D., Costantini F.D., Mason I.J., and Licht J.D. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev. Cell 8 (2005) 229-239
9. Taketomi T., Yoshiga D., Taniguchi K., Kobayashi T., Nonami A., Kato R., Sasaki M., Sasaki A., Ishibashi H., Moriyama M., Nakamura K., Nishimura J., and Yoshimura A. Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia. Nat. Neurosci. 8 (2005) 855-857
10. Shim K., Minowada G., Coling D.E., Martin G.R., Sprouty2, and gene a.m.d. regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev. Cell 8 (2005) 553-564
11. Hansen J., Floss T., Van Sloun P., Fuchtbauer E.M., Vauti F., Arnold H.H., Schnutgen F., Wurst W., von Melchner H., and Ruiz P. A large-scale gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc. Natl. Acad. Sci. USA 100 (2003) 9918-9922
12. Klein O.D., Minowada G., Peterkova R., Kangas A., Yu B.D., Lesot H., Peterka M., Jernvall J., and Martin G.R. Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev. Cell 11 (2006) 181-190
13. Sasaki A., Taketomi T., Wakioka T., Kato R., and Yoshimura A. Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation. J. Biol. Chem. 276 (2001) 36804-36808
14. Bundschu K., Knobeloch K.P., Ullrich M., Schinke T., Amling M., Engelhardt C.M., Renne T., Walter U., and Schuh K. Gene disruption of Spred-2 causes dwarfism. J. Biol. Chem. 280 (2005) 28572-28580
15. Tao H., Ono K., Kurose H., Noji S., and Ohuchi H. Exogenous FGF10 can rescue an eye-open at birth phenotype of Fgf10-null mice by activating activin and TGFalpha-EGFR signaling. Dev. Growth Differ. 48 (2006) 339-346
16. Zhang S., Lin Y., Itaranta P., Yagi A., and Vainio S. Expression of Sprouty genes 1, 2 and 4 during mouse organogenesis. Mech. Dev. 109 (2001) 367-370
17. Tefft J.D., Lee M., Smith S., Leinwand M., Zhao J., Bringas Jr. P., Crowe D.L., and Warburton D. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr. Biol. 9 (1999) 219-222
18. Katoh Y., and Katoh M. FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells. Int. J. Mol. Med. 17 (2006) 529-532
19. Winn R.A., Marek L., Han S.Y., Rodriguez K., Rodriguez N., Hammond M., Van Scoyk M., Acosta H., Mirus J., Barry N., Bren-Mattison Y., Van Raay T.J., Nemenoff R.A., and Heasley L.E. Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation. J. Biol. Chem. 280 (2005) 19625-19634
20. Yamagishi C., Yamagishi H., Maeda J., Tsuchihashi T., Ivey K., Hu T., and Srivastava D. Sonic hedgehog is essential for first pharyngeal arch development. Pediatr. Res. 59 (2006) 349-354
21. Wilkie A.O., Slaney S.F., Oldridge M., Poole M.D., Ashworth G.J., Hockley A.D., Hayward R.D., David D.J., Pulleyn L.J., Rutland P., et al. Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome. Nat. Genet. 9 (1995) 165-172
22. Coffin J.D., Florkiewicz R.Z., Neumann J., Mort-Hopkins T., Dorn II G.W., Lightfoot P., German R., Howles P.N., Kier A., O'Toole B.A., et al. Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice. Mol. Biol. Cell 6 (1995) 1861-1873
23. Garofalo S., Kliger-Spatz M., Cooke J.L., Wolstin O., Lunstrum G.P., Moshkovitz S.M., Horton W.A., and Yayon A. Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice. J. Bone Miner Res. 14 (1999) 1909-1915
24. Naski M.C., and Ornitz D.M. FGF signaling in skeletal development. Front. Biosci. 3 (1998) d781-d794
25. Murakami S., Balmes G., McKinney S., Zhang Z., Givol D., and de Crombrugghe B. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes Dev. 18 (2004) 290-305
26. Yu K., Herr A.B., Waksman G., and Ornitz D.M. Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome. Proc. Natl. Acad. Sci. USA 97 (2000) 14536-14541
27. Moon A.M., and Capecchi M.R. Fgf8 is required for outgrowth and patterning of the limbs. Nat. Genet 26 (2000) 455-459
28. Lewandoski M., Sun X., and Martin G.R. Fgf8 signalling from the AER is essential for normal limb development. Nat. Genet. 26 (2000) 460-463
29. Trumpp A., Depew M.J., Rubenstein J.L., Bishop J.M., and Martin G.R. Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev. 13 (1999) 3136-3148
30. Lebeche D., Malpel S., and Cardoso W.V. Fibroblast growth factor interactions in the developing lung. Mech. Dev. 86 (1999) 125-136