Reactivation of human brain homogenate cholinesterases inhibited by tabun using newly developed oximes K117 and K127

Basic and Clinical Pharmacology and Toxicology

Volumn 105, Issue 3, 2009, Pages 207-210

  Kuca, Kamil ^a,b,e   Cabal, Jiri ^b   Jung, Yung Sik ^c   Musilek, Kamil ^b   Soukup, Ondrej ^b   Jun, Daniel ^a,b   Pohanka, Miroslav ^a   Musilova, Lucie ^d   Karasová, Jana ^b   Novotný, Ladislav ^a   Hrabinova, Martina ^a  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

^c Korea Research Institute of Chemical Technology   (South Korea)

^d Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^e J E PURKINJE UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 5 (4 CARBAMOYLPYRIDINIUM) 3 OXAPENTANE DIBROMIDE; 1,5 BIS(4 HYDROXYIMINOMETHYLPYRIDINIUM) 3 OXAPENTANE DICHLORIDE; ACETYLCHOLINESTERASE; CHOLINESTERASE REACTIVATOR; K 117; K 127; OXIME DERIVATIVE; PRALIDOXIME; TABUN; TRIMEDOXIME; UNCLASSIFIED DRUG;

AGED; ARTICLE; BRAIN HOMOGENATE; CAUDATE NUCLEUS; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME REACTIVATION; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

AGED; BRAIN; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; HUMANS; MALE; OXIMES; PHOSPHORIC ACID ESTERS; PYRIDINIUM COMPOUNDS;

ANIMALIA;

EID: 68949205894     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2009.00421.x     Document Type: Article

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