메뉴 건너뛰기




Volumn 388, Issue 1, 2009, Pages 79-85

Functional elements in the minimal promoter of the human proton-coupled folate transporter

Author keywords

Folates; Gene expression; Hereditary folate malabsorption; Promoter; Transport

Indexed keywords

FOLIC ACID; LUCIFERASE; PROTON; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR YY1;

EID: 68949159799     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.07.116     Document Type: Article
Times cited : (22)

References (21)
  • 1
    • 52049094603 scopus 로고    scopus 로고
    • Molecular mechanisms of adaptation to folate deficiency
    • Ifergan I., and Assaraf Y.G. Molecular mechanisms of adaptation to folate deficiency. Vitam. Horm. 79 (2008) 99-143
    • (2008) Vitam. Horm. , vol.79 , pp. 99-143
    • Ifergan, I.1    Assaraf, Y.G.2
  • 2
    • 0041305877 scopus 로고    scopus 로고
    • Membrane transport of folates
    • Matherly L.H., and Goldman D.I. Membrane transport of folates. Vitam. Horm. 66 (2003) 403-456
    • (2003) Vitam. Horm. , vol.66 , pp. 403-456
    • Matherly, L.H.1    Goldman, D.I.2
  • 3
    • 33947375647 scopus 로고    scopus 로고
    • Molecular basis of antifolate resistance
    • Assaraf Y.G. Molecular basis of antifolate resistance. Cancer Metastasis Rev. 26 (2007) 153-181
    • (2007) Cancer Metastasis Rev. , vol.26 , pp. 153-181
    • Assaraf, Y.G.1
  • 5
    • 0028889010 scopus 로고
    • Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells
    • Henderson G.B., Hughes T.R., and Saxena M. Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells. Arch. Biochem. Biophys. 316 (1995) 77-82
    • (1995) Arch. Biochem. Biophys. , vol.316 , pp. 77-82
    • Henderson, G.B.1    Hughes, T.R.2    Saxena, M.3
  • 6
    • 0032499415 scopus 로고    scopus 로고
    • Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function
    • Sierra E.E., and Goldman I.D. Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function. Biochem. Pharmacol. 55 (1998) 1505-1512
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1505-1512
    • Sierra, E.E.1    Goldman, I.D.2
  • 7
    • 0032478639 scopus 로고    scopus 로고
    • Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in Chinese hamster ovary cells
    • Assaraf Y.G., Babani S., and Goldman I.D. Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in Chinese hamster ovary cells. J. Biol. Chem. 273 (1998) 8106-8111
    • (1998) J. Biol. Chem. , vol.273 , pp. 8106-8111
    • Assaraf, Y.G.1    Babani, S.2    Goldman, I.D.3
  • 8
    • 59849093173 scopus 로고    scopus 로고
    • Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues
    • Zhao R., Matherly L.H., and Goldman I.D. Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues. Expert Rev. Mol. Med. 11 (2009) e4
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Zhao, R.1    Matherly, L.H.2    Goldman, I.D.3
  • 9
    • 34548026299 scopus 로고    scopus 로고
    • The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption
    • Zhao R., Min S.H., Qiu A., Sakaris A., Goldberg G.L., Sandoval C., Malatack J.J., Rosenblatt D.S., and Goldman I.D. The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption. Blood 110 (2007) 1147-1152
    • (2007) Blood , vol.110 , pp. 1147-1152
    • Zhao, R.1    Min, S.H.2    Qiu, A.3    Sakaris, A.4    Goldberg, G.L.5    Sandoval, C.6    Malatack, J.J.7    Rosenblatt, D.S.8    Goldman, I.D.9
  • 10
    • 52649117496 scopus 로고    scopus 로고
    • A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function
    • Lasry I., Berman B., Straussberg R., Sofer Y., Bessler H., Sharkia M., Glaser F., Jansen G., Drori S., and Assaraf Y.G. A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function. Blood 112 (2008) 2055-2061
    • (2008) Blood , vol.112 , pp. 2055-2061
    • Lasry, I.1    Berman, B.2    Straussberg, R.3    Sofer, Y.4    Bessler, H.5    Sharkia, M.6    Glaser, F.7    Jansen, G.8    Drori, S.9    Assaraf, Y.G.10
  • 11
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E., Matthias P., Muller M.M., and Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17 (1989) 6419
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 12
    • 0022449158 scopus 로고
    • Sequence-specific interactions of nuclear factors with the insulin gene enhancer
    • Ohlsson H., and Edlund T. Sequence-specific interactions of nuclear factors with the insulin gene enhancer. Cell 45 (1986) 35-44
    • (1986) Cell , vol.45 , pp. 35-44
    • Ohlsson, H.1    Edlund, T.2
  • 13
    • 53449097226 scopus 로고    scopus 로고
    • PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells
    • Gonen N., Bram E.E., and Assaraf Y.G. PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells. Biochem. Biophys. Res. Commun. 376 (2008) 787-792
    • (2008) Biochem. Biophys. Res. Commun. , vol.376 , pp. 787-792
    • Gonen, N.1    Bram, E.E.2    Assaraf, Y.G.3
  • 14
    • 0035794180 scopus 로고    scopus 로고
    • The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression
    • Whetstine J.R., and Matherly L.H. The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression. J. Biol. Chem. 276 (2001) 6350-6358
    • (2001) J. Biol. Chem. , vol.276 , pp. 6350-6358
    • Whetstine, J.R.1    Matherly, L.H.2
  • 15
    • 33847206418 scopus 로고    scopus 로고
    • R5020 and RU486 act as progesterone receptor agonists to enhance Sp1/Sp4-dependent gene transcription by an indirect mechanism
    • Shatnawi A., Tran T., and Ratnam M. R5020 and RU486 act as progesterone receptor agonists to enhance Sp1/Sp4-dependent gene transcription by an indirect mechanism. Mol. Endocrinol. 21 (2007) 635-650
    • (2007) Mol. Endocrinol. , vol.21 , pp. 635-650
    • Shatnawi, A.1    Tran, T.2    Ratnam, M.3
  • 16
    • 0026549002 scopus 로고
    • Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitor
    • O'Connor B.M., Jackman A.L., Crossley P.H., Freemantle S.E., Lunec J., and Calvert A.H. Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitor. Cancer Res. 52 (1992) 1137-1143
    • (1992) Cancer Res. , vol.52 , pp. 1137-1143
    • O'Connor, B.M.1    Jackman, A.L.2    Crossley, P.H.3    Freemantle, S.E.4    Lunec, J.5    Calvert, A.H.6
  • 17
    • 0030750738 scopus 로고    scopus 로고
    • Identification of functional elements in the promoter region of the human gene for thymidylate synthase and nuclear factors that regulate the expression of the gene
    • Horie N., and Takeishi K. Identification of functional elements in the promoter region of the human gene for thymidylate synthase and nuclear factors that regulate the expression of the gene. J. Biol. Chem. 272 (1997) 18375-18381
    • (1997) J. Biol. Chem. , vol.272 , pp. 18375-18381
    • Horie, N.1    Takeishi, K.2
  • 18
    • 0029819751 scopus 로고    scopus 로고
    • YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity
    • O'Connor M.J., Tan S.H., Tan C.H., and Bernard H.U. YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity. J. Virol. 70 (1996) 6529-6539
    • (1996) J. Virol. , vol.70 , pp. 6529-6539
    • O'Connor, M.J.1    Tan, S.H.2    Tan, C.H.3    Bernard, H.U.4
  • 20
    • 34250376736 scopus 로고    scopus 로고
    • Synergistic activation of the tumor suppressor, HLJ1, by the transcription factors YY1 and activator protein 1
    • Wang C.C., Tsai M.F., Dai T.H., Hong T.M., Chan W.K., Chen J.J., and Yang P.C. Synergistic activation of the tumor suppressor, HLJ1, by the transcription factors YY1 and activator protein 1. Cancer Res. 67 (2007) 4816-4826
    • (2007) Cancer Res. , vol.67 , pp. 4816-4826
    • Wang, C.C.1    Tsai, M.F.2    Dai, T.H.3    Hong, T.M.4    Chan, W.K.5    Chen, J.J.6    Yang, P.C.7
  • 21
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E., and Karin M. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4 (2002) E131-E136
    • (2002) Nat. Cell Biol. , vol.4
    • Shaulian, E.1    Karin, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.