Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia

Journal of Immunology

Volumn 183, Issue 1, 2009, Pages 670-676

  Ventura, Grasiella M De C ^a,b   Balloy, Viviane ^a,b   Ramphal, Reuben ^c   Khun, Huot ^a   Huerre, Michel ^a   Ryffel, Bernhard ^d   Plotkowski, Maria Cristina M ^e   Chignard, Michel ^a,b   Si Tahar, Mustapha ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d UNIVERSITÉ D'ORLÉANS   (France)

^e STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CORTISONE ACETATE; CXCL3 CHEMOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MYELOID DIFFERENTIATION FACTOR 88; TUMOR NECROSIS FACTOR ALPHA; IMMUNOSUPPRESSIVE AGENT; MYD88 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COUNT; BLOOD; BURKHOLDERIA CENOCEPACIA; BURKHOLDERIA INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HOST; IMMUNITY; IMMUNOCOMPROMISED PATIENT; LUNG; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; SURVIVAL; WILD TYPE; ANIMAL; BACTERIAL PNEUMONIA; BURKHOLDERIA CEPACIA; C57BL MOUSE; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNE DEFICIENCY; IMMUNOLOGY; MOUSE MUTANT; OPPORTUNISTIC INFECTION; PATHOGENICITY; PHYSIOLOGY;

ANIMALS; BURKHOLDERIA CEPACIA; BURKHOLDERIA INFECTIONS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; OPPORTUNISTIC INFECTIONS; PNEUMONIA, BACTERIAL; SURVIVAL ANALYSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 68949137063     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0801497     Document Type: Article

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