Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T

Channels

Volumn 3, Issue 4, 2009, Pages 261-269

  Jarecki, Brian W ^a   Sheets, Patrick L ^a   Xiao, Yucheng ^a   Jackson II, James O ^a   Cummins, Theodore R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative splicing; Electrophysiology; Erythromelalgia; Nav1.7; Paroxysmal extreme pain disorder; Sodium channels

Indexed keywords

CYCLIC AMP; CYCLIC NUCLEOTIDE GATED CHANNEL; ISOPROTEIN; TETRATRICOPEPTIDE REPEAT CONTAINING RAB8B INTERACTING PROTEIN; TETRATRICOPEPTIDE REPEAT PROTEIN; UNCLASSIFIED DRUG;

ACTION POTENTIAL; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CELL SURFACE; DOWN REGULATION; ENDOCYTOSIS; HEART AUTOMATICITY; HUMAN; HYPERPOLARIZATION; MEMBRANE DEPOLARIZATION; MUTATION; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; SINUS NODE;

EID: 68949131011     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.3.4.9341     Document Type: Article

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