Human placenta expresses and secretes NKG2D ligands via exosomes that down-modulate the cognate receptor expression: Evidence for immunosuppressive function

Journal of Immunology

Volumn 183, Issue 1, 2009, Pages 340-351

  Hedlund, Malin ^a   Stenqvist, Ann Christin ^a   Nagaeva, Olga ^a   Kjellberg, Lennart ^a   Wulff, Marianne ^a   Baranov, Vladimir ^a   Mincheva Nilsson, Lucia ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR NKG2D; PERFORIN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; PLACENTA PROTEIN; SIGNAL PEPTIDE; ULBP2 PROTEIN, HUMAN;

ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; CYTOTOXICITY; DOWN REGULATION; EXOSOME; EXPLANT; FEMALE; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SYNCYTIOTROPHOBLAST; BIOSYNTHESIS; CYTOTOXIC T LYMPHOCYTE; DRUG ANTAGONISM; ENDOSOME; GENETICS; IMMUNOLOGY; METABOLISM; ORGAN CULTURE TECHNIQUE; PREGNANCY; SECRETION; ULTRASTRUCTURE;

DOWN-REGULATION; ENDOSOMES; EXOSOMES; FEMALE; HUMANS; IMMUNOSUPPRESSION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; ORGAN CULTURE TECHNIQUES; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 68949117871     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803477     Document Type: Article

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