메뉴 건너뛰기




Volumn 21, Issue 9, 2009, Pages

Selective lack of tolerance to delayed gastric emptying after daily administration of WIN 55,212-2 in the rat

Author keywords

Cannabinoid; Gastrointestinal motility; Radiology; Rat; Tolerance

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID; CANNABINOID 1 RECEPTOR ANTAGONIST;

EID: 68949102282     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2009.01315.x     Document Type: Article
Times cited : (35)

References (61)
  • 2
    • 46049119745 scopus 로고    scopus 로고
    • Adverse effects of medical cannabinoids: A systematic review
    • Wang T, Collet JP, Shapiro S, Ware MA. Adverse effects of medical cannabinoids: a systematic review. CMAJ 2008 178 : 1669 78.
    • (2008) CMAJ , vol.178 , pp. 1669-78
    • Wang, T.1    Collet, J.P.2    Shapiro, S.3    Ware, M.A.4
  • 4
    • 0027501457 scopus 로고
    • Cannabinoid structure-activity relationships: Correlation of receptor binding and in vivo activities
    • Compton DR, Rice KC, De Costa BR et al. Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities. J Pharmacol Exp Ther 1993 265 : 218 26.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 218-26
    • Compton, D.R.1    Rice, K.C.2    De Costa, B.R.3
  • 5
    • 0035059241 scopus 로고    scopus 로고
    • The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain
    • Fox A, Kesingland A, Gentry C et al. The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain. Pain 2001 92 : 91 100.
    • (2001) Pain , vol.92 , pp. 91-100
    • Fox, A.1    Kesingland, A.2    Gentry, C.3
  • 6
    • 0242643759 scopus 로고    scopus 로고
    • Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats
    • García MC, Adler-Graschinsky E, Celuch SM. Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats. Naunyn Schmiedebergs Arch Pharmacol 2003 368 : 270 6.
    • (2003) Naunyn Schmiedebergs Arch Pharmacol , vol.368 , pp. 270-6
    • García, M.C.1    Adler-Graschinsky, E.2    Celuch, S.M.3
  • 7
    • 0037338753 scopus 로고    scopus 로고
    • Anandamide-induced depressor effect in spontaneously hypertensive rats: Role of the vanilloid receptor
    • Li J, Kaminski NE, Wang DH. Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. Hypertension 2003 41 : 757 62.
    • (2003) Hypertension , vol.41 , pp. 757-62
    • Li, J.1    Kaminski, N.E.2    Wang, D.H.3
  • 9
    • 0036838392 scopus 로고    scopus 로고
    • Cardiovascular system effects of marijuana
    • Jones RT. Cardiovascular system effects of marijuana. J Clin Pharmacol 2002 42 : 58S 63S.
    • (2002) J Clin Pharmacol , vol.42
    • Jones, R.T.1
  • 10
    • 0036839338 scopus 로고    scopus 로고
    • Cardiovascular consequences of marijuana use
    • Sidney S. Cardiovascular consequences of marijuana use. J Clin Pharmacol 2002 42 : 64S 70S.
    • (2002) J Clin Pharmacol , vol.42
    • Sidney, S.1
  • 11
    • 55449136749 scopus 로고    scopus 로고
    • Vasorelaxation caused by cannabinoids: Mechanisms in different vascular beds
    • López-Miranda V, Herradon E, Martín MI. Vasorelaxation caused by cannabinoids: mechanisms in different vascular beds. Curr Vasc Pharmacol 2008 6 : 335 46.
    • (2008) Curr Vasc Pharmacol , vol.6 , pp. 335-46
    • López-Miranda, V.1    Herradon, E.2    Martín, M.I.3
  • 13
    • 0024370916 scopus 로고
    • Psychoactive cannabinoids reduce gastrointestinal propulsion and motility in rodents
    • Shook JE, Burks TF. Psychoactive cannabinoids reduce gastrointestinal propulsion and motility in rodents. J Pharmacol Exp Ther 1989 249 : 444 9.
    • (1989) J Pharmacol Exp Ther , vol.249 , pp. 444-9
    • Shook, J.E.1    Burks, T.F.2
  • 16
    • 0032803098 scopus 로고    scopus 로고
    • The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats
    • Izzo AA, Mascolo N, Pinto L, Capasso R, Capasso F. The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats. Eur J Pharmacol 1999 384 : 37 42.
    • (1999) Eur J Pharmacol , vol.384 , pp. 37-42
    • Izzo, A.A.1    Mascolo, N.2    Pinto, L.3    Capasso, R.4    Capasso, F.5
  • 17
    • 0035010955 scopus 로고    scopus 로고
    • Cannabinoids and the gastrointestinal tract
    • Pertwee RG. Cannabinoids and the gastrointestinal tract. Gut 2001 48 : 859 67.
    • (2001) Gut , vol.48 , pp. 859-67
    • Pertwee, R.G.1
  • 18
    • 0037118910 scopus 로고    scopus 로고
    • Modulation of gastric emptying and gastrointestinal transit in rats through intestinal cannabinoid CB1 receptors
    • Landi M, Croci T, Rinaldi-Carmona M, Maffrand J-P, Le FurG, Manara L. Modulation of gastric emptying and gastrointestinal transit in rats through intestinal cannabinoid CB1 receptors. Eur J Pharmacol 2002 450 : 77 83.
    • (2002) Eur J Pharmacol , vol.450 , pp. 77-83
    • Landi, M.1    Croci, T.2    Rinaldi-Carmona, M.3    Maffrand, J.-P.4    Le, F.G.5    Manara, L.6
  • 19
    • 0032940913 scopus 로고    scopus 로고
    • Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: A double-blind, randomized study
    • McCallum RW, Soykan I, Sridhar KR, Ricci DA, Lange RC, Plankey MW. Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study. Aliment Pharmacol Ther 1999 13 : 77 80.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 77-80
    • McCallum, R.W.1    Soykan, I.2    Sridhar, K.R.3    Ricci, D.A.4    Lange, R.C.5    Plankey, M.W.6
  • 20
    • 33746878457 scopus 로고    scopus 로고
    • Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: A randomized, placebo-controlled study
    • Esfandyari T, Camilleri M, Ferber I, Burton D, Baxter K, Zinsmeister AR. Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study. Neurogastroenterol Motil 2006 18 : 831 8.
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 831-8
    • Esfandyari, T.1    Camilleri, M.2    Ferber, I.3    Burton, D.4    Baxter, K.5    Zinsmeister, A.R.6
  • 21
    • 0033995911 scopus 로고    scopus 로고
    • Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil
    • Izzo AA, Pinto L, Borrelli F, Capasso R, Mascolo N, Capasso F. Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil. Br J Pharmacol 2000 129 : 1627 32.
    • (2000) Br J Pharmacol , vol.129 , pp. 1627-32
    • Izzo, A.A.1    Pinto, L.2    Borrelli, F.3    Capasso, R.4    Mascolo, N.5    Capasso, F.6
  • 22
    • 0026560734 scopus 로고
    • Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine
    • Pertwee RG, Stevenson LA, Elrick DB, Mechoulam R, Corbett AD. Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine. Br J Pharmacol 1992 105 : 980 4.
    • (1992) Br J Pharmacol , vol.105 , pp. 980-4
    • Pertwee, R.G.1    Stevenson, L.A.2    Elrick, D.B.3    Mechoulam, R.4    Corbett, A.D.5
  • 23
    • 0029786781 scopus 로고    scopus 로고
    • Further evidence for the presence of cannabinoid CB1 receptors in guinea-pig small intestine
    • Pertwee RG, Fernando SR, Nash JE, Coutts AA. Further evidence for the presence of cannabinoid CB1 receptors in guinea-pig small intestine. Br J Pharmacol 1996 118 : 2199 205.
    • (1996) Br J Pharmacol , vol.118 , pp. 2199-205
    • Pertwee, R.G.1    Fernando, S.R.2    Nash, J.E.3    Coutts, A.A.4
  • 24
    • 0030814261 scopus 로고    scopus 로고
    • Inhibition by cannabinoid receptor agonists of acetylcholine release from the guinea-pig myenteric plexus
    • Coutts AA, Pertwee RG. Inhibition by cannabinoid receptor agonists of acetylcholine release from the guinea-pig myenteric plexus. Br J Pharmacol 1997 121 : 1557 66.
    • (1997) Br J Pharmacol , vol.121 , pp. 1557-66
    • Coutts, A.A.1    Pertwee, R.G.2
  • 25
    • 0033626501 scopus 로고    scopus 로고
    • Localization of CB1-cannabinoid receptor immunoreactivity in the porcine enteric nervous system
    • Kulkarni-Narla A, Brown DR. Localization of CB1-cannabinoid receptor immunoreactivity in the porcine enteric nervous system. Cell Tissue Res 2000 302 : 73 80.
    • (2000) Cell Tissue Res , vol.302 , pp. 73-80
    • Kulkarni-Narla, A.1    Brown, D.R.2
  • 26
    • 0037043150 scopus 로고    scopus 로고
    • Localisation of cannabinoid CB1 receptor immunoreactivity in the guinea pig and rat myenteric plexus
    • Coutts AA, Irving AJ, Mackie K, Pertwee RG, Anavi-Goffer S. Localisation of cannabinoid CB1 receptor immunoreactivity in the guinea pig and rat myenteric plexus. J Comp Neurol 2002 448 : 410 22.
    • (2002) J Comp Neurol , vol.448 , pp. 410-22
    • Coutts, A.A.1    Irving, A.J.2    MacKie, K.3    Pertwee, R.G.4    Anavi-Goffer, S.5
  • 27
  • 28
    • 0018974873 scopus 로고
    • Effects of chronic administration of delta-9-tertrahydrocannabinol on the cardiovascular system, and pressor and behavioural responses to brain stimulation in freely moving rats
    • Kawasaki H, Watanabe S, Ueki S. Effects of chronic administration of delta-9-tertrahydrocannabinol on the cardiovascular system, and pressor and behavioural responses to brain stimulation in freely moving rats. Eur J Phramacol 1980 65 : 63 9.
    • (1980) Eur J Phramacol , vol.65 , pp. 63-9
    • Kawasaki, H.1    Watanabe, S.2    Ueki, S.3
  • 29
    • 0017068782 scopus 로고
    • Tolerance to the cardiovascular effects of delta- 9-tetrahydrocannabinol in the rat
    • Adams MD, Chait LD, Earnhardt JT. Tolerance to the cardiovascular effects of delta- 9-tetrahydrocannabinol in the rat. Br J Pharmacol 1976 56 : 43 8.
    • (1976) Br J Pharmacol , vol.56 , pp. 43-8
    • Adams, M.D.1    Chait, L.D.2    Earnhardt, J.T.3
  • 30
    • 0016594389 scopus 로고
    • Tolerance to the effects of delta 9-tetrahydrocannabinol in mice on intestinal motility, temperature and locomotor activity
    • Anderson PF, Jackson DM, Chesher GB, Malor R. Tolerance to the effects of delta 9-tetrahydrocannabinol in mice on intestinal motility, temperature and locomotor activity. Psychopharmacologia 1975 43 : 31 6.
    • (1975) Psychopharmacologia , vol.43 , pp. 31-6
    • Anderson, P.F.1    Jackson, D.M.2    Chesher, G.B.3    Malor, R.4
  • 31
    • 0032991855 scopus 로고    scopus 로고
    • Cross-tolerance and convergent dependence between morphine and cannabimimetic agent WIN 55,212-2 in the guinea-pig ileum myenteric plexus
    • Basilico L, Parolaro D, Coleoni M, Costa B, Giagnoni G. Cross-tolerance and convergent dependence between morphine and cannabimimetic agent WIN 55,212-2 in the guinea-pig ileum myenteric plexus. Eur J Pharmacol 1999 376 : 265 71.
    • (1999) Eur J Pharmacol , vol.376 , pp. 265-71
    • Basilico, L.1    Parolaro, D.2    Coleoni, M.3    Costa, B.4    Giagnoni, G.5
  • 32
    • 33747143081 scopus 로고    scopus 로고
    • Tolerance to cannabinoid response on the myenteric plexus of guinea-pig ileum and human small intestinal strips
    • Guagnini F, Cogliati P, Mukenge S, Ferla G, Croci T. Tolerance to cannabinoid response on the myenteric plexus of guinea-pig ileum and human small intestinal strips. Br J Pharmacol 2006 148 : 1165 73.
    • (2006) Br J Pharmacol , vol.148 , pp. 1165-73
    • Guagnini, F.1    Cogliati, P.2    Mukenge, S.3    Ferla, G.4    Croci, T.5
  • 33
    • 46749095880 scopus 로고    scopus 로고
    • Radiological study of gastrointestinal motor activity after acute cisplatin in the rat. Temporal relationship with pica
    • Cabezos PA, Vera G, Castillo M, Fernández-Pujol R, Martín MI, Abalo R. Radiological study of gastrointestinal motor activity after acute cisplatin in the rat. Temporal relationship with pica. Auton Neurosci 2008 141 : 54 65.
    • (2008) Auton Neurosci , vol.141 , pp. 54-65
    • Cabezos, P.A.1    Vera, G.2    Castillo, M.3    Fernández-Pujol, R.4    Martín, M.I.5    Abalo, R.6
  • 34
    • 68949090591 scopus 로고    scopus 로고
    • The cannabinoid agonist WIN 55,212-2 prevents the development of mechanical allodynia induced by chronic cisplatin in the rat
    • Martín MI, Vera G, Chiarlone A, Cabezos PA, Abalo R. The cannabinoid agonist WIN 55,212-2 prevents the development of mechanical allodynia induced by chronic cisplatin in the rat. Eur J Pain 2006 10 : S58.
    • (2006) Eur J Pain , vol.10 , pp. 58
    • Martín, M.I.1    Vera, G.2    Chiarlone, A.3    Cabezos, P.A.4    Abalo, R.5
  • 35
    • 34547410453 scopus 로고    scopus 로고
    • WIN 55,212-2 prevents mechanical allodynia but not alterations in feeding behaviour induced by chronic cisplatin in the rat
    • Vera G, Chiarlone A, Cabezos PA, Pascual D, Martín MI, Abalo R. WIN 55,212-2 prevents mechanical allodynia but not alterations in feeding behaviour induced by chronic cisplatin in the rat. Life Sci 2007 81 : 468 79.
    • (2007) Life Sci , vol.81 , pp. 468-79
    • Vera, G.1    Chiarlone, A.2    Cabezos, P.A.3    Pascual, D.4    Martín, M.I.5    Abalo, R.6
  • 36
    • 33749341230 scopus 로고    scopus 로고
    • AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain
    • Costa B, Sinicalco D, Trovato AE et al. AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain. Br J Pharmacol 2006 14 : 1022 32.
    • (2006) Br J Pharmacol , vol.14 , pp. 1022-32
    • Costa, B.1    Sinicalco, D.2    Trovato, A.E.3
  • 37
    • 27644549880 scopus 로고    scopus 로고
    • A cannabinoid agonist, WIN 55,212-2, reduces neuropathic nociception induced by paclitaxel in rats
    • Pascual D, Goicoechea C, Suardíaz M, Martín MI. A cannabinoid agonist, WIN 55,212-2, reduces neuropathic nociception induced by paclitaxel in rats. Pain 2005 118 : 23 34.
    • (2005) Pain , vol.118 , pp. 23-34
    • Pascual, D.1    Goicoechea, C.2    Suardíaz, M.3    Martín, M.I.4
  • 38
    • 0015174705 scopus 로고
    • Influence of (-) A9-trans-tetrahydrocannabinol and mescaline on the behaviour of rats submitted to food competition situations
    • Masur J, Martz RMW, Korte FJ, Bienik D. Influence of (-) A9-trans-tetrahydrocannabinol and mescaline on the behaviour of rats submitted to food competition situations. Psychopharmacologia 1971 22 : 187 94.
    • (1971) Psychopharmacologia , vol.22 , pp. 187-94
    • Masur, J.1    Martz, R.M.W.2    Korte, F.J.3    Bienik, D.4
  • 39
    • 0015255466 scopus 로고
    • Effects of ‡9-THC on the open-field activity of the rat
    • Drew WG, Miller LL, Wikler A. Effects of ‡9-THC on the open-field activity of the rat. Psychopharmacologia 1972 23 : 289 99.
    • (1972) Psychopharmacologia , vol.23 , pp. 289-99
    • Drew, W.G.1    Miller, L.L.2    Wikler, A.3
  • 40
    • 0015304408 scopus 로고
    • Some pharmacological and toxicological effects of I-trans-A8 and 1-trans-A9-tetrahydrocannabinol in laboratory rodents
    • Dewey WL, Harris LS, Kennedy JS. Some pharmacological and toxicological effects of I-trans-A8 and 1-trans-A9-tetrahydrocannabinol in laboratory rodents. Archs ilt Pharmacodwi Ther 1972 196 : 133 45.
    • (1972) Archs Ilt Pharmacodwi Ther , vol.196 , pp. 133-45
    • Dewey, W.L.1    Harris, L.S.2    Kennedy, J.S.3
  • 41
    • 0033917648 scopus 로고    scopus 로고
    • Endocannabinoids and vascular function
    • Hillard CJ. Endocannabinoids and vascular function. J Pharmacol Exp Ther 2000 29 : 27 32.
    • (2000) J Pharmacol Exp Ther , vol.29 , pp. 27-32
    • Hillard, C.J.1
  • 42
    • 18844419446 scopus 로고    scopus 로고
    • Effects of cannabinoids on neurotransmission
    • In. Pertwee, R.G. ed. Heidelberg. Springer-Verlag
    • Szabo B, Schlicker E. Effects of cannabinoids on neurotransmission. In : Pertwee RG, ed. Cannabinoids. Handbook of Experimental Pharmacology. Heidelberg : Springer-Verlag, 2005 : 327 65.
    • (2005) Cannabinoids. Handbook of Experimental Pharmacology. , pp. 327-65
    • Szabo, B.1    Schlicker, E.2
  • 44
    • 0035807698 scopus 로고    scopus 로고
    • Delta9 -tetrahydrocannabinol increases brain temperature and inverts circadian rhythms
    • Perron RR, Tyson RL, Sutherland GR. Delta9 -tetrahydrocannabinol increases brain temperature and inverts circadian rhythms. Neuroreport 2001 12 : 3791 4.
    • (2001) Neuroreport , vol.12 , pp. 3791-4
    • Perron, R.R.1    Tyson, R.L.2    Sutherland, G.R.3
  • 45
    • 0027196816 scopus 로고
    • Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: A quantitative autoradiographic study
    • Oviedo A, Glowa J, Herkenham M. Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study. Brain Res 1993 616 : 293 302.
    • (1993) Brain Res , vol.616 , pp. 293-302
    • Oviedo, A.1    Glowa, J.2    Herkenham, M.3
  • 46
    • 0142011997 scopus 로고    scopus 로고
    • Functional consequences of the repeated administration of Delta9-tetrahydrocannabinol in the rat
    • Whitlow CT, Freedland CS, Porrino LJ. Functional consequences of the repeated administration of Delta9-tetrahydrocannabinol in the rat. Drug Alcohol Depend 2003 71 : 169 77.
    • (2003) Drug Alcohol Depend , vol.71 , pp. 169-77
    • Whitlow, C.T.1    Freedland, C.S.2    Porrino, L.J.3
  • 47
    • 0035937453 scopus 로고    scopus 로고
    • Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN
    • 55212-2.
    • Aceto MD, Scates SM, Martin BB. Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55212-2. Eur J Pharmacol 2001 416 : 75 81.
    • (2001) Eur J Pharmacol , vol.416 , pp. 75-81
    • Aceto, M.D.1    Scates, S.M.2    Martin, B.B.3
  • 48
    • 0034677778 scopus 로고    scopus 로고
    • Effects of the cannabinoid receptor agonist, HU 210, on ingestive behaviour and body weight of rats
    • Giuliani D, Ottani A, Ferrari F. Effects of the cannabinoid receptor agonist, HU 210, on ingestive behaviour and body weight of rats. Eur J Pharmacol 2000 391 : 275 9.
    • (2000) Eur J Pharmacol , vol.391 , pp. 275-9
    • Giuliani, D.1    Ottani, A.2    Ferrari, F.3
  • 49
    • 65949095029 scopus 로고    scopus 로고
    • HU210-induced downregulation in cannabinoid CB1 receptor binding strongly correlates with body weight loss in the adult rat
    • DOI:.
    • Dalton VS, Wang H, Zavitsanou K. HU210-induced downregulation in cannabinoid CB1 receptor binding strongly correlates with body weight loss in the adult rat. Neurochem Res 2009 44. DOI :.
    • (2009) Neurochem Res , pp. 44
    • Dalton, V.S.1    Wang, H.2    Zavitsanou, K.3
  • 52
    • 0031825768 scopus 로고    scopus 로고
    • Excitatory transmission to the circular muscle of the guinea-pig ileum: Evidence for the involvement of cannabinoid CB1 receptors
    • Izzo AA, Mascolo N, Borrelli F, Capasso F. Excitatory transmission to the circular muscle of the guinea-pig ileum: evidence for the involvement of cannabinoid CB1 receptors. Br J Pharmacol 1998 124 : 1363 8.
    • (1998) Br J Pharmacol , vol.124 , pp. 1363-8
    • Izzo, A.A.1    Mascolo, N.2    Borrelli, F.3    Capasso, F.4
  • 53
    • 0032782137 scopus 로고    scopus 로고
    • Cannabinoid inhibition of guinea-pig intestinal peristalsis via inhibition of excitatory and activation of inhibitory neural pathways
    • Heinemann A, Shahbazian A, Holzer P. Cannabinoid inhibition of guinea-pig intestinal peristalsis via inhibition of excitatory and activation of inhibitory neural pathways. Neuropharmacology 1999 38 : 1289 97.
    • (1999) Neuropharmacology , vol.38 , pp. 1289-97
    • Heinemann, A.1    Shahbazian, A.2    Holzer, P.3
  • 54
    • 0034105846 scopus 로고    scopus 로고
    • Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum
    • Izzo AA, Mascolo N, Tonini M, Capasso F. Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum. Br J Pharmacol 2000 129 : 984 90.
    • (2000) Br J Pharmacol , vol.129 , pp. 984-90
    • Izzo, A.A.1    Mascolo, N.2    Tonini, M.3    Capasso, F.4
  • 55
    • 39149119622 scopus 로고    scopus 로고
    • Cannabinoid CB(1) receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle
    • Baldassano S, Serio R, Mule' F. Cannabinoid CB(1) receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle. Eur J Pharmacol 2008 582 : 132 8.
    • (2008) Eur J Pharmacol , vol.582 , pp. 132-8
    • Baldassano, S.1    Serio, R.2    Mule, F.3
  • 56
    • 20344402285 scopus 로고    scopus 로고
    • Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations
    • Abalo R, Rivera AJ, Vera G, Suardíaz M, Martín MI. Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations. Neurosci Lett 2005 383 : 176 81.
    • (2005) Neurosci Lett , vol.383 , pp. 176-81
    • Abalo, R.1    Rivera, A.J.2    Vera, G.3    Suardíaz, M.4    Martín, M.I.5
  • 57
    • 26844504226 scopus 로고    scopus 로고
    • Identification and functional characterization of brainstem cannabinoid CB2 receptors
    • Van Sickle MD, Duncan M, Kingsley PJ et al. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 2005 310 : 329 32.
    • (2005) Science , vol.310 , pp. 329-32
    • Van Sickle, M.D.1    Duncan, M.2    Kingsley, P.J.3
  • 58
    • 51149101671 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats
    • Duncan M, Mouihate A, Mackie K et al. Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. Am J Physiol Gastrointest Liver Physiol 2008 295 : G78 87.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295 , pp. 78-87
    • Duncan, M.1    Mouihate, A.2    MacKie, K.3
  • 59
    • 12744258029 scopus 로고    scopus 로고
    • Inverse agonism and neutral antagonism at cananbinoid CB1 receptor
    • Pertwee RG. Inverse agonism and neutral antagonism at cananbinoid CB1 receptor. Life Sci 2005 76 : 1307 24.
    • (2005) Life Sci , vol.76 , pp. 1307-24
    • Pertwee, R.G.1
  • 61
    • 0036307592 scopus 로고    scopus 로고
    • Endocannabinoids as physiological regulators of colonic propulsion in mice
    • Pinto L, Izzo AA, Cascio MG et al. Endocannabinoids as physiological regulators of colonic propulsion in mice. Gastroenterology 2002 123 : 227 34.
    • (2002) Gastroenterology , vol.123 , pp. 227-34
    • Pinto, L.1    Izzo, A.A.2    Cascio, M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.