메뉴 건너뛰기




Volumn 379, Issue 1-2, 2009, Pages 109-118

Effect of sodium caprate on the oral absorptions of danshensu and salvianolic acid B

Author keywords

Absorption enhancer; Bioavailability; Danshensu; Intestinal absorption; Salvianolic acid B; Sodium caprate

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; ATENOLOL; DECANOATE SODIUM; PENETRATION ENHANCING AGENT; SALVIANOLIC ACID B; UNCLASSIFIED DRUG;

EID: 68749116199     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.06.016     Document Type: Article
Times cited : (70)

References (48)
  • 1
    • 0027174290 scopus 로고
    • Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route
    • Anderberg E.K., Lindmark T., and Artursson P. Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route. Pharm. Res. 10 (1993) 857-864
    • (1993) Pharm. Res. , vol.10 , pp. 857-864
    • Anderberg, E.K.1    Lindmark, T.2    Artursson, P.3
  • 2
    • 0033816196 scopus 로고    scopus 로고
    • Intestinal permeation enhancers
    • Aungst B.J. Intestinal permeation enhancers. J. Pharm. Sci. 89 (2000) 429-442
    • (2000) J. Pharm. Sci. , vol.89 , pp. 429-442
    • Aungst, B.J.1
  • 3
    • 39349090988 scopus 로고    scopus 로고
    • Determination of fifteen bioactive components in Radix Rhizoma Salviae Miltiorrhizae by high-performance liquid chromatography with ultraviolet and mass spectrometric detection
    • Cao J., Wei Y.J., Qi L.W., Li P., Qian Z.M., Luo H.W., Chen J., and Zhao J. Determination of fifteen bioactive components in Radix Rhizoma Salviae Miltiorrhizae by high-performance liquid chromatography with ultraviolet and mass spectrometric detection. Biomed. Chromatogr. 22 (2008) 164-172
    • (2008) Biomed. Chromatogr. , vol.22 , pp. 164-172
    • Cao, J.1    Wei, Y.J.2    Qi, L.W.3    Li, P.4    Qian, Z.M.5    Luo, H.W.6    Chen, J.7    Zhao, J.8
  • 4
    • 5444268663 scopus 로고    scopus 로고
    • Protective effects of danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction
    • Chan K., Chui S.H., Wong D.Y., Ha W.Y., Chan C.L., and Wong R.N. Protective effects of danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction. Life Sci. 75 (2004) 3157-3171
    • (2004) Life Sci. , vol.75 , pp. 3157-3171
    • Chan, K.1    Chui, S.H.2    Wong, D.Y.3    Ha, W.Y.4    Chan, C.L.5    Wong, R.N.6
  • 5
    • 16644375017 scopus 로고    scopus 로고
    • Comparison of the pharmacokinetics of hawthorm phenolics in extract versus individual pure compound
    • Chang Q., Zuo Z., Ho W.K., and Chow M.S. Comparison of the pharmacokinetics of hawthorm phenolics in extract versus individual pure compound. J. Clin. Pharmacol. 45 (2005) 106-112
    • (2005) J. Clin. Pharmacol. , vol.45 , pp. 106-112
    • Chang, Q.1    Zuo, Z.2    Ho, W.K.3    Chow, M.S.4
  • 6
    • 0033604485 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of effects of sodium caprate on enteral peptide absorption and on mucosal morphology
    • Chao A.C., Nguyen J.V., Broughall M., Griffin A., Fix J.A., and Daddona P.E. In vitro and in vivo evaluation of effects of sodium caprate on enteral peptide absorption and on mucosal morphology. Int. J. Pharm. 191 (1999) 15-24
    • (1999) Int. J. Pharm. , vol.191 , pp. 15-24
    • Chao, A.C.1    Nguyen, J.V.2    Broughall, M.3    Griffin, A.4    Fix, J.A.5    Daddona, P.E.6
  • 7
    • 0031780682 scopus 로고    scopus 로고
    • Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line: comparison with the parental Caco-2 cell line
    • Grès M.C., Julian B., Bourrié M., Meunier V., Roques C., Berger M., Boulenc X., Berger Y., and Fabre G. Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line: comparison with the parental Caco-2 cell line. Pharm. Res. 15 (1998) 726-733
    • (1998) Pharm. Res. , vol.15 , pp. 726-733
    • Grès, M.C.1    Julian, B.2    Bourrié, M.3    Meunier, V.4    Roques, C.5    Berger, M.6    Boulenc, X.7    Berger, Y.8    Fabre, G.9
  • 8
    • 19544382032 scopus 로고    scopus 로고
    • Clinical investigation of composite Danshen Dripping Pill for the treatment of angina pectoris
    • Guo Z.X., Jia W., Gao W.Y., Xu Z.H., Zhao L.B., and Xiao P.G. Clinical investigation of composite Danshen Dripping Pill for the treatment of angina pectoris. Zhongguo Tianran Yaowu 1 (2003) 124-128
    • (2003) Zhongguo Tianran Yaowu , vol.1 , pp. 124-128
    • Guo, Z.X.1    Jia, W.2    Gao, W.Y.3    Xu, Z.H.4    Zhao, L.B.5    Xiao, P.G.6
  • 9
    • 27844437437 scopus 로고    scopus 로고
    • Pharmacokinetics study of danshensu in compound Danshen Dripping Pill
    • Hong X., Mi S.Q., and Wang N.S. Pharmacokinetics study of danshensu in compound Danshen Dripping Pill. Zhongyao Xinyao yu Linchuang Yaoli 11 (2000) 286-288
    • (2000) Zhongyao Xinyao yu Linchuang Yaoli , vol.11 , pp. 286-288
    • Hong, X.1    Mi, S.Q.2    Wang, N.S.3
  • 10
    • 0037093722 scopus 로고    scopus 로고
    • Intestinal paracellular permeation enhancement with quaternised chitosan: in situ and in vitro evaluation
    • Jonker C., Hamman J.H., and Kotzé A.F. Intestinal paracellular permeation enhancement with quaternised chitosan: in situ and in vitro evaluation. Int. J. Pharm. 238 (2002) 205-213
    • (2002) Int. J. Pharm. , vol.238 , pp. 205-213
    • Jonker, C.1    Hamman, J.H.2    Kotzé, A.F.3
  • 11
    • 4043080670 scopus 로고    scopus 로고
    • Lithospermic acid B isolated from Salvia miltiorrhiza ameliorates ischemia/reperfusion-induced renal injury in rats
    • Kang D.G., Oh H., Sohn E.J., Hur T.Y., Lee K.C., Kim K.J., Kim T.Y., and Lee H.S. Lithospermic acid B isolated from Salvia miltiorrhiza ameliorates ischemia/reperfusion-induced renal injury in rats. Life Sci. 75 (2004) 1801-1816
    • (2004) Life Sci. , vol.75 , pp. 1801-1816
    • Kang, D.G.1    Oh, H.2    Sohn, E.J.3    Hur, T.Y.4    Lee, K.C.5    Kim, K.J.6    Kim, T.Y.7    Lee, H.S.8
  • 14
    • 4644325763 scopus 로고    scopus 로고
    • Inhibition of shear-induced platelet aggregation in rat by tetramethylpyrazine and salvianolic acid B
    • Li M., Zhao C., Wong R.N., Goto S., Wang Z.M., and Liao F.L. Inhibition of shear-induced platelet aggregation in rat by tetramethylpyrazine and salvianolic acid B. Clin. Hemorheol. Microcirc. 31 (2004) 97-103
    • (2004) Clin. Hemorheol. Microcirc. , vol.31 , pp. 97-103
    • Li, M.1    Zhao, C.2    Wong, R.N.3    Goto, S.4    Wang, Z.M.5    Liao, F.L.6
  • 15
    • 43049094104 scopus 로고    scopus 로고
    • Determination and pharmacokinetics of danshensu in rat plasma after oral administration of danshen extract using liquid chromatography/tandem mass spectrometry
    • Li W., Li Z.W., Han J.P., Li X.X., Gao J., and Liu C.X. Determination and pharmacokinetics of danshensu in rat plasma after oral administration of danshen extract using liquid chromatography/tandem mass spectrometry. Eur. J. Drug Metab. Pharmacokinet. 33 (2008) 9-16
    • (2008) Eur. J. Drug Metab. Pharmacokinet. , vol.33 , pp. 9-16
    • Li, W.1    Li, Z.W.2    Han, J.P.3    Li, X.X.4    Gao, J.5    Liu, C.X.6
  • 16
    • 33846422712 scopus 로고    scopus 로고
    • Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats
    • Li X., Yu C., Lu Y., Gu Y., Lu J., Xu W., Xuan L., and Wang Y. Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats. Drug Metab. Dispos. 35 (2007) 234-239
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 234-239
    • Li, X.1    Yu, C.2    Lu, Y.3    Gu, Y.4    Lu, J.5    Xu, W.6    Xuan, L.7    Wang, Y.8
  • 17
    • 0031978205 scopus 로고    scopus 로고
    • Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: assessment of molecular weight dependence and demonstration of transport routes
    • Lindmark T., Schipper N., Lazorová L., de Boer A.G., and Artursson P. Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: assessment of molecular weight dependence and demonstration of transport routes. J. Drug Target. 5 (1998) 215-223
    • (1998) J. Drug Target. , vol.5 , pp. 215-223
    • Lindmark, T.1    Schipper, N.2    Lazorová, L.3    de Boer, A.G.4    Artursson, P.5
  • 18
    • 34848828512 scopus 로고    scopus 로고
    • Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS)
    • Liu M., Li Y.G., Zhang F., Yang L., Chou G.X., Wang Z.T., and Hu Z.B. Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS). J. Sep. Sci. 30 (2007) 2256-2267
    • (2007) J. Sep. Sci. , vol.30 , pp. 2256-2267
    • Liu, M.1    Li, Y.G.2    Zhang, F.3    Yang, L.4    Chou, G.X.5    Wang, Z.T.6    Hu, Z.B.7
  • 19
    • 27844565133 scopus 로고    scopus 로고
    • Research advance of Fufang Danshen dosage forms
    • Liu X.Q., Luo X.T., and Ouyang X.A. Research advance of Fufang Danshen dosage forms. Shizhen Guoyi Guoyao 12 (2001) 474-475
    • (2001) Shizhen Guoyi Guoyao , vol.12 , pp. 474-475
    • Liu, X.Q.1    Luo, X.T.2    Ouyang, X.A.3
  • 20
    • 0035658854 scopus 로고    scopus 로고
    • Determination of danshensu, a major active compound of Radix Salvia miltiorrhiza in dog plasma by HPLC with fluorescence detection
    • Luo X.J., Bi K.S., Zhou S.Y., Wei Q.H., and Zhang R.H. Determination of danshensu, a major active compound of Radix Salvia miltiorrhiza in dog plasma by HPLC with fluorescence detection. Biomed. Chromatogr. 15 (2001) 493-496
    • (2001) Biomed. Chromatogr. , vol.15 , pp. 493-496
    • Luo, X.J.1    Bi, K.S.2    Zhou, S.Y.3    Wei, Q.H.4    Zhang, R.H.5
  • 21
    • 34547982438 scopus 로고    scopus 로고
    • Improved quality evaluation of Radix Salvia miltiorrhiza through simultaneous quantification of seven major active components by high-performance liquid chromatography and principal component analysis
    • Ma H.L., Qin M.J., Qi L.W., Wu G., and Shu P. Improved quality evaluation of Radix Salvia miltiorrhiza through simultaneous quantification of seven major active components by high-performance liquid chromatography and principal component analysis. Biomed. Chromatogr. 21 (2007) 931-939
    • (2007) Biomed. Chromatogr. , vol.21 , pp. 931-939
    • Ma, H.L.1    Qin, M.J.2    Qi, L.W.3    Wu, G.4    Shu, P.5
  • 22
    • 30844439844 scopus 로고    scopus 로고
    • Oral delivery of low-molecular-weight heparin using sodium caprate as absorption enhancer reaches therapeutic levels
    • Motlekar N.A., Srivenugopal K.S., Wachtel M.S., and Youan B.B. Oral delivery of low-molecular-weight heparin using sodium caprate as absorption enhancer reaches therapeutic levels. J. Drug Target. 13 (2005) 573-583
    • (2005) J. Drug Target. , vol.13 , pp. 573-583
    • Motlekar, N.A.1    Srivenugopal, K.S.2    Wachtel, M.S.3    Youan, B.B.4
  • 23
    • 0343237727 scopus 로고    scopus 로고
    • Effect of magnesium tanshinoate B on the production of nitric oxide in endothelial cells
    • O K., Cheung F., Sung F.L., Zhu D.Y., and Siow Y.L. Effect of magnesium tanshinoate B on the production of nitric oxide in endothelial cells. Mol. Cell Biochem. 207 (2000) 35-39
    • (2000) Mol. Cell Biochem. , vol.207 , pp. 35-39
    • O, K.1    Cheung, F.2    Sung, F.L.3    Zhu, D.Y.4    Siow, Y.L.5
  • 24
    • 0035846880 scopus 로고    scopus 로고
    • Magnesium tanshinoate B (MTB) inhibits low-density lipoprotein oxidation
    • O K., Lynn E.G., Vazhappilly R., Au-Yeung K.K., Zhu D.Y., and Siow Y.L. Magnesium tanshinoate B (MTB) inhibits low-density lipoprotein oxidation. Life Sci. 68 (2001) 903-912
    • (2001) Life Sci. , vol.68 , pp. 903-912
    • O, K.1    Lynn, E.G.2    Vazhappilly, R.3    Au-Yeung, K.K.4    Zhu, D.Y.5    Siow, Y.L.6
  • 25
    • 0035680844 scopus 로고    scopus 로고
    • Protective effects of Salvia miltiorrhiza on angiotensin II-induced hypertrophic responses in neonatal rat cardiac cells
    • Ouyang X.S., Takahashi K., Komatsu K., Nakamura N., Hattori M., Baba A., and Azuma J. Protective effects of Salvia miltiorrhiza on angiotensin II-induced hypertrophic responses in neonatal rat cardiac cells. Jpn. J. Pharmacol. 87 (2001) 289-296
    • (2001) Jpn. J. Pharmacol. , vol.87 , pp. 289-296
    • Ouyang, X.S.1    Takahashi, K.2    Komatsu, K.3    Nakamura, N.4    Hattori, M.5    Baba, A.6    Azuma, J.7
  • 26
    • 24644490565 scopus 로고    scopus 로고
    • Determination of danshensu in rat serum after oral administer compound Salvia Recipe
    • Pan G.X., Zhang B.L., and Gao X.M. Determination of danshensu in rat serum after oral administer compound Salvia Recipe. Zhongguo Zhongyao Zazhi 28 (2003) 562-565
    • (2003) Zhongguo Zhongyao Zazhi , vol.28 , pp. 562-565
    • Pan, G.X.1    Zhang, B.L.2    Gao, X.M.3
  • 27
    • 4143102478 scopus 로고    scopus 로고
    • Study of the determination and pharmacokinetics of compound Danshen Dripping Pill in human serum by column switching liquid chromatography electrospray ion trap mass spectrometry
    • Pei W.J., Zhao X.F., Zhu Z.M., Lin C.Z., and Zhao W.M. Study of the determination and pharmacokinetics of compound Danshen Dripping Pill in human serum by column switching liquid chromatography electrospray ion trap mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 809 (2004) 237-242
    • (2004) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.809 , pp. 237-242
    • Pei, W.J.1    Zhao, X.F.2    Zhu, Z.M.3    Lin, C.Z.4    Zhao, W.M.5
  • 28
    • 0030833787 scopus 로고    scopus 로고
    • Effects of absorption enhancers on the transport of model compounds in Caco-2 cell monolayers: assessment by confocal laser scanning microscopy
    • Sakai M., Imai T., Ohtake H., Azuma H., and Otagiri M. Effects of absorption enhancers on the transport of model compounds in Caco-2 cell monolayers: assessment by confocal laser scanning microscopy. J. Pharm. Sci. 86 (1997) 779-785
    • (1997) J. Pharm. Sci. , vol.86 , pp. 779-785
    • Sakai, M.1    Imai, T.2    Ohtake, H.3    Azuma, H.4    Otagiri, M.5
  • 29
    • 0025951357 scopus 로고
    • Role of paracellular pathway in nonelectrolyte permeation across rat colon epithelium enhanced by sodium caprate and sodium caprylate
    • Sawada T., Ogawa T., Tomita M., Hayashi M., and Awazu S. Role of paracellular pathway in nonelectrolyte permeation across rat colon epithelium enhanced by sodium caprate and sodium caprylate. Pharm. Res. 8 (1991) 1365-1371
    • (1991) Pharm. Res. , vol.8 , pp. 1365-1371
    • Sawada, T.1    Ogawa, T.2    Tomita, M.3    Hayashi, M.4    Awazu, S.5
  • 30
    • 0027942425 scopus 로고
    • Enhancement of intestinal insulin absorption by bile salt-fatty acid mixed micelles in dogs
    • Scott-Moncrieff J.C., Shao Z., and Mitra A.K. Enhancement of intestinal insulin absorption by bile salt-fatty acid mixed micelles in dogs. J. Pharm. Sci. 83 (1994) 1465-1469
    • (1994) J. Pharm. Sci. , vol.83 , pp. 1465-1469
    • Scott-Moncrieff, J.C.1    Shao, Z.2    Mitra, A.K.3
  • 31
    • 14644442887 scopus 로고    scopus 로고
    • Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC
    • Shi Z.H., He J.T., Yao T.T., Chang W.B., and Zhao M.P. Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC. J. Pharm. Biomed. Anal. 37 (2005) 481-486
    • (2005) J. Pharm. Biomed. Anal. , vol.37 , pp. 481-486
    • Shi, Z.H.1    He, J.T.2    Yao, T.T.3    Chang, W.B.4    Zhao, M.P.5
  • 32
    • 0027973670 scopus 로고
    • Decanoic acid induced enhancement of rectal absorption of hydrophilic compounds in rats
    • Takahashi K., Murakami T., Yumoto R., Hattori T., Higashi Y., and Yata N. Decanoic acid induced enhancement of rectal absorption of hydrophilic compounds in rats. Pharm. Res. 11 (1994) 1401-1404
    • (1994) Pharm. Res. , vol.11 , pp. 1401-1404
    • Takahashi, K.1    Murakami, T.2    Yumoto, R.3    Hattori, T.4    Higashi, Y.5    Yata, N.6
  • 33
    • 0031442625 scopus 로고    scopus 로고
    • Absorption of d-glucose in the rat studied using in situ intestinal perfusion: a permeability-index approach
    • Wang Y., Aun R., and Tse F.L. Absorption of d-glucose in the rat studied using in situ intestinal perfusion: a permeability-index approach. Pharm. Res. 14 (1997) 1563-1567
    • (1997) Pharm. Res. , vol.14 , pp. 1563-1567
    • Wang, Y.1    Aun, R.2    Tse, F.L.3
  • 34
    • 0034306505 scopus 로고    scopus 로고
    • Enhancing paracellular permeability by modulating epithelial tight junctions
    • Ward P.D., Tippin T.K., and Thakker D.R. Enhancing paracellular permeability by modulating epithelial tight junctions. Pharm. Sci. Technol. Today 3 (2000) 346-358
    • (2000) Pharm. Sci. Technol. Today , vol.3 , pp. 346-358
    • Ward, P.D.1    Tippin, T.K.2    Thakker, D.R.3
  • 35
    • 33846538002 scopus 로고    scopus 로고
    • Simultaneous determination of seven active components of Fufang Danshen Tablet by high performance liquid chromatography
    • Wei Y.J., Li S.L., and Li P. Simultaneous determination of seven active components of Fufang Danshen Tablet by high performance liquid chromatography. Biomed. Chromatogr. 21 (2007) 1-9
    • (2007) Biomed. Chromatogr. , vol.21 , pp. 1-9
    • Wei, Y.J.1    Li, S.L.2    Li, P.3
  • 36
    • 0031919197 scopus 로고    scopus 로고
    • Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol-fed rabbits by a water-soluble antioxidant-rich fraction of Salvia miltiorrhiza
    • Wu Y.J., Hong C.Y., Lin S.J., Wu P., and Shiao M.S. Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol-fed rabbits by a water-soluble antioxidant-rich fraction of Salvia miltiorrhiza. Arterioscler. Thromb. Vasc. Biol. 18 (1998) 481-486
    • (1998) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 481-486
    • Wu, Y.J.1    Hong, C.Y.2    Lin, S.J.3    Wu, P.4    Shiao, M.S.5
  • 37
    • 33750470777 scopus 로고    scopus 로고
    • Bioavailability of salvianolic acid B in conscious and freely moving rats
    • Wu Y.T., Chen Y.F., Hsieh Y.J., Jaw I., Shiao M.S., and Tsai T.H. Bioavailability of salvianolic acid B in conscious and freely moving rats. Int. J. Pharm. 326 (2006) 25-31
    • (2006) Int. J. Pharm. , vol.326 , pp. 25-31
    • Wu, Y.T.1    Chen, Y.F.2    Hsieh, Y.J.3    Jaw, I.4    Shiao, M.S.5    Tsai, T.H.6
  • 38
    • 34248393877 scopus 로고    scopus 로고
    • Determination of the main bioactive metabolites of Radix salvia miltiorrhizae in compound Danshen dripping pills and the tissue distribution of Danshensu in rabbit by SPE-HPLC-MSn
    • Xiaohui Z., Xinfeng Z., Xin Z., Shixiang W., Yinmao W., and Jianbin Z. Determination of the main bioactive metabolites of Radix salvia miltiorrhizae in compound Danshen dripping pills and the tissue distribution of Danshensu in rabbit by SPE-HPLC-MSn. J. Sep. Sci. 30 (2007) 851-857
    • (2007) J. Sep. Sci. , vol.30 , pp. 851-857
    • Xiaohui, Z.1    Xinfeng, Z.2    Xin, Z.3    Shixiang, W.4    Yinmao, W.5    Jianbin, Z.6
  • 39
    • 19644384525 scopus 로고    scopus 로고
    • Quantitative analysis of the marker compounds in Salvia miltiorrhiza root and its phytomedicinal preparations
    • Yuan D., Pan Y.N., Fu W.W., Makino T., and Kano Y. Quantitative analysis of the marker compounds in Salvia miltiorrhiza root and its phytomedicinal preparations. Chem. Pharm. Bull. 53 (2005) 508-514
    • (2005) Chem. Pharm. Bull. , vol.53 , pp. 508-514
    • Yuan, D.1    Pan, Y.N.2    Fu, W.W.3    Makino, T.4    Kano, Y.5
  • 40
    • 0036902502 scopus 로고    scopus 로고
    • Contents of four active components in different commercial crude drugs and preparations of Danshen (Salvia miltiorrhiza)
    • Zhang H., Yu C., Jia J.Y., Leung S., Siow Y.L., Man Y.K., and Zhu D.Y. Contents of four active components in different commercial crude drugs and preparations of Danshen (Salvia miltiorrhiza). Zhongguo Xinyao Zazhi 23 (2002) 1163-1168
    • (2002) Zhongguo Xinyao Zazhi , vol.23 , pp. 1163-1168
    • Zhang, H.1    Yu, C.2    Jia, J.Y.3    Leung, S.4    Siow, Y.L.5    Man, Y.K.6    Zhu, D.Y.7
  • 41
    • 14544273677 scopus 로고    scopus 로고
    • HPLC determination and pharmacokinetic studies of salvianolic acid B in rat plasma after oral administration of Radix Salvia Miltiorrhizae extract
    • Zhang J., Yu H., Sheng Y., Li L., Ye M., and Guo D. HPLC determination and pharmacokinetic studies of salvianolic acid B in rat plasma after oral administration of Radix Salvia Miltiorrhizae extract. Biomed. Chromatogr. 19 (2005) 15-18
    • (2005) Biomed. Chromatogr. , vol.19 , pp. 15-18
    • Zhang, J.1    Yu, H.2    Sheng, Y.3    Li, L.4    Ye, M.5    Guo, D.6
  • 42
    • 23744497186 scopus 로고    scopus 로고
    • Role of intestinal first-pass metabolism of baicalein in its absorption process
    • Zhang L., Lin G., Chang Q., and Zuo Z. Role of intestinal first-pass metabolism of baicalein in its absorption process. Pharm. Res. 22 (2005) 1050-1058
    • (2005) Pharm. Res. , vol.22 , pp. 1050-1058
    • Zhang, L.1    Lin, G.2    Chang, Q.3    Zuo, Z.4
  • 43
    • 8444230840 scopus 로고    scopus 로고
    • Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model
    • Zhang L., Zheng Y., Chow M.S., and Zuo Z. Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. Int. J. Pharm. 287 (2004) 1-12
    • (2004) Int. J. Pharm. , vol.287 , pp. 1-12
    • Zhang, L.1    Zheng, Y.2    Chow, M.S.3    Zuo, Z.4
  • 44
    • 1542344491 scopus 로고    scopus 로고
    • Extremely low bioavailability of magnesium lithospermate B, an active components from Salvia miltiorrhiza in rat
    • Zhang Y., Akao T., Nakamura N., Duan C.L., Hattori M., Yang X.W., and Liu J.X. Extremely low bioavailability of magnesium lithospermate B, an active components from Salvia miltiorrhiza in rat. Planta Med. 70 (2004) 138-142
    • (2004) Planta Med. , vol.70 , pp. 138-142
    • Zhang, Y.1    Akao, T.2    Nakamura, N.3    Duan, C.L.4    Hattori, M.5    Yang, X.W.6    Liu, J.X.7
  • 45
    • 3042634920 scopus 로고    scopus 로고
    • Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants
    • Zhang Y., Akao T., Nakamura N., Hattori M., Yang X.W., Duan C.L., and Liu J.X. Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants. Drug Metab. Dispos. 32 (2004) 752-757
    • (2004) Drug Metab. Dispos. , vol.32 , pp. 752-757
    • Zhang, Y.1    Akao, T.2    Nakamura, N.3    Hattori, M.4    Yang, X.W.5    Duan, C.L.6    Liu, J.X.7
  • 46
    • 0029829044 scopus 로고    scopus 로고
    • Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury
    • Zhao B.L., Jiang W., Zhao Y., Hou J.W., and Xin W.J. Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury. Biochem. Mol. Biol. Int. 38 (1996) 1171-1182
    • (1996) Biochem. Mol. Biol. Int. , vol.38 , pp. 1171-1182
    • Zhao, B.L.1    Jiang, W.2    Zhao, Y.3    Hou, J.W.4    Xin, W.J.5
  • 47
    • 33646417027 scopus 로고    scopus 로고
    • Improved quality control method for Danshen products-consideration of both hydrophilic and lipophilic active components
    • Zhou L., Chow M., and Zuo Z. Improved quality control method for Danshen products-consideration of both hydrophilic and lipophilic active components. J. Pharm. Biomed. Anal. 41 (2006) 744-750
    • (2006) J. Pharm. Biomed. Anal. , vol.41 , pp. 744-750
    • Zhou, L.1    Chow, M.2    Zuo, Z.3
  • 48
    • 27844511101 scopus 로고    scopus 로고
    • Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
    • Zhou L., Zuo Z., and Chow M.S. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol. 45 (2005) 1345-1359
    • (2005) J. Clin. Pharmacol. , vol.45 , pp. 1345-1359
    • Zhou, L.1    Zuo, Z.2    Chow, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.