-
1
-
-
33644768012
-
Kinase inhibitors and airway inflammation
-
Adcock, I.M., Chung, K.F., Caramori, G. and Ito, K. (2006) Kinase inhibitors and airway inflammation. Eur J Pharmacol 533: 118-132.
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 118-132
-
-
Adcock, I.M.1
Chung, K.F.2
Caramori, G.3
Ito, K.4
-
2
-
-
33747595955
-
Transcription factors in airway diseases
-
Barnes, P.J. (2006) Transcription factors in airway diseases. Lab Invest 86: 867-872.
-
(2006)
Lab Invest
, vol.86
, pp. 867-872
-
-
Barnes, P.J.1
-
3
-
-
4444280869
-
Prospects for new drugs for chronic obstructive pulmonary disease
-
Barnes, P.J. and Hansel, T.T. (2004) Prospects for new drugs for chronic obstructive pulmonary disease. Lancet 364: 985-996.
-
(2004)
Lancet
, vol.364
, pp. 985-996
-
-
Barnes, P.J.1
Hansel, T.T.2
-
4
-
-
0024996333
-
Small airway dimensions in smokers with obstruction to airflow
-
Bosken, C.H., Wiggs, B.R., Paré, P.D., Hogg, J.C. (1990) Small airway dimensions in smokers with obstruction to airflow. Am Rev Respir Dis 142: 563-570.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 563-570
-
-
Bosken, C.H.1
Wiggs, B.R.2
Paré, P.D.3
Hogg, J.C.4
-
5
-
-
33745368689
-
Evidence of angiogenesis in bronchial biopsies of smokers with and without airway obstruction
-
Calabrese, C., Bocchino, V., Vatrella, A., Marzo, C., Guarino, C., Mascitti, S. et al. (2006) Evidence of angiogenesis in bronchial biopsies of smokers with and without airway obstruction. Resp Med 100: 1415-1422.
-
(2006)
Resp Med
, vol.100
, pp. 1415-1422
-
-
Calabrese, C.1
Bocchino, V.2
Vatrella, A.3
Marzo, C.4
Guarino, C.5
Mascitti, S.6
-
6
-
-
0037425745
-
TRial of Inhaled STeroids ANd long-acting beta2 agonists study group. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial
-
Calverley, P., Pauwels, R., Vestbo, J., Jones, P., Pride, N., Gulsvik, A. et al. (2003) TRial of Inhaled STeroids ANd long-acting beta2 agonists study group. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 361: 449-456.
-
(2003)
Lancet
, vol.361
, pp. 449-456
-
-
Calverley, P.1
Pauwels, R.2
Vestbo, J.3
Jones, P.4
Pride, N.5
Gulsvik, A.6
-
7
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet, P. (2003) Angiogenesis in health and disease. Nat Med 9: 653-660.
-
(2003)
Nat Med
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
8
-
-
4344689086
-
The transforming growth factor-beta1 gene is associated with chronic obstructive pulmonary disease
-
Celedòn, J.C., Lange, C., Raby, B.A., Litonjua, A.A., Palmer, L.J., DeMeo, D.L. et al. (2004) The transforming growth factor-beta1 gene is associated with chronic obstructive pulmonary disease. Hum Mol Genet 13: 1649-1656.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1649-1656
-
-
Celedòn, J.C.1
Lange, C.2
Raby, B.A.3
Litonjua, A.A.4
Palmer, L.J.5
DeMeo, D.L.6
-
9
-
-
33947646770
-
Vascular remodelling and angiogenesis in asthma: morphological aspects and pharmacological modulation
-
Chetta, A., Zanini, A., Torre, O. and Olivieri, D. (2007) Vascular remodelling and angiogenesis in asthma: morphological aspects and pharmacological modulation. Inflamm Allergy Drug Targets 1: 41-45.
-
(2007)
Inflamm Allergy Drug Targets
, vol.1
, pp. 41-45
-
-
Chetta, A.1
Zanini, A.2
Torre, O.3
Olivieri, D.4
-
10
-
-
0037365622
-
Vascular component of airway remodelling in asthma is reduced by high dose of fluticasone
-
Chetta, A., Zanini, A., Foresi, A., Del Donno, M., Castagnaro, A., D'Ippolito, R. et al. (2003) Vascular component of airway remodelling in asthma is reduced by high dose of fluticasone. Am J Respir Crit Care Med 167: 751-757.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 751-757
-
-
Chetta, A.1
Zanini, A.2
Foresi, A.3
Del Donno, M.4
Castagnaro, A.5
D'Ippolito, R.6
-
11
-
-
34547815598
-
Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs
-
Churg, A., Wang, R., Wang, X., Onnervik, P.O., Thim, K. and Wright, J.L. (2007) Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs. Thorax 62: 706-713.
-
(2007)
Thorax
, vol.62
, pp. 706-713
-
-
Churg, A.1
Wang, R.2
Wang, X.3
Onnervik, P.O.4
Thim, K.5
Wright, J.L.6
-
12
-
-
34447130180
-
FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastic recurrent nonsquamous non-small cell lung cancer
-
Cohen, M.H., Gootenberg, J., Keegan, P., Pazdur, R. (2007) FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastic recurrent nonsquamous non-small cell lung cancer. Oncologist 12: 713-718.
-
(2007)
Oncologist
, vol.12
, pp. 713-718
-
-
Cohen, M.H.1
Gootenberg, J.2
Keegan, P.3
Pazdur, R.4
-
13
-
-
18744384999
-
Therapeutic inhibition of matrix metalloproteinases for the treatment of chronic pulmonary disease (COPD)
-
Daheshia, M. (2005) Therapeutic inhibition of matrix metalloproteinases for the treatment of chronic pulmonary disease (COPD). Curr Med Res Opin 21: 587-594.
-
(2005)
Curr Med Res Opin
, vol.21
, pp. 587-594
-
-
Daheshia, M.1
-
14
-
-
34147093566
-
Molecular mechanisms in chronic obstructive pulmonary disease: potential targets for therapy
-
de Boer, W.I., Alagappan, V.K.T. and Sharma, H.S. (2007) Molecular mechanisms in chronic obstructive pulmonary disease: potential targets for therapy. Cell Biochem Biophys 47: 131-148.
-
(2007)
Cell Biochem Biophys
, vol.47
, pp. 131-148
-
-
de Boer, W.I.1
Alagappan, V.K.T.2
Sharma, H.S.3
-
15
-
-
0032416948
-
Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease
-
de Boer, W.I., van Schadewijk, A., Sont, J.K., Sharma, H.S., Stolk, J., Hiemstra, P.S. and van Krieken, J.H. (1998) Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 158: 1951-1957.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1951-1957
-
-
de Boer, W.I.1
van Schadewijk, A.2
Sont, J.K.3
Sharma, H.S.4
Stolk, J.5
Hiemstra, P.S.6
van Krieken, J.H.7
-
16
-
-
84975525035
-
Clinical applications of research on angiogenesis
-
Folkman, J. (1995) Clinical applications of research on angiogenesis. New Engl J Med 333: 1757-1763.
-
(1995)
New Engl J Med
, vol.333
, pp. 1757-1763
-
-
Folkman, J.1
-
17
-
-
0032557564
-
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
-
Gerber, H.P., Dixit, V. and Ferrara, N. (1998) Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 273: 13313-13316.
-
(1998)
J Biol Chem
, vol.273
, pp. 13313-13316
-
-
Gerber, H.P.1
Dixit, V.2
Ferrara, N.3
-
18
-
-
0037332084
-
Neovastat-a novel antiangiogenic drug for cancer therapy
-
Gingras, D., Boivin, D., Deckers, C., Gendron, S., Barthomeuf, C. and Béliveau, R. (2003) Neovastat-a novel antiangiogenic drug for cancer therapy. Anticancer Drugs 14: 91-96.
-
(2003)
Anticancer Drugs
, vol.14
, pp. 91-96
-
-
Gingras, D.1
Boivin, D.2
Deckers, C.3
Gendron, S.4
Barthomeuf, C.5
Béliveau, R.6
-
19
-
-
0345688717
-
Airway microvascular extravasation and luminal entry of plasma
-
Greiff, L., Andersson, M., Erjefålt, J.S., Persson, C.G. and Wollmer, P. (2003) Airway microvascular extravasation and luminal entry of plasma. Clin Physiol Funct Imaging 23: 301-306.
-
(2003)
Clin Physiol Funct Imaging
, vol.23
, pp. 301-306
-
-
Greiff, L.1
Andersson, M.2
Erjefålt, J.S.3
Persson, C.G.4
Wollmer, P.5
-
20
-
-
33847022313
-
Sorafenib and Sunitinib in the treatment of advanced non-small cell lung cancer
-
Gridelli, C., Maione, P., Del Gaizo, F., Colantuoni, G., Guerriero, C., Ferrara, C. et al. (2007) Sorafenib and Sunitinib in the treatment of advanced non-small cell lung cancer. Oncologist 12: 191-200.
-
(2007)
Oncologist
, vol.12
, pp. 191-200
-
-
Gridelli, C.1
Maione, P.2
Del Gaizo, F.3
Colantuoni, G.4
Guerriero, C.5
Ferrara, C.6
-
21
-
-
15844401603
-
Quantitative analysis of bronchial wall vascularity in the medium and small airways of patients with asthma and COPD
-
Hashimoto, M., Tanaka, H. and Abe, S. (2005) Quantitative analysis of bronchial wall vascularity in the medium and small airways of patients with asthma and COPD. Chest 127: 965-972.
-
(2005)
Chest
, vol.127
, pp. 965-972
-
-
Hashimoto, M.1
Tanaka, H.2
Abe, S.3
-
22
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg, J.C., Chu, F., Utokaparch, S., Woods, R., Elliott, W.M., Buzatu, L. et al. (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350: 2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
-
23
-
-
30744443041
-
Inhaled corticosteroids: effects on the airway vasculature in bronchial asthma
-
Horvath, G. and Wanner, A. (2006) Inhaled corticosteroids: effects on the airway vasculature in bronchial asthma. Eur Respir J 27: 172-187.
-
(2006)
Eur Respir J
, vol.27
, pp. 172-187
-
-
Horvath, G.1
Wanner, A.2
-
24
-
-
0034846870
-
Inhaled corticosteroids decrease vascularity of the bronchial mucosa in patients with asthma
-
Hoshino, M., Takahashi, M., Takai, Y., Sim, J. and Aoike, N. (2001) Inhaled corticosteroids decrease vascularity of the bronchial mucosa in patients with asthma. Clin Exp Allergy 31: 722-730.
-
(2001)
Clin Exp Allergy
, vol.31
, pp. 722-730
-
-
Hoshino, M.1
Takahashi, M.2
Takai, Y.3
Sim, J.4
Aoike, N.5
-
25
-
-
2442700619
-
Endoglin regulates nitric oxide-dependent vasodilatation
-
Jerkic, M., Rivas-Elena, J.V., Prieto, M., Carròn, R., Sanz-Rodriguez, F., Pérez-Barriocanal, F. et al. (2004) Endoglin regulates nitric oxide-dependent vasodilatation. Faseb J 18: 609-611.
-
(2004)
Faseb J
, vol.18
, pp. 609-611
-
-
Jerkic, M.1
Rivas-Elena, J.V.2
Prieto, M.3
Carròn, R.4
Sanz-Rodriguez, F.5
Pérez-Barriocanal, F.6
-
26
-
-
36148988400
-
Role of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease
-
Kanazawa, H. (2007) Role of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease. Med Sci Monit 13: RA189-195.
-
(2007)
Med Sci Monit
, vol.13
, pp. RA189-RA195
-
-
Kanazawa, H.1
-
27
-
-
0037398983
-
Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease
-
Kanazawa, H., Asai, K., Hirata, K. and Yoshikawa, J. (2003) Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease. Am J Med 114: 354-358.
-
(2003)
Am J Med
, vol.114
, pp. 354-358
-
-
Kanazawa, H.1
Asai, K.2
Hirata, K.3
Yoshikawa, J.4
-
28
-
-
33750717856
-
(2006) Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease
-
et al
-
Kranenburg, A.R., Willems-Widyastuti, A., Mooi, W.J., Sterk, P.J., Alagappan, V.K.T., de Boer, W.I. et al. (2006) Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease. Am J Clin Pathol 126: 725-735.
-
Am J Clin Pathol
, vol.126
, pp. 725-735
-
-
Kranenburg, A.R.1
Willems-Widyastuti, A.2
Mooi, W.J.3
Sterk, P.J.4
Alagappan, V.K.T.5
de Boer, W.I.6
-
29
-
-
13544275539
-
Enhanced bronchial expression of vascular endothelial growth factor and receptors (Flk-1 and Flt-1) in patients with chronic obstructive pulmonary disease
-
Kranenburg, A.R., de Boer, W.I., Alagappan, V.K.T., Sterk, P.J. and Sharma, H.S. (2005) Enhanced bronchial expression of vascular endothelial growth factor and receptors (Flk-1 and Flt-1) in patients with chronic obstructive pulmonary disease. Thorax 60: 106-113.
-
(2005)
Thorax
, vol.60
, pp. 106-113
-
-
Kranenburg, A.R.1
de Boer, W.I.2
Alagappan, V.K.T.3
Sterk, P.J.4
Sharma, H.S.5
-
30
-
-
18144406878
-
Chronic obstructive pulmonary disease is associated with enhanced expression of FGF-1, FGF-2 and FGFR-1
-
Kranenburg, A.R., Willems-Widyastuti, A., Mooi, W.J., Saxena, P.R., Sterk, P.J., de Boer, W.I. and Sharma, H.S. (2005) Chronic obstructive pulmonary disease is associated with enhanced expression of FGF-1, FGF-2 and FGFR-1. J Pathol 206: 28-38.
-
(2005)
J Pathol
, vol.206
, pp. 28-38
-
-
Kranenburg, A.R.1
Willems-Widyastuti, A.2
Mooi, W.J.3
Saxena, P.R.4
Sterk, P.J.5
de Boer, W.I.6
Sharma, H.S.7
-
31
-
-
0027365905
-
Small airways dimensions in asthma and chronic obstructive pulmonary disease
-
Kuwano, K., Bosken, C.H., Paré, P.D., Bai, T.R., Wiggs, B.R. and Hogg, J.C. (1993) Small airways dimensions in asthma and chronic obstructive pulmonary disease. Am Rev Respir Dis 148: 1220-1225.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1220-1225
-
-
Kuwano, K.1
Bosken, C.H.2
Paré, P.D.3
Bai, T.R.4
Wiggs, B.R.5
Hogg, J.C.6
-
32
-
-
0036242810
-
SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice
-
Laird, A.D., Christensen, J.G., Li, G., Carver, J., Smith, K., Xin, X. et al. (2002) SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice. FASEB J 16: 681-690.
-
(2002)
FASEB J
, vol.16
, pp. 681-690
-
-
Laird, A.D.1
Christensen, J.G.2
Li, G.3
Carver, J.4
Smith, K.5
Xin, X.6
-
33
-
-
8144230707
-
Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction
-
Lebrin, F., Goumans, M.J., Jonker, L., Carvalho, R.L.C., Valdimarsdottir, G., Thorikay, M. et al. (2004) Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction. Embo J 23: 4018-4028.
-
(2004)
Embo J
, vol.23
, pp. 4018-4028
-
-
Lebrin, F.1
Goumans, M.J.2
Jonker, L.3
Carvalho, R.L.C.4
Valdimarsdottir, G.5
Thorikay, M.6
-
34
-
-
35548940240
-
Neovastat (AE-941) inhibits the airway inflammation via VEGF and HIF-2alpha suppression
-
Lee, S.Y. and Chung, S.M. (2007) Neovastat (AE-941) inhibits the airway inflammation via VEGF and HIF-2alpha suppression. Vascul Pharmacol 47: 313-318.
-
(2007)
Vascul Pharmacol
, vol.47
, pp. 313-318
-
-
Lee, S.Y.1
Chung, S.M.2
-
35
-
-
34748863572
-
Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis
-
Mahabeleshwar, G.H., Feng, W., Reddy, K., Plow, E.F. and Byzova, T.V. (2007) Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis. Circ Res 101: 570-580.
-
(2007)
Circ Res
, vol.101
, pp. 570-580
-
-
Mahabeleshwar, G.H.1
Feng, W.2
Reddy, K.3
Plow, E.F.4
Byzova, T.V.5
-
36
-
-
2442528995
-
Effect of montelukast and fluticasone propionate on airway mucosal blood flow in asthma
-
Mendes, E.S., Campos, M.A., Hurtado, A. and Wanner, A. (2004) Effect of montelukast and fluticasone propionate on airway mucosal blood flow in asthma. Am J Respir Crit Care Med 169: 1131-1134.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 1131-1134
-
-
Mendes, E.S.1
Campos, M.A.2
Hurtado, A.3
Wanner, A.4
-
37
-
-
34247222126
-
Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors
-
Newton, R., Holden, N.S., Catley, M.C., Oyelusi, W., Leigh, R., Proud, D. et al. (2007) Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors. J Pharmacol Exp Ther 321: 734-742.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 734-742
-
-
Newton, R.1
Holden, N.S.2
Catley, M.C.3
Oyelusi, W.4
Leigh, R.5
Proud, D.6
-
38
-
-
0035402361
-
Effect of a long-acting β2-agonist over three months on airway wall vascular remodeling in asthma
-
Orsida, B.E., Ward, C., Li, X., Bish, R., Wilson, J.W., Thien, F. et al. (2001) Effect of a long-acting β2-agonist over three months on airway wall vascular remodeling in asthma. Am J Respir Crit Care Med 164: 117-121.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 117-121
-
-
Orsida, B.E.1
Ward, C.2
Li, X.3
Bish, R.4
Wilson, J.W.5
Thien, F.6
-
39
-
-
0033024225
-
Vascularity in asthmatic airways: relation to inhaled steroid dose
-
Orsida, B.E., Li, X., Hickey, B., Thien, F., Wilson, J.W. and Walters, E.H. (1999) Vascularity in asthmatic airways: relation to inhaled steroid dose. Thorax 54: 289-295.
-
(1999)
Thorax
, vol.54
, pp. 289-295
-
-
Orsida, B.E.1
Li, X.2
Hickey, B.3
Thien, F.4
Wilson, J.W.5
Walters, E.H.6
-
40
-
-
0035035768
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary
-
Pauwels, R.A., Buist, A.S., Calverley, P.M., Jenkins, C.R. and Hurd, S.S. (2001) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary. Am J Respir Crit Care Med 163: 1256-1276.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1256-1276
-
-
Pauwels, R.A.1
Buist, A.S.2
Calverley, P.M.3
Jenkins, C.R.4
Hurd, S.S.5
-
41
-
-
44649153952
-
Increased activation of p38 MAPK in COPD
-
Renda, T., Baraldo, S., Pelaia, G., Bazzan, E., Turato, G., Papi, A. et al. (2008) Increased activation of p38 MAPK in COPD. Eur Respir J 31: 62-69.
-
(2008)
Eur Respir J
, vol.31
, pp. 62-69
-
-
Renda, T.1
Baraldo, S.2
Pelaia, G.3
Bazzan, E.4
Turato, G.5
Papi, A.6
-
42
-
-
34547657584
-
Vascular endothelial growth factor trap in non-small cell lung cancer
-
Riely, G.J. and Miller, V.A. (2007) Vascular endothelial growth factor trap in non-small cell lung cancer. Clin Cancer Res 13: 4623s-4627s.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4623s-4627s
-
-
Riely, G.J.1
Miller, V.A.2
-
44
-
-
0034988161
-
Cellular and structural changes of chronic obstructive pulmonary disease
-
Saetta, M., Turato, G., Maestrelli, P., Mapp, C.E. and Fabbri, L.M. (2001) Cellular and structural changes of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 163: 1304-1309.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1304-1309
-
-
Saetta, M.1
Turato, G.2
Maestrelli, P.3
Mapp, C.E.4
Fabbri, L.M.5
-
45
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler, A., Gray, R., Perry, M.C., Brahmer, J., Schiller, J.H., Dowlati, A. et al. (2006) Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 55: 2542-2550.
-
(2006)
N Engl J Med
, vol.55
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
-
46
-
-
30544448281
-
Phase I clinical and pharmacological evaluation of the multi-tyrosine kinase inhibitor SU006668 by chronic oral dosing
-
Sessa, C., Viganò, L., Grasselli, G., Trigo, J., Marimon, I., Lladò, A. et al. (2006) Phase I clinical and pharmacological evaluation of the multi-tyrosine kinase inhibitor SU006668 by chronic oral dosing. Eur J Cancer 42: 171-178.
-
(2006)
Eur J Cancer
, vol.42
, pp. 171-178
-
-
Sessa, C.1
Viganò, L.2
Grasselli, G.3
Trigo, J.4
Marimon, I.5
Lladò, A.6
-
47
-
-
0033558087
-
Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2
-
Soldi, R., Mitola, S., Strasly, M., Defilippi, P., Tarone, G. and Bussolino, F. (1999) Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. EMBO J 18: 882-892.
-
(1999)
EMBO J
, vol.18
, pp. 882-892
-
-
Soldi, R.1
Mitola, S.2
Strasly, M.3
Defilippi, P.4
Tarone, G.5
Bussolino, F.6
-
48
-
-
2942729608
-
Management of chronic obstructive pulmonary disease
-
Sutherland, E.R. and Cherniack, R.M. (2004) Management of chronic obstructive pulmonary disease. N Engl J Med 350: 2689-2697.
-
(2004)
N Engl J Med
, vol.350
, pp. 2689-2697
-
-
Sutherland, E.R.1
Cherniack, R.M.2
-
49
-
-
17044453955
-
Increased expression of transforming growth factor-beta1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease
-
Takizawa, H., Tanaka, M., Takami, K., Ohtoshi, T., Ito, K., Satoh, M. et al. (2001) Increased expression of transforming growth factor-beta1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 163: 1476-1483.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1476-1483
-
-
Takizawa, H.1
Tanaka, M.2
Takami, K.3
Ohtoshi, T.4
Ito, K.5
Satoh, M.6
-
50
-
-
0347992806
-
Increased airway vascularity in newly diagnosed asthma using a high-magnification bronchovideoscope
-
Tanaka, H., Yamada, G., Saikai, T., Hashimoto, M., Tanaka, S., Suzuki, K. et al. (2003) Increased airway vascularity in newly diagnosed asthma using a high-magnification bronchovideoscope. Am J Respir Crit Care Med 168: 1495-1499.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1495-1499
-
-
Tanaka, H.1
Yamada, G.2
Saikai, T.3
Hashimoto, M.4
Tanaka, S.5
Suzuki, K.6
-
51
-
-
42349114587
-
Endothelial sprouting and angiogenesis: metalloproteinases in the lead
-
(Epub ahead of print)
-
van Hinsbergh,V.W. and Koolwijk, P. (2008) Endothelial sprouting and angiogenesis: metalloproteinases in the lead. Cardiovasc Res (Epub ahead of print).
-
(2008)
Cardiovasc Res
-
-
van HinsberghV.W.1
Koolwijk, P.2
-
52
-
-
10444274041
-
Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD
-
Vernooy, J.H., Lindeman, J.H., Jacobs, J.A., Hanemaaijer, R. and Wouters, E.F. et al. (2004) Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD. Chest 126: 1802-1810.
-
(2004)
Chest
, vol.126
, pp. 1802-1810
-
-
Vernooy, J.H.1
Lindeman, J.H.2
Jacobs, J.A.3
Hanemaaijer, R.4
Wouters, E.F.5
-
53
-
-
68749096849
-
-
Vignola, A.M., Paganin, F., Capieu, L., Scichilone, N., Bellia, M., Maakel, L. et al. (2004) Airway remodelling assessed by sputum
-
(2004)
Airway remodelling assessed by sputum
-
-
Vignola, A.M.1
Paganin, F.2
Capieu, L.3
Scichilone, N.4
Bellia, M.5
Maakel, L.6
-
54
-
-
10444273257
-
and high-resolution computed tomography in asthma and COPD
-
and high-resolution computed tomography in asthma and COPD. Eur Respir J 24: 910-917.
-
Eur Respir J
, vol.24
, pp. 910-917
-
-
-
55
-
-
0027563926
-
New perspectives on basic mechanisms in lung disease. Why are the airways so vascular?
-
Widdicombe, J. (1993) New perspectives on basic mechanisms in lung disease. Why are the airways so vascular? Thorax 48: 290-295.
-
(1993)
Thorax
, vol.48
, pp. 290-295
-
-
Widdicombe, J.1
-
57
-
-
0036087521
-
Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects
-
Yang,Y.A., Dukhanina, O., Tang, B., Mamura, M., Letterio, J.J., MacGregor, J. et al. (2002) Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects. J Clin Invest 109: 1607-1615.
-
(2002)
J Clin Invest
, vol.109
, pp. 1607-1615
-
-
YangY.A.1
Dukhanina, O.2
Tang, B.3
Mamura, M.4
Letterio, J.J.5
MacGregor, J.6
-
58
-
-
84992776439
-
Vascular remodeling and inhaled beclomethasone dipropionate in copd
-
D’, Ippolito R., Neri M., ERS Annual Congress, 598s
-
Zanini, A., Chetta, A., Nicolini, G., Castagnetti, C., D’ Ippolito, R., Neri, M. et al. (2007) Vascular remodeling and inhaled beclomethasone dipropionate in copd. ERS Annual Congress 598s.
-
(2007)
-
-
Zanini, A.1
Chetta, A.2
Nicolini, G.3
Castagnetti, C.4
|