Signaling proteins that regulate NaCL chemotaxis responses modulate longevity in C. elegans

Annals of the New York Academy of Sciences

Volumn 1170, Issue , 2009, Pages 682-687

  Lans, Hannes ^a   Dekkers, Martijn P J ^a   Hukema, Renate K ^a   Bialas, Nathan J ^b   Leroux, Michel R ^b   Jansen, Gert ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Aging; C. elegans; G proteins; Longevity; Sensory signaling

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; SODIUM CHLORIDE; SOMATOMEDIN;

AGING; BEHAVIOR; CAENORHABDITIS ELEGANS; CHEMOTAXIS; CONFERENCE PAPER; GENE MUTATION; GENETIC ANALYSIS; GENETICS; GENOME; INSULIN LIKE ACTIVITY; LIFESPAN; LONGEVITY; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; REGULATORY MECHANISM; SENSORY NERVE CONDUCTION; SIGNAL TRANSDUCTION; TASTE;

CAENORHABDITIS ELEGANS;

EID: 68649118866     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04362.x     Document Type: Conference Paper

References (25)

1. Hamm, H.E. 1998. The many faces of G protein signaling. J. Biol. Chem. 273: 669-672.
2. Neves, S.R., P. T. Ram & R. Iyengar. 2002.Gprotein pathways. Science 296: 1636-1639.
3. Jansen, G., D. Weinkove & R.H. Plasterk. 2002. The G-protein gamma subunit gpc-1 of the nematode C. elegans is involved in taste adaptation. EMBO J. 21:986-994.
4. Cuppen, E. et al. 2003. Proteins interacting with Caenorhabditis elegans Gα subunits. Comp. Funct. Genom. 4: 479-491.
5. Bastiani, C. & J. Mendel. 2006. Heterotrimeric G proteins in C. elegans (October 13, 2006). WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.75.1, http://www.wormbook.org.
6. Jansen, G. et al. 1999. The complete family of genes encoding G proteins of Caenorhabditis elegans. Nat. Genet. 21: 414-419.
7. Bargmann, C.I. 2006. Chemosensation in C. elegans (October 25, 2006). WormBook, ed. The C. elegans Research Community, Worm-Book, doi 10.1895/wormbook.1.123.1/, http://www.wormbook.org.
8. Chao, M.Y. et al. 2004. Feeding status and serotonin rapidly and reversiblymodulate a Caenorhabditis elegans chemosensory circuit. Proc. Natl. Acad. Sci. USA 101:15512-15517.
9. Hilliard, M.A. et al. 2004. Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans. EMBO J. 23:1101-1111.
10. Hukema, R.K. et al. 2006. Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans. EMBO J. 25: 312-322.
11. Lans, H., S. Rademakers & G. Jansen. 2004. A network of stimulatory and inhibitory Gα-subunits regulates olfaction in Caenorhabditis elegans. Genetics 167:1677-1687.
12. Roayaie, K. et al. 1998. The G alpha protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons. Neuron 20: 55-67.
13. Apfeld, J. & C. Kenyon. 1999. Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402: 804-809.
14. Alcedo, J. & C.Kenyon. 2004.Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 41: 45-55.
15. Libert, S. 2007. Regulation of Drosophila life span by olfaction and food-derived odors. Science 315: 1133-1137.
16. Kenyon, C. 2005. The plasticity of aging: Insights from long-lived mutants. Cell 120: 449-460.
17. Lans, H. & G. Jansen. 2007. Multiple sensory G proteins in the olfactory, gustatory and nociceptive neurons modulate longevity in Caenorhabditis elegans. Dev. Biol. 303: 474-482.
18. Murakami, H. & S. Murakami. 2007. Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity. Aging Cell 6: 483-488.
19. Ward, S. 1973. Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants. Proc. Natl. Acad. Sci. USA 70: 817-821.
20. Dusenbery, D.B. 1974. Analysis of chemotaxis in the nematode Caenorhabditis elegans by countercurrent separation. J. Exp. Zool. 188: 41-47.
21. Culotti, J.G. & R.L. Russell. 1978. Osmotic avoidance defectivemutants of the nematode Caenorhabditis elegans. Genetics 90: 243-256.
22. Bargmann, C.I. & H.R. Horvitz. 1991. Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans. Neuron 7: 729-742.
23. Hukema, R.K., S. Rademakers & G. Jansen. 2008. Gustatory plasticity in C. elegans involves integration of negative cues and NaCl taste mediated by serotonin, dopamine, and glutamate. Learn. Mem. 15:829-836.
24. Pinkston-Gosse, J. & C. Kenyon. 2007. DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans. Nat. Genet. 39: 1403-1409.
25. Tomioka, M. et al. 2006. The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans. Neuron 51: 613-625.