Antiproliferative activity of guava leaf extract via inhibition of prostaglandin endoperoxide H synthase isoforms

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 80, Issue 5-6, 2009, Pages 239-245

  Kawakami, Yuki ^a   Nakamura, Tomomi ^a   Hosokawa, Tomoko ^a   Suzuki Yamamoto, Toshiko ^a   Yamashita, Hiromi ^a   Kimoto, Masumi ^a   Tsuji, Hideaki ^a   Yoshida, Hideki ^b   Hada, Takahiko ^b   Takahashi, Yoshitaka ^a  

^a OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^b Bizen Chemical Co Ltd   (Japan)

Author keywords

Cyclooxygenase; Prostaglandin endoperoxide H synthase; Prostaglandin hydroperoxidase; Psidium guajava

Indexed keywords

13 HYDROXYOCTADECADIENOIC ACID; 9 HYDROXYOCTADECADIENOIC ACID; FATTY ACID DERIVATIVE; GUAVA EXTRACT; ISOENZYME; LINOLEIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXIDASE; PROSTAGLANDIN E2; PROSTAGLANDIN ENDOPEROXIDE; PROSTAGLANDIN ENDOPEROXIDE H; PROSTAGLANDIN HYDROPEROXIDASE; PROSTAGLANDIN SYNTHASE; QUERCETIN; RECOMBINANT ENZYME; RECOMBINANT PROSTAGLANDIN ENDOPEROXIDE 1; RECOMBINANT PROSTAGLANDIN ENDOPEROXIDE 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOMA CELL; CATALYSIS; COLON CARCINOMA; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SUBSTRATE; GENETIC TRANSFECTION; GUAVA; HUMAN; HUMAN CELL; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; HUMANS; ISOENZYMES; LINOLEIC ACID; LINOLEIC ACIDS; LINOLEIC ACIDS, CONJUGATED; PLANT EXTRACTS; PLANT LEAVES; PSIDIUM; RECOMBINANT PROTEINS;

PSIDIUM; PSIDIUM GUAJAVA;

EID: 68649115021     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2009.04.006     Document Type: Article

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