-
2
-
-
0000216808
-
Gaucher disease
-
Scriver C.R., Sly W.S., Childs B., Beaudet A.L., Valle D., Kinzler K.W., and Vogelstein B. (Eds), McGraw-Hill Inc.
-
Beutler E., and Grabowski G.A. Gaucher disease. In: Scriver C.R., Sly W.S., Childs B., Beaudet A.L., Valle D., Kinzler K.W., and Vogelstein B. (Eds). The Metabolic and Molecular Bases of Inherited Disease (2001), McGraw-Hill Inc. 3635-3668
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 3635-3668
-
-
Beutler, E.1
Grabowski, G.A.2
-
3
-
-
33749062163
-
Genetic diseases of sphingolipid metabolism: pathological mechanisms and therapeutic options
-
Kacher Y., and Futerman A.H. Genetic diseases of sphingolipid metabolism: pathological mechanisms and therapeutic options. FEBS Lett. 580 (2006) 5510-5517
-
(2006)
FEBS Lett.
, vol.580
, pp. 5510-5517
-
-
Kacher, Y.1
Futerman, A.H.2
-
4
-
-
17644422131
-
Gaucher disease: pathological mechanisms and modern management
-
Jmoudiak M., and Futerman A.H. Gaucher disease: pathological mechanisms and modern management. Br. J. Haematol. 129 (2005) 178-188
-
(2005)
Br. J. Haematol.
, vol.129
, pp. 178-188
-
-
Jmoudiak, M.1
Futerman, A.H.2
-
7
-
-
0037378110
-
Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis
-
Jeyakumar M., Thomas R., Elliot-Smith E., Smith D.A., van der Spoel A.C., d'Azzo A., Perry V.H., Butters T.D., Dwek R.A., and Platt F.M. Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. Brain 126 (2003) 974-987
-
(2003)
Brain
, vol.126
, pp. 974-987
-
-
Jeyakumar, M.1
Thomas, R.2
Elliot-Smith, E.3
Smith, D.A.4
van der Spoel, A.C.5
d'Azzo, A.6
Perry, V.H.7
Butters, T.D.8
Dwek, R.A.9
Platt, F.M.10
-
8
-
-
0032805835
-
Cytokines in Gaucher's disease
-
Barak V., Acker M., Nisman B., Kalickman I., Abrahamov A., Zimran A., and Yatziv S. Cytokines in Gaucher's disease. Eur. Cytokine Network 10 (1999) 205-210
-
(1999)
Eur. Cytokine Network
, vol.10
, pp. 205-210
-
-
Barak, V.1
Acker, M.2
Nisman, B.3
Kalickman, I.4
Abrahamov, A.5
Zimran, A.6
Yatziv, S.7
-
9
-
-
0031213523
-
Elevated levels of M-CSF, sCD14 and IL8 in type 1 Gaucher disease
-
Hollak C.E., Evers L., Aerts J.M., and van Oers M.H. Elevated levels of M-CSF, sCD14 and IL8 in type 1 Gaucher disease. Blood Cells Mol. Dis. 23 (1997) 201-212
-
(1997)
Blood Cells Mol. Dis.
, vol.23
, pp. 201-212
-
-
Hollak, C.E.1
Evers, L.2
Aerts, J.M.3
van Oers, M.H.4
-
10
-
-
0031018508
-
Pro-inflammatory cytokines and the pathogenesis of Gaucher's disease: increased release of interleukin-6 and interleukin-10
-
Allen M.J., Myer B.J., Khokher A.M., Rushton N., and Cox T.M. Pro-inflammatory cytokines and the pathogenesis of Gaucher's disease: increased release of interleukin-6 and interleukin-10. QJM 90 (1997) 19-25
-
(1997)
QJM
, vol.90
, pp. 19-25
-
-
Allen, M.J.1
Myer, B.J.2
Khokher, A.M.3
Rushton, N.4
Cox, T.M.5
-
12
-
-
4344593367
-
Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages
-
Boven L.A., van Meurs M., Boot R.G., Mehta A., Boon L., Aerts J.M., and Laman J.D. Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages. Am. J. Clin. Pathol. 122 (2004) 359-369
-
(2004)
Am. J. Clin. Pathol.
, vol.122
, pp. 359-369
-
-
Boven, L.A.1
van Meurs, M.2
Boot, R.G.3
Mehta, A.4
Boon, L.5
Aerts, J.M.6
Laman, J.D.7
-
13
-
-
0023840304
-
Active site directed inhibition of a cytosolic beta-glucosidase from calf liver by bromoconduritol B epoxide and bromoconduritol F
-
Legler G., and Bieberich E. Active site directed inhibition of a cytosolic beta-glucosidase from calf liver by bromoconduritol B epoxide and bromoconduritol F. Arch. Biochem. Biophys. 260 (1988) 437-442
-
(1988)
Arch. Biochem. Biophys.
, vol.260
, pp. 437-442
-
-
Legler, G.1
Bieberich, E.2
-
14
-
-
0036251767
-
Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage
-
Mizukami H., Mi Y., Wada R., Kono M., Yamashita T., Liu Y., Werth N., Sandhoff R., Sandhoff K., and Proia R.L. Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage. J. Clin. Invest. 109 (2002) 1215-1221
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1215-1221
-
-
Mizukami, H.1
Mi, Y.2
Wada, R.3
Kono, M.4
Yamashita, T.5
Liu, Y.6
Werth, N.7
Sandhoff, R.8
Sandhoff, K.9
Proia, R.L.10
-
15
-
-
0012721072
-
Reduced rates of axonal and dendritic growth in embryonic hippocampal neurones cultured from a mouse model of Sandhoff disease
-
Pelled D., Riebeling C., van Echten-Deckert G., Sandhoff K., and Futerman A.H. Reduced rates of axonal and dendritic growth in embryonic hippocampal neurones cultured from a mouse model of Sandhoff disease. Neuropathol. Appl. Neurobiol. 29 (2003) 341-349
-
(2003)
Neuropathol. Appl. Neurobiol.
, vol.29
, pp. 341-349
-
-
Pelled, D.1
Riebeling, C.2
van Echten-Deckert, G.3
Sandhoff, K.4
Futerman, A.H.5
-
16
-
-
0029113867
-
Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism
-
Sango K., Yamanaka S., Hoffmann A., Okuda Y., Grinberg A., Westphal H., McDonald M.P., Crawley J.N., Sandhoff K., Suzuki K., and Proia R.L. Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism. Nat. Genet. 11 (1995) 170-176
-
(1995)
Nat. Genet.
, vol.11
, pp. 170-176
-
-
Sango, K.1
Yamanaka, S.2
Hoffmann, A.3
Okuda, Y.4
Grinberg, A.5
Westphal, H.6
McDonald, M.P.7
Crawley, J.N.8
Sandhoff, K.9
Suzuki, K.10
Proia, R.L.11
-
17
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
18
-
-
0023820535
-
Macrophages exposed in vitro to conduritol B epoxide resemble Gaucher cells
-
Newburg D.S., Shea T.B., Yatziv S., Raghavan S.S., and McCluer R.H. Macrophages exposed in vitro to conduritol B epoxide resemble Gaucher cells. Exp. Mol. Pathol. 48 (1988) 317-323
-
(1988)
Exp. Mol. Pathol.
, vol.48
, pp. 317-323
-
-
Newburg, D.S.1
Shea, T.B.2
Yatziv, S.3
Raghavan, S.S.4
McCluer, R.H.5
-
19
-
-
0023917082
-
Gaucher-like changes in human blood-derived macrophages induced by beta-glucocerebrosidase inhibition
-
Yatziv S., Newburg D.S., Livni N., Barfi G., and Kolodny E.H. Gaucher-like changes in human blood-derived macrophages induced by beta-glucocerebrosidase inhibition. J. Lab. Clin. Med. 111 (1988) 416-420
-
(1988)
J. Lab. Clin. Med.
, vol.111
, pp. 416-420
-
-
Yatziv, S.1
Newburg, D.S.2
Livni, N.3
Barfi, G.4
Kolodny, E.H.5
-
20
-
-
2942675199
-
Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes
-
Trajkovic-Bodennec S., Bodennec J., and Futerman A.H. Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. Blood Cells Mol. Dis. 33 (2004) 77-82
-
(2004)
Blood Cells Mol. Dis.
, vol.33
, pp. 77-82
-
-
Trajkovic-Bodennec, S.1
Bodennec, J.2
Futerman, A.H.3
-
21
-
-
34248536519
-
Changes in macrophage morphology in a Gaucher disease model are dependent on CTP:phosphocholine cytidylyltransferase alpha
-
Kacher Y., Golan A., Pewzner-Jung Y., and Futerman A.H. Changes in macrophage morphology in a Gaucher disease model are dependent on CTP:phosphocholine cytidylyltransferase alpha. Blood Cells Mol. Dis. 39 (2007) 124-129
-
(2007)
Blood Cells Mol. Dis.
, vol.39
, pp. 124-129
-
-
Kacher, Y.1
Golan, A.2
Pewzner-Jung, Y.3
Futerman, A.H.4
-
22
-
-
0032478309
-
Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure
-
Liu Y., Suzuki K., Reed J.D., Grinberg A., Westphal H., Hoffmann A., Doring T., Sandhoff K., and Proia R.L. Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 2503-2508
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 2503-2508
-
-
Liu, Y.1
Suzuki, K.2
Reed, J.D.3
Grinberg, A.4
Westphal, H.5
Hoffmann, A.6
Doring, T.7
Sandhoff, K.8
Proia, R.L.9
-
23
-
-
2142653517
-
Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization
-
Nagalakshmi M.L., Murphy E., McClanahan T., and de Waal Malefyt R. Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization. Int. Immunopharmacol. 4 (2004) 577-592
-
(2004)
Int. Immunopharmacol.
, vol.4
, pp. 577-592
-
-
Nagalakshmi, M.L.1
Murphy, E.2
McClanahan, T.3
de Waal Malefyt, R.4
-
24
-
-
0025889028
-
IL-10 inhibits cytokine production by activated macrophages
-
Fiorentino D.F., Zlotnik A., Mosmann T.R., Howard M., and O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147 (1991) 3815-3822
-
(1991)
J. Immunol.
, vol.147
, pp. 3815-3822
-
-
Fiorentino, D.F.1
Zlotnik, A.2
Mosmann, T.R.3
Howard, M.4
O'Garra, A.5
-
25
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R., Lohler J., Rennick D., Rajewsky K., and Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75 (1993) 263-274
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
26
-
-
0028815553
-
Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance
-
Berg D.J., Kuhn R., Rajewsky K., Muller W., Menon S., Davidson N., Grunig G., and Rennick D. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J. Clin. Invest. 96 (1995) 2339-2347
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2339-2347
-
-
Berg, D.J.1
Kuhn, R.2
Rajewsky, K.3
Muller, W.4
Menon, S.5
Davidson, N.6
Grunig, G.7
Rennick, D.8
-
27
-
-
0031569474
-
Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration
-
Pajkrt D., Camoglio L., Tiel-van Buul M.C., de Bruin K., Cutler D.L., Affrime M.B., Rikken G., van der Poll T., ten Cate J.W., and van Deventer S.J. Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration. J. Immunol. 158 (1997) 3971-3977
-
(1997)
J. Immunol.
, vol.158
, pp. 3971-3977
-
-
Pajkrt, D.1
Camoglio, L.2
Tiel-van Buul, M.C.3
de Bruin, K.4
Cutler, D.L.5
Affrime, M.B.6
Rikken, G.7
van der Poll, T.8
ten Cate, J.W.9
van Deventer, S.J.10
-
28
-
-
0027478367
-
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia
-
Gerard C., Bruyns C., Marchant A., Abramowicz D., Vandenabeele P., Delvaux A., Fiers W., Goldman M., and Velu T. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J. Exp. Med. 177 (1993) 547-550
-
(1993)
J. Exp. Med.
, vol.177
, pp. 547-550
-
-
Gerard, C.1
Bruyns, C.2
Marchant, A.3
Abramowicz, D.4
Vandenabeele, P.5
Delvaux, A.6
Fiers, W.7
Goldman, M.8
Velu, T.9
-
29
-
-
0027408695
-
Interleukin 10 protects mice from lethal endotoxemia
-
Howard M., Muchamuel T., Andrade S., and Menon S. Interleukin 10 protects mice from lethal endotoxemia. J. Exp. Med. 177 (1993) 1205-1208
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1205-1208
-
-
Howard, M.1
Muchamuel, T.2
Andrade, S.3
Menon, S.4
-
30
-
-
34248351431
-
Dissecting the cytokine network
-
Muller W. Dissecting the cytokine network. Cell Immunol. 244 (2006) 162-164
-
(2006)
Cell Immunol.
, vol.244
, pp. 162-164
-
-
Muller, W.1
-
31
-
-
0033144893
-
Macrophage TNF mRNA expression induced by LPS is regulated by sphingomyelin metabolites
-
Lo C.J., Fu M., Lo F.R., and Cryer H.G. Macrophage TNF mRNA expression induced by LPS is regulated by sphingomyelin metabolites. Shock 11 (1999) 411-415
-
(1999)
Shock
, vol.11
, pp. 411-415
-
-
Lo, C.J.1
Fu, M.2
Lo, F.R.3
Cryer, H.G.4
-
32
-
-
34548515043
-
Ceramide inhibits LPS-induced production of IL-5, IL-10, and IL-13 from mast cells
-
Chiba N., Masuda A., Yoshikai Y., and Matsuguchi T. Ceramide inhibits LPS-induced production of IL-5, IL-10, and IL-13 from mast cells. J. Cell. Physiol. 213 (2007) 126-136
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 126-136
-
-
Chiba, N.1
Masuda, A.2
Yoshikai, Y.3
Matsuguchi, T.4
-
33
-
-
63749118967
-
A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages
-
10.1111/j.1365-2567.2008.02928.x
-
Goldsmith M., Avni D., Levy-Rimler G., Mashiach R., Ernst O., Levi M., Webb B., Meijler M.M., Gray N.S., Rosen H., and Zor T. A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages. Immunology (2008) 10.1111/j.1365-2567.2008.02928.x
-
(2008)
Immunology
-
-
Goldsmith, M.1
Avni, D.2
Levy-Rimler, G.3
Mashiach, R.4
Ernst, O.5
Levi, M.6
Webb, B.7
Meijler, M.M.8
Gray, N.S.9
Rosen, H.10
Zor, T.11
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