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Volumn 110, Issue 8, 2009, Pages 459-464

A response to infection in patients with severe sepsis - Do we need a "Stage-Directed Therapy Concept"?

Author keywords

Infection; Inflammatory response; Severe sepsis; Therapeutic intervention

Indexed keywords

ARTICLE; HUMAN; PATHOPHYSIOLOGY; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 68649098283     PISSN: 00069248     EISSN: 13360345     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (40)
  • 1
    • 0037389094 scopus 로고    scopus 로고
    • 2001 SCCM/ESICM/ACCP/ ATS/SIS international sepsis definitions conference
    • Levy MM, Fink MP, Marshall JC et al. 2001 SCCM/ESICM/ACCP/ ATS/SIS international sepsis definitions conference. Crit Care Med 2003; 31 (4): 1250-1256.
    • (2003) Crit Care Med , vol.31 , Issue.4 , pp. 1250-1256
    • Levy, M.M.1    Fink, M.P.2    Marshall, J.C.3
  • 3
    • 33646003577 scopus 로고    scopus 로고
    • The contribution of biophysical lung injury to the development of biotrauma
    • Dos Santos CC, Slutsky AS. The contribution of biophysical lung injury to the development of biotrauma. Annu Rev Physiol 2006; 68: 585-618.
    • (2006) Annu Rev Physiol , vol.68 , pp. 585-618
    • Dos Santos, C.C.1    Slutsky, A.S.2
  • 5
    • 0017764878 scopus 로고
    • Oedema and vasodilatation in inflammation: the relevance of prostaglandins
    • Williams TJ. Oedema and vasodilatation in inflammation: the relevance of prostaglandins. Postgrad Med J 1977; 53 (625): 660-662.
    • (1977) Postgrad Med J , vol.53 , Issue.625 , pp. 660-662
    • Williams, T.J.1
  • 6
    • 0242290221 scopus 로고    scopus 로고
    • Leukocyte adhesion: an exquisite balance of hydrodynamic and molecular forces
    • Tees DF, Goetz DJ. Leukocyte adhesion: an exquisite balance of hydrodynamic and molecular forces. News Physiol Sci 2003; 18 (5): 186-190.
    • (2003) News Physiol Sci , vol.18 , Issue.5 , pp. 186-190
    • Tees, D.F.1    Goetz, D.J.2
  • 7
    • 0035217872 scopus 로고    scopus 로고
    • Regulatory role of cytokines in disseminated intravascular coagulation
    • Van der Poll T, de Jonge E, Levi M. Regulatory role of cytokines in disseminated intravascular coagulation. Semin Thromb Hemost 2001; 27 (6): 639-651.
    • (2001) Semin Thromb Hemost , vol.27 , Issue.6 , pp. 639-651
    • Van der Poll, T.1    de Jonge, E.2    Levi, M.3
  • 9
    • 13944274907 scopus 로고    scopus 로고
    • Cytokines and vascular reactivity in resistance arteries
    • Vila E, Salaices M. Cytokines and vascular reactivity in resistance arteries. Amer J Physiol Heart Circ Physiol 2005; 288 (3): H1016-H1021.
    • (2005) Amer J Physiol Heart Circ Physiol , vol.288 , Issue.3
    • Vila, E.1    Salaices, M.2
  • 10
    • 0032437418 scopus 로고    scopus 로고
    • Microvascular endothelial cell control of peripheral vascular resistance during sepsis
    • Tucker JJ, Wilson MA, Wead WB, Garrison RN. Microvascular endothelial cell control of peripheral vascular resistance during sepsis. Arch Surg 1998; 133 (12): 1335-1342.
    • (1998) Arch Surg , vol.133 , Issue.12 , pp. 1335-1342
    • Tucker, J.J.1    Wilson, M.A.2    Wead, W.B.3    Garrison, R.N.4
  • 11
    • 33745932547 scopus 로고    scopus 로고
    • Compartmentalization of the inflammatory response in sepsis and SIRS
    • Cavaillon JM, Annane D. Compartmentalization of the inflammatory response in sepsis and SIRS. J Endotoxin Res 2006; 12 (3): 151-170.
    • (2006) J Endotoxin Res , vol.12 , Issue.3 , pp. 151-170
    • Cavaillon, J.M.1    Annane, D.2
  • 12
    • 0032770246 scopus 로고    scopus 로고
    • Freeman BD et al. Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
    • Hotchkiss RS, Swanson PE, Freeman BD et al. Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 1999; 27 (7): 1230-1251.
    • (1999) Crit Care Med , vol.27 , Issue.7 , pp. 1230-1251
    • Hotchkiss, R.S.1    Swanson, P.E.2
  • 13
    • 1342331785 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure
    • Brealey D, Karyampudi S, Jacques TS et al. Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure. Amer J Physiol Regul Integr Comp Physiol 2004; 286 (3): R491-R497.
    • (2004) Amer J Physiol Regul Integr Comp Physiol , vol.286 , Issue.3
    • Brealey, D.1    Karyampudi, S.2    Jacques, T.S.3
  • 14
    • 54049115160 scopus 로고    scopus 로고
    • Cellular dysfunction in sepsis
    • Singer M. Cellular dysfunction in sepsis. Clin Chest Med 2008; 29 (4): 655-660.
    • (2008) Clin Chest Med , vol.29 , Issue.4 , pp. 655-660
    • Singer, M.1
  • 15
    • 0033638849 scopus 로고    scopus 로고
    • The sympathetic nerve - an integrative interface between two supersystems: the brain and the immune system
    • Elenkov IJ, Wilder RL, Chrousos GP, Vizi ES. The sympathetic nerve - an integrative interface between two supersystems: the brain and the immune system. Pharmacol Rev 2000; 52 (4): 595-638.
    • (2000) Pharmacol Rev , vol.52 , Issue.4 , pp. 595-638
    • Elenkov, I.J.1    Wilder, R.L.2    Chrousos, G.P.3    Vizi, E.S.4
  • 16
    • 0029037126 scopus 로고
    • The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
    • Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. New Engl J Med 1995; 332 (20): 1351-1362.
    • (1995) New Engl J Med , vol.332 , Issue.20 , pp. 1351-1362
    • Chrousos, G.P.1
  • 17
    • 0034531569 scopus 로고    scopus 로고
    • Fever and the heat shock response: distinct, partially overlapping processes
    • Hasday JD, Singh IS. Fever and the heat shock response: distinct, partially overlapping processes. Cell Stress Chaperones 2000; 5 (5): 471-480.
    • (2000) Cell Stress Chaperones , vol.5 , Issue.5 , pp. 471-480
    • Hasday, J.D.1    Singh, I.S.2
  • 18
    • 0035136458 scopus 로고    scopus 로고
    • Leucocyte response and anti-inflammatory cytokines in community acquired pneumonia
    • Kolling UK, Hansen F, Braun J, Rink L, Katus HA, Dalhoff K. Leucocyte response and anti-inflammatory cytokines in community acquired pneumonia. Thorax 2001; 56 (2): 121-125.
    • (2001) Thorax , vol.56 , Issue.2 , pp. 121-125
    • Kolling, U.K.1    Hansen, F.2    Braun, J.3    Rink, L.4    Katus, H.A.5    Dalhoff, K.6
  • 19
    • 0037180778 scopus 로고    scopus 로고
    • The inflammatory reflex
    • Tracey KJ. The inflammatory reflex. Nature 2002; 420 (6917): 853-859.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 853-859
    • Tracey, K.J.1
  • 20
    • 23844517664 scopus 로고    scopus 로고
    • The vagus nerve and the nicotinic anti-inflammatory pathway
    • Ulloa L. The vagus nerve and the nicotinic anti-inflammatory pathway. Nat Rev Drug Discov 2005; 4 (8): 673-684.
    • (2005) Nat Rev Drug Discov , vol.4 , Issue.8 , pp. 673-684
    • Ulloa, L.1
  • 21
    • 0035135739 scopus 로고    scopus 로고
    • Normal responses to injury prevent systemic inflammation and can be immunosuppressive
    • Munford RS, Pugin J. Normal responses to injury prevent systemic inflammation and can be immunosuppressive. Amer J Resp Crit Care Med 2001; 163 (2): 316-321.
    • (2001) Amer J Resp Crit Care Med , vol.163 , Issue.2 , pp. 316-321
    • Munford, R.S.1    Pugin, J.2
  • 22
    • 13244288781 scopus 로고    scopus 로고
    • The "cytokine profile": a code for sepsis
    • Ulloa L, Tracey KJ. The "cytokine profile": a code for sepsis. Trends Mol Med 2005; 11 (2): 56-63.
    • (2005) Trends Mol Med , vol.11 , Issue.2 , pp. 56-63
    • Ulloa, L.1    Tracey, K.J.2
  • 24
    • 27144553471 scopus 로고    scopus 로고
    • The microcirculation is the motor of sepsis
    • Ince C. The microcirculation is the motor of sepsis. Crit Care 2005; 9(Suppl4): S13-S19.
    • (2005) Crit Care , vol.9 , Issue.SUPPL. 4
    • Ince, C.1
  • 25
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. New Engl J Med 2003; 348 (2): 138-150.
    • (2003) New Engl J Med , vol.348 , Issue.2 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 26
    • 26444606369 scopus 로고    scopus 로고
    • The multiple organ dysfunction syndrome and late-phase mortality in sepsis
    • Englert JA, Fink MP. The multiple organ dysfunction syndrome and late-phase mortality in sepsis. Curr Infect Dis Rep 2005; 7 (5): 335-341.
    • (2005) Curr Infect Dis Rep , vol.7 , Issue.5 , pp. 335-341
    • Englert, J.A.1    Fink, M.P.2
  • 27
    • 0036705805 scopus 로고    scopus 로고
    • Is severe sepsis a neuroendocrine disease?
    • Munford RS, Tracey KJ. Is severe sepsis a neuroendocrine disease? Mol Med 2002; 8 (8): 437-442.
    • (2002) Mol Med , vol.8 , Issue.8 , pp. 437-442
    • Munford, R.S.1    Tracey, K.J.2
  • 28
    • 29644435702 scopus 로고    scopus 로고
    • Glucocorticoids and sepsis
    • Allary J, Annane D. Glucocorticoids and sepsis. Minerva Anestesiol 2005; 71 (12): 759-768.
    • (2005) Minerva Anestesiol , vol.71 , Issue.12 , pp. 759-768
    • Allary, J.1    Annane, D.2
  • 29
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29(7): 1303-1310.
    • (2001) Crit Care Med , vol.29 , Issue.7 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 30
    • 18744375171 scopus 로고    scopus 로고
    • Fever control in septic shock: beneficial or harmful?
    • Su F, Nguyen ND, Wang Z, Cai Y, Rogiers P, Vincent JL. Fever control in septic shock: beneficial or harmful? Shock 2005; 23 (6): 516-520.
    • (2005) Shock , vol.23 , Issue.6 , pp. 516-520
    • Su, F.1    Nguyen, N.D.2    Wang, Z.3    Cai, Y.4    Rogiers, P.5    Vincent, J.L.6
  • 31
    • 0029148091 scopus 로고
    • The prevalence of nosoco-mial infection in intensive care units in Europe: Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC Internati onal Advisory Committee
    • Vincent JL, Bihari D, Suter PM et al. The prevalence of nosoco-mial infection in intensive care units in Europe: Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC Internati onal Advisory Committee. J Amer Med Ass 1995; 274 (8): 639-644.
    • (1995) J Amer Med Ass , vol.274 , Issue.8 , pp. 639-644
    • Vincent, J.L.1    Bihari, D.2    Suter, P.M.3
  • 32
    • 33744527833 scopus 로고    scopus 로고
    • Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
    • Kumar A, Roberts D, Wood KE et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006; 34 (6): 1589-1596.
    • (2006) Crit Care Med , vol.34 , Issue.6 , pp. 1589-1596
    • Kumar, A.1    Roberts, D.2    Wood, K.E.3
  • 33
    • 41749114059 scopus 로고    scopus 로고
    • 2008 update of international guidelines for the management of severe sepsis and septic shock: should we change our current clinical practice?
    • Jaeschke RZ, Brozek JL, Dellinger RP. 2008 update of international guidelines for the management of severe sepsis and septic shock: should we change our current clinical practice? Pol Arch Med Wewn 2008; 118 (3): 92-95.
    • (2008) Pol Arch Med Wewn , vol.118 , Issue.3 , pp. 92-95
    • Jaeschke, R.Z.1    Brozek, J.L.2    Dellinger, R.P.3
  • 34
    • 0035829842 scopus 로고    scopus 로고
    • Early goal-directed therapy in the treatment of severe sepsis and septic shock
    • Rivers E, Nguyen B, Havstad S et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. New Engl J Med 2001; 345 (19): 1368-1377.
    • (2001) New Engl J Med , vol.345 , Issue.19 , pp. 1368-1377
    • Rivers, E.1    Nguyen, B.2    Havstad, S.3
  • 35
    • 0028872009 scopus 로고
    • A trial of goal-oriented hemo-dynamic therapy in critically ill patients
    • Gattinoni L, Brazzi L, Pelosi P et al. A trial of goal-oriented hemo-dynamic therapy in critically ill patients. New Engl J Med 1995; 333 (16): 1025-1032.
    • (1995) New Engl J Med , vol.333 , Issue.16 , pp. 1025-1032
    • Gattinoni, L.1    Brazzi, L.2    Pelosi, P.3
  • 36
    • 0028275095 scopus 로고
    • Elevation of systemic oxygen delivery in the treatment of critically ill patients
    • Hayes MA, Timmins AC, Yau EH, Palazzo M, Hinds CJ, Watson D. Elevation of systemic oxygen delivery in the treatment of critically ill patients. New Engl J Med 1994; 330 (24): 1717-1722.
    • (1994) New Engl J Med , vol.330 , Issue.24 , pp. 1717-1722
    • Hayes, M.A.1    Timmins, A.C.2    Yau, E.H.3    Palazzo, M.4    Hinds, C.J.5    Watson, D.6
  • 37
    • 34247127759 scopus 로고    scopus 로고
    • Strategies to modulate cellular energetic metabolism during sepsis
    • Protti A, Singer M. Strategies to modulate cellular energetic metabolism during sepsis. Novartis Found Symp 2007; 280: 7-16.
    • (2007) Novartis Found Symp , vol.280 , pp. 7-16
    • Protti, A.1    Singer, M.2
  • 38
    • 25444492831 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
    • Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL et al. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. New Engl J Med 2005; 353 (13): 1332-1341.
    • (2005) New Engl J Med , vol.353 , Issue.13 , pp. 1332-1341
    • Abraham, E.1    Laterre, P.F.2    Garg, R.3    Levy, H.4    Talwar, D.5    Trzaskoma, B.L.6
  • 39
    • 26444604781 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment
    • Vincent JL, Bernard GR, Beale R, Doig C, Putensen C, Dhai-naut JF et al. Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Crit Care Med 2005; 33 (10): 2266-2277.
    • (2005) Crit Care Med , vol.33 , Issue.10 , pp. 2266-2277
    • Vincent, J.L.1    Bernard, G.R.2    Beale, R.3    Doig, C.4    Putensen, C.5    Dhai-naut, J.F.6


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