Kupffer cell depletion abolishes induction of interleukin-10 and permits sustained overexpression of tumor necrosis factor alpha messenger RNA in the regenerating rat liver

Hepatology

Volumn 25, Issue 4, 1997, Pages 889-895

  Rai, Rudra M ^a   Loffreda, Stefan ^a   Karp, Christopher L ^a   Yang, Shi Qi ^a   Lin, Hui Zi ^a   Diehl, Anna Mae ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DOWN REGULATION; GENE EXPRESSION; KUPFFER CELL; LIVER REGENERATION; LIVER RESECTION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT;

ANIMALS; BASE SEQUENCE; CYTOKINES; DNA PRIMERS; GADOLINIUM; GENE EXPRESSION; HEPATECTOMY; INTERLEUKIN-10; KUPFFER CELLS; LIVER REGENERATION; MALE; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030914670     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250417     Document Type: Article

References (20)

1. Higgins G, Anderson R. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931;12:186-202.
2. Leist M, Gantner F, Jilg S, Wendel A. Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J Immunol 1995;154:1307-1316.
3. Feingold K, Soued M, Grunfeld C. Tumor necrosis factor stimulates DNA synthesis in the liver of intact rats. Biochem Biophys Res Commun 1988; 153:576-582.
4. Akerman P, Cote P, Yang S, McClain C, Nelson S, Bagby G, Diehl AM. Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. Am J Physiol 1992;263:G579-585.
5. Zhu X, Zellweger R, Zhu X, Ayala A, Chaudry IH. Cytokine gene expression in splenic macrophages and Kupffer cells following haemorrhage. Cytokine 1995;7:8-14.
6. Nagata Y, Tanaka K, Orita K. Endotoxin-induced liver injury after extended hepatectomy and the role of Kupffer cells in the rat. Surg Today 1994;24:441-448.
7. Hardonk MJ, Dijkhuis FW, Hulstaert C, Koudstaal J. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J Leukoc Biol 1992;52:296-302.
8. Rai R, Yang SQ, McClain C, Karp CL, Klein AS, Diehl AM. Kupffer cell depletion by gadolinium chloride enhances liver regeneration after partial hepatectomy in rats. Am J Physiol 1996;270:G909-G918.
9. Bogdan C, Paik J, Vodovotz Y, Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J Biol Chem 1992;267:23301-23308.
10. Nicod LP, Habre F, Dayer JM, Boehringer N. Interleukin-10 decreases tumor necrosis factor alpha and beta in alloreactions induced by human lung dendritic cells and macrophages. Am J Respir Cell Mol Biol 1995;13: 83-90.
11. Bogdan C, Vodovotz Y, Nathan C. Macrophage deactivation by IL-10. J Exp Med 1991;174:1549-1555.
12. Berg DJ, Kuhn R, Rajewsky K, Muller W, Menon S, Davidson N, Rennick D. Interleukin-10 (IL-10) is a central regulator of the response to LPS in murine models of endotoxic shock and the Schwartzman reaction but not endotoxin tolerance. J Clin Invest 1995;96:2339-2347.
13. Hoyle GW, Hill RL. Structure of the gene for a carbohydrate-binding receptor unique to rat kupffer cells. J Biol Chem 1991;266:1850-1857.
14. Eichbaum QG, Iyer R, Raveh DP, Mathieu C, Ezekowitz RA. Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma R1b gene is mediated by a functional PU.1 site and a transcription initiator consensus. J Exp Med 1994;179:1985-1996.
15. Klein A, Zhadkewich M, Margolick J, Winkelstein J, Bulkley G. Quantitative discrimination of hepatic reticuloendothelial clearance and phagocytic killing. J Leukoc Biol 1994;55:248-252.
16. Corti A, Poiesi C, Merli S, Cassani G. Tumor necrosis factor (TNF) alpha quantification by ELISA and bioassay: effects of TNF alpha-soluble TNF receptor (p55) complex dissociation during assay incubations. J Immunol Methods 1994;177:191-198.
17. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidine thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 62:156-161.
18. Diehl AM, Yin M, Fleckenstein J, Yang SQ, Lin HZ, Brenner DA, Westwick J, et al. Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. Am J Physiol 1994;267:G552-G561.
19. Karp CL, el-Safi SH, Wynn TA, Satti MM, Kordofani AM, Hashim FA, Hag-Ali M, et al. In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma [Comments]. J Clin Invest 1993;91:1644-1648.
20. Gavreili Y, Sherman Y, Ben-Sasson S. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.