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Volumn 47, Issue 8, 2009, Pages 1810-1818

Cytotoxicity, mutagenicity, and tumorigenicity of mainstream smoke from three reference cigarettes machine-smoked to the same yields of total particulate matter per cigarette

Author keywords

Cigarette mainstream smoke; Cytotoxicity; Mutagenicity; Skin painting; Smoking regimen; Tumorigenicity

Indexed keywords

CIGARETTE SMOKE;

EID: 68649086379     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.04.048     Document Type: Article
Times cited : (26)

References (52)
  • 1
    • 0022160578 scopus 로고
    • Multistage models of carcinogenesis
    • Armitage P. Multistage models of carcinogenesis. Environ. Health Perspect. 63 (1985) 195-201
    • (1985) Environ. Health Perspect. , vol.63 , pp. 195-201
    • Armitage, P.1
  • 2
    • 0027050771 scopus 로고
    • Cytotoxic and morphological effects of phenylpropanolamine, caffeine, nicotine, and some of their metabolites studied in vitro
    • Babich H., and Borenfreund E. Cytotoxic and morphological effects of phenylpropanolamine, caffeine, nicotine, and some of their metabolites studied in vitro. Toxicol. In Vitro 6 (1992) 493-502
    • (1992) Toxicol. In Vitro , vol.6 , pp. 493-502
    • Babich, H.1    Borenfreund, E.2
  • 3
    • 33746991732 scopus 로고    scopus 로고
    • Smoke generation inside a burning cigarette: modifying combustion to develop cigarettes that may be less hazardous to health
    • Baker R.R. Smoke generation inside a burning cigarette: modifying combustion to develop cigarettes that may be less hazardous to health. Progr. Energy Combust. Sci. 32 (2006) 373-385
    • (2006) Progr. Energy Combust. Sci. , vol.32 , pp. 373-385
    • Baker, R.R.1
  • 4
    • 1842609944 scopus 로고    scopus 로고
    • An overview of the effects of tobacco ingredients on smoke chemistry and toxicity
    • Baker R.R., Massey E.D., and Smith G. An overview of the effects of tobacco ingredients on smoke chemistry and toxicity. Food Chem. Toxicol. 42S (2004) S53-S83
    • (2004) Food Chem. Toxicol. , vol.42 S
    • Baker, R.R.1    Massey, E.D.2    Smith, G.3
  • 6
    • 0020049498 scopus 로고
    • An empirical approach to the statistical analysis of mutagenesis data from the Salmonella test
    • Bernstein L., Kaldor J., McCann J., and Pike M.C. An empirical approach to the statistical analysis of mutagenesis data from the Salmonella test. Mutat. Res. 97 (1982) 267-281
    • (1982) Mutat. Res. , vol.97 , pp. 267-281
    • Bernstein, L.1    Kaldor, J.2    McCann, J.3    Pike, M.C.4
  • 7
    • 0021990499 scopus 로고
    • Toxicity determined in vitro by morphological alterations and Neutral Red absorption
    • Borenfreund E., and Puerner J.A. Toxicity determined in vitro by morphological alterations and Neutral Red absorption. Toxicol. Lett. 24 (1985) 119-124
    • (1985) Toxicol. Lett. , vol.24 , pp. 119-124
    • Borenfreund, E.1    Puerner, J.A.2
  • 8
    • 77954577665 scopus 로고
    • The function and mechanism of promoters of carcinogenesis
    • Boutwell R.K. The function and mechanism of promoters of carcinogenesis. Crit. Rev. Toxicol. 2 (1974) 419-443
    • (1974) Crit. Rev. Toxicol. , vol.2 , pp. 419-443
    • Boutwell, R.K.1
  • 10
    • 0034433874 scopus 로고    scopus 로고
    • A comparison of the mainstream smoke chemistry and mutagenicity of a representative sample of the US cigarette market with two Kentucky reference cigarettes (K1R4F and K1R5F)
    • Chepiga T.A., Morton M.J., Murphy P.A., Avalos J.T., Bombick B.R., Doolittle D.J., Bogerding M.F., and Swauger J.E. A comparison of the mainstream smoke chemistry and mutagenicity of a representative sample of the US cigarette market with two Kentucky reference cigarettes (K1R4F and K1R5F). Food Chem. Toxicol. 38 (2000) 949-962
    • (2000) Food Chem. Toxicol. , vol.38 , pp. 949-962
    • Chepiga, T.A.1    Morton, M.J.2    Murphy, P.A.3    Avalos, J.T.4    Bombick, B.R.5    Doolittle, D.J.6    Bogerding, M.F.7    Swauger, J.E.8
  • 11
    • 0019967579 scopus 로고
    • The tumorigenicity of smoke condensates from cigarettes containing different amounts of Cytrel assessed by mouse skin painting
    • Coggins C.R.E., Haroz R.K., Lam R., and Morgan K.T. The tumorigenicity of smoke condensates from cigarettes containing different amounts of Cytrel assessed by mouse skin painting. Toxicology 23 (1982) 177-185
    • (1982) Toxicology , vol.23 , pp. 177-185
    • Coggins, C.R.E.1    Haroz, R.K.2    Lam, R.3    Morgan, K.T.4
  • 12
    • 14644390892 scopus 로고    scopus 로고
    • Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions
    • Counts M.E., Morton M.J., Laffoon S.W., Cox R.H., and Lipowicz P.J. Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions. Regul. Toxicol. Pharmacol. 41 (2005) 185-227
    • (2005) Regul. Toxicol. Pharmacol. , vol.41 , pp. 185-227
    • Counts, M.E.1    Morton, M.J.2    Laffoon, S.W.3    Cox, R.H.4    Lipowicz, P.J.5
  • 13
    • 33750623725 scopus 로고    scopus 로고
    • Development of a commercial "market map" comparison methodology for evaluating new or non-conventional cigarettes
    • Counts M.E., Hsu F.S., and Tewes F.J. Development of a commercial "market map" comparison methodology for evaluating new or non-conventional cigarettes. Regul. Toxicol. Pharmacol. 46 (2006) 225-242
    • (2006) Regul. Toxicol. Pharmacol. , vol.46 , pp. 225-242
    • Counts, M.E.1    Hsu, F.S.2    Tewes, F.J.3
  • 15
    • 42749086216 scopus 로고    scopus 로고
    • Genotoxicity of 10 cigarette smoke condensates in four test systems: comparisons between assays and condensates - Corrigendum
    • DeMarini D.M., Ramadevi G., Szudlinska A., Rao M., Recio L., Kehl M., Kirby P.E., Polzin G., and Richter P.A. Genotoxicity of 10 cigarette smoke condensates in four test systems: comparisons between assays and condensates - Corrigendum. Mutat. Res. 652 (2008) 208
    • (2008) Mutat. Res. , vol.652 , pp. 208
    • DeMarini, D.M.1    Ramadevi, G.2    Szudlinska, A.3    Rao, M.4    Recio, L.5    Kehl, M.6    Kirby, P.E.7    Polzin, G.8    Richter, P.A.9
  • 16
    • 0004132384 scopus 로고
    • The University of Kentucky Printing Services, Lexington KY
    • Diana J.N., and Vaught A. Research Cigarettes (1980), The University of Kentucky Printing Services, Lexington KY
    • (1980) Research Cigarettes
    • Diana, J.N.1    Vaught, A.2
  • 18
    • 0344665695 scopus 로고    scopus 로고
    • A comparison of in vitro toxicities of cigarette smoke condensate from Eclipse cigarettes and four commercially available ultra low-"tar" cigarettes
    • Foy J.W., Bombick B.R., Bombick D.W., Doolittle D.J., Mosberg A.T., and Swauger J.E. A comparison of in vitro toxicities of cigarette smoke condensate from Eclipse cigarettes and four commercially available ultra low-"tar" cigarettes. Food Chem. Toxicol. 42 (2004) 237-243
    • (2004) Food Chem. Toxicol. , vol.42 , pp. 237-243
    • Foy, J.W.1    Bombick, B.R.2    Bombick, D.W.3    Doolittle, D.J.4    Mosberg, A.T.5    Swauger, J.E.6
  • 19
    • 0032722409 scopus 로고    scopus 로고
    • Toxicologic evaluation of flavor ingredients added to cigarette tobacco: skin painting bioassay of cigarette smoke condensate in SENCAR mice
    • Gaworski C.L., Heck J.D., Bennett M.B., and Wenk M.L. Toxicologic evaluation of flavor ingredients added to cigarette tobacco: skin painting bioassay of cigarette smoke condensate in SENCAR mice. Toxicology 139 (1999) 1-17
    • (1999) Toxicology , vol.139 , pp. 1-17
    • Gaworski, C.L.1    Heck, J.D.2    Bennett, M.B.3    Wenk, M.L.4
  • 22
    • 0026329361 scopus 로고
    • Ultralow-yield cigarettes and type of ventilation: the role of ventilation blocking
    • Höfer I., Nil R., and Bättig K. Ultralow-yield cigarettes and type of ventilation: the role of ventilation blocking. Pharmacol. Biochem. Behav. 40 (1991) 907-914
    • (1991) Pharmacol. Biochem. Behav. , vol.40 , pp. 907-914
    • Höfer, I.1    Nil, R.2    Bättig, K.3
  • 25
    • 0005896457 scopus 로고
    • ISO, International Standard Organization, Determination of Total and Nicotine-free Dry Particulate Matter using Routine Analytical Smoking Machine
    • ISO, International Standard Organization, 1991. Guideline 4387, Determination of Total and Nicotine-free Dry Particulate Matter using Routine Analytical Smoking Machine.
    • (1991) Guideline , pp. 4387
  • 26
    • 0026647044 scopus 로고
    • Carcinogens in tobacco smoke: benzo(a)pyrene from Canadian cigarettes and cigarette tobacco
    • Kaiserman M.J., and Rickert W.S. Carcinogens in tobacco smoke: benzo(a)pyrene from Canadian cigarettes and cigarette tobacco. Am. J. Public Health 82 (1992) 1023-1026
    • (1992) Am. J. Public Health , vol.82 , pp. 1023-1026
    • Kaiserman, M.J.1    Rickert, W.S.2
  • 27
    • 0034679230 scopus 로고    scopus 로고
    • Official cigarette tests are misleading: use a two-stage, compensating test
    • Kozlowski L.T., and O'Connor R.J. Official cigarette tests are misleading: use a two-stage, compensating test. Lancet 355 (2000) 2159-2161
    • (2000) Lancet , vol.355 , pp. 2159-2161
    • Kozlowski, L.T.1    O'Connor, R.J.2
  • 28
    • 34547843550 scopus 로고    scopus 로고
    • Cytotoxicity and gene expression profiles in cell cultures exposed to whole smoke from three types of cigarettes
    • Lu B., Kerepesi L., Wisse L., Hitchman K., and Meng Q.R. Cytotoxicity and gene expression profiles in cell cultures exposed to whole smoke from three types of cigarettes. Toxicol. Sci. 98 (2007) 469-478
    • (2007) Toxicol. Sci. , vol.98 , pp. 469-478
    • Lu, B.1    Kerepesi, L.2    Wisse, L.3    Hitchman, K.4    Meng, Q.R.5
  • 29
    • 33645512584 scopus 로고    scopus 로고
    • Cigarette smoking and lung cancer: modelling total exposure and intensity
    • Lubin J.H., and Caporaso N.E. Cigarette smoking and lung cancer: modelling total exposure and intensity. Cancer Epidemiol. Biomarkers Prev. 15 (2006) 517-523
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 517-523
    • Lubin, J.H.1    Caporaso, N.E.2
  • 31
    • 0020533372 scopus 로고
    • Reviewed methods for the Salmonella mutagenicity test
    • Maron D.M., and Ames B.N. Reviewed methods for the Salmonella mutagenicity test. Mutat. Res. 113 (1983) 173-215
    • (1983) Mutat. Res. , vol.113 , pp. 173-215
    • Maron, D.M.1    Ames, B.N.2
  • 32
    • 0001108982 scopus 로고    scopus 로고
    • Cigarette design and materials
    • Davis D.L., and Nielsen M.T. (Eds), Blackwell, Science, Oxford, UK
    • Norman A. Cigarette design and materials. In: Davis D.L., and Nielsen M.T. (Eds). Tobacco, Production, Chemistry and Technology (1999), Blackwell, Science, Oxford, UK 353-387
    • (1999) Tobacco, Production, Chemistry and Technology , pp. 353-387
    • Norman, A.1
  • 34
    • 68649102105 scopus 로고    scopus 로고
    • Peeler, C.L., 1996. Cigarette testing and the federal trade commission: a historical overview. In: Report of the NCI Expert Committee, US Department of Health and Human Services, Public Health Service (Eds.), Smoking and Tobacco Control. Monograph 7. The FTC Cigarette Test Method for Determining Tar, Nicotine, and Carbon Monoxide Yields of US Cigarettes. National Institute of Health, Bethesda, MD.
    • Peeler, C.L., 1996. Cigarette testing and the federal trade commission: a historical overview. In: Report of the NCI Expert Committee, US Department of Health and Human Services, Public Health Service (Eds.), Smoking and Tobacco Control. Monograph 7. The FTC Cigarette Test Method for Determining Tar, Nicotine, and Carbon Monoxide Yields of US Cigarettes. National Institute of Health, Bethesda, MD.
  • 35
    • 0036802564 scopus 로고    scopus 로고
    • Evaluation of eight in vitro assays for assessing the cytotoxicity of cigarette smoke condensate
    • Putnam K.P., Bombick D.W., and Doolittle D.J. Evaluation of eight in vitro assays for assessing the cytotoxicity of cigarette smoke condensate. Toxicol. In Vitro 16 (2002) 599-607
    • (2002) Toxicol. In Vitro , vol.16 , pp. 599-607
    • Putnam, K.P.1    Bombick, D.W.2    Doolittle, D.J.3
  • 37
    • 33947214401 scopus 로고    scopus 로고
    • Effect of smoking conditions and methods of collection on the mutagenicity and cytotoxicity of cigarette mainstream smoke
    • Rickert W.S., Trivedi A.H., Momin R.A., Wright W.G., and Lauterbach J.H. Effect of smoking conditions and methods of collection on the mutagenicity and cytotoxicity of cigarette mainstream smoke. Toxicol. Sci. 96 (2007) 285-293
    • (2007) Toxicol. Sci. , vol.96 , pp. 285-293
    • Rickert, W.S.1    Trivedi, A.H.2    Momin, R.A.3    Wright, W.G.4    Lauterbach, J.H.5
  • 38
    • 0025106564 scopus 로고
    • Mouse skin bioassay of smoke condensates from cigarettes containing different levels of cocoa
    • Roemer E., and Hackenberg U. Mouse skin bioassay of smoke condensates from cigarettes containing different levels of cocoa. Food Addit. Contam. 7 (1990) 563-569
    • (1990) Food Addit. Contam. , vol.7 , pp. 563-569
    • Roemer, E.1    Hackenberg, U.2
  • 39
    • 0036132804 scopus 로고    scopus 로고
    • Evaluation of the potential effects of ingredients added to cigarettes. Part 3: In vitro genotoxicity and cytotoxicity
    • Roemer E., Tewes F.J., Meisgen T.J., Veltel D.J., and Carmines E.L. Evaluation of the potential effects of ingredients added to cigarettes. Part 3: In vitro genotoxicity and cytotoxicity. Food Chem. Toxicol. 40 (2002) 105-111
    • (2002) Food Chem. Toxicol. , vol.40 , pp. 105-111
    • Roemer, E.1    Tewes, F.J.2    Meisgen, T.J.3    Veltel, D.J.4    Carmines, E.L.5
  • 40
    • 0348047603 scopus 로고    scopus 로고
    • Chemical composition, cytotoxicity, and mutagenicity of smoke from US commercial and reference cigarettes smoked under two sets of machine smoking conditions
    • Roemer E., Stabbert R., Rustemeier K., Veltel D.J., Meisgen T.J., Reininghaus W., Carchman R.A., Gaworski C.L., and Podraza K.F. Chemical composition, cytotoxicity, and mutagenicity of smoke from US commercial and reference cigarettes smoked under two sets of machine smoking conditions. Toxicology 195 (2004) 31-52
    • (2004) Toxicology , vol.195 , pp. 31-52
    • Roemer, E.1    Stabbert, R.2    Rustemeier, K.3    Veltel, D.J.4    Meisgen, T.J.5    Reininghaus, W.6    Carchman, R.A.7    Gaworski, C.L.8    Podraza, K.F.9
  • 41
    • 0032801604 scopus 로고    scopus 로고
    • Smoking behaviour and compensation: a review of the literature
    • Scherer G. Smoking behaviour and compensation: a review of the literature. Psychopharmacology (Berl.) 145 (1999) 1-20
    • (1999) Psychopharmacology (Berl.) , vol.145 , pp. 1-20
    • Scherer, G.1
  • 42
    • 68649108199 scopus 로고    scopus 로고
    • Schorp, M.K., 2005. Summary of literature data on smoking topography. In: A Review of Human Smoking Behaviour Data and Recommendations for a New ISO Standard for the Machine Smoking of Cigarettes. Report of the AD HOC WG9 Smoking Behaviour Review Team to ISO/TC 126 WG 9. Retrieved at: (Bates-No. 551963717).
    • Schorp, M.K., 2005. Summary of literature data on smoking topography. In: A Review of Human Smoking Behaviour Data and Recommendations for a New ISO Standard for the Machine Smoking of Cigarettes. Report of the AD HOC WG9 Smoking Behaviour Review Team to ISO/TC 126 WG 9. Retrieved at: (Bates-No. 551963717).
  • 43
    • 33748750334 scopus 로고    scopus 로고
    • The mouse lymphoma thymidine kinase assay for the assessment and comparison of the mutagenic activity of cigarette mainstream smoke particulate phase
    • Schramke H., Meisgen T.J., Tewes F.J., Gomm W., and Roemer E. The mouse lymphoma thymidine kinase assay for the assessment and comparison of the mutagenic activity of cigarette mainstream smoke particulate phase. Toxicology 227 (2006) 193-210
    • (2006) Toxicology , vol.227 , pp. 193-210
    • Schramke, H.1    Meisgen, T.J.2    Tewes, F.J.3    Gomm, W.4    Roemer, E.5
  • 44
    • 26444483913 scopus 로고    scopus 로고
    • Statistical modeling and projections of lung cancer mortality in 4 industrialized countries
    • Shibuya K., Inoue M., and Lopez A.D. Statistical modeling and projections of lung cancer mortality in 4 industrialized countries. Int. J. Cancer 117 (2005) 476-485
    • (2005) Int. J. Cancer , vol.117 , pp. 476-485
    • Shibuya, K.1    Inoue, M.2    Lopez, A.D.3
  • 45
    • 0028907548 scopus 로고
    • A comparison of the mutagenicity of mainstream cigarette smoke condensate from a representative sample of the US cigarette commercial with a Kentucky reference cigarette (K1R4F)
    • Steele R.H., Payne V.M., Fulp C.W., Rees D.C., Lee C.K., and Doolittle D.J. A comparison of the mutagenicity of mainstream cigarette smoke condensate from a representative sample of the US cigarette commercial with a Kentucky reference cigarette (K1R4F). Mutat. Res. 342 (1995) 179-190
    • (1995) Mutat. Res. , vol.342 , pp. 179-190
    • Steele, R.H.1    Payne, V.M.2    Fulp, C.W.3    Rees, D.C.4    Lee, C.K.5    Doolittle, D.J.6
  • 48
    • 16744368637 scopus 로고    scopus 로고
    • United Kingdom Co-ordinating committee on cancer research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia
    • UKCCCR. United Kingdom Co-ordinating committee on cancer research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia. Br. J. Cancer 77 2 (1998) 1-10
    • (1998) Br. J. Cancer , vol.77 , Issue.2 , pp. 1-10
    • UKCCCR1
  • 49
    • 68649087692 scopus 로고
    • United States Consumer Products Safety Commission in Consultation with the US Department of Health and Human Services. Toxicity Testing Plan
    • US CPSC, United States Consumer Products Safety Commission, 1993. United States Consumer Products Safety Commission in Consultation with the US Department of Health and Human Services. Toxicity Testing Plan 5.
    • (1993) United States Consumer Products Safety Commission , pp. 5
    • CPSC, U.1
  • 50
    • 68649108668 scopus 로고    scopus 로고
    • Smoking and Tobacco Control
    • United States Department of Health and Human Services, Public Health Services, National Institutes of Health, National Cancer Institute, Bethesda, MD, USA
    • US DHHS, United States Department of Health and Human Services, 2001. Smoking and Tobacco Control. Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine. Public Health Services, National Institutes of Health, National Cancer Institute, Bethesda, MD, USA.
    • (2001) Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine
    • US, D.H.H.S.1
  • 51
    • 0003526589 scopus 로고    scopus 로고
    • Supplementary Guidance for Conducting Health Risk Assessment of Chemical Mixtures. EPA/630/R-00/002
    • United States Environmental Protection Agency, Washington, DC 20460
    • US EPA, United States Environmental Protection Agency, 2000. Supplementary Guidance for Conducting Health Risk Assessment of Chemical Mixtures. EPA/630/R-00/002. Risk Assessment Forum US EPA, Washington, DC 20460.
    • (2000) Risk Assessment Forum US EPA
    • US, E.P.A.1
  • 52
    • 34547409329 scopus 로고    scopus 로고
    • The role of skin painting in predicting lung cancer
    • Walaszek Z., Hanausek M., and Slaga T.J. The role of skin painting in predicting lung cancer. Int. J. Toxicol. 26 (2007) 345-351
    • (2007) Int. J. Toxicol. , vol.26 , pp. 345-351
    • Walaszek, Z.1    Hanausek, M.2    Slaga, T.J.3


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