Dimethylarsinic acid in drinking water changed the morphology of urinary bladder but not the expression of DNA repair genes of bladder transitional epithelium in F344 rats

Toxicologic Pathology

Volumn 37, Issue 4, 2009, Pages 425-437

  Wang, Amy ^a,c   Wolf, Douglas C ^b   Sen, Banalata ^c   Knapp, Geremy W ^b   Holladay, Steven D ^a   Huckle, William R ^a   Caceci, Thomas ^a   Robertson, John L ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Arsenic; Dimethylarsinic acid; DNA damage repair; Ultrastructure; Urothelium

Indexed keywords

ATM PROTEIN; CACODYLIC ACID; DNA DIRECTED DNA POLYMERASE BETA; DRINKING WATER; EXCISION REPAIR CROSS COMPLEMENTATION GROUP 3 PROTEIN; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER EPITHELIUM; CELL CULTURE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR GENE; EXCISION REPAIR; FEMALE; FISCHER 344 RAT; GENE; GENE EXPRESSION; MITOCHONDRION SWELLING; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PROCESSING; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSITIONAL CELL CARCINOMA;

ANIMALS; CACODYLIC ACID; CELL CYCLE PROTEINS; DNA HELICASES; DNA REPAIR; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LINEAR MODELS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEINS; URINARY BLADDER; UROTHELIUM; VACUOLES; WATER;

RATTUS;

EID: 68649083237     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623309334147     Document Type: Article

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