Arsenite-induced alterations of DNA photodamage repair and apoptosis after solar-simulation UVR in mouse keratinocytes in vitro

Environmental Health Perspectives

Volumn 113, Issue 8, 2005, Pages 983-986

  Wu, Feng ^a   Burns, Fredric J ^a   Zhang, Ronghe ^a   Uddin, Ahmed N ^a   Rossman, Toby G ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Arsenite; Mouse keratinocyte; Photodamage repair; Skin cancer; Solar simulation UVR

Indexed keywords

ARSENATE SODIUM; CASPASE 3; CASPASE 7; CYCLOBUTANE DERIVATIVE; GENOMIC DNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IN VITRO STUDY; KERATINOCYTE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; SOLAR ENERGY; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; ARSENITES; CELL LINE; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; KERATINOCYTES; MICE; PYRIMIDINE DIMERS; SODIUM COMPOUNDS; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 23844496688     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.7846     Document Type: Article

References (22)

1. Bender K, Blattner C, Knebel A, Iordanov M, Herrlich P, Rahmsdorf HJ. 1997. UV-induced signal transduction. J Photochem Photobiol B 37:1-17.
2. Brash DE, Ziegler A, Jonason AS, Simon JA, Kunala S. Leffell DJ. 1996. Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion. J Investig Dermatol Symp Proc 1:136-142.
3. Burns FJ, Uddin AN, Wu F, Nádas A, Rossman TG. 2004. Arsenic-induced enhancement of ultraviolet radiation carcinogenesis in mouse skin: a dose-response study. Environ Health Perspect 112:599-603.
4. de Gruijl FR, van Kranen HJ, Mullenders LH. 2001. UV-Induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J Photochem Photobiol B 63:19-27.
5. Hanawalt PC. 2001. Revisiting the rodent repsirudox. Environ Mol Mutagen 38:89-96.
6. Hartwig A. 2001. Zinc finger proteins as potential targets for toxic metal ions: differential effects on structure and function. Antioxid Redox Signal 3:625-634.
7. Hartwig A, Groblinghoff UD, Beyersmann D, Natarajan AT, Filon R, Mullenders LH. 1997. Interaction of arsenic (III) with nucleotide excision repair in UV-irradiated human fibroblasts. Carcinogenesis 18:399-405.
8. Kulesz-Martin M, Yoshida MA, Prestine L, Yuspa SH, Bertram JS. 1985. Mouse cell clones for improved quantitation of carcinogen-induced altered differentiation. Carcinogenesis 6:1245-1254.
9. Kulms D, Schwarz T. 2000. Molecular mechanisms of UV-induced apoptosis. Photodermatol Photoimmunol Photomed 16:195-201.
10. Li JH, Rossman TG. 1989. Inhibition of DNA ligase activity by arsenite: a possible mechanism of its comutagenesis. Mol Toxicol 2:1-9.
11. Li JH, Rossman TG. 1991. Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells. Biol Met 4:197-200
12. Liao WT, Chang KL, Vu CL, Chen OS, Chang LW, Yu HS. 2004. Arsenic induces human keratinocyte apoptosis by the FAS/FAS ligand pathway, which correlates with alterations in nuclear factor-kappa B and activator protein-1 activity. J Invest Oermatol 122:125-129.
13. Miller JH. 1985. Mutagenic specificity of ultraviolet light. J Mol Biol 182:45-65.
14. Mitchell DL, Haipek CA, Clarkson JM. 1985. (6-4) Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers. Mutat Res 143:109-112.
15. Mori T, Nakane M, Hattori T, Matsunaga T, Ihara M, Nikaido O. 1991. Simultaneous establishment of monoclonal antibodies specific for either cyclobutane pyrimidine dimer or (6-4) photoproduct from the same mouse immunized with ultra-violet-irradiated DNA. Photochem Photobiol 54:225-232.
16. Rossman TG. 2003. Mechanism of arsenic carcinogenesis: an integrated approach. Mutat Res 533:37-65.
17. Rossman TG, Uddin AN, Burns FJ, Bosland MC. 2001. Arsenite is a cocarcinogen with solar ultraviolet radiation for mouse skin: an animal model for arsenic carcinogenesis. Toxicol Appl Pharmacol 176:64-71.
18. Wang Z, Liu Y, Mori M, Kulesz-Martin M. 2002. Gene expression profiling of initiated epidermal cells with benign or malignant tumor fates. Carcinogenesis 23:635-643.
19. Yager JW, Wiencke JK. 1997. Inhibition of poly (ADP-ribose) polymerase by arsenite. Mutat Res 386:345-351.
20. Zhao CQ, Young MR, Diwan BA, Coogan TP, Waalkes MP. 1997. Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc Natl Acad Sci USA 94:10907-10912.
21. Zhuang L, Wang B, Sauder DN. 2000. Molecular mechanism of ultraviolet-induced keratinocyte apoptosis. J Interferon Cytokine Res 20:445-454.
22. Ziegler A, Leffell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, et al. 1993. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc Natl Acad Sci USA 90:4216-4220.