Effects of dietary dimethylarsinic acid on the urine and urothelium of rats

Carcinogenesis

Volumn 20, Issue 11, 1999, Pages 2171-2179

  Arnold, Lora L ^a   Cano, Martin ^a   John, Margaret St ^a   Eldan, Michal ^b   Van Gemert, Marcia ^c   Cohen, Samuel M ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Luxembourg Industries Pamol Ltd   (Israel)

^c LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CACODYLIC ACID; CALCIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER CARCINOGENESIS; CALCIUM URINE LEVEL; CELL LABELING; CONTROLLED STUDY; DIET; DOSE RESPONSE; FEMALE; HYPERPLASIA; KIDNEY CALCIFICATION; MALE; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; URINE; UROTHELIUM;

ANIMALS; BODY WEIGHT; BROMODEOXYURIDINE; CACODYLIC ACID; DIET; DRINKING BEHAVIOR; FEEDING BEHAVIOR; FEMALE; HYDROGEN-ION CONCENTRATION; MALE; MICROSCOPY, ELECTRON, SCANNING; RATS; RATS, INBRED F344; URINARY BLADDER NEOPLASMS; URINE; UROTHELIUM;

EID: 0032747707     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.11.2171     Document Type: Article

References (26)

1. van Gemert, M. and Eldan, M. (1998) Chronic carcinogenicity assessment of cacodylic acid. 3rd International Conference on Arsenic Exposure and Health Effects, San Diego, CA.
2. Wei, M., Wanibuchi, H., Yamamoto, S., Li, W. and Fukushima, S. (1999) Urinary bladder carcinogenicity of dimethylarsinic acid in male F344 rats. Carcinogenesis, in press.
3. Wanibuchi, H., Yamamoto, S., Chen, H., Yoshida, K., Endo, G., Hori, T. and Fukushima, S. (1996) Promoting effects of dimethylarsinic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in rats. Carcinogenesis, 17, 2435-2439.
4. Leonard, A. and Lauwerys, R.R. (1983) Carcinogenicity, teratogenicity and mutagenicity of arsenic. Mutat. Res., 75, 49-62.
5. Jacobson-Kram, D. and Montalbano, D. (1985) The reproductive effects assessment group's report on the mutagenicity of inorganic arsenic. Environ. Mutagen., 7, 787-804.
6. Wang, Z. and Rossman, T.G. (1996) The carcinogenicity of arsenic. In Chang, L.W. (ed.) Toxicology of Metals. CRC Press, Boca Raton, FL, pp. 219-227.
7. Rossman, T.G. (1998) Molecular and genetic toxicology of arsenic. In Rose, J. (ed.) Environmental Toxicology: Current Developments. Gordon and Breach Publishers, Amsterdam, The Netherlands. Volume 7, pp. 171-187.
8. International Agency for Research on Cancer. (1980) IARC Monographs on the Evaluation of the carcinogenic risk of chemicals to humans. IARC Scientific Publications Vol. 23, IARC, Lyon.
9. US Environmental Protection Agency (1997) Report on the Expert Panel on Arsenic Carcinogenicity. National Center for Environmental Assessment, US Environmental Protection Agency, Washington, DC.
10. Cohen, S.M. (1998) Urinary bladder carcinogenesis. Toxicol. Pathol., 26, 121-127.
11. Cohen, S.M. (1995) The role of urinary physiology and chemistry in bladder carcinogenesis. Food Chem. Toxicol., 33, 715-730.
12. Cohen, S.M., Fisher, M.J., Sakata, J., Cano, M., Schoenig, G.P., Chappel, C.I. and Garland, E.M. (1990) Comparative analysis of the proliferative response of the rat urinary bladder to sodium saccharin by light and scanning electron microscopy and autoradiography. Scanning Microsc., 4, 135-142.
13. Cohen, S.M., Cano, M., Garland, E.M., St John, M. and Arnold, L.L. (1995) Urinary and urothelial effects of sodium salts in male rats. Carcinogenesis, 16, 343-348.
14. Cohen, S.M., Garland, E.M., Cano, M., St John, M., Khachab, M. and Arnold, L.L. (1995) Effects of sodium ascorbate, sodium saccharin and ammonium chloride on the male rat urinary bladder. Carcinogenesis, 16, 2743-2750.
15. Arnold, L.L., Christenson, W.R., Cano, M., St John, M.K., Wahl, B.S. and Cohen, S.M. (1997) Tributyl phosphate effects on urine and bladder epithelium in male Sprague-Dawley rats. Fund. Applied Toxicol., 40, 247-255.
16. Smith, R.A., Christenson, W.R., Bartels, M.J., Arnold, L.L., St John, M.K., Cano, M., Wahle, B.S., McNett, D.A. and Cohen, S.M. (1998) Urinary physiologic and chemical metabolic effects on the urothelial cytotoxicity and potential genotoxicity of o-phenylphenol in male rats. Toxicol. Appl. Pharmacol., 150, 402-413.
17. Cohen, S.M., Cano, M., Johnson, L.S., St John, M.K., Asamoto, M., Garland, E.M., Thyssen, J.H., Sangha, G.K. and Van Goethem, D.L. (1994) Mitogenic effects of propoxur on male rat bladder urothelium. Carcinogenesis, 15, 2593-2597.
18. Fisher, M.J., Sakata, T., Tibbels, T.S., Smith, R.A., Patil, K., Khachab, M., Johansson, S.L. and Cohen, S.M. (1989) Effect of saccharin on urinary parameters in rats fed Prolab 3200 or AIN-76 diet. Food Chem. Toxicol., 27, 1-9.
19. Clayson, D.B., Fishbein, L. and Cohen, S.M. (1995) The effect of stones and other physical factors on the induction of rodent bladder cancer. Food Chem. Toxicol., 33, 771-784.
20. Cohen, S.M. (1983) Pathology of experimental bladder cancer in rodents. In Cohen, S.M. and Bryan, G.T. (eds) The Pathology of Bladder Cancer. CRC Press, Boca Raton, FL, Vol. II, pp. 1-40.
21. Sheehan, D.C. and Hrapchak, B.B. (eds) (1980) Pigments and Minerals. Theory and Practice of Histotechnology, 2nd Edn. C.V. Mosby Co., St Louis, MO, p. 227.
22. Cohen, S.M., Cano, M., Anderson, T. and Garland, E.M. (1996) Extensive handling of rats leads to mild urinary bladder hyperplasia. Toxicol. Pathol., 24, 251-257.
23. Aposhian, H.V. (1997) Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity. Ann. Rev. Pharmacol. Toxicol. 37, 397-419.
24. Abernathy, C.O., Chappel, W.R., Meek, M.E., Gibb, H. and Guo, H.R. (1996) Roundtable summary - is ingested inorganic arsenic a 'threshold' carcinogen? Fund. Applied Toxicol., 29, 168-175.
25. Cohen, S.M., Arnold, L.L., St John, M.K. and Cano, M. (1999) Evaluation of cell proliferative activity in the rat urinary bladder after feeding high doses of cacodylic acid. Proceedings of the Third International Conference on Arsenic Exposure and Health Effects, 12-15 July 1998, San Diego, CA.
26. Cohen, S.M., Arnold, L.L., St John, M.K., Cano, M., van Gemert, M. and Eldan, M. (1999) Effects of dimethylarsenic acid (DMA) on urinary parameters and bladder epithelium in female F344 rats. The Toxicologist, 48, 1086.