Association between 18F-fluoro-2-deoxy-D-glucose uptake values and tumor vitality: Prognostic value of positron emission tomography in early-stage non-small cell lung cancer

Journal of Thoracic Oncology

Volumn 4, Issue 7, 2009, Pages 822-828

  Dooms, Christophe ^a   Baardwijk, Angela Van ^b   Verbeken, Eric ^a   Suylen, Robert Jan Van ^b   Stroobants, Sigrid ^a   Ruysscher, Dirk De ^b   Vansteenkiste, Johan ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

FDG PET scan; Non small cell lung cancer; Prognosis; SUV

Indexed keywords

CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE IX; CASPASE 3; CD31 ANTIGEN; FLUORODEOXYGLUCOSE F 18; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN;

ACIDOSIS; ARTICLE; CANCER CELL; CANCER MORTALITY; CANCER RISK; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; CELL DENSITY; CELL HYPOXIA; CELL PH; CELL PROLIFERATION; DISEASE SEVERITY; DRUG UPTAKE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; MORPHOLOGY; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS;

EID: 68549136820     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3181a97df7     Document Type: Article

References (30)

1. Warburg O. The Metabolism of Tumours. London: Constable Press, 1930.
2. Ahuja V, Coleman R, Herndon J, Patz E. The prognostic significance of fluorodeoxyglucose positron emission tomography imaging for patients with non-small cell lung carcinoma. Cancer 1998;83:918-924. (Pubitemid 28401925)
3. Vansteenkiste JF, Stroobants S, Dupont P, et al. Prognostic importance of the standardized uptake value on (18)F-fluoro-2-deoxy-glucosepositron emission tomography scan in non-small cell lung cancer: an analysis of 125 cases. J Clin Oncol 1999;17:3201-3206. (Pubitemid 29470652)
4. Cerfolio R, Bryant A, Ohja B, Bartolucci AA. The maximum standardized uptake values on positron emission tomography of a non-small cell lung cancer predict stage, recurrence, and survival. J Thorac Cardiovasc Surg 2005;130:151-159. (Pubitemid 40941684)
5. Borst GR, Belderbos JS, Boellaard R, et al. Standardised FDG uptake: a prognostic factor for inoperable non-small cell lung cancer. Eur J Cancer 2005;41:1533-1541. (Pubitemid 40981834)
6. Berghmans T, Dusart M, Paesmans M, et al.; European Lung Cancer Working Party for the IASLC Lung Cancer Staging Project. Primary tumor standardized uptake value (SUVmax) measured on fluorodeoxyglucose positron emission tomography (FDG-PET) is of prognostic value for survival in non-small cell lung cancer (NSCLC). A systematic review and meta-analysis by the European Lung Cancer Working Partyfor the IASLC Lung Cancer Staging Project. J Thorac Oncol 2008;3: 6-12.
7. Vesselle H, Freeman J, Wiens L, et al. Fluorodeoxyglucose uptake of primary non-small cell lung cancer at positron emission tomography: new contrary data on prognostic role. Clin cancer Res 2007;13:3255-3263. (Pubitemid 46944910)
8. Downey R, Akhurst T, Gonen M, Park B, Rusch V. Fluorine-18 fluorodeoxyglucose positron emission tomographic maximal standardized uptake value predicts survival independent of clinical but not pathologic TNM staging of resected non-small cell lung cancer. J Thorac Cardiovasc Surg 2007;133:1419-1427. (Pubitemid 46802579)
9. Nguyen X, Lee W, Chung J, et al. FDG uptake, glucose transporter type1, and Ki-67 expressions in non-small cell lung cancer: correlations and prognostic values. Eur J Radiol 2007;62:214-219. (Pubitemid 46560344)
10. Higashi K, Ueda Y, Sakurai A, et al. Correlation of GLUT-1 glucose transporter expression with 18F-FDG uptake in non-small cell lung cancer. Eur J Nucl Med 2000;27:1778-1785.
11. Mamede M, Higashi T, Kitaichi M, et al. [18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung. Neoplasie 2005;7:369-379. (Pubitemid 40664226)
12. Vesselle H, Schmidt R, Pugsley J, et al. Lung cancer proliferation correlates with F18-fluorodeoxyglucose uptake by positron emission tomography. Clin Cancer Res 2000;6:3837-3844. (Pubitemid 30807072)
13. Higashi K, Ueda Y, Yagishita M, et al. FDG PET measurement of the proliferative potential of non-small cell lung cancer. J Nucl Med 2000; 41:85-92. (Pubitemid 30046688)
14. Sasaki M, Sugio K, Kuwabara Y, et al. Alterations of tumor suppressor genes (Rb, p16, p27 and p53) and an increased FDG uptake in lung cancer. Ann Nucl Med 2003;17:189-196. (Pubitemid 36834430)
15. van Baardwijk A, Dooms C, van Suylen RJ, et al. The maximum uptake of 18F-deoxyglucose on PET scan correlates with survival, hypoxia inducible factor-1α and GLUT-1 in non-small cell lung cancer. Eur J Cancer 2007;43:1392-1398. (Pubitemid 46874072)
16. Tateishi U, Nishihara H, Tsukamoto E, Morikawa T, Tamaki N, Miyasaka K. Lung tumors evaluated with FDG-PET and dynamic CT: the relationship between vascular density and glucose metabolism. J Comput Assist Tomogr 2002;26:185-190. (Pubitemid 34233362)
17. Koukourakis M, Giatromanolaki A, Harris A, Sivridis E. Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. Cancer Res 2006;66:632-637. (Pubitemid 43165922)
18. Weibel E. Stereological Methods: Practical Methods for Biological Morphometry, Vol.1 and 2. London: Academic Press, 1979.
19. Gundersen H, Bendtsen T, Korbo L, et al. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988;96:379-394. (Pubitemid 18145920)
20. Mery C, Pappas A, Burt B, et al. Diameter of non-small cell lung cancer correlates with long-term survival. Chest 2005;128:3255-3260.
21. Blum R, Jacob-Hirsch J, Amarglio N, Rechavi G, Kloog Y. RAS inhibition in glioblastoma down-regulates hypoxia-inducible factor 1-α, causing glycolysis shutdown and cell death. Cancer Res 2005;65:999-1006. (Pubitemid 40216462)
22. Elstrom R, Bauer D, Buzzai M, et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 2004;64:3892-3899. (Pubitemid 38697301)
23. Dang C, Semenza G. Oncogenic alterations of metabolism. Trends Biochem Sci 1999;24:68-72. (Pubitemid 29346576)
24. Lum JJ, Bui T, Gruber M, et al. The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev 2007;21:1037-1049. (Pubitemid 46686473)
25. Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007;26:225-239.
26. Semenza G, Jiang B, Leung S, et al. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 1996;271:32529-32537. (Pubitemid 27008669)
27. Wykoff C, Beasley N, Watson P, et al. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 2000;60:7075-7083. (Pubitemid 32059187)
28. Park H, Lyons J, Ohtsubo T, Song CW. Acidic environment causes apoptosis by increasing caspase activity. Br J Cancer 1999;80:1892-1897. (Pubitemid 29391271)
29. Dorai T, Sawczuk I, Pastorek J, Wiernik PH, Dutcher JP. The role of carbonic anhydrase IX overexpression in kidney cancer. Eur J Cancer 2005;41:2935-2947. (Pubitemid 41713134)
30. Schlappack O, Zimmerman A, Hill L. Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells. Br J Cancer 1991;64:663-670.