Impaired cAMP and Rac 1 signaling contribute to TNF-α-induced endothelial barrier breakdown in microvascular endothelium

Microcirculation

Volumn 16, Issue 6, 2009, Pages 521-533

  Schlegel, Nicolas ^a   Waschke, Jens ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

cAMP; Rac 1; Rho A; Rho kinase; TNF endothelial barrier

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CYCLIC AMP; CYTOTOXIC NECROTIZING FACTOR 1; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; FORSKOLIN; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; ROLIPRAM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; ELECTRIC RESISTANCE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GAP JUNCTION; HUMAN; HUMAN CELL; HYDRAULIC CONDUCTIVITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROVASCULATURE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR ENDOTHELIUM; VENULE; WESTERN BLOTTING;

AMIDES; ANIMALS; CELLS, CULTURED; CYCLIC AMP; ENDOTHELIUM; FEMALE; HUMANS; INTERCELLULAR JUNCTIONS; LYMPHOTOXIN-ALPHA; MALE; MICROCIRCULATION; NEUROPEPTIDES; PROTEIN KINASE INHIBITORS; PYRIDINES; RAC GTP-BINDING PROTEINS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; VENULES;

RATTUS;

EID: 68549112984     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1080/10739680902967427     Document Type: Article

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