Endothelial barrier stabilization by a cyclic tandem peptide targeting VE-cadherin transinteraction in vitro and in vivo

Journal of Cell Science

Volumn 122, Issue 10, 2009, Pages 1616-1625

  Heupel, Wolfgang Moritz ^a   Efthymiadis, Athina ^a   Schlegel, Nicolas ^a   Müller, Thomas ^a   Baumer, Yvonne ^a   Baumgartner, Werner ^b   Drenckhahn, Detlev ^a   Waschke, Jens ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Endothelial barrier; Inflammation; Peptide; TNF ; VE cadherin

Indexed keywords

ACTIN; CADHERIN; CALCIMYCIN; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VASCULAR ENDOTHELIAL CADHERIN; CALCIUM; CYCLOPEPTIDE; HYBRID PROTEIN; IONOPHORE; LEUKOCYTE ANTIGEN; PHOTOPROTEIN;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD VESSEL PERMEABILITY; CELL ADHESION; CELL CULTURE; CHO CELL; CONTROLLED STUDY; CYTOSKELETON; ENDOTHELIUM CELL; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; VASCULAR ENDOTHELIUM; VENULE; ANIMAL; BINDING SITE; CAPILLARY PERMEABILITY; CELL JUNCTION; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER AIDED DESIGN; COMPUTER SIMULATION; CRICETULUS; DIFFUSION; DRUG EFFECT; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; IMPEDANCE; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RAT; TIME; WISTAR RAT;

ADHERENS JUNCTIONS; ANIMALS; ANTIGENS, CD; BINDING SITES; CADHERINS; CALCIMYCIN; CALCIUM; CAPILLARY PERMEABILITY; CELL ADHESION; CHO CELLS; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; CRICETINAE; CRICETULUS; DIFFUSION; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMANS; IONOPHORES; LUMINESCENT PROTEINS; MICE; MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; TIME FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; VENULES;

EID: 67649978602     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.040212     Document Type: Article

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