Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile

Hypertension

Volumn 54, Issue 2, 2009, Pages 294-301

  Huynh, Ngan N ^a   Andrews, Karen L ^a   Head, Geoffrey A ^a   Khong, Sacha M L ^a   Mayorov, Dmitry N ^a   Murphy, Andrew J ^a   Lambert, Gavin ^a   Kiriazis, Helen ^a   Xu, Qi ^a   Du, Xiao Jun ^a   Chin Dusting, Jaye P F ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Arginase; Hypertension; L arginine; NO; Vasculature

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLCHOLINE; ADRENALIN; ARGINASE; ARGININE; CATECHOLAMINE; FASUDIL; NITRATE; NITRIC OXIDE; NITRITE; NORADRENALIN; PHENYLEPHRINE; RHO KINASE; UREA;

ADRENALIN BLOOD LEVEL; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL REACTIVITY; CATECHOLAMINE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; HEART FUNCTION; HYPERTENSION; KIDNEY; KNOCKOUT MOUSE; MEAN ARTERIAL PRESSURE; MOUSE; MOUSE STRAIN; NONHUMAN; NORADRENALIN BLOOD LEVEL; PHENOTYPE; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; UREA CYCLE; VASCULAR RING; VASOCONSTRICTION; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; BLOOD FLOW VELOCITY; BLOOD PRESSURE MEASUREMENT; C57BL MOUSE; COMPARATIVE STUDY; DISEASE MODEL; FEMALE; GENETICS; HEART FUNCTION TEST; MALE; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESSORECEPTOR REFLEX; PROBABILITY; RANDOMIZATION; SENSITIVITY AND SPECIFICITY; VASCULAR RESISTANCE;

ANALYSIS OF VARIANCE; ANIMALS; ARGINASE; ARGININE; BAROREFLEX; BLOOD FLOW VELOCITY; BLOOD PRESSURE DETERMINATION; CATECHOLAMINES; DISEASE MODELS, ANIMAL; FEMALE; HEART FUNCTION TESTS; HYPERTENSION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE; PHENOTYPE; PROBABILITY; RANDOM ALLOCATION; SENSITIVITY AND SPECIFICITY; UREA; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 68549092700     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.108.121731     Document Type: Article

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