메뉴 건너뛰기




Volumn 60, Issue 2, 2008, Pages 213-219

Anti-tumour effects of HL-37, a novel anthracene derivative, in-vivo and in-vitro

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACENE DERIVATIVE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; GLYCOPROTEIN P; HL 37; METALLOPROTEINASE; PROTEIN BCL XL; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 38949099327     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.60.2.0010     Document Type: Article
Times cited : (10)

References (37)
  • 1
    • 18144369714 scopus 로고    scopus 로고
    • Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]-carboxamide derivatives of 7-oxo-7H-benz[de]anthracene,7- oxo-7H-naphtho [1,2,3-de]quinoline, and 7-oxo-7Hbenzo[e]perimidine
    • Bu, X., Chen, J., Deady, L. W., Smith, C. L., Baguley, B. C., Greenhalgh, D., Yang, S., Denny, W. A. (2005) Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]-carboxamide derivatives of 7-oxo-7H-benz[de]anthracene,7- oxo-7H-naphtho [1,2,3-de]quinoline, and 7-oxo-7Hbenzo[e]perimidine. Bioorg. Med. Chem. 13: 3657-3665
    • (2005) Bioorg. Med. Chem , vol.13 , pp. 3657-3665
    • Bu, X.1    Chen, J.2    Deady, L.W.3    Smith, C.L.4    Baguley, B.C.5    Greenhalgh, D.6    Yang, S.7    Denny, W.A.8
  • 2
    • 39749089553 scopus 로고    scopus 로고
    • Amonafide, a topoisomerase II inhibitor, is unaffected by P-glycoprotein- mediated efflux
    • Chau, M., Christensen, J. L., Ajami, A. M., Capizzi, R. L. (2007) Amonafide, a topoisomerase II inhibitor, is unaffected by P-glycoprotein- mediated efflux. Leuk. Res. 32: 1563-1572
    • (2007) Leuk. Res , vol.32 , pp. 1563-1572
    • Chau, M.1    Christensen, J.L.2    Ajami, A.M.3    Capizzi, R.L.4
  • 3
    • 0020071909 scopus 로고
    • Activity of a novel anthracenyl bishydrazone, 9,10-anthracenedicarboxyaldehyde Bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] dihydrochloride, against experimental tumors in mice
    • Citarella, R. V., Wallace, R. E., Murdock, K. C., Angier, R. B., Durr, F. E., Forbes, M. (1982) Activity of a novel anthracenyl bishydrazone, 9,10-anthracenedicarboxyaldehyde Bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] dihydrochloride, against experimental tumors in mice. Cancer Res. 42: 440-444
    • (1982) Cancer Res , vol.42 , pp. 440-444
    • Citarella, R.V.1    Wallace, R.E.2    Murdock, K.C.3    Angier, R.B.4    Durr, F.E.5    Forbes, M.6
  • 4
    • 26944463091 scopus 로고    scopus 로고
    • Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation
    • Czyz, M., Szulawska, A., Bednarek, A. K., Duchler, M. (2005) Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation. Biochem. Pharmacol. 70: 1431-1444
    • (2005) Biochem. Pharmacol , vol.70 , pp. 1431-1444
    • Czyz, M.1    Szulawska, A.2    Bednarek, A.K.3    Duchler, M.4
  • 5
    • 0033555758 scopus 로고    scopus 로고
    • P-glycoprotein expression on normal and abnormally expanded natural killer cells and inhibition of P-glycoprotein function by cyclosporin A and its analogue, PSC833
    • Egashira, M., Kawamata, N., Sugimoto, K., Kaneko, T., Oshimi, K. (1999) P-glycoprotein expression on normal and abnormally expanded natural killer cells and inhibition of P-glycoprotein function by cyclosporin A and its analogue, PSC833. Blood 93: 599-606
    • (1999) Blood , vol.93 , pp. 599-606
    • Egashira, M.1    Kawamata, N.2    Sugimoto, K.3    Kaneko, T.4    Oshimi, K.5
  • 6
    • 33846892957 scopus 로고    scopus 로고
    • An in vitro model to study chemoresistance in non-Hodgkin' s lymphoma patients over-expressing mutant p53
    • Foroutan, B., Ruf, A. A., Jerwood, D., Anderson, D. (2007) An in vitro model to study chemoresistance in non-Hodgkin' s lymphoma patients over-expressing mutant p53. J. Pharmacol. Toxicol. Methods 55: 58-64
    • (2007) J. Pharmacol. Toxicol. Methods , vol.55 , pp. 58-64
    • Foroutan, B.1    Ruf, A.A.2    Jerwood, D.3    Anderson, D.4
  • 7
    • 35048880601 scopus 로고    scopus 로고
    • Immunization with liposome-anchored pegylated peptides modulates doxorubicin sensitivity in P-glycoprotein-expressing P388 cells
    • Gatouillat, G., Odot, J., Balasse, E., Nicolau, C., Tosi, P. F., Hickman, D. T., Lopez-Deber, M. P., Madoulet, C. (2007) Immunization with liposome-anchored pegylated peptides modulates doxorubicin sensitivity in P-glycoprotein-expressing P388 cells. Cancer Lett. 257: 165-171
    • (2007) Cancer Lett , vol.257 , pp. 165-171
    • Gatouillat, G.1    Odot, J.2    Balasse, E.3    Nicolau, C.4    Tosi, P.F.5    Hickman, D.T.6    Lopez-Deber, M.P.7    Madoulet, C.8
  • 8
    • 33745027196 scopus 로고    scopus 로고
    • Hu, G. Q., Xie, S. Q., Huang, W. L., Zhang, H. B. (2005) Synthesis and antibacterial activity of 8-substituted phenyl-1-pyridin-3-yl- 5H-bis[1,2,4]triazolo[3,4-b; 4′,3′-d][1,3,4] thiadiazines. Chin. Chem. Lett. 16: 723-726
    • Hu, G. Q., Xie, S. Q., Huang, W. L., Zhang, H. B. (2005) Synthesis and antibacterial activity of 8-substituted phenyl-1-pyridin-3-yl- 5H-bis[1,2,4]triazolo[3,4-b; 4′,3′-d][1,3,4] thiadiazines. Chin. Chem. Lett. 16: 723-726
  • 10
    • 34447342246 scopus 로고    scopus 로고
    • CJY, an isoflavone, reverses p-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells
    • Ji, B. S., He, L. (2007) CJY, an isoflavone, reverses p-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells. J. Pharm. Pharmacol. 59: 1011-1015
    • (2007) J. Pharm. Pharmacol , vol.59 , pp. 1011-1015
    • Ji, B.S.1    He, L.2
  • 11
    • 23844445265 scopus 로고    scopus 로고
    • Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells
    • Ji, B. S., He, L., Liu, G. Q. (2005) Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells. Life Sci. 77: 2221-2232
    • (2005) Life Sci , vol.77 , pp. 2221-2232
    • Ji, B.S.1    He, L.2    Liu, G.Q.3
  • 13
    • 0034005790 scopus 로고    scopus 로고
    • Preferential cytotoxicity for multidrug-resistant K562 cells using the combination of a photosensitizer and a cyanine dye
    • Kanofsky, J. R., Sima, P. D. (2000) Preferential cytotoxicity for multidrug-resistant K562 cells using the combination of a photosensitizer and a cyanine dye. J. Photochem. Photobiol. B: Biol. 54: 136-144
    • (2000) J. Photochem. Photobiol. B: Biol , vol.54 , pp. 136-144
    • Kanofsky, J.R.1    Sima, P.D.2
  • 14
    • 25844451162 scopus 로고    scopus 로고
    • Design, synthesis, and antiproliferative activity of some novel aminosubstituted xanthenones, able to overcome multidrug resistance toward MES-SA/Dx5 cells
    • Kostakis, I. K., Tenta, R., Pouli, N., Marakos, P., Skaltsounis, A. L., Pratsinis, H., Kletsas, D. (2005) Design, synthesis, and antiproliferative activity of some novel aminosubstituted xanthenones, able to overcome multidrug resistance toward MES-SA/Dx5 cells. Bioorg. Med. Chem. Lett. 15: 5057-5060
    • (2005) Bioorg. Med. Chem. Lett , vol.15 , pp. 5057-5060
    • Kostakis, I.K.1    Tenta, R.2    Pouli, N.3    Marakos, P.4    Skaltsounis, A.L.5    Pratsinis, H.6    Kletsas, D.7
  • 15
    • 33845672083 scopus 로고    scopus 로고
    • Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase. Implications for increasing its ability to inhibit the growth of sensitive and multidrug resistant leukaemia HL60 cells
    • Kostrzewa-Nowak, D., Paine, M. J., Korytowska, A., Serwatka, K., Piotrowska, S., Wolf, C. R., Tarasiuk, J. (2007) Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase. Implications for increasing its ability to inhibit the growth of sensitive and multidrug resistant leukaemia HL60 cells. Cancer Lett. 245: 252-262
    • (2007) Cancer Lett , vol.245 , pp. 252-262
    • Kostrzewa-Nowak, D.1    Paine, M.J.2    Korytowska, A.3    Serwatka, K.4    Piotrowska, S.5    Wolf, C.R.6    Tarasiuk, J.7
  • 17
    • 31044456677 scopus 로고    scopus 로고
    • Schisandrin B enhances doxorubicin-induced apoptosis of cancer cells but not normal cells
    • Li, L., Lu, Q., Shen, Y., Hu, X. (2006) Schisandrin B enhances doxorubicin-induced apoptosis of cancer cells but not normal cells. Biochem. Pharmacol. 71: 584-595
    • (2006) Biochem. Pharmacol , vol.71 , pp. 584-595
    • Li, L.1    Lu, Q.2    Shen, Y.3    Hu, X.4
  • 18
    • 8444250984 scopus 로고    scopus 로고
    • Antitumor effects of the partially purified polysaccharides from Antrodia camphorate and the mechanism of its action
    • Liu, J. J., Huang, T. S., Hsu, M. L., Chen, C. C., Lin, W. S., Lu, F. J., Chang, W. H. (2004) Antitumor effects of the partially purified polysaccharides from Antrodia camphorate and the mechanism of its action. Toxicol. Appl. Pharmacol. 201: 186-193
    • (2004) Toxicol. Appl. Pharmacol , vol.201 , pp. 186-193
    • Liu, J.J.1    Huang, T.S.2    Hsu, M.L.3    Chen, C.C.4    Lin, W.S.5    Lu, F.J.6    Chang, W.H.7
  • 20
    • 33646568511 scopus 로고    scopus 로고
    • Mechanisms and strategies to overcome multiple drug resistance in cancer
    • Ozben, T. (2006) Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett. 580: 2903-2909
    • (2006) FEBS Lett , vol.580 , pp. 2903-2909
    • Ozben, T.1
  • 21
    • 33746441944 scopus 로고    scopus 로고
    • Induction of apoptosis by Meretrix lusoria though reactive oxygen species production, glutathione depletion, and caspase activation in human leukemia cells
    • Pan, M. H., Huang, Y. T., Ho, C. T., Chang, C. I., Hsu, P. C., Pan, B. S. (2006) Induction of apoptosis by Meretrix lusoria though reactive oxygen species production, glutathione depletion, and caspase activation in human leukemia cells. Life Sci. 79: 1140-1152
    • (2006) Life Sci , vol.79 , pp. 1140-1152
    • Pan, M.H.1    Huang, Y.T.2    Ho, C.T.3    Chang, C.I.4    Hsu, P.C.5    Pan, B.S.6
  • 22
    • 15544391127 scopus 로고    scopus 로고
    • The cell cycle phases of DNA-damage and repair initiated by topoisomerase II-targeting chemotherapeutic drugs
    • Potter, A. J., Rabinovitch, P. S. (2005) The cell cycle phases of DNA-damage and repair initiated by topoisomerase II-targeting chemotherapeutic drugs. Mutat. Res. 572: 27-44
    • (2005) Mutat. Res , vol.572 , pp. 27-44
    • Potter, A.J.1    Rabinovitch, P.S.2
  • 23
    • 34248578176 scopus 로고    scopus 로고
    • Ethonafide-induced cytotoxicity is mediated by topoisomerase II inhibition in prostate cancer cells
    • Pourpak, A., Landowski, T. H., Dorr, R. T. (2007) Ethonafide-induced cytotoxicity is mediated by topoisomerase II inhibition in prostate cancer cells. J. Pharmacol. Exp. Ther. 321: 1109-1117
    • (2007) J. Pharmacol. Exp. Ther , vol.321 , pp. 1109-1117
    • Pourpak, A.1    Landowski, T.H.2    Dorr, R.T.3
  • 24
    • 33749556242 scopus 로고    scopus 로고
    • Effect of rhodoxanthin from Potamogeton crispus L. on cell apoptosis in Hea cells
    • Ren, D. D., Peng, G. H., Huang, H. X., Wang, H. B., Zhang, S. H. (2006) Effect of rhodoxanthin from Potamogeton crispus L. on cell apoptosis in Hea cells. Toxicol. In Vitro 20: 1411-1418
    • (2006) Toxicol. In Vitro , vol.20 , pp. 1411-1418
    • Ren, D.D.1    Peng, G.H.2    Huang, H.X.3    Wang, H.B.4    Zhang, S.H.5
  • 25
    • 0025821275 scopus 로고
    • Multidrug-resistant myeloma: Laboratory and clinical effects of verapamil as a chemosensitizer
    • Salmon, S. E., Dalton, W. S., Grogan, T. M., Plezia, P., Lehnert, M., Roe, D. J., Miller, T. P. (1991) Multidrug-resistant myeloma: laboratory and clinical effects of verapamil as a chemosensitizer. Blood 78: 44-50
    • (1991) Blood , vol.78 , pp. 44-50
    • Salmon, S.E.1    Dalton, W.S.2    Grogan, T.M.3    Plezia, P.4    Lehnert, M.5    Roe, D.J.6    Miller, T.P.7
  • 26
    • 34247141496 scopus 로고    scopus 로고
    • 3, 5-Dibenzoyl-4-(3-phenoxyphenyl) -1,4-dihydro-2,6-dimethylpyridine (DP7): A new multidrug resistance inhibitor devoid of effects on Langendorff-perfused rat heart
    • Saponara, S., Ferrara, A., Gorelli, B., Shah, A., Kawase, M., Motohashi, N., Molnar, J., Sgaragli, G., Fusi, F. (2007) 3, 5-Dibenzoyl-4-(3-phenoxyphenyl) -1,4-dihydro-2,6-dimethylpyridine (DP7): a new multidrug resistance inhibitor devoid of effects on Langendorff-perfused rat heart. Eur. J. Pharmacol. 563: 160-163
    • (2007) Eur. J. Pharmacol , vol.563 , pp. 160-163
    • Saponara, S.1    Ferrara, A.2    Gorelli, B.3    Shah, A.4    Kawase, M.5    Motohashi, N.6    Molnar, J.7    Sgaragli, G.8    Fusi, F.9
  • 27
    • 4644256896 scopus 로고    scopus 로고
    • The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoacridines. Implications for overcoming multidrug resistance towards leukaemia K562/DOX cells
    • Tarasiuk, J., Majewska, E., Seksek, O., Rogacka, D., Antonini, I., Garnier-Suillerot, A., Borowski, E. (2004) The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoacridines. Implications for overcoming multidrug resistance towards leukaemia K562/DOX cells. Biochem. Pharmacol. 68: 1815-182
    • (2004) Biochem. Pharmacol , vol.68 , pp. 1815-2182
    • Tarasiuk, J.1    Majewska, E.2    Seksek, O.3    Rogacka, D.4    Antonini, I.5    Garnier-Suillerot, A.6    Borowski, E.7
  • 28
    • 16244384650 scopus 로고    scopus 로고
    • Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies
    • Tarasiuk, J., Mazerski, J., Tkaczyk-Gobis, K., Borowski, E. (2005) Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies. Eur. J. Med. Chem. 40: 321-328
    • (2005) Eur. J. Med. Chem , vol.40 , pp. 321-328
    • Tarasiuk, J.1    Mazerski, J.2    Tkaczyk-Gobis, K.3    Borowski, E.4
  • 29
    • 27444441930 scopus 로고    scopus 로고
    • Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway
    • Wang, D. H., Wei, H. L., Zhao, H. S., Hao, C. Y., Min, Z. H., Liu, J. M. (2005) Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway. Pharmacol. Res. 52: 376-385
    • (2005) Pharmacol. Res , vol.52 , pp. 376-385
    • Wang, D.H.1    Wei, H.L.2    Zhao, H.S.3    Hao, C.Y.4    Min, Z.H.5    Liu, J.M.6
  • 30
    • 34249773997 scopus 로고    scopus 로고
    • Simultaneous suppression of multidrug resistance and antiapoptotic cellular defense induces apoptosis in chemoresistant human acute myeloid leukemia cells
    • Wang, X., Wang, C., Qin, Y. W., Yan, S. K., Gao, Y. R. (2007a) Simultaneous suppression of multidrug resistance and antiapoptotic cellular defense induces apoptosis in chemoresistant human acute myeloid leukemia cells. Leuk. Res. 31: 989-994
    • (2007) Leuk. Res , vol.31 , pp. 989-994
    • Wang, X.1    Wang, C.2    Qin, Y.W.3    Yan, S.K.4    Gao, Y.R.5
  • 31
    • 33947363752 scopus 로고    scopus 로고
    • Lgf-YL-9 induces apoptosis in human epidermoid carcinoma KB cells and multidrug resistant KBv200 cells via reactive oxygen species-independent mitochondrial pathway
    • Wang, X. H., Jia, D. Z., Liang, Y. J., Yan, S. L., Ding, Y., Chen, L. M., Shi, Z., Zeng, M. S., Liu, G. F., Fu, L. W. (2007b) Lgf-YL-9 induces apoptosis in human epidermoid carcinoma KB cells and multidrug resistant KBv200 cells via reactive oxygen species-independent mitochondrial pathway. Cancer Lett. 249: 256-270
    • (2007) Cancer Lett , vol.249 , pp. 256-270
    • Wang, X.H.1    Jia, D.Z.2    Liang, Y.J.3    Yan, S.L.4    Ding, Y.5    Chen, L.M.6    Shi, Z.7    Zeng, M.S.8    Liu, G.F.9    Fu, L.W.10
  • 33
    • 34248186686 scopus 로고    scopus 로고
    • Tryptanthrin inhibits MDR1 and reverses doxorubicin resistance in breast cancer cells
    • Yu, S. T., Chen, T. M., Tseng, S. Y., Chen, Y. H. (2007) Tryptanthrin inhibits MDR1 and reverses doxorubicin resistance in breast cancer cells. Biochem. Biophys. Res. Commun. 358: 79-84
    • (2007) Biochem. Biophys. Res. Commun , vol.358 , pp. 79-84
    • Yu, S.T.1    Chen, T.M.2    Tseng, S.Y.3    Chen, Y.H.4
  • 35
    • 33644851237 scopus 로고    scopus 로고
    • Syntheses and biological activities of 3′-azido disaccharide analogues of daunorubicin against drug-resistant leukemia
    • Zhang, G., Fang, L., Zhu, L., Zhong, Y., Wang, P. G., Sun, D. (2006) Syntheses and biological activities of 3′-azido disaccharide analogues of daunorubicin against drug-resistant leukemia. J. Med. Chem. 49: 1792-1799
    • (2006) J. Med. Chem , vol.49 , pp. 1792-1799
    • Zhang, G.1    Fang, L.2    Zhu, L.3    Zhong, Y.4    Wang, P.G.5    Sun, D.6
  • 36
    • 32844471774 scopus 로고    scopus 로고
    • Sorcin, an important gene associated with multidrug-resistance in human leukemia cells
    • Zhou, Y., Xu, Y., Tan, Y., Qi, J., Xiao, Y., Yang, C., Zhu, Z., Xiong, D. (2006) Sorcin, an important gene associated with multidrug-resistance in human leukemia cells. Leuk. Res. 30: 469-476
    • (2006) Leuk. Res , vol.30 , pp. 469-476
    • Zhou, Y.1    Xu, Y.2    Tan, Y.3    Qi, J.4    Xiao, Y.5    Yang, C.6    Zhu, Z.7    Xiong, D.8
  • 37
    • 27544456829 scopus 로고    scopus 로고
    • Syntheses and biological activities of daunorubicin analogs with uncommon sugars
    • Zhu, L., Cao, X., Chen, W., Zhang, G., Sun, D., Wang, P. G. (2005) Syntheses and biological activities of daunorubicin analogs with uncommon sugars. Biol. Med. Chem. 13: 6381-6387
    • (2005) Biol. Med. Chem , vol.13 , pp. 6381-6387
    • Zhu, L.1    Cao, X.2    Chen, W.3    Zhang, G.4    Sun, D.5    Wang, P.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.