메뉴 건너뛰기




Volumn 58, Issue 9, 2009, Pages 593-599

Hepatic protection by glycyrrhizin and inhibition of iNOS expression in concanavalin A-induced liver injury in mice

Author keywords

Concanavalin A liver injury; Glycyrrhizin; Hepatic protection; Inducible nitric oxide synthase

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; GLYCYRRHIZIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA;

EID: 68449099405     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-009-0024-8     Document Type: Article
Times cited : (40)

References (32)
  • 2
    • 0033173099 scopus 로고    scopus 로고
    • Glycyrrhizin protects mice from concanavalin A-induced hepatitis without affecting cytokine expression
    • T Okamoto T Kanda 1999 Glycyrrhizin protects mice from concanavalin A-induced hepatitis without affecting cytokine expression Int J Mol Med 4 149 152
    • (1999) Int J Mol Med , vol.4 , pp. 149-152
    • Okamoto, T.1    Kanda, T.2
  • 3
    • 0033978305 scopus 로고    scopus 로고
    • The protective effect of glycyrrhizin on anti-Fas antibody-induced hepatitis in mice
    • DOI 10.1016/S0014-2999(99)00807-9, PII S0014299999008079
    • T Okamoto 2000 The protective effect of glycyrrhizin on anti-Fas antibody-induced hepatitis in mice Eur J Pharmacol 387 229 232 (Pubitemid 30067820)
    • (2000) European Journal of Pharmacology , vol.387 , Issue.2 , pp. 229-232
    • Okamoto, T.1
  • 4
    • 0035900610 scopus 로고    scopus 로고
    • Glycyrrhizin and some analogues induce growth of primary cultured adult rat hepatocytes via epidermal growth factor receptors
    • M Kimura H Inoue K Hirabayashi H Natsume M Ogihara 2001 Glycyrrhizin and some analogues induce growth of primary cultured adult rat hepatocytes via epidermal growth factor receptors Eur J Pharmacol 431 151 161
    • (2001) Eur J Pharmacol , vol.431 , pp. 151-161
    • Kimura, M.1    Inoue, H.2    Hirabayashi, K.3    Natsume, H.4    Ogihara, M.5
  • 5
    • 37549063079 scopus 로고    scopus 로고
    • In vivo glycyrrhizin accelerates liver regeneration and rapidly lowers serum transaminase activities in 70% partially hepatectomized rats
    • M Kimura T Moro H Motegi H Maruyama M Sekine H Okamoto H Inoue T Sato M Ogihara 2008 In vivo glycyrrhizin accelerates liver regeneration and rapidly lowers serum transaminase activities in 70% partially hepatectomized rats Eur J Pharmacol 579 357 364
    • (2008) Eur J Pharmacol , vol.579 , pp. 357-364
    • Kimura, M.1    Moro, T.2    Motegi, H.3    Maruyama, H.4    Sekine, M.5    Okamoto, H.6    Inoue, H.7    Sato, T.8    Ogihara, M.9
  • 6
    • 40849131005 scopus 로고    scopus 로고
    • Effects of glycyrrhizic acid on cocklebur-induced hepatotoxicity in rat and human hepatocytes
    • J Yin D Li W Hu Q Meng 2008 Effects of glycyrrhizic acid on cocklebur-induced hepatotoxicity in rat and human hepatocytes Phytother Res 22 395 400
    • (2008) Phytother Res , vol.22 , pp. 395-400
    • Yin, J.1    Li, D.2    Hu, W.3    Meng, Q.4
  • 7
    • 38349188607 scopus 로고    scopus 로고
    • Glycyrrhizin attenuates endotoxin-induced acute liver injury after partial hepatectomy in rats
    • B Tang H Qiao F Meng X Sun 2007 Glycyrrhizin attenuates endotoxin-induced acute liver injury after partial hepatectomy in rats Braz J Med Biol Res 40 1637 1646
    • (2007) Braz J Med Biol Res , vol.40 , pp. 1637-1646
    • Tang, B.1    Qiao, H.2    Meng, F.3    Sun, X.4
  • 8
    • 35348911302 scopus 로고    scopus 로고
    • Inhibitory effect of glycyrrhizin on lipopolysaccharide and d-galactosamine-induced mouse liver injury
    • T Yoshida K Abe T Ikeda T Matsushita K Wake T Sato T Sato H Inoue 2007 Inhibitory effect of glycyrrhizin on lipopolysaccharide and d-galactosamine- induced mouse liver injury Eur J Pharmacol 576 136 142
    • (2007) Eur J Pharmacol , vol.576 , pp. 136-142
    • Yoshida, T.1    Abe, K.2    Ikeda, T.3    Matsushita, T.4    Wake, K.5    Sato, T.6    Sato, T.7    Inoue, H.8
  • 9
    • 38349166780 scopus 로고    scopus 로고
    • Glycyrrhizin privents of lipopolysaccharide/d-galactosamine-induced liver injury through down-regulation of matrix metalloproteinase-9 in mice
    • K Abe T Ikeda K Wake T Sato T Sato H Inoue 2008 Glycyrrhizin privents of lipopolysaccharide/d-galactosamine-induced liver injury through down-regulation of matrix metalloproteinase-9 in mice J Pharm Pharmacol 60 91 97
    • (2008) J Pharm Pharmacol , vol.60 , pp. 91-97
    • Abe, K.1    Ikeda, T.2    Wake, K.3    Sato, T.4    Sato, T.5    Inoue, H.6
  • 12
    • 33645227447 scopus 로고    scopus 로고
    • Clinical features of hepatocellular carcinoma that occur after sustained virological response to interferon for chronic hepatitis C
    • M Ikeda S Fujiyama M Tanaka M Sata T Ide H Yatsuhashi H Watanabe 2006 Clinical features of hepatocellular carcinoma that occur after sustained virological response to interferon for chronic hepatitis C J Gastroenterol Hepatol 21 122 128
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 122-128
    • Ikeda, M.1    Fujiyama, S.2    Tanaka, M.3    Sata, M.4    Ide, T.5    Yatsuhashi, H.6    Watanabe, H.7
  • 13
    • 34447298339 scopus 로고    scopus 로고
    • Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, protects liver against carbon tetrachloride-induced oxidative stress in transgenic mice expressing the hepatitis C virus polyprotein
    • I Hidaka K Hino M Korenaga T Gondo S Nishina M Ando M Okuda I Sakaida 2007 Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, protects liver against carbon tetrachloride-induced oxidative stress in transgenic mice expressing the hepatitis C virus polyprotein Liver Int 27 845 853
    • (2007) Liver Int , vol.27 , pp. 845-853
    • Hidaka, I.1    Hino, K.2    Korenaga, M.3    Gondo, T.4    Nishina, S.5    Ando, M.6    Okuda, M.7    Sakaida, I.8
  • 14
    • 0033392097 scopus 로고    scopus 로고
    • Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection
    • TG van Rossum AG Vulto WC Hop SW Schalm 1999 Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection Clin Ther 21 2080 2090
    • (1999) Clin Ther , vol.21 , pp. 2080-2090
    • Van Rossum, T.G.1    Vulto, A.G.2    Hop, W.C.3    Schalm, S.W.4
  • 15
    • 0034886470 scopus 로고    scopus 로고
    • Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C
    • TG van Rossum AG Vulto WC Hop SW Schalm 2001 Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C Am J Gastroenterol 96 2432 2437
    • (2001) Am J Gastroenterol , vol.96 , pp. 2432-2437
    • Van Rossum, T.G.1    Vulto, A.G.2    Hop, W.C.3    Schalm, S.W.4
  • 16
    • 0026643743 scopus 로고
    • A T cell-dependent experimental liver injury in mice inducible by concanavalin A
    • G Tiegs J Hentschel A Wendel 1992 A T cell-dependent experimental liver injury in mice inducible by concanavalin A J Clin Invest 90 196 203
    • (1992) J Clin Invest , vol.90 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.3
  • 18
    • 7044235774 scopus 로고    scopus 로고
    • IFN-gamma/STAT1 acts as a proinflammatory signal in T cell-mediated hepatitis via induction of multiple chemokines and adhesion molecules: A critical role of IRF-1
    • B Jaruga F Hong WH Kim B Gao 2004 IFN-gamma/STAT1 acts as a proinflammatory signal in T cell-mediated hepatitis via induction of multiple chemokines and adhesion molecules: a critical role of IRF-1 Am J Physiol Gastrointest Liver Physiol 287 G1044 G1052
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Jaruga, B.1    Hong, F.2    Kim, W.H.3    Gao, B.4
  • 19
    • 0029994520 scopus 로고    scopus 로고
    • Kinetics and localization of lymphoblasts that proliferate in the mutine liver after Concanavalin A administration
    • S Fujikura H Mizuhara Y Miyazawa H Fujiwara K Kaneda 1996 Kinetics and localization of lymphoblasts that proliferate in the mutine liver after Concanavalin A administration Biomed Res 17 129 139
    • (1996) Biomed Res , vol.17 , pp. 129-139
    • Fujikura, S.1    Mizuhara, H.2    Miyazawa, Y.3    Fujiwara, H.4    Kaneda, K.5
  • 20
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • JS, Beckman WH Koppenol 1996 Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly Am J Physiol 271 C1424 37
    • (1996) Am J Physiol , vol.271 , pp. 1424-37
    • Beckman, J.S.1    Koppenol, W.H.2
  • 21
    • 0031567576 scopus 로고    scopus 로고
    • What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
    • B Halliwell 1997 What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo? FEBS Lett 411 157 160
    • (1997) FEBS Lett , vol.411 , pp. 157-160
    • Halliwell, B.1
  • 22
    • 0030734267 scopus 로고    scopus 로고
    • Nitric oxide in excitable tissues: Physiological roles and diseases
    • KS, Christopherson DS Bredt 1997 Nitric oxide in excitable tissues: physiological roles and diseases J Clin Invest 100 2424 29
    • (1997) J Clin Invest , vol.100 , pp. 2424-29
    • Christopherson, K.S.1    Bredt, D.S.2
  • 23
    • 0030711684 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of endothelial cell dysfunction
    • DG Harrison 1997 Cellular and molecular mechanisms of endothelial cell dysfunction J Clin Invest 100 2153 57
    • (1997) J Clin Invest , vol.100 , pp. 2153-57
    • Harrison, D.G.1
  • 24
    • 0035110655 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice
    • G Sass K Koerber R Bang H Guehring G Tiegs 2001 Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice J Clin Invest 107 439 447
    • (2001) J Clin Invest , vol.107 , pp. 439-447
    • Sass, G.1    Koerber, K.2    Bang, R.3    Guehring, H.4    Tiegs, G.5
  • 26
    • 47649118012 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in the liver is under the control of nuclear factor kappa B in concanavalin A-induced hepatitis
    • XL Ma YH Li JX Gao J Li L Guo CZ Wu 2008 Expression of inducible nitric oxide synthase in the liver is under the control of nuclear factor kappa B in concanavalin A-induced hepatitis J Gastroenterol Hepatol 23 e231 e235
    • (2008) J Gastroenterol Hepatol , vol.23
    • Ma, X.L.1    Li, Y.H.2    Gao, J.X.3    Li, J.4    Guo, L.5    Wu, C.Z.6
  • 27
    • 0019840774 scopus 로고
    • Glycyrrhizin inhibits prostaglandin E2 production by activated peritoneal macrophages from rats
    • K Ohuchi Y Kamada L Levine S Tsurufuji 1981 Glycyrrhizin inhibits prostaglandin E2 production by activated peritoneal macrophages from rats Prostaglandins Med 7 457 463
    • (1981) Prostaglandins Med , vol.7 , pp. 457-463
    • Ohuchi, K.1    Kamada, Y.2    Levine, L.3    Tsurufuji, S.4
  • 29
    • 34547153231 scopus 로고    scopus 로고
    • Diammonium glycyrrhizinate, a component of traditional Chinese medicine Gan-Cao, prevents murine T-cell-mediated fulminant hepatitis in IL-10- and IL-6-dependent manners
    • C Feng H Wang C Yao J Zhang Z Tian 2007 Diammonium glycyrrhizinate, a component of traditional Chinese medicine Gan-Cao, prevents murine T-cell-mediated fulminant hepatitis in IL-10- and IL-6-dependent manners Int Immunopharmacol 7 1292 1298
    • (2007) Int Immunopharmacol , vol.7 , pp. 1292-1298
    • Feng, C.1    Wang, H.2    Yao, C.3    Zhang, J.4    Tian, Z.5
  • 30
    • 0344825278 scopus 로고    scopus 로고
    • Glycyrrhizin enhances interleukin-10 production by liver dendritic cells in mice with hepatitis
    • M Abe F Akbar A Hasebe N Horiike M Onji 2003 Glycyrrhizin enhances interleukin-10 production by liver dendritic cells in mice with hepatitis J Gastroenterol 38 962 967
    • (2003) J Gastroenterol , vol.38 , pp. 962-967
    • Abe, M.1    Akbar, F.2    Hasebe, A.3    Horiike, N.4    Onji, M.5
  • 31
    • 35348993141 scopus 로고    scopus 로고
    • Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice
    • CH Lee SW Park YS Kim SS Kang JA Kim SH Lee SM Lee 2007 Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice Biol Pharm Bull 30 1898 1904
    • (2007) Biol Pharm Bull , vol.30 , pp. 1898-1904
    • Lee, C.H.1    Park, S.W.2    Kim, Y.S.3    Kang, S.S.4    Kim, J.A.5    Lee, S.H.6    Lee, S.M.7
  • 32
    • 0031845303 scopus 로고    scopus 로고
    • Inhibitory effect of glycyrrhizin on NF-kappaB binding activity in CCl4- plus ethanol-induced liver cirrhosis in rats
    • JY Wang JS Guo H Li SL Liu MA Zern 1998 Inhibitory effect of glycyrrhizin on NF-kappaB binding activity in CCl4- plus ethanol-induced liver cirrhosis in rats Liver 18 180 185
    • (1998) Liver , vol.18 , pp. 180-185
    • Wang, J.Y.1    Guo, J.S.2    Li, H.3    Liu, S.L.4    Zern, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.