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Volumn 50, Issue 7, 2009, Pages 1075-1082

B cell activator factor and a proliferation-inducing ligand at the cross-road of chronic lymphocytic leukemia and autoimmunity

Author keywords

Autoimmunity: Responses to self antigen; Cytokine and chemokine biology; Lymphoid leukemia

Indexed keywords

ANTILEUKEMIC AGENT; APRIL PROTEIN; ATACICEPT; B CELL ACTIVATING FACTOR; B CELL MATURATION ANTIGEN; GELONIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RECOMBINANT GELONIN; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 68449091982     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190903013334     Document Type: Review
Times cited : (21)

References (86)
  • 1
    • 67651148468 scopus 로고    scopus 로고
    • Disease-specific complications of chronic lymphocytic leukemia
    • Dearden C. Disease-specific complications of chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2008;2008:450-456.
    • (2008) Hematology Am Soc Hematol Educ Program 2008 , pp. 450-456
    • Dearden, C.1
  • 2
    • 0022443671 scopus 로고
    • Autoimmunity in chronic lymphocytic leukaemia
    • Hamblin TJ, Oscier DG, Young BJ. Autoimmunity in chronic lymphocytic leukaemia. J Clin Pathol 1986;39:713-716.
    • (1986) J Clin Pathol , vol.39 , pp. 713-716
    • Hamblin, T.J.1    Oscier, D.G.2    Young, B.J.3
  • 4
    • 0032555931 scopus 로고    scopus 로고
    • APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth
    • Hahne M, Kataoka T, Schroter M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med 1998;188:1185-1190.
    • (1998) J Exp Med , vol.188 , pp. 1185-1190
    • Hahne, M.1    Kataoka, T.2    Schroter, M.3
  • 5
    • 11844301640 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines
    • Ohata J, Zvaifler NJ, Nishio M, et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. J Immunol 2005;174:864-870.
    • (2005) J Immunol , vol.174 , pp. 864-870
    • Ohata, J.1    Zvaifler, N.J.2    Nishio, M.3
  • 6
    • 0036634390 scopus 로고    scopus 로고
    • BAFF: A fundamental survival factor for B cells
    • Mackay F, Browning JL. BAFF: A fundamental survival factor for B cells. Nat Rev Immunol 2002;2:465-475.
    • (2002) Nat Rev Immunol , vol.2 , pp. 465-475
    • Mackay, F.1    Browning, J.L.2
  • 7
    • 0037644586 scopus 로고    scopus 로고
    • The TNF family members BAFF and APRIL: The growing complexity
    • Mackay F, Ambrose C. The TNF family members BAFF and APRIL: The growing complexity. Cytokine Growth Factor Rev 2003;14:311-324.
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 311-324
    • Mackay, F.1    Ambrose, C.2
  • 9
    • 34247574625 scopus 로고    scopus 로고
    • B cells and the BAFF/APRIL axis: Fast-forward on autoimmunity and signaling
    • Mackay F, Silveira PA, Brink R. B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 2007;19:327-336.
    • (2007) Curr Opin Immunol , vol.19 , pp. 327-336
    • Mackay, F.1    Silveira, P.A.2    Brink, R.3
  • 10
    • 12344329605 scopus 로고    scopus 로고
    • The current status of targeting BAFF/BLyS for autoimmune diseases
    • Ramanujam M, Davidson A. The current status of targeting BAFF/BLyS for autoimmune diseases. Arthritis Res Ther 2004;6:197-202.
    • (2004) Arthritis Res Ther , vol.6 , pp. 197-202
    • Ramanujam, M.1    Davidson, A.2
  • 11
    • 39749174407 scopus 로고    scopus 로고
    • Phase I clinical study of atacicept in patients with relapsed and refractory B-cell non-Hodgkin's lymphoma
    • Ansell SM, Witzig TE, Inwards DJ, et al. Phase I clinical study of atacicept in patients with relapsed and refractory B-cell non-Hodgkin's lymphoma. Clin Cancer Res 2008;14:1105-1110.
    • (2008) Clin Cancer Res , vol.14 , pp. 1105-1110
    • Ansell, S.M.1    Witzig, T.E.2    Inwards, D.J.3
  • 12
    • 44349123977 scopus 로고    scopus 로고
    • A phase Ib trial of atacicept (TACI-Ig) to neutralize APRIL and BLyS in patients with refractory or relapsed B-cell chronic lymphocytic leukemia (B-CLL) [abstract]
    • Abstract 3029
    • Kofler DM, Elter T, Gianella-Borradori A, et al. A phase Ib trial of atacicept (TACI-Ig) to neutralize APRIL and BLyS in patients with refractory or relapsed B-cell chronic lymphocytic leukemia (B-CLL) [abstract]. J Clin Oncol 2007;25:18S. Abstract 3029.
    • (2007) J Clin Oncol , vol.25
    • Kofler, D.M.1    Elter, T.2    Gianella-Borradori, A.3
  • 13
    • 62749116514 scopus 로고    scopus 로고
    • Preclinical support for combination therapy in the treatment of autoimmunity with atacicept
    • Ponce R, Miller D. Preclinical support for combination therapy in the treatment of autoimmunity with atacicept. Toxicol Pathol 2009;37:89-99.
    • (2009) Toxicol Pathol , vol.37 , pp. 89-99
    • Ponce, R.1    Miller, D.2
  • 14
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
    • Schneider P, Mackay F, Steiner V, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999;189:1747-1756.
    • (1999) J Exp Med , vol.189 , pp. 1747-1756
    • Schneider, P.1    Mackay, F.2    Steiner, V.3
  • 16
    • 0036183318 scopus 로고    scopus 로고
    • Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands
    • Liu Y, Xu L, Opalka N, Kappler J, Shu HB, Zhang G. Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell 2002;108:383-394.
    • (2002) Cell , vol.108 , pp. 383-394
    • Liu, Y.1    Xu, L.2    Opalka, N.3    Kappler, J.4    Shu, H.B.5    Zhang, G.6
  • 17
    • 0036221083 scopus 로고    scopus 로고
    • Structural basis of BLyS receptor recognition
    • Oren DA, Li Y, Volovik Y, et al. Structural basis of BLyS receptor recognition. Nat Struct Biol 2002;9:288-292.
    • (2002) Nat Struct Biol , vol.9 , pp. 288-292
    • Oren, D.A.1    Li, Y.2    Volovik, Y.3
  • 18
    • 20244384231 scopus 로고    scopus 로고
    • BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
    • Krumbholz M, Theil D, Derfuss T, et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 2005;201:195-200.
    • (2005) J Exp Med , vol.201 , pp. 195-200
    • Krumbholz, M.1    Theil, D.2    Derfuss, T.3
  • 19
    • 34447331962 scopus 로고    scopus 로고
    • Expression of B-cell activating factor of the tumour necrosis factor family (BAFF) in T cells in active systemic lupus erythematosus: The role of BAFF in T cell-dependent B cell pathogenic autoantibody production
    • Morimoto S, Nakano S, Watanabe T, et al. Expression of B-cell activating factor of the tumour necrosis factor family (BAFF) in T cells in active systemic lupus erythematosus: The role of BAFF in T cell-dependent B cell pathogenic autoantibody production. Rheumatology (Oxford) 2007;46:1083-1086.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 1083-1086
    • Morimoto, S.1    Nakano, S.2    Watanabe, T.3
  • 20
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B-lymphocyte stimulator from myeloid cells
    • Nardelli B, Belvedere O, Roschke V, et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 2001;97:198-204.
    • (2001) Blood , vol.97 , pp. 198-204
    • Nardelli, B.1    Belvedere, O.2    Roschke, V.3
  • 21
    • 0037415599 scopus 로고    scopus 로고
    • G-CSF-stimulated neutrophils are a prominent source of functional BLyS
    • Scapini P, Nardelli B, Nadali G, et al. G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med 2003;197:297-302.
    • (2003) J Exp Med , vol.197 , pp. 297-302
    • Scapini, P.1    Nardelli, B.2    Nadali, G.3
  • 22
    • 0038142395 scopus 로고    scopus 로고
    • Macrophageand dendritic cell-dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF
    • Craxton A, Magaletti D, Ryan EJ, Clark EA. Macrophageand dendritic cell-dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF. Blood 2003;101:4464-4471.
    • (2003) Blood , vol.101 , pp. 4464-4471
    • Craxton, A.1    Magaletti, D.2    Ryan, E.J.3    Clark, E.A.4
  • 24
    • 33747837100 scopus 로고    scopus 로고
    • BAFF, APRIL and their receptors: Structure, function and signaling
    • Bossen C, Schneider P. BAFF, APRIL and their receptors: Structure, function and signaling. Semin Immunol 2006;18: 263-275.
    • (2006) Semin Immunol , vol.18 , pp. 263-275
    • Bossen, C.1    Schneider, P.2
  • 26
    • 0242684718 scopus 로고    scopus 로고
    • Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
    • Kim HM, Yu KS, Lee ME, et al. Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation. Nat Struct Biol 2003;10:342-348.
    • (2003) Nat Struct Biol , vol.10 , pp. 342-348
    • Kim, H.M.1    Yu, K.S.2    Lee, M.E.3
  • 27
    • 0039792391 scopus 로고    scopus 로고
    • NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
    • von Bulow GU, Bram RJ. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. Science 1997;278:138-141.
    • (1997) Science , vol.278 , pp. 138-141
    • von Bulow, G.U.1    Bram, R.J.2
  • 28
    • 0034634625 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
    • Wu Y, Bressette D, Carrell JA, et al. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J Biol Chem 2000;275:35478-35485.
    • (2000) J Biol Chem , vol.275 , pp. 35478-35485
    • Wu, Y.1    Bressette, D.2    Carrell, J.A.3
  • 29
    • 33751267944 scopus 로고    scopus 로고
    • BAFF: A regulatory cytokine of B lymphocytes involved in autoimmunity and lymphoid cancer
    • Reyes SL, Leon BF, Rozas VM, Gonzalez JP, Naves PR. BAFF: A regulatory cytokine of B lymphocytes involved in autoimmunity and lymphoid cancer. Rev Med Chil 2006;134:1175-1184.
    • (2006) Rev Med Chil , vol.134 , pp. 1175-1184
    • Reyes, S.L.1    Leon, B.F.2    Rozas, V.M.3    Gonzalez, J.P.4    Naves, P.R.5
  • 30
    • 0026703224 scopus 로고
    • A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma
    • Laabi Y, Gras MP, Carbonnel F, et al. A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma. EMBO J 1992;11:3897-3904.
    • (1992) EMBO J , vol.11 , pp. 3897-3904
    • Laabi, Y.1    Gras, M.P.2    Carbonnel, F.3
  • 31
    • 0347285357 scopus 로고    scopus 로고
    • BCMA is essential for the survival of long-lived bone marrow plasma cells
    • O'Connor BP, Raman VS, Erickson LD, et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 2004;199:91-98.
    • (2004) J Exp Med , vol.199 , pp. 91-98
    • O'Connor, B.P.1    Raman, V.S.2    Erickson, L.D.3
  • 32
    • 38849104447 scopus 로고    scopus 로고
    • Regulated expression of BAFF-binding receptors during human B cell differentiation
    • Darce JR, Arendt BK, Wu X, Jelinek DF. Regulated expression of BAFF-binding receptors during human B cell differentiation. J Immunol 2007;179:7276-7286.
    • (2007) J Immunol , vol.179 , pp. 7276-7286
    • Darce, J.R.1    Arendt, B.K.2    Wu, X.3    Jelinek, D.F.4
  • 33
    • 33846351257 scopus 로고    scopus 로고
    • To switch or not to switch - the opposing roles of TACI in terminal B cell differentiation
    • Salzer U, Jennings S, Grimbacher B. To switch or not to switch - the opposing roles of TACI in terminal B cell differentiation. Eur J Immunol 2007;37:17-20.
    • (2007) Eur J Immunol , vol.37 , pp. 17-20
    • Salzer, U.1    Jennings, S.2    Grimbacher, B.3
  • 34
    • 0034600787 scopus 로고    scopus 로고
    • TACI is a TRAFinteracting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation
    • Xia XZ, Treanor J, Senaldi G, et al. TACI is a TRAFinteracting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation. J Exp Med 2000;192:137-143.
    • (2000) J Exp Med , vol.192 , pp. 137-143
    • Xia, X.Z.1    Treanor, J.2    Senaldi, G.3
  • 35
    • 0035007222 scopus 로고    scopus 로고
    • B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses
    • Xu S, Lam KP. B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses. Mol Cell Biol 2001;21:4067-4074.
    • (2001) Mol Cell Biol , vol.21 , pp. 4067-4074
    • Xu, S.1    Lam, K.P.2
  • 36
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice
    • YanM,Wang H, Chan B, et al. Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2001;2:638-643.
    • (2001) Nat Immunol , vol.2 , pp. 638-643
    • YanM1    Wang, H.2    Chan, B.3
  • 37
    • 0034613222 scopus 로고    scopus 로고
    • T-Independent immune response: New aspects of B cell biology
    • Fagarasan S, Honjo T. T-Independent immune response: New aspects of B cell biology. Science 2000;290:89-92.
    • (2000) Science , vol.290 , pp. 89-92
    • Fagarasan, S.1    Honjo, T.2
  • 38
    • 12344297875 scopus 로고    scopus 로고
    • TACI and BAFF-R mediate isotype switching in B cells
    • Castigli E, Wilson SA, Scott S, et al. TACI and BAFF-R mediate isotype switching in B cells. J Exp Med 2005;201:35-39.
    • (2005) J Exp Med , vol.201 , pp. 35-39
    • Castigli, E.1    Wilson, S.A.2    Scott, S.3
  • 39
    • 23044463627 scopus 로고    scopus 로고
    • TACI is mutant in common variable immunodeficiency and IgA deficiency
    • Castigli E, Wilson SA, Garibyan L, et al. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat Genet 2005;37:829-834.
    • (2005) Nat Genet , vol.37 , pp. 829-834
    • Castigli, E.1    Wilson, S.A.2    Garibyan, L.3
  • 40
    • 38849104447 scopus 로고    scopus 로고
    • Regulated expression of BAFF-binding receptors during human B cell differentiation
    • Darce JR, Arendt BK, Wu X, Jelinek DF. Regulated expression of BAFF-binding receptors during human B cell differentiation. J Immunol 2007;179:7276-7286.
    • (2007) J Immunol , vol.179 , pp. 7276-7286
    • Darce, J.R.1    Arendt, B.K.2    Wu, X.3    Jelinek, D.F.4
  • 41
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-κB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G, Karin M. The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol 2004;25:280-288.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 42
    • 85047692516 scopus 로고    scopus 로고
    • Signalling pathways of the TNF superfamily: A double-edged sword
    • Aggarwal BB. Signalling pathways of the TNF superfamily: A double-edged sword. Nat Rev Immunol 2003;3:745-756.
    • (2003) Nat Rev Immunol , vol.3 , pp. 745-756
    • Aggarwal, B.B.1
  • 43
    • 33750494135 scopus 로고    scopus 로고
    • Rescue of TRAF3-null mice by p100 NF-κB deficiency
    • He JQ, Zarnegar B, Oganesyan G, et al. Rescue of TRAF3-null mice by p100 NF-κB deficiency. J Exp Med 2006;203: 2413-2418.
    • (2006) J Exp Med , vol.203 , pp. 2413-2418
    • He, J.Q.1    Zarnegar, B.2    Oganesyan, G.3
  • 44
    • 0030292777 scopus 로고    scopus 로고
    • Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
    • Xu Y, Cheng G, Baltimore D. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity 1996;5:407-415.
    • (1996) Immunity , vol.5 , pp. 407-415
    • Xu, Y.1    Cheng, G.2    Baltimore, D.3
  • 45
    • 14544286868 scopus 로고    scopus 로고
    • TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/ 5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs
    • Hauer J, Puschner S, Ramakrishnan P, et al. TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/ 5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs. Proc Natl Acad Sci USA 2005;102:2874-2879.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2874-2879
    • Hauer, J.1    Puschner, S.2    Ramakrishnan, P.3
  • 46
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • Thien M, Phan TG, Gardam S, et al. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 2004;20:785-798.
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3
  • 47
    • 33845864446 scopus 로고    scopus 로고
    • High-level serum B-cell activating factor and promoter polymorphisms in patients with idiopathic thrombocytopenic purpura
    • Emmerich F, Bal G, Barakat A, et al. High-level serum B-cell activating factor and promoter polymorphisms in patients with idiopathic thrombocytopenic purpura. Br J Haematol 2007; 136:309-314.
    • (2007) Br J Haematol , vol.136 , pp. 309-314
    • Emmerich, F.1    Bal, G.2    Barakat, A.3
  • 48
    • 0012589457 scopus 로고    scopus 로고
    • Analysis on the association of human BLYS (BAFF, TNFSF13B) polymorphisms with systemic lupus erythematosus and rheumatoid arthritis
    • Kawasaki A, Tsuchiya N, Fukazawa T, Hashimoto H, Tokunaga K. Analysis on the association of human BLYS (BAFF, TNFSF13B) polymorphisms with systemic lupus erythematosus and rheumatoid arthritis. Genes Immun 2002;3:424-429.
    • (2002) Genes Immun , vol.3 , pp. 424-429
    • Kawasaki, A.1    Tsuchiya, N.2    Fukazawa, T.3    Hashimoto, H.4    Tokunaga, K.5
  • 49
    • 0141615882 scopus 로고    scopus 로고
    • A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus
    • Koyama T, Tsukamoto H, Masumoto K, et al. A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus. Rheumatology (Oxford) 2003;42:980-985.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 980-985
    • Koyama, T.1    Tsukamoto, H.2    Masumoto, K.3
  • 50
    • 21344441005 scopus 로고    scopus 로고
    • Raised serum APRIL levels in patients with systemic lupus erythematosus
    • Koyama T, Tsukamoto H, Miyagi Y, et al. Raised serum APRIL levels in patients with systemic lupus erythematosus. Ann Rheum Dis 2005;64:1065-1067.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1065-1067
    • Koyama, T.1    Tsukamoto, H.2    Miyagi, Y.3
  • 52
    • 0037386743 scopus 로고    scopus 로고
    • Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis
    • Tan SM, Xu D, Roschke V, et al. Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum 2003;48:982-992.
    • (2003) Arthritis Rheum , vol.48 , pp. 982-992
    • Tan, S.M.1    Xu, D.2    Roschke, V.3
  • 53
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
    • Groom J, Kalled SL, Cutler AH, et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J Clin Invest 2002;109:59-68.
    • (2002) J Clin Invest , vol.109 , pp. 59-68
    • Groom, J.1    Kalled, S.L.2    Cutler, A.H.3
  • 54
    • 34547631106 scopus 로고    scopus 로고
    • Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator
    • Hever A, Roth RB, Hevezi P, et al. Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator. Proc Natl Acad Sci USA 2007;104: 12451-12456.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12451-12456
    • Hever, A.1    Roth, R.B.2    Hevezi, P.3
  • 55
    • 47549101395 scopus 로고    scopus 로고
    • Serum BAFF expression in patients with myasthenia gravis
    • Kim JY, Yang Y, Moon JS, et al. Serum BAFF expression in patients with myasthenia gravis. J Neuroimmunol 2008;199: 151-154.
    • (2008) J Neuroimmunol , vol.199 , pp. 151-154
    • Kim, J.Y.1    Yang, Y.2    Moon, J.S.3
  • 56
    • 0036940946 scopus 로고    scopus 로고
    • Levels of BAFF in serum in primary biliary cirrhosis and autoimmune diabetes
    • Mackay IR, Groom J, Mackay CR. Levels of BAFF in serum in primary biliary cirrhosis and autoimmune diabetes. Autoimmunity 2002;35:551-553.
    • (2002) Autoimmunity , vol.35 , pp. 551-553
    • Mackay, I.R.1    Groom, J.2    Mackay, C.R.3
  • 57
    • 33646453628 scopus 로고    scopus 로고
    • Updates from B Cell trials: Efficacy
    • Cohen SB. Updates from B Cell trials: Efficacy. J Rheumatol Suppl 2006;77:12-17.
    • (2006) J Rheumatol Suppl , vol.77 , pp. 12-17
    • Cohen, S.B.1
  • 58
    • 9144220762 scopus 로고    scopus 로고
    • Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway
    • Kern C, Cornuel JF, Billard C, et al. Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 2004;103:679-688.
    • (2004) Blood , vol.103 , pp. 679-688
    • Kern, C.1    Cornuel, J.F.2    Billard, C.3
  • 59
    • 49349099119 scopus 로고    scopus 로고
    • Serum BAFF predicts prognosis better than APRIL in diffuse large B-cell lymphoma patients treated with rituximab plus CHOP chemotherapy
    • Kim SJ, Lee SJ, Choi IY, et al. Serum BAFF predicts prognosis better than APRIL in diffuse large B-cell lymphoma patients treated with rituximab plus CHOP chemotherapy. Eur J Haematol 2008;81:177-184.
    • (2008) Eur J Haematol , vol.81 , pp. 177-184
    • Kim, S.J.1    Lee, S.J.2    Choi, I.Y.3
  • 60
    • 34249709065 scopus 로고    scopus 로고
    • Paracrine promotion of tumor development by the TNF ligand APRIL in Hodgkin's disease
    • Schwaller J, Went P, Matthes T, et al. Paracrine promotion of tumor development by the TNF ligand APRIL in Hodgkin's disease. Leukemia 2007;21:1324-1327.
    • (2007) Leukemia , vol.21 , pp. 1324-1327
    • Schwaller, J.1    Went, P.2    Matthes, T.3
  • 61
    • 33845969135 scopus 로고    scopus 로고
    • Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness
    • Schwaller J, Schneider P, Mhawech-Fauceglia P, et al. Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness. Blood 2007;109:331-338.
    • (2007) Blood , vol.109 , pp. 331-338
    • Schwaller, J.1    Schneider, P.2    Mhawech-Fauceglia, P.3
  • 62
    • 33846238425 scopus 로고    scopus 로고
    • Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL
    • Chiu A, Xu W, He B, et al. Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL. Blood 2007;109:729-739.
    • (2007) Blood , vol.109 , pp. 729-739
    • Chiu, A.1    Xu, W.2    He, B.3
  • 63
    • 3142671331 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
    • Ng LG, Sutherland AP, Newton R, et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 2004;173:807.
    • (2004) J Immunol , vol.173 , pp. 807
    • Ng, L.G.1    Sutherland, A.P.2    Newton, R.3
  • 64
    • 0036141462 scopus 로고    scopus 로고
    • BLyS and BLyS receptor expression in non-Hodgkin's lymphoma
    • Briones J, Timmerman JM, Hilbert DM, Levy R. BLyS and BLyS receptor expression in non-Hodgkin's lymphoma. Exp Hematol 2002;30:135-141.
    • (2002) Exp Hematol , vol.30 , pp. 135-141
    • Briones, J.1    Timmerman, J.M.2    Hilbert, D.M.3    Levy, R.4
  • 65
    • 1342282154 scopus 로고    scopus 로고
    • Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL
    • He B, Chadburn A, Jou E, et al. Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. J Immunol 2004;172:3268-3279.
    • (2004) J Immunol , vol.172 , pp. 3268-3279
    • He, B.1    Chadburn, A.2    Jou, E.3
  • 66
    • 11144355586 scopus 로고    scopus 로고
    • BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
    • Moreaux J, Legouffe E, Jourdan E, et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 2004;103:3148-3157.
    • (2004) Blood , vol.103 , pp. 3148-3157
    • Moreaux, J.1    Legouffe, E.2    Jourdan, E.3
  • 67
    • 33644913405 scopus 로고    scopus 로고
    • Elevated serum Blymphocyte stimulator levels in patients with familial lymphoproliferative disorders
    • Novak AJ, Grote DM, Ziesmer SC, et al. Elevated serum Blymphocyte stimulator levels in patients with familial lymphoproliferative disorders. J Clin Oncol 2006;24:983-987.
    • (2006) J Clin Oncol , vol.24 , pp. 983-987
    • Novak, A.J.1    Grote, D.M.2    Ziesmer, S.C.3
  • 68
  • 69
    • 4944262288 scopus 로고    scopus 로고
    • Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: Correlation with disease activity and patient outcome
    • Novak AJ, Grote DM, Stenson M, et al. Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: Correlation with disease activity and patient outcome. Blood 2004;104:2247-2253.
    • (2004) Blood , vol.104 , pp. 2247-2253
    • Novak, A.J.1    Grote, D.M.2    Stenson, M.3
  • 70
    • 0242495542 scopus 로고    scopus 로고
    • EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching
    • He B, Raab-Traub N, Casali P, Cerutti A. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J Immunol 2003;171:5215-5224.
    • (2003) J Immunol , vol.171 , pp. 5215-5224
    • He, B.1    Raab-Traub, N.2    Casali, P.3    Cerutti, A.4
  • 71
    • 55049131371 scopus 로고    scopus 로고
    • Increased serum BAFF (B-cell activating factor of the TNF family) level is a peculiar feature associated with familial chronic lymphocytic leukemia
    • Molica S, Digiesi G, Mauro F, et al. Increased serum BAFF (B-cell activating factor of the TNF family) level is a peculiar feature associated with familial chronic lymphocytic leukemia. Leuk Res 2009;33:162-165.
    • (2009) Leuk Res , vol.33 , pp. 162-165
    • Molica, S.1    Digiesi, G.2    Mauro, F.3
  • 72
    • 36348943503 scopus 로고    scopus 로고
    • APRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: Prognostic relevance of APRIL for survival
    • Planelles L, Castillo-Gutierrez S, Medema JP, et al. APRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: Prognostic relevance of APRIL for survival. Haematologica 2007;92:1284-1285.
    • (2007) Haematologica , vol.92 , pp. 1284-1285
    • Planelles, L.1    Castillo-Gutierrez, S.2    Medema, J.P.3
  • 73
    • 0037108558 scopus 로고    scopus 로고
    • Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: A mechanism for survival
    • Novak AJ, Bram RJ, Kay NE, Jelinek DF. Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: A mechanism for survival. Blood 2002;100: 2973-2979.
    • (2002) Blood , vol.100 , pp. 2973-2979
    • Novak, A.J.1    Bram, R.J.2    Kay, N.E.3    Jelinek, D.F.4
  • 74
    • 0242298176 scopus 로고    scopus 로고
    • Role of the microenvironment in chronic lymphocytic leukaemia
    • Caligaris-Cappio F. Role of the microenvironment in chronic lymphocytic leukaemia. Br J Haematol 2003;123:380-388.
    • (2003) Br J Haematol , vol.123 , pp. 380-388
    • Caligaris-Cappio, F.1
  • 75
    • 23044514711 scopus 로고    scopus 로고
    • Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1a
    • Nishio M, Endo T, Tsukada N, et al. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1a. Blood 2005;106:1012-1020.
    • (2005) Blood , vol.106 , pp. 1012-1020
    • Nishio, M.1    Endo, T.2    Tsukada, N.3
  • 76
    • 0034667624 scopus 로고    scopus 로고
    • Blood-derived nurselike cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
    • Burger JA, Tsukada N, Burger M, et al. Blood-derived nurselike cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 2000;96:2655-2663.
    • (2000) Blood , vol.96 , pp. 2655-2663
    • Burger, J.A.1    Tsukada, N.2    Burger, M.3
  • 77
    • 33846258010 scopus 로고    scopus 로고
    • BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-κB pathway
    • Endo T, Nishio M, Enzler T, et al. BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-κB pathway. Blood 2007;109:703-710.
    • (2007) Blood , vol.109 , pp. 703-710
    • Endo, T.1    Nishio, M.2    Enzler, T.3
  • 78
    • 0028822481 scopus 로고
    • Chronic lymphocytic leukemia
    • Rozman C, Montserrat E. Chronic lymphocytic leukemia. N Engl J Med 1995;333:1052-1057.
    • (1995) N Engl J Med , vol.333 , pp. 1052-1057
    • Rozman, C.1    Montserrat, E.2
  • 79
    • 33846944718 scopus 로고    scopus 로고
    • Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity
    • Smit LA, Hallaert DY, Spijker R, et al. Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity. Blood 2007;109:1660-1668.
    • (2007) Blood , vol.109 , pp. 1660-1668
    • Smit, L.A.1    Hallaert, D.Y.2    Spijker, R.3
  • 80
    • 77952072561 scopus 로고    scopus 로고
    • Molecular basis of proliferation/ survival and migration of CLL in peripheral blood, bone marrow and lymph nodes [abstract]
    • Abstract 546
    • Mittal AK, Iqbal J, Nordgren TM, et al. Molecular basis of proliferation/ survival and migration of CLL in peripheral blood, bone marrow and lymph nodes [abstract]. Blood 2008;112. Abstract 546.
    • (2008) Blood , pp. 112
    • Mittal, A.K.1    Iqbal, J.2    Nordgren, T.M.3
  • 81
    • 68449090096 scopus 로고    scopus 로고
    • BAFF Accelerates development of chronic lymphocytic leukemia in TCL1 transgenic mice [abstract]
    • Abstract 1117
    • Enzler T, Widhopf GF, Lee J, et al. BAFF Accelerates development of chronic lymphocytic leukemia in TCL1 transgenic mice [abstract]. Blood 2007;110. Abstract 1117.
    • (2007) Blood , pp. 110
    • Enzler, T.1    Widhopf, G.F.2    Lee, J.3
  • 82
    • 68449095025 scopus 로고    scopus 로고
    • Constitutive Baff signalling plays a key role in CLL development by promoting tumor cell survival [abstract]
    • Abstract 28
    • Enzler T, Zhang W, Kater AP, et al. Constitutive Baff signalling plays a key role in CLL development by promoting tumor cell survival [abstract]. Blood 2008;112. Abstract 28.
    • (2008) Blood , pp. 112
    • Enzler, T.1    Zhang, W.2    Kater, A.P.3
  • 84
    • 57349186143 scopus 로고    scopus 로고
    • Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgVH genes
    • Vanura K, Le T, Esterbauer H, et al. Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgVH genes. Haematologica 2008;93:1912-1916.
    • (2008) Haematologica , vol.93 , pp. 1912-1916
    • Vanura, K.1    Le, T.2    Esterbauer, H.3
  • 85
    • 43249104448 scopus 로고    scopus 로고
    • Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: A pooled analysis within the InterLymph Consortium
    • Ekstrom SK, Vajdic CM, Falster M, et al. Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: A pooled analysis within the InterLymph Consortium. Blood 2008;111:4029-4038.
    • (2008) Blood , vol.111 , pp. 4029-4038
    • Ekstrom, S.K.1    Vajdic, C.M.2    Falster, M.3
  • 86
    • 33947274774 scopus 로고    scopus 로고
    • The growth factor fusion construct containing B-lymphocyte stimulator (BLyS) and the toxin rGel induces apoptosis specifically in BAFF-R-positive CLL cells
    • Nimmanapalli R, Lyu MA, Du M, et al. The growth factor fusion construct containing B-lymphocyte stimulator (BLyS) and the toxin rGel induces apoptosis specifically in BAFF-R-positive CLL cells. Blood 2007;109:2557-2564.
    • (2007) Blood , vol.109 , pp. 2557-2564
    • Nimmanapalli, R.1    Lyu2    MA, D.M.3


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