Prevention and reversal of morphine tolerance by the analgesic neuroactive steroid alphadolone

Pain Medicine

Volumn 10, Issue 5, 2009, Pages 890-901

  Goodchild, Colin S ^a,c   Kolosov, Anton ^a   Geng, Licheng ^b   Winter, Lara L ^b   Nadeson, Ray ^b  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c NONE   (Australia)

Author keywords

Alphadolone; Alphaxalone; Morphine tolerance; Neuroactive steroid; Opioid tolerance

Indexed keywords

ALFADOLONE ACETATE; ALFAXALONE; CREMOPHOR; MORPHINE; PLACEBO;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG TOLERANCE; EMULSION; LATENT PERIOD; MALE; NOCICEPTION; NONHUMAN; RAT; SEDATION; SUSTAINED RELEASE FORMULATION;

ANALGESICS; ANALGESICS, OPIOID; ANIMALS; DELAYED-ACTION PREPARATIONS; DRUG TOLERANCE; EMULSIONS; HYPNOTICS AND SEDATIVES; MALE; MORPHINE; PAIN MEASUREMENT; PREGNANEDIONES; RATS; RATS, WISTAR;

EID: 68349131608     PISSN: 15262375     EISSN: 15264637     Source Type: Journal    
DOI: 10.1111/j.1526-4637.2009.00663.x     Document Type: Article

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