Mrz 2/579, a fast kinetic NMDA channel blocker, reduces the development of morphine tolerance in awake rats

Pain

Volumn 91, Issue 3, 2001, Pages 201-207

  Houghton, Andrea K ^a,c   Parsons, Chris G ^b   Headley, P Max ^a  

^a SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

^b MERZ PHARMACEUTICALS GMBH   (Germany)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Morphine tolerance; Mrz 2 579; NMDA channel blocker

Indexed keywords

HALOTHANE; KETAMINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NERAMEXANE;

ANALGESIA; ANESTHESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG HALF LIFE; DRUG INFUSION; MALE; MINIPUMP; MORPHINE TOLERANCE; MOTOR COORDINATION; NONHUMAN; PRIORITY JOURNAL; RAT; WITHDRAWAL REFLEX;

ANALGESICS, OPIOID; ANIMALS; CYCLOPENTANES; DRUG TOLERANCE; MALE; MORPHINE; NEUROPROTECTIVE AGENTS; PAIN; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM CHLORIDE; SUBSTANCE WITHDRAWAL SYNDROME; WAKEFULNESS;

EID: 0035087021     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(00)00428-0     Document Type: Article

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