N-Methyl-D-aspartate receptor antagonist MK-801 attenuates morphine tolerance and associated glial fibrillary acid protein up-regulation: A proteomic approach

Acta Anaesthesiologica Scandinavica

Volumn 52, Issue 4, 2008, Pages 499-508

  Wen, Z H ^a   Wu, G J ^b,c   Hsu, L C ^d   Chen, W F ^e   Chen, J Y ^b   Shui, H A ^f   Chou, A K ^e   Wong, C S ^g  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d ACADEMIA SINICA   (Taiwan)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^g TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

GFAP; Morphine tolerance; NMDA; Proteomics

Indexed keywords

DIZOCILPINE; GLIAL FIBRILLARY ACIDIC PROTEIN; MORPHINE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG INHIBITION; GEL ELECTROPHORESIS; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; RAT; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; DIZOCILPINE MALEATE; DRUG TOLERANCE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EXCITATORY AMINO ACID ANTAGONISTS; GLIAL FIBRILLARY ACIDIC PROTEIN; MALE; MASS SPECTROMETRY; MORPHINE; NOCICEPTORS; PROTEOMICS; RATS; RATS, WISTAR; SODIUM CHLORIDE; SPINAL CORD; TIME FACTORS; UP-REGULATION;

EID: 40849097796     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2008.01605.x     Document Type: Article

References (45)

1. Trujillo KA, Akil H. Inhibition of morophine tolerance and dependence by the NMDA receptor antagonist MK-801. Science 1991 251 : 85 7.
2. Gutstein HB, Trujillo KA. MK-801 inhibits the development of morphine tolerance at spinal sites. Brain Res 1993 626 : 332 4.
3. Kest B, Mogil JS, Shamgar BE et al. The NMDA receptor antagonist MK-801 protects against the development of morphine tolerance after intrathecal administration. Proc West Pharmacol Soc 1993 36 : 307 10.
4. Wong CS, Cherng CH, Luk HN et al. Effect of NMDA receptor antagonists on inhibition of morphine tolerance in rats: binding of μ-opioid receptors. Eur J Pharmacol 1996 297 : 27 33.
5. Wong CS, Chang YC, Yeh CC et al. Loss of intrathecal morphine analgesia in terminal cancer patients is associated with high levels of excitatory amino acids in the CSF. Can J Anaesth 2002 49 : 561 5.
6. Wen ZH, Chang YC, Cherng CH et al. Increasing of intrathecal CSF excitatory amino acids concentration following morphine challenge in morphine-tolerant rats. Brain Res 2004 995 : 253 9.
7. Wen ZH, Wu GJ, Chang YC et al. Dexamethasone modulates the development of morphine tolerance and expression of glutamate transporters in rats. Neuroscience 2005 133 : 807 17.
8. Zhu H, Barr GA. Opiate withdrawal during development: Are NMDA receptors indispensable? Trends Pharmacol Sci 2001 22 : 404 8.
9. Mao J. NMDA and opioid receptors: their interactions in antinociception, tolerance and neuroplasticity. Brain Res Rev 1999 30 : 289 304.
10. Charles AC, Hales TG. From inhibition to excitation: functional effects of interaction between opioid receptors. Life Sci 2004 76 : 479 85.
11. Corbett AD, Henderson G, McKnight AT et al. 75 years of opioid research: the exciting but vain quest fro the Holy Grail. Br J Pharmaco 2006 147 : 153 62.
12. Rohlffc C, Southan C. Proteomic approaches to central nervous system disorders. Curr Opin Mol Ther 2002 4 : 251 8.
13. Yaksh TL, Rudy TA. Chronic catheterization of spinal subarachnoid space. Physiol Behav 1976 17 : 1031 6.
14. Granados-Soto V, Kalcheva I, Hua X et al. Spinal PKC activity and expression: role in tolerance produced by continuous spinal morphine infusion. Pain 2000 85 : 395 404.
15. Lowry DH, Rosebrough NJ, Farr AL et al. Protein measurement with the folin phenol reagent. J Biol Chem 1951 193 : 265 75.
16. Eng LF, Vanderheagen JJ, Bignami A et al. An acidic protein isolated from fibrous astrocytes. Brain Res 1971 28 : 351 4.
17. Seifert G, Schilling K, Steinhauser C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat Rev Neurosci 2006 7 : 194 206.
18. Kanninen K, Goldsteins G, Auriola S et al. Glycosylation of changes in Alzheimer's disease as revealed by a proteomics approach. Neurosci Lett 2004 367 : 235 40.
19. Reeves SA, Helman LJ, Allison A et al. Molecular cloning and primary structure of human glial fibrillary acidic protein. Proc Natl Acad Sci USA 1989 86 : 5178 82.
20. Isaacs A, Baker M, Wavrant-De VF et al. Determination of the gene structure of human GFAP and absence of coding region mutations associated with frontotemporal dementia with parkinsonism linked to chromosome 17. Genomics 1998 51 : 152 4.
21. Feinstein DL, Weinmaster GA, Milner RJ. Isolation of cDNA clones encoding rat glial fibrillary acidic protein: expression in astrocytes and in Schwann cells. J. Neurosci Res 1992 32 : 1 14.
22. Zelenika D, Grima B, Brenner M et al. A novel glial fibrillary acidic protein mRNA lacking exon 1. Mol Brain Res 1995 30 : 251 8.
23. Galea E, Dupouey P, Feinstein DL. Glial fibrillary acidic protein mRNAisotypes: expression in vitro and in vivo. J Neurosci Res 1995 41 : 452 61.
24. Nielsen AL, Holm IE, Johansen M et al. A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins. J Biol Chem 2002 277 : 29983 91.
25. Bongcam-Rudloff E, Nister M, Betsholtz C et al. Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes. Cancer Res 1991 51 : 1553 60.
26. Lubec G, Krapfenbauer K, Fountoulakis M. Proteomic in brain research: potentials and limitations. Pro Neurobiol 2003 69 : 193 211.
27. Noetzel MJ. Phosphorylation of the glial fibrillary acidic protein. J Neurosci Res 1990 27 : 184 92.
28. Kosako H, Amano M, Yanagida M et al. Phosphorylation of glial fibrillary acidic protein at the same site by cleavage furrow kinase and rho-associated kinase. J Biol Chem 1997 272 : 10333 6.
29. Harrison B, Mobley PL. Protein phosphorylation in astrocytes mediated by protein kinase C: comparison with phosphorylation by cyclic AMP-dependent protein kinase. J Neurochem 1989 53 : 1245 51.
30. 2+/ calmodulin dependent protein kinase II and phosphorylation of intermediate filament proteins by stimulation of glutamate receptors in cultured rat cortical astrocytes. J Biol Chem 1994 269 : 5428 39.
31. Rodnight R, Goncalves CA, Wofchuk ST et al. Control of the phosphorylation of the astrocyte marker glial fibrillary acdic protein (GFAP) in the immature rat hippocampus by glutamate and calcium ions: possible key factor in astrocytic plasticity. Braz J Med Bio Res 1997 30 : 325 38.
32. Mayer DJ, Mao J, Holt J et al. Cellular mechanism of neuropathic pain, morphine tolerance, and their interaction. Proc Natl Acad Sci USA 1999 96 : 7731 6.
33. 2+/ calmodulin-dependent protein kinase II alpha during chronic morphine exposure. Neuroscience 2004 123 : 769 75.
34. Araque A, Sanzgiri RP, Parpura V et al. Astrocyte-induced modulation of synaptic transmission. Can J Physiol Pharmacol 1999 77 : 699 706.
35. Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends Neurosci 2001 24 : 450 5.
36. Watkins LR, Milligan ED, Maier SF. Spinal cord glia: new players in pain. Pain 2001 93 : 201 5.
37. Winkelstein BA, Rutkowski MD, Sweitzer SM et al. Nerve injury proximal or distal to the DRG induces similar spinal glial activation an selective cytokine expression but differential behavioral responses to pharmacological treatment. J Comp Neurol 2001 439 : 127 39.
38. Garrison CJ, Dougherty PM, Kajander KC et al. Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury. Brain Res 1991 565 : 1 7.
39. Garrison CJ, Dougherty PM, Carlton SM. GFAP expression in lumbar spinal cord of naive and neuropathic rats treated with MK-80. Exp Neurol 1994 129 : 237 43.
40. Mayer DJ, Mao J, Holt J et al. Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions. Proc Natl Acad Sci USA 1999 96 : 7731 6.
41. Raghavendra V, Rutkowski MD, DeLeo JA. The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. J Neurosci 2002 22 : 9980 9.
42. Song P, Zhao ZQ. The involvement of glial of cells in the development of morphine tolerance. Neurosci Res 2001 39 : 281 6.
43. Meller ST, Dykstra C, Grzybycki D et al. The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat. Neuropharmacology 1994 33 : 1471 8.
44. Watkins LR, Martin D, Ulrich P et al. Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat. Pain 1997 71 : 225 35.
45. Shui HA, Ho ST, Wang JJ et al. Proteomic analysis of spinal protein expression in rats exposed to repeated intrathecal morphine injection. Proteomic 2007 7 : 796 803.