Improved efficacy of DNA vaccination against prostate carcinoma by boosting with recombinant protein vaccine and by introduction of a novel adjuvant epitope

Vaccine

Volumn 27, Issue 39, 2009, Pages 5411-5418

  Lu, Yong ^a,d   Ouyang, Kedong ^a   Fang, Jing ^b   Zhang, Huiyong ^a,c   Wu, Guojun ^a   Ma, Yanjun ^a   Zhang, Yu ^a   Hu, Xiangbing ^a   Jin, Liang ^a   Cao, Rongyue ^a   Fan, Hao ^d   Li, Taiming ^a   Liu, Jingjing ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b RESEARCH INSTITUTE OF FORESTRY   (China)

^c XINXIANG MEDICAL UNIVERSITY   (China)

^d Shanghai Yijiu Biomedical Cooperation Ltd   (China)

Author keywords

Adjuvant epitope; DNA vaccine; Gastrin releasing peptide; Murine prostate carcinoma; Prime boost strategy

Indexed keywords

BCG VACCINE; DNA VACCINE; EPITOPE; GASTRIN RELEASING PEPTIDE; HSP65 GRP6 CHIMERIC PROTEIN; PLASMID VECTOR; RECOMBINANT PROTEIN; T HELPER EPITOPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CANCER GROWTH; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG EFFICACY; DRUG POTENCY; HUMORAL IMMUNITY; IMMUNOGENICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; TH0 CELL; TUMOR REJECTION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY AFFINITY; CANCER VACCINES; CARCINOMA; CELL LINE; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; GASTRIN-RELEASING PEPTIDE; HEAT-SHOCK PROTEINS; MALE; MICE; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; PEPTIDE FRAGMENTS; PROSTATIC NEOPLASMS; RECOMBINANT FUSION PROTEINS; VACCINES, DNA; VACCINES, SYNTHETIC;

EID: 68349123587     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.06.089     Document Type: Article

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