메뉴 건너뛰기




Volumn 7, Issue 3, 2007, Pages 229-241

Cancer vaccines for hormone/growth factor immune deprivation: A feasible approach for cancer treatment

Author keywords

Cancer vaccines; Endocrine therapy; Growth factors; Hormones; Immunotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; AVICINE; CANCER VACCINE; CHORIONIC GONADOTROPIN ANTIBODY; CISPLATIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOCETAXEL; FLUOROURACIL; GASTRIMMUNE; GASTRIN; GEFITINIB; GEMCITABINE; GONADIMMUNE; GONADORELIN; INSEGIA; LUTEINIZING HORMONE; NORELIN; PLACEBO; RECOMBINANT EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 34247860903     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800907780618310     Document Type: Article
Times cited : (33)

References (87)
  • 1
    • 34247877219 scopus 로고    scopus 로고
    • Cavalli, F.; Hansen, H. H.; Kaye, S. B. Textbook in Medical Oncology; Third edition. Taylor & Francis Ed., London and New York, 2004.
    • Cavalli, F.; Hansen, H. H.; Kaye, S. B. Textbook in Medical Oncology; Third edition. Taylor & Francis Ed., London and New York, 2004.
  • 3
    • 0028955388 scopus 로고
    • Epidermal growth factor derived peptides and their receptors in human malignancies
    • Salomon, D. S.; Brandt, R.; Ciardiello, E.; Normanno, N.: Epidermal growth factor derived peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. 1995, 19, 183-232.
    • (1995) Crit. Rev. Oncol. Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, E.3    Normanno, N.4
  • 4
    • 0027170357 scopus 로고
    • Evidence for the role of EGF receptor in the progression of human lung carcinoma
    • Pavelik, K.; Banjac, Z.; Pavelic, J.; Spaventi, S. Evidence for the role of EGF receptor in the progression of human lung carcinoma. Anticancer Res. 1993, 13, 1133-1137.
    • (1993) Anticancer Res , vol.13 , pp. 1133-1137
    • Pavelik, K.1    Banjac, Z.2    Pavelic, J.3    Spaventi, S.4
  • 5
    • 9044251203 scopus 로고    scopus 로고
    • The prognostic value of epidermal growth factor receptor mRNA expression in primary ovarian cancer
    • Bartlett, J. M.; Langdon, S. P.; Simpson, B. J.; Stewart, M.; Katsaros, D.; Sismondi, P. The prognostic value of epidermal growth factor receptor mRNA expression in primary ovarian cancer. Br. J. Cancer 1996, 73, 301-306.
    • (1996) Br. J. Cancer , vol.73 , pp. 301-306
    • Bartlett, J.M.1    Langdon, S.P.2    Simpson, B.J.3    Stewart, M.4    Katsaros, D.5    Sismondi, P.6
  • 6
    • 0027415146 scopus 로고
    • The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor and mdr gene expression in colorectal cancer
    • Mayer, A.; Takimoto, M.; Fritz, E.; Schellander, G.; Kofler, K.; Ludwing, H. The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor and mdr gene expression in colorectal cancer. Cancer 1993, 71, 2454-2460.
    • (1993) Cancer , vol.71 , pp. 2454-2460
    • Mayer, A.1    Takimoto, M.2    Fritz, E.3    Schellander, G.4    Kofler, K.5    Ludwing, H.6
  • 7
    • 0032478998 scopus 로고    scopus 로고
    • Levels of TGF alpha and EGFR protein in head and neck squamous cell lung carcinomas and patient survival
    • Grandis, J. R.; Melhem, M. H.; Gooding, W. E.; Day, R.; Holst, V. A.; Wagener, M. M. Levels of TGF alpha and EGFR protein in head and neck squamous cell lung carcinomas and patient survival. J. Natl. Cancer Inst. 1998, 90, 824-832.
    • (1998) J. Natl. Cancer Inst , vol.90 , pp. 824-832
    • Grandis, J.R.1    Melhem, M.H.2    Gooding, W.E.3    Day, R.4    Holst, V.A.5    Wagener, M.M.6
  • 8
    • 0023893053 scopus 로고
    • Receptors for epidermal growth factor and estrogen as predictors of relapse in patients with mammary carcinoma
    • Ríos, M. A.; Macías, A.; Pérez, R.; Lage, A. Skoog, L. Receptors for epidermal growth factor and estrogen as predictors of relapse in patients with mammary carcinoma. Anticancer Res. 1988, 8, 173-176.
    • (1988) Anticancer Res , vol.8 , pp. 173-176
    • Ríos, M.A.1    Macías, A.2    Pérez, R.3    Lage, A.4    Skoog, L.5
  • 9
    • 0022749543 scopus 로고
    • Receptors for epidermal growth factor in human carcinomas and their metastases
    • Macías, A.; Azavedo, E.; Pérez, R.; Rutquist, L. E.; Skoog, L. Receptors for epidermal growth factor in human carcinomas and their metastases. Anticancer Res. 1986, 6, 849-852.
    • (1986) Anticancer Res , vol.6 , pp. 849-852
    • Macías, A.1    Azavedo, E.2    Pérez, R.3    Rutquist, L.E.4    Skoog, L.5
  • 10
    • 0023230566 scopus 로고
    • Prognostic significance of the receptor for epidermal growth factor in human mammary carcinoma
    • Macías, A.; Azavedo, E.; Hagerstrom, T.; Klintenberg, C.; Pérez, R.; Skoog, L. Prognostic significance of the receptor for epidermal growth factor in human mammary carcinoma. Anticancer Res. 1987, 7, 459-464.
    • (1987) Anticancer Res , vol.7 , pp. 459-464
    • Macías, A.1    Azavedo, E.2    Hagerstrom, T.3    Klintenberg, C.4    Pérez, R.5    Skoog, L.6
  • 11
    • 0037106273 scopus 로고    scopus 로고
    • Targeting the Epidermal Growth Factor Receptor for Cancer Therapy
    • s
    • Mendelsohn, J. Targeting the Epidermal Growth Factor Receptor for Cancer Therapy. J. Clin. Oncol. 2002, 20(18), 1s-13s.
    • (2002) J. Clin. Oncol , vol.20 , Issue.18
    • Mendelsohn, J.1
  • 12
    • 0022501030 scopus 로고
    • Transforming growth factor-alpha: A more potent angiogenic mediator than epidermal growth factor
    • Scheiberg, A. B.; Winkler, M. E.; Derynck, G. Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor. Science 1986, 232, 1250-1253.
    • (1986) Science , vol.232 , pp. 1250-1253
    • Scheiberg, A.B.1    Winkler, M.E.2    Derynck, G.3
  • 13
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D.; Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86, 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 14
    • 0012535815 scopus 로고
    • Los factores de Crecimiento y sus relaciones con la transformación maligna
    • Rodríguez, R. P.; Lage, A. Los factores de Crecimiento y sus relaciones con la transformación maligna. Interf. Biotecnol. 1986, 3, 179-209.
    • (1986) Interf. Biotecnol , vol.3 , pp. 179-209
    • Rodríguez, R.P.1    Lage, A.2
  • 15
    • 0041386348 scopus 로고    scopus 로고
    • Targeting epidermal growth factor receptor signalling: Early results and future trends in oncology
    • Lage, A.; Crombet, T.; González, G. Targeting epidermal growth factor receptor signalling: early results and future trends in oncology. Ann. Med. 2003, 35, 327-336.
    • (2003) Ann. Med , vol.35 , pp. 327-336
    • Lage, A.1    Crombet, T.2    González, G.3
  • 16
    • 16244394542 scopus 로고    scopus 로고
    • Gefitinib does not increase survival in lung cancer patients
    • Golsteyn, R. M. Gefitinib does not increase survival in lung cancer patients. Drug Discov. Today 2005, 6, 381.
    • (2005) Drug Discov. Today , vol.6 , pp. 381
    • Golsteyn, R.M.1
  • 17
    • 15944380406 scopus 로고    scopus 로고
    • Twombly, R. FDA Oncology Committee debates Iressa's status following negative trial results. J. Nat. Cancer Inst. 2005, 97, 473.
    • Twombly, R. FDA Oncology Committee debates Iressa's status following negative trial results. J. Nat. Cancer Inst. 2005, 97, 473.
  • 18
    • 0030004598 scopus 로고    scopus 로고
    • Peptide-based, but nor whole protein, vaccines elicit immunity to HER-2/neu, an oncogenic self protein
    • Disis, M. L.; Gralow, J. R.; Bernhard, H.; Hand, S. L.; Rubin, W. D.; Cheever, M. A. Peptide-based, but nor whole protein, vaccines elicit immunity to HER-2/neu, an oncogenic self protein. J. Immunol. 1996, 156, 3151-3158.
    • (1996) J. Immunol , vol.156 , pp. 3151-3158
    • Disis, M.L.1    Gralow, J.R.2    Bernhard, H.3    Hand, S.L.4    Rubin, W.D.5    Cheever, M.A.6
  • 19
    • 0036605567 scopus 로고    scopus 로고
    • Generation of T-cell immunity to the Her-2/neu protein after active immunization with Her-2/neu peptide-based vaccines
    • Disis, M. L.; Gooley, T. A. ; Rinn, K. ; Davis, D. ; Piepkorn, M. ; Cheever, M. A. ; Knutson, K. L.; Schiffman, K. Generation of T-cell immunity to the Her-2/neu protein after active immunization with Her-2/neu peptide-based vaccines. J. Clin. Oncol. 2002, 20, 2642-2632.
    • (2002) J. Clin. Oncol , vol.20 , pp. 2642-2632
    • Disis, M.L.1    Gooley, T.A.2    Rinn, K.3    Davis, D.4    Piepkorn, M.5    Cheever, M.A.6    Knutson, K.L.7    Schiffman, K.8
  • 20
    • 0030497413 scopus 로고    scopus 로고
    • Induction of Immune Recognition of Self Epidermal Growth Factor (EGF): Effect on EGF Biodistribution and Tumor Growth
    • González, G.; Sánchez, B.; Suarez, E.; Beausoleil, I.; Perez, O.; Lastre, M.; Lage, A.. Induction of Immune Recognition of Self Epidermal Growth Factor (EGF): Effect on EGF Biodistribution and Tumor Growth. Vaccine Res. 1996, 5, 233-244.
    • (1996) Vaccine Res , vol.5 , pp. 233-244
    • González, G.1    Sánchez, B.2    Suarez, E.3    Beausoleil, I.4    Perez, O.5    Lastre, M.6    Lage, A.7
  • 22
    • 0031775979 scopus 로고    scopus 로고
    • A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial
    • González, G.; Crombet, T.; Catalá, M.; Mirabal, V.; Hernandez, J. C.; González; Y.; Marinello, P.; Guillén, G.; Lage, A. A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial. Ann. Oncol. 1998, 9, 431-435.
    • (1998) Ann. Oncol , vol.9 , pp. 431-435
    • González, G.1    Crombet, T.2    Catalá, M.3    Mirabal, V.4    Hernandez, J.C.5    González, Y.6    Marinello, P.7    Guillén, G.8    Lage, A.9
  • 25
    • 33644589205 scopus 로고    scopus 로고
    • The enlargement of the hormone deprivation concept to the blocking of TGFα-autocrine loop: EGFR signalling inhibition
    • Mulet, A.; Garrido, G.; Alvarez, A.; Menéndez, T.; Bohmer, F. D.; Pérez, R.; Fernández, L. E. The enlargement of the hormone deprivation concept to the blocking of TGFα-autocrine loop: EGFR signalling inhibition. Cancer Immunol. Immunother. 2006, 55, 628-638.
    • (2006) Cancer Immunol. Immunother , vol.55 , pp. 628-638
    • Mulet, A.1    Garrido, G.2    Alvarez, A.3    Menéndez, T.4    Bohmer, F.D.5    Pérez, R.6    Fernández, L.E.7
  • 26
    • 0019507155 scopus 로고
    • Natural antibodies against tubulin, actin, myoglobin, thyroglobulin, fetuin, albumin and transferrin are present in normal human sera, and monoclonal immunoglobulins from multiple myeloma and Waldenstrom's macroglobulinemia may express similar antibody specificities
    • Avrameas, S.; Guilbert, B.; Dighiero, G. Natural antibodies against tubulin, actin, myoglobin, thyroglobulin, fetuin, albumin and transferrin are present in normal human sera, and monoclonal immunoglobulins from multiple myeloma and Waldenstrom's macroglobulinemia may express similar antibody specificities. Ann. Immunol. 1981, 132C, 231-236.
    • (1981) Ann. Immunol , vol.132 C , pp. 231-236
    • Avrameas, S.1    Guilbert, B.2    Dighiero, G.3
  • 27
    • 0022931255 scopus 로고
    • Regulation of autoimmune disease: Physiological and therapeutic
    • Cohen, I. R. Regulation of autoimmune disease: physiological and therapeutic. Immunol. Rev. 1986, 94, 5-21.
    • (1986) Immunol. Rev , vol.94 , pp. 5-21
    • Cohen, I.R.1
  • 28
    • 0025021670 scopus 로고    scopus 로고
    • Nikolic-Zugic, J.; Bevan, M. J. Role of self-peptides in positively selecting the T cell repertoire. Nature 1990, 344, 65-67.
    • Nikolic-Zugic, J.; Bevan, M. J. Role of self-peptides in positively selecting the T cell repertoire. Nature 1990, 344, 65-67.
  • 30
    • 0028133043 scopus 로고
    • Global analysis of antibody repertoires. 1. An immunoblot method for the quantitative screening of a large number of reactivities
    • Haury, M.; Grandien, A.; Sundblad, A.; Coutinho, A.; Nobrega, A. Global analysis of antibody repertoires. 1. An immunoblot method for the quantitative screening of a large number of reactivities. Scand. J. Immunol. 1994, 39, 79-87.
    • (1994) Scand. J. Immunol , vol.39 , pp. 79-87
    • Haury, M.1    Grandien, A.2    Sundblad, A.3    Coutinho, A.4    Nobrega, A.5
  • 31
    • 1542327606 scopus 로고    scopus 로고
    • Identification of tumor antigens by serological analysis of cDNA expression cloning
    • Li, G.; Miles, A.; Line, A.; Rees, R. C. Identification of tumor antigens by serological analysis of cDNA expression cloning. Cancer Immunol. Immunother. 2004, 53, 139-143.
    • (2004) Cancer Immunol. Immunother , vol.53 , pp. 139-143
    • Li, G.1    Miles, A.2    Line, A.3    Rees, R.C.4
  • 32
    • 0033106415 scopus 로고    scopus 로고
    • T cell proliferative response on type 1 diabetes patients and healthy individuals to human hsp60 and its peptides
    • Abulafia-Lapid, R.; Elias, D.; Raz, I.; Keren-Zur, Y.; Atlan, H.; Cohen, I. R. T cell proliferative response on type 1 diabetes patients and healthy individuals to human hsp60 and its peptides. J. Autoimun. 1999, 12, 121-129.
    • (1999) J. Autoimun , vol.12 , pp. 121-129
    • Abulafia-Lapid, R.1    Elias, D.2    Raz, I.3    Keren-Zur, Y.4    Atlan, H.5    Cohen, I.R.6
  • 33
    • 0020551984 scopus 로고
    • Isolation of myelin basic protein reactive T-cell lines from normal human blood
    • Burns, J.; Rosenzweig, A.; Xweiman, B.; Lisak, R. P. Isolation of myelin basic protein reactive T-cell lines from normal human blood. Cell Immunol. 1983, 81, 435-440.
    • (1983) Cell Immunol , vol.81 , pp. 435-440
    • Burns, J.1    Rosenzweig, A.2    Xweiman, B.3    Lisak, R.P.4
  • 34
    • 0028229395 scopus 로고
    • Insulin as a target antigen in autoimmune diabetes: A natural repertoire as the source of antibody response
    • Petersen, K. G.; Khalaf, A. N.; Naithani, V.; Fabry, M.; Gattner, H. Insulin as a target antigen in autoimmune diabetes: a natural repertoire as the source of antibody response. Acta Diabetol. 1994, 31, 66-72.
    • (1994) Acta Diabetol , vol.31 , pp. 66-72
    • Petersen, K.G.1    Khalaf, A.N.2    Naithani, V.3    Fabry, M.4    Gattner, H.5
  • 35
    • 0021797742 scopus 로고
    • Various expressions of a unique anti-human hyroglobulin antibody repertoire in normal state and autoimmune disease
    • Ruf, J.; Carayon, P.; Lissitzky, S. Various expressions of a unique anti-human hyroglobulin antibody repertoire in normal state and autoimmune disease. Eur. J. Immunol. 1985, 15, 268-272.
    • (1985) Eur. J. Immunol , vol.15 , pp. 268-272
    • Ruf, J.1    Carayon, P.2    Lissitzky, S.3
  • 36
    • 0035508638 scopus 로고    scopus 로고
    • Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice
    • Quintana, F. J.; Cohen, I. R. Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice. J. Autoimmun. 2001, 17, 191-197.
    • (2001) J. Autoimmun , vol.17 , pp. 191-197
    • Quintana, F.J.1    Cohen, I.R.2
  • 37
    • 0025836121 scopus 로고
    • Recognition of self antigens by skin-derived T cells with invariant gamma delta antigen receptors
    • Havran, W. L.; Chien, Y. H.; Allison, J. P. Recognition of self antigens by skin-derived T cells with invariant gamma delta antigen receptors. Science 1991, 252, 1430-1432.
    • (1991) Science , vol.252 , pp. 1430-1432
    • Havran, W.L.1    Chien, Y.H.2    Allison, J.P.3
  • 38
    • 0026033502 scopus 로고
    • Autoimmunity, microbial immunity and the immunological homunculus
    • Cohen, I. R.; Toung, D. B. Autoimmunity, microbial immunity and the immunological homunculus. Immunol. Today 1991, 12, 105-110.
    • (1991) Immunol. Today , vol.12 , pp. 105-110
    • Cohen, I.R.1    Toung, D.B.2
  • 39
    • 0026439389 scopus 로고
    • The cognitive paradigm and the immunological homunculus
    • Cohen, I. R. The cognitive paradigm and the immunological homunculus. Immunol. Today 1992, 13, 490-494.
    • (1992) Immunol. Today , vol.13 , pp. 490-494
    • Cohen, I.R.1
  • 40
    • 0004105979 scopus 로고    scopus 로고
    • First edition. Elsevier Sciences & Technology Books
    • Yehuda Shoenfeld. The Decade of Autoimmunity; First edition. Elsevier Sciences & Technology Books, 1999.
    • (1999) The Decade of Autoimmunity
    • Shoenfeld, Y.1
  • 41
    • 0002862892 scopus 로고    scopus 로고
    • Autoimmunization to Epidermal Growth Factor, a component of the immunological homunculus
    • González, G.; Montero, E.; Leon, K.; Cohen, L. R.; Lage. A. Autoimmunization to Epidermal Growth Factor, a component of the immunological homunculus. Autoimmun. Rev. 2002, 1, 89-95.
    • (2002) Autoimmun. Rev , vol.1 , pp. 89-95
    • González, G.1    Montero, E.2    Leon, K.3    Cohen, L.R.4    Lage, A.5
  • 42
    • 0014887939 scopus 로고
    • The concept of immunological surveillance
    • Burnet, F. M. The concept of immunological surveillance. Prog. Exp. Tumor Res. 1970, 13, 1-27.
    • (1970) Prog. Exp. Tumor Res , vol.13 , pp. 1-27
    • Burnet, F.M.1
  • 43
    • 0020262511 scopus 로고
    • On immunosurveillance in human cancer
    • Thomas, L. On immunosurveillance in human cancer. Yale J. Biol. Med. 1982, 55, 329-333.
    • (1982) Yale J. Biol. Med , vol.55 , pp. 329-333
    • Thomas, L.1
  • 46
    • 0035394233 scopus 로고    scopus 로고
    • Proliferative activity of intratumoral CD8+ T-lymphocutes as a prognostic factor in human renal carcinoma: Clinicopathologic demonstration of antitumor immunity
    • Nakano, O.; Sato, M.; Naito, Y.; Suzuki, K.; Orikasa, S.; Aizawa, M.; Suzuki, Y.; Shintaku, I.; Nagura, H.; Ohtani, H. Proliferative activity of intratumoral CD8+ T-lymphocutes as a prognostic factor in human renal carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res. 2001, 61, 5132-5136.
    • (2001) Cancer Res , vol.61 , pp. 5132-5136
    • Nakano, O.1    Sato, M.2    Naito, Y.3    Suzuki, K.4    Orikasa, S.5    Aizawa, M.6    Suzuki, Y.7    Shintaku, I.8    Nagura, H.9    Ohtani, H.10
  • 47
    • 0032529466 scopus 로고    scopus 로고
    • Naito, Y.; Saito, K.; Shiiba, K.; Ohuchi, A.: Saigenji, K.; Nagura, H.; Ohtani, H. CD8+ T cells infiltrated within cancer cells nests as a prognostic factor in human colorectal cancer. Cancer Res. 1998, 58, 3491-3494.
    • Naito, Y.; Saito, K.; Shiiba, K.; Ohuchi, A.: Saigenji, K.; Nagura, H.; Ohtani, H. CD8+ T cells infiltrated within cancer cells nests as a prognostic factor in human colorectal cancer. Cancer Res. 1998, 58, 3491-3494.
  • 48
    • 0030659077 scopus 로고    scopus 로고
    • Study of tumor infiltrating lymphocytes nad transforming growth factor-beta as prognostic factors in breast carcinoma
    • Marrogi, A. J.; Munshi, A.; Merogi, A. J.; Ohadike, Y.; El-Habashi, A.; Marrogi, O. L.; Freeman, S. M. Study of tumor infiltrating lymphocytes nad transforming growth factor-beta as prognostic factors in breast carcinoma. Int. J. Cancer 1997, 74, 492-501.
    • (1997) Int. J. Cancer , vol.74 , pp. 492-501
    • Marrogi, A.J.1    Munshi, A.2    Merogi, A.J.3    Ohadike, Y.4    El-Habashi, A.5    Marrogi, O.L.6    Freeman, S.M.7
  • 49
    • 0035872423 scopus 로고    scopus 로고
    • Prognostic significance of activated CD8+ T cell infiltrations within esophageal carcinomas
    • Schumacher, K.; Haensch, W.; Roefzaad, C.; Schlag, P. M. Prognostic significance of activated CD8+ T cell infiltrations within esophageal carcinomas. Cancer Res. 2001, 61, 3932-3936.
    • (2001) Cancer Res , vol.61 , pp. 3932-3936
    • Schumacher, K.1    Haensch, W.2    Roefzaad, C.3    Schlag, P.M.4
  • 52
    • 1842562212 scopus 로고    scopus 로고
    • Tolerance and cancer: Mechanisms of tumor evasion and strategies for breaking tolerance
    • Mapara, M. Y.; Sykes, M. Tolerance and cancer: Mechanisms of tumor evasion and strategies for breaking tolerance. J. Clin. Oncol. 2004, 22, 1136-1151.
    • (2004) J. Clin. Oncol , vol.22 , pp. 1136-1151
    • Mapara, M.Y.1    Sykes, M.2
  • 53
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumor immunobiology and Immunotherapy
    • Rosenberg, S. A. Progress in human tumor immunobiology and Immunotherapy. Nature 2001, 411, 380-384.
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.A.1
  • 54
    • 0036322870 scopus 로고    scopus 로고
    • Cancer vaccines: Progress reveals new complexities
    • Yu, Z.; Restifo, N. P. Cancer vaccines: progress reveals new complexities. J. Clin. Invest. 2002, 110, 289-294.
    • (2002) J. Clin. Invest , vol.110 , pp. 289-294
    • Yu, Z.1    Restifo, N.P.2
  • 55
    • 11844265528 scopus 로고    scopus 로고
    • Mocellin, S.; Mandruzano, S.; Bronte, V.; Lise, M.; Nitti, D. Part I: Vaccines for solid tumors. Lancet Oncol. 2004, 5, 681-689.
    • Mocellin, S.; Mandruzano, S.; Bronte, V.; Lise, M.; Nitti, D. Part I: Vaccines for solid tumors. Lancet Oncol. 2004, 5, 681-689.
  • 57
    • 29044433581 scopus 로고    scopus 로고
    • Therapeutic Cancer Vaccines: At Midway Between Immunology and Pharmacology
    • Lage, A.; Pérez, R.; Fernandez, L. E.: Therapeutic Cancer Vaccines: At Midway Between Immunology and Pharmacology. Curr. Cancer Drugs Targets 2005, 5, 611-627.
    • (2005) Curr. Cancer Drugs Targets , vol.5 , pp. 611-627
    • Lage, A.1    Pérez, R.2    Fernandez, L.E.3
  • 58
    • 0017078393 scopus 로고
    • Isoimmunization against human chorionic gonadotropin with conjugates of processed β-subunit of the hormone and tetanus toxoid
    • Talwar, G. P.; Sharma, N. C.; Dubey, S. K.; Salahuddin, M.; Das, C.; Ramakrishnan, S.; Kumar, S. Isoimmunization against human chorionic gonadotropin with conjugates of processed β-subunit of the hormone and tetanus toxoid. Proc. Nat. Acad. Sci. USA 1976, 73, 218-222.
    • (1976) Proc. Nat. Acad. Sci. USA , vol.73 , pp. 218-222
    • Talwar, G.P.1    Sharma, N.C.2    Dubey, S.K.3    Salahuddin, M.4    Das, C.5    Ramakrishnan, S.6    Kumar, S.7
  • 60
    • 0030890510 scopus 로고    scopus 로고
    • Vaccines for control fertility and hormone-dependent cancers
    • Talwar, G. P. Vaccines for control fertility and hormone-dependent cancers. Immunol. Cell Biol. 1997, 75, 184-189.
    • (1997) Immunol. Cell Biol , vol.75 , pp. 184-189
    • Talwar, G.P.1
  • 61
    • 0032614547 scopus 로고    scopus 로고
    • Human chorionic gonadotropin as a target for cancer vaccines
    • Triozzi, P. L.; Stevens, V. C. Human chorionic gonadotropin as a target for cancer vaccines. Oncol. Rep. 1999, 6, 7-17.
    • (1999) Oncol. Rep , vol.6 , pp. 7-17
    • Triozzi, P.L.1    Stevens, V.C.2
  • 62
    • 0035992254 scopus 로고    scopus 로고
    • Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: Antibody response is associated with improved survival
    • Moulton, H. M.; Yoshihara, P. H.; Mason, D. H.; Iversen, P. L.; Triozzi, P. L. Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival. Clin. Cancer Res. 2002, 8, 2044-2051.
    • (2002) Clin. Cancer Res , vol.8 , pp. 2044-2051
    • Moulton, H.M.1    Yoshihara, P.H.2    Mason, D.H.3    Iversen, P.L.4    Triozzi, P.L.5
  • 64
    • 0024506965 scopus 로고
    • Gastrin : Growth enhancing effects on human gastric and colonic tumor cells
    • Watson, S.; Durrant, L.; Morris, D. Gastrin : growth enhancing effects on human gastric and colonic tumor cells. Br. J. Cancer 1989, 59, 554-558.
    • (1989) Br. J. Cancer , vol.59 , pp. 554-558
    • Watson, S.1    Durrant, L.2    Morris, D.3
  • 65
    • 0022646778 scopus 로고
    • Effects of gastrin, glutamine and somatosin on the in vitro growth of normal and malignant human gastric mucosa cells
    • Moyer, M. P.; Armstrong, A.; Aust, J. B. Effects of gastrin, glutamine and somatosin on the in vitro growth of normal and malignant human gastric mucosa cells. Arch. Surg. 1986, 121, 285-288.
    • (1986) Arch. Surg , vol.121 , pp. 285-288
    • Moyer, M.P.1    Armstrong, A.2    Aust, J.B.3
  • 66
    • 0030020865 scopus 로고    scopus 로고
    • Gastrimune raises antibodies that neutralize amidated and glycine-extended gastrin-17 and inhibit the tumor growth of colon cancer
    • Watson, S. A.; Michaeli, D.; Grimes, S.; Morris, T. M.; Robinson, G.; Varro, A.; Justin, T. A.; Hardcastle, J. D. Gastrimune raises antibodies that neutralize amidated and glycine-extended gastrin-17 and inhibit the tumor growth of colon cancer. Cancer Res. 1996, 15, 880-885.
    • (1996) Cancer Res , vol.15 , pp. 880-885
    • Watson, S.A.1    Michaeli, D.2    Grimes, S.3    Morris, T.M.4    Robinson, G.5    Varro, A.6    Justin, T.A.7    Hardcastle, J.D.8
  • 67
    • 0034485821 scopus 로고    scopus 로고
    • Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer
    • Smith, A. M.; Justin, T.; Michaeli, D.; Watson, A. Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer. Clin. Cancer Res. 2000, 6, 4719-4724.
    • (2000) Clin. Cancer Res , vol.6 , pp. 4719-4724
    • Smith, A.M.1    Justin, T.2    Michaeli, D.3    Watson, A.4
  • 69
    • 2542627357 scopus 로고    scopus 로고
    • Gillian, A. D.; Watson, S. A.; Henwood, M.; McKenzie, A. J.; Humphreys, J. E.; Elder, J.; Iftikhar, S. Y.; Welch, N.; Fielding, J.; Broome, P.; Michaeli, D. A phase II study of G17DT in gastric carcinoma. Eur. J. Surg. Oncol. 2004, 30, 536-543.
    • Gillian, A. D.; Watson, S. A.; Henwood, M.; McKenzie, A. J.; Humphreys, J. E.; Elder, J.; Iftikhar, S. Y.; Welch, N.; Fielding, J.; Broome, P.; Michaeli, D. A phase II study of G17DT in gastric carcinoma. Eur. J. Surg. Oncol. 2004, 30, 536-543.
  • 70
    • 18744374426 scopus 로고    scopus 로고
    • Randomized, double blind, placebo-controlled, multicenter, group-sequential trial of G17DT in patients with advanced pancreatic cancer
    • Gillian, A. D. Randomized, double blind, placebo-controlled, multicenter, group-sequential trial of G17DT in patients with advanced pancreatic cancer. J. Clin. Oncol. 2004, 22(Suppl.), 2511.
    • (2004) J. Clin. Oncol , vol.22 , Issue.SUPPL. , pp. 2511
    • Gillian, A.D.1
  • 71
    • 34247878893 scopus 로고    scopus 로고
    • Immune response to Gastrin-17 as an independent covariate for survival in colorectal, gastric and pancreatic cancers
    • Broome, P.; Bruck, R.; Michaeli, D. Immune response to Gastrin-17 as an independent covariate for survival in colorectal, gastric and pancreatic cancers. J. Clin. Oncol. 2004, 22(Suppl.), 4073.
    • (2004) J. Clin. Oncol , vol.22 , Issue.SUPPL. , pp. 4073
    • Broome, P.1    Bruck, R.2    Michaeli, D.3
  • 72
    • 28344451391 scopus 로고    scopus 로고
    • G17DT + gemcitabine [Gem]versus placebo + Gem in untreated subjects with locally advanced, recurrent or metastatic adenocarcinoma of the pancreas: Results of a rendomized, double-blind, multinational, multicenter study
    • Shapiro, J.; Marshall, H.; Karasek, P.; Figer, A.; Oettle, H.; Couture, G.; Jeziorski, K.; Broome, P.; Hawskins R. G17DT + gemcitabine [Gem]versus placebo + Gem in untreated subjects with locally advanced, recurrent or metastatic adenocarcinoma of the pancreas: Results of a rendomized, double-blind, multinational, multicenter study. J. Clin. Oncol. 2005, 23(Suppl.), 1098.
    • (2005) J. Clin. Oncol , vol.23 , Issue.SUPPL. , pp. 1098
    • Shapiro, J.1    Marshall, H.2    Karasek, P.3    Figer, A.4    Oettle, H.5    Couture, G.6    Jeziorski, K.7    Broome, P.8    Hawskins, R.9
  • 73
    • 33646358252 scopus 로고    scopus 로고
    • An Open-Label Multinational, Multicenter Study of G17DT Vaccination Combined with Cisplatin and 5-Fluorouracil in Patients with Untreated, Advanced Gastric or Gastroesophageal Cancer: The GC4 Study
    • Ajani, J. A.; Hecht, J. R.; Ho, L.; Baker, J.; Oorgiesen, M.; Eduljee, A.; Michaeli, D. An Open-Label Multinational, Multicenter Study of G17DT Vaccination Combined with Cisplatin and 5-Fluorouracil in Patients with Untreated, Advanced Gastric or Gastroesophageal Cancer: The GC4 Study. Cancer 2006, 106, 1908-1916.
    • (2006) Cancer , vol.106 , pp. 1908-1916
    • Ajani, J.A.1    Hecht, J.R.2    Ho, L.3    Baker, J.4    Oorgiesen, M.5    Eduljee, A.6    Michaeli, D.7
  • 74
    • 0001189211 scopus 로고
    • Studies in prostatic cancer II: The effect of castration on advanced cancer of the prostate gland
    • Huggins, C.; Hodges, C. V. Studies in prostatic cancer II: The effect of castration on advanced cancer of the prostate gland. Arch. Surg. 1941, 43, 209-223.
    • (1941) Arch. Surg , vol.43 , pp. 209-223
    • Huggins, C.1    Hodges, C.V.2
  • 75
    • 0031438761 scopus 로고    scopus 로고
    • Growth inhibitory actions of analogues of luteinizing hormone releasing hormone on tumor cells
    • Emons, G.; Ortmann, O.; Schulz, K. D.; Schally, A. V. Growth inhibitory actions of analogues of luteinizing hormone releasing hormone on tumor cells. Trends Endocrinol. Metab. 1997, 8, 355-361.
    • (1997) Trends Endocrinol. Metab , vol.8 , pp. 355-361
    • Emons, G.1    Ortmann, O.2    Schulz, K.D.3    Schally, A.V.4
  • 76
    • 0012612792 scopus 로고    scopus 로고
    • Advanced prostate cancer. A state-of-the-art guide to pharmacological management
    • Naghton, M.; Picus, J. Advanced prostate cancer. A state-of-the-art guide to pharmacological management. Am. J. Cancer 2002, 1, 13-22.
    • (2002) Am. J. Cancer , vol.1 , pp. 13-22
    • Naghton, M.1    Picus, J.2
  • 77
    • 0036669114 scopus 로고    scopus 로고
    • Controversies in the systhemic anagement of patients with evidence of biochemical failure following radical prostactectomy
    • Dreicer, R. Controversies in the systhemic anagement of patients with evidence of biochemical failure following radical prostactectomy. Cancer Treat. Rev. 2002, 28, 189-194.
    • (2002) Cancer Treat. Rev , vol.28 , pp. 189-194
    • Dreicer, R.1
  • 78
    • 0030976445 scopus 로고    scopus 로고
    • Effect of active immunization against luteinizing hormonereleasing hormone on the androgen-sensitive Dunning R3327-PAP and androgen-independent Dunning R3327-AT2.1 prostate cell lines
    • Fuerst, J.; Fiebiger, E.; Jungwirth, A.; Mack, D.; Talwar, G. P.; Frick, J.; Rovan, E. Effect of active immunization against luteinizing hormonereleasing hormone on the androgen-sensitive Dunning R3327-PAP and androgen-independent Dunning R3327-AT2.1 prostate cell lines. Prostate 1997, 32, 77-84.
    • (1997) Prostate , vol.32 , pp. 77-84
    • Fuerst, J.1    Fiebiger, E.2    Jungwirth, A.3    Mack, D.4    Talwar, G.P.5    Frick, J.6    Rovan, E.7
  • 79
    • 0030890510 scopus 로고    scopus 로고
    • Vaccine for control of fertility and hormone-dependent cancers
    • Talwar, G. P. Vaccine for control of fertility and hormone-dependent cancers. Immunol. Cell Biol. 1997, 75, 184-189
    • (1997) Immunol. Cell Biol , vol.75 , pp. 184-189
    • Talwar, G.P.1
  • 80
    • 0033930953 scopus 로고    scopus 로고
    • Anti-GnRH antibodies can induce castrate levels of testosterone in patients with advanced prostate cancer
    • Simms, M. S.; Scholfield, D. P.; Jacobs, E.; Michaeli, D.; Broome, P.; Humphreys, J. E.; Bishop, M. C. Anti-GnRH antibodies can induce castrate levels of testosterone in patients with advanced prostate cancer. Br. J. Cancer 2000, 83, 443-446.
    • (2000) Br. J. Cancer , vol.83 , pp. 443-446
    • Simms, M.S.1    Scholfield, D.P.2    Jacobs, E.3    Michaeli, D.4    Broome, P.5    Humphreys, J.E.6    Bishop, M.C.7
  • 82
    • 3543132219 scopus 로고    scopus 로고
    • A recombinant luteinizing-hormone-releasing-hormone immunogen bioeffective in causing prostatic atrophy
    • Talwar, G. P.; Raina, K.; Grupta, J. C.; Ray, R.; Wadhwa, S.; Ali, M. M. A recombinant luteinizing-hormone-releasing-hormone immunogen bioeffective in causing prostatic atrophy. Vaccine 2004, 22, 3713-3721.
    • (2004) Vaccine , vol.22 , pp. 3713-3721
    • Talwar, G.P.1    Raina, K.2    Grupta, J.C.3    Ray, R.4    Wadhwa, S.5    Ali, M.M.6
  • 83
    • 0742289493 scopus 로고    scopus 로고
    • A vaccination strategy for a long term suppression of androgens in advanced prostate cancer
    • Parkinson, R. J.; Simms, M.; Broome, P.; Humphreys, J. E.; Bishop, M. C. A vaccination strategy for a long term suppression of androgens in advanced prostate cancer. Eur. Urol. 2004, 45, 171-174.
    • (2004) Eur. Urol , vol.45 , pp. 171-174
    • Parkinson, R.J.1    Simms, M.2    Broome, P.3    Humphreys, J.E.4    Bishop, M.C.5
  • 84
    • 28744454796 scopus 로고    scopus 로고
    • Effect of doxetacel chemotherapy on the activity of a gonadotropin releasing hormone vaccine in patients with advanced prostate cancer
    • Triozzi, P. L.; Bolger, G. B.; Neidhart, J.; Rinchart, J. J.; Saleh, M.; Allen, K. O.; Sellers, S.; Waddel, M. J. Effect of doxetacel chemotherapy on the activity of a gonadotropin releasing hormone vaccine in patients with advanced prostate cancer. Prostate 2005, 65, 316-321.
    • (2005) Prostate , vol.65 , pp. 316-321
    • Triozzi, P.L.1    Bolger, G.B.2    Neidhart, J.3    Rinchart, J.J.4    Saleh, M.5    Allen, K.O.6    Sellers, S.7    Waddel, M.J.8
  • 85
    • 34247896691 scopus 로고    scopus 로고
    • www.ymbiosciences.com
  • 86
    • 0035202615 scopus 로고    scopus 로고
    • Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
    • Goronzy, J. J.; Fulbright, J. W.; Crowson, C. S.; Poland, G. A.; O'Fallon, W. M.; Weyand, C. M. Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. Virology 2001, 75, 12182-12187.
    • (2001) Virology , vol.75 , pp. 12182-12187
    • Goronzy, J.J.1    Fulbright, J.W.2    Crowson, C.S.3    Poland, G.A.4    O'Fallon, W.M.5    Weyand, C.M.6
  • 87
    • 1142275269 scopus 로고    scopus 로고
    • Age-related changes in lymphocyte development and function
    • Linton, P. J.; Dorshkind, K. Age-related changes in lymphocyte development and function. Nat. Immunol. 2004, 5, 133-135.
    • (2004) Nat. Immunol , vol.5 , pp. 133-135
    • Linton, P.J.1    Dorshkind, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.