Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice

PLoS Genetics

Volumn 5, Issue 7, 2009, Pages

  Divangahi, Maziar ^a   Balghi, Haouaria ^a   Danialou, Gawiyou ^a   Comtois, Alain S ^a   Demoule, Alexandre ^a,b   Ernest, Sheila ^a   Haston, Christina ^a   Robert, Renaud ^c   Hanrahan, John W ^c   Radzioch, Danuta ^d   Petrof, Basil J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b SORBONNE UNIVERSITÉ   (France)

^c MCGILL UNIVERSITY   (Canada)

^d RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATROGIN 1; CALCIUM; CHEMOKINE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUSCLE RING FINGER 1 PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; UBIQUITIN PROTEIN LIGASE E3;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYSTIC FIBROSIS; DEPOLARIZATION; DIAPHRAGM MOVEMENT; DIAPHRAGM MUSCLE; DISEASE PREDISPOSITION; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LUNG INFECTION; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE FUNCTION; MYOTUBE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PSEUDOMONAS AERUGINOSA; RECEPTOR UPREGULATION; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; DIAPHRAGM; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; MUSCLE WEAKNESS; PATHOLOGY; PATHOPHYSIOLOGY;

MURINAE; MUS; PSEUDOMONAS AERUGINOSA;

ANIMALS; CALCIUM; CELLS, CULTURED; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKINES; DIAPHRAGM; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE WEAKNESS; MUSCLE, SKELETAL;

EID: 68249094323     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000586     Document Type: Article

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