Structural Reorganization of α-Synuclein at Low pH Observed by NMR and REMD Simulations

Journal of Molecular Biology

Volumn 391, Issue 4, 2009, Pages 784-796

  Wu, Kuen Phon ^a   Weinstock, Daniel S ^b   Narayanan, Chitra ^a   Levy, Ronald M ^a,b   Baum, Jean ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

NMR; Parkinson's disease; replica exchange molecular dynamics; synuclein

Indexed keywords

ALPHA SYNUCLEIN; AMINO ACID; AMYLOID BETA PROTEIN;

ACIDITY; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HYDRODYNAMICS; HYDROPHILICITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SIMULATION; STRUCTURE ANALYSIS;

EID: 68149132468     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.06.063     Document Type: Article

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