Benzene activates caspase-4 and -12 at the transcription level, without an association with apoptosis, in mouse bone marrow cells lacking the p53 gene

Archives of Toxicology

Volumn 83, Issue 8, 2009, Pages 795-803

  Yi, Jung Yeon ^a   Hirabayashi, Yoko ^b   Choi, Yang Kyu ^c   Kodama, Yukio ^b   Kanno, Jun ^b   Han, Jeong Hee ^a   Inoue, Tohru ^b   Yoon, Byung Il ^a  

^a Kangwon National University   (South Korea)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c Konkuk University   (South Korea)

Author keywords

Apoptosis; Benzene; Bone marrow; Caspase 12; Caspase 4; Mouse, p53

Indexed keywords

BENZENE; CASPASE 12; CASPASE 4; LIPOCORTIN 5; MESSENGER RNA; PROTEIN P53; APOPTOSIS REGULATORY PROTEIN; CASP11 PROTEIN, MOUSE; CASP12 PROTEIN, MOUSE; CASPASE;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; APLASTIC ANEMIA; APOPTOSIS; ARTICLE; BLOOD CELL; BLOOD TOXICITY; BONE MARROW CELL; BONE MARROW TOXICITY; CELL CYCLE ARREST; CONTROLLED STUDY; COULTER COUNTER; DNA DETERMINATION; ENDOPLASMIC RETICULUM; GENOTYPE; INFLAMMATION; LEUKOCYTE COUNT; LYMPHOMA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CBA MOUSE; CYTOLOGY; DNA FRAGMENTATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LEUKOCYTE; METABOLISM; MOUSE MUTANT;

ALIAS; MUS; ZEA MAYS;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BENZENE; BONE MARROW CELLS; CASPASE 12; CASPASES; DNA FRAGMENTATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, P53; LEUKOCYTES; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT;

EID: 68149131527     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-009-0420-4     Document Type: Article

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