메뉴 건너뛰기




Volumn 5, Issue 1, 2008, Pages

Academic HTS: diverse portraits

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMATION; COMBINATORIAL LIBRARY; COMPUTER MODEL; COMPUTER PROGRAM; DRUG INDUSTRY; DRUG RESEARCH; HIGH THROUGHPUT SCREENING; MASS SPECTROMETRY; MICROTITER PLATE ASSAY; REPRODUCIBILITY; REVIEW; RNA INTERFERENCE; UNIVERSITY;

EID: 68049144962     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2009.01.001     Document Type: Review
Times cited : (3)

References (30)
  • 1
    • 62549088346 scopus 로고    scopus 로고
    • The truth about drug innovation: thirty-five summary case histories on private sector contributions to pharmaceutical science
    • Zycher B., et al. The truth about drug innovation: thirty-five summary case histories on private sector contributions to pharmaceutical science. Med. Prog. Rep. 6 (2008) 1-37
    • (2008) Med. Prog. Rep. , vol.6 , pp. 1-37
    • Zycher, B.1
  • 3
    • 34447538141 scopus 로고    scopus 로고
    • High-throughput screening assays for the identification of chemical probes
    • Inglese J., et al. High-throughput screening assays for the identification of chemical probes. Nat. Chem. Biol. 3 (2007) 466-479
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 466-479
    • Inglese, J.1
  • 4
    • 32344448950 scopus 로고    scopus 로고
    • Statistical practice in high-throughput screening data analysis
    • Malo N., et al. Statistical practice in high-throughput screening data analysis. Nat. Biotechnol. 24 (2006) 167-175
    • (2006) Nat. Biotechnol. , vol.24 , pp. 167-175
    • Malo, N.1
  • 5
    • 34447502161 scopus 로고    scopus 로고
    • Image-based chemical screening
    • Carpenter A.E. Image-based chemical screening. Nat. Chem. Biol. 3 (2007) 461-465
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 461-465
    • Carpenter, A.E.1
  • 6
    • 8444223104 scopus 로고    scopus 로고
    • Multidimensional drug profiling by automated microscopy
    • Perlman Z.E., et al. Multidimensional drug profiling by automated microscopy. Science 306 (2004) 1194-1198
    • (2004) Science , vol.306 , pp. 1194-1198
    • Perlman, Z.E.1
  • 7
    • 37249026328 scopus 로고    scopus 로고
    • Integrating high-content screening and ligand-target prediction to identify mechanism of action
    • Young D.W., et al. Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nat. Chem. Biol. 4 (2008) 59-68
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 59-68
    • Young, D.W.1
  • 8
    • 9144273977 scopus 로고    scopus 로고
    • RNAi and HTS: exploring cancer by systematic loss-of-function
    • Willingham A.T., et al. RNAi and HTS: exploring cancer by systematic loss-of-function. Oncogene 23 (2004) 8392-8400
    • (2004) Oncogene , vol.23 , pp. 8392-8400
    • Willingham, A.T.1
  • 9
    • 33947395259 scopus 로고    scopus 로고
    • High-content siRNA screening
    • Krausz E. High-content siRNA screening. Mol. BioSyst. 3 (2007) 232-240
    • (2007) Mol. BioSyst. , vol.3 , pp. 232-240
    • Krausz, E.1
  • 10
    • 33748137728 scopus 로고    scopus 로고
    • Multiparametric cell cycle analysis by automated microscopy
    • Gasparri F., et al. Multiparametric cell cycle analysis by automated microscopy. J. Biomol. Screen. 11 (2006) 586-598
    • (2006) J. Biomol. Screen. , vol.11 , pp. 586-598
    • Gasparri, F.1
  • 11
    • 33747040085 scopus 로고    scopus 로고
    • Small molecule screening in the zebrafish
    • Murphey R.D., and Zon L.I. Small molecule screening in the zebrafish. Methods 39 (2006) 255-261
    • (2006) Methods , vol.39 , pp. 255-261
    • Murphey, R.D.1    Zon, L.I.2
  • 12
    • 33846524840 scopus 로고    scopus 로고
    • Integration of virtual and physical screening
    • Fara D.C., et al. Integration of virtual and physical screening. Drug Discov. Today: Technol. 3 (2006) 377-385
    • (2006) Drug Discov. Today: Technol. , vol.3 , pp. 377-385
    • Fara, D.C.1
  • 13
  • 14
    • 34249890242 scopus 로고    scopus 로고
    • High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins
    • Sauermann M., et al. High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins. J. Biomol. Screen. 12 (2007) 510-520
    • (2007) J. Biomol. Screen. , vol.12 , pp. 510-520
    • Sauermann, M.1
  • 15
    • 53049089846 scopus 로고    scopus 로고
    • Intensity calibration and automated cell cycle gating for high-throughput image-based siRNA screens of mammalian cells
    • Poon S.S.S., et al. Intensity calibration and automated cell cycle gating for high-throughput image-based siRNA screens of mammalian cells. Cytometry 73A (2008) 904-917
    • (2008) Cytometry , vol.73 A , pp. 904-917
    • Poon, S.S.S.1
  • 16
    • 50049118081 scopus 로고    scopus 로고
    • High-throughput, single-cell analysis of macrophage interactions with fluorescently labeled Bacillus anthracis spores
    • Stojkovic B., et al. High-throughput, single-cell analysis of macrophage interactions with fluorescently labeled Bacillus anthracis spores. Appl. Environ. Microbiol. 74 (2008) 5201-5210
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 5201-5210
    • Stojkovic, B.1
  • 17
    • 40049099575 scopus 로고    scopus 로고
    • High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent
    • Winter S.S., et al. High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent. J. Biomol. Screen. 13 (2008) 185-193
    • (2008) J. Biomol. Screen. , vol.13 , pp. 185-193
    • Winter, S.S.1
  • 18
    • 33646408757 scopus 로고    scopus 로고
    • MALDI-TOF MS as a label-free approach to rapid inhibitor screening
    • Greis K.D., et al. MALDI-TOF MS as a label-free approach to rapid inhibitor screening. J. Am. Soc. Mass Spectrom. 17 (2006) 815-822
    • (2006) J. Am. Soc. Mass Spectrom. , vol.17 , pp. 815-822
    • Greis, K.D.1
  • 19
    • 49449101108 scopus 로고    scopus 로고
    • High-content analysis of kinase activity in cells
    • Gasparri F. High-content analysis of kinase activity in cells. Chem. High Throughput Screen. 11 (2008) 523-536
    • (2008) Chem. High Throughput Screen. , vol.11 , pp. 523-536
    • Gasparri, F.1
  • 20
    • 33847668394 scopus 로고    scopus 로고
    • Image-based screening for the identification of novel proteasome inhibitors
    • Rickardson L., et al. Image-based screening for the identification of novel proteasome inhibitors. J. Biomol. Screen. 12 (2007) 203-210
    • (2007) J. Biomol. Screen. , vol.12 , pp. 203-210
    • Rickardson, L.1
  • 21
    • 0036198447 scopus 로고    scopus 로고
    • Development of an assay for label-free high-throughput screening of thrombin inhibitors by use of reflectometric interference spectroscopy
    • Birkert O., and Gauglitz G. Development of an assay for label-free high-throughput screening of thrombin inhibitors by use of reflectometric interference spectroscopy. Anal. Bioanal. Chem. 372 (2002) 141-147
    • (2002) Anal. Bioanal. Chem. , vol.372 , pp. 141-147
    • Birkert, O.1    Gauglitz, G.2
  • 22
    • 13844281513 scopus 로고    scopus 로고
    • Direct optical sensors: principles and selected applications
    • Gauglitz G. Direct optical sensors: principles and selected applications. Anal. Bioanal. Chem. 381 (2005) 141-155
    • (2005) Anal. Bioanal. Chem. , vol.381 , pp. 141-155
    • Gauglitz, G.1
  • 23
    • 8444236650 scopus 로고    scopus 로고
    • An optical DNA-based biosensor for the analysis of bioactive constituents with application in drug and herbal drug screening
    • Minunni M., et al. An optical DNA-based biosensor for the analysis of bioactive constituents with application in drug and herbal drug screening. Talanta 65 (2004) 578-585
    • (2004) Talanta , vol.65 , pp. 578-585
    • Minunni, M.1
  • 24
    • 37049028158 scopus 로고    scopus 로고
    • Automated, quantitative screening assay for antiangiogenic compounds using transgenic zebrafish
    • Tran T.C., et al. Automated, quantitative screening assay for antiangiogenic compounds using transgenic zebrafish. Cancer Res. 67 (2007) 11386-11392
    • (2007) Cancer Res. , vol.67 , pp. 11386-11392
    • Tran, T.C.1
  • 25
    • 49449104663 scopus 로고    scopus 로고
    • An overview of drug screening using primary and embryonic stem cells
    • Eglen R.M., et al. An overview of drug screening using primary and embryonic stem cells. Comb. Chem. High Throughput Screen. 11 (2008) 566-572
    • (2008) Comb. Chem. High Throughput Screen. , vol.11 , pp. 566-572
    • Eglen, R.M.1
  • 26
    • 44649153825 scopus 로고    scopus 로고
    • Graphical models for structured classification, with an application to interpreting images of protein subcellular location patterns
    • Chen S.-C., et al. Graphical models for structured classification, with an application to interpreting images of protein subcellular location patterns. J. Mach. Learn. Res. 9 (2008) 651-682
    • (2008) J. Mach. Learn. Res. , vol.9 , pp. 651-682
    • Chen, S.-C.1
  • 27
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 (1998) 806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1
  • 28
    • 35148885701 scopus 로고    scopus 로고
    • Assay optimization and screening of RNA-protein interactions by AlphaScreen
    • Mills N.L., et al. Assay optimization and screening of RNA-protein interactions by AlphaScreen. J. Biomol. Screen. 12 (2007) 946-955
    • (2007) J. Biomol. Screen. , vol.12 , pp. 946-955
    • Mills, N.L.1
  • 29
    • 49449105107 scopus 로고    scopus 로고
    • Industrial-style screening meets academic biology
    • Kaiser J. Industrial-style screening meets academic biology. Science 321 (2008) 764-766
    • (2008) Science , vol.321 , pp. 764-766
    • Kaiser, J.1
  • 30
    • 58149397935 scopus 로고    scopus 로고
    • Development of an inhibitor screening platform via mass spectrometry
    • Rathore R., et al. Development of an inhibitor screening platform via mass spectrometry. J. Biomol. Screen. 13 (2008) 1007-1013
    • (2008) J. Biomol. Screen. , vol.13 , pp. 1007-1013
    • Rathore, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.