MALDI-TOF MS as a Label-Free Approach to Rapid Inhibitor Screening

Journal of the American Society for Mass Spectrometry

Volumn 17, Issue 6, 2006, Pages 815-822

  Greis, Kenneth D ^a   Zhou, Songtao ^a   Burt, Thomas M ^a   Carr, Andrew N ^a   Dolan, Elizabeth ^a   Easwaran, Vijayasurian ^a   Evdokimov, Artem ^a   Kawamoto, Richard ^a   Roesgen, Jeff ^a   Davis, Gregory F ^a  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER SALTS; ELECTROSPRAY IONIZATION; MATRIX-ASSISTED LASER DESORPTION IONIZATION, TIME-OF-FLIGHT MS (MALDI-TOF MS); REPRODUCIBILITY PARAMETERS;

BIOASSAY; ENZYMES; IONIZATION; SCREENING; SUBSTRATES;

MASS SPECTROMETRY;

ENZYME INHIBITOR;

ACIDITY; ARTICLE; COMPARATIVE STUDY; COST BENEFIT ANALYSIS; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ASSAY; ENZYME MECHANISM; ENZYME SUBSTRATE; IC 50; LIQUID; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEASUREMENT; NORMAL VALUE; PARAMETER; PROCESS DEVELOPMENT; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; REPRODUCIBILITY; ROBOTICS; SCREENING; STANDARD;

ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MIXED FUNCTION OXYGENASES; PHOSPHOTRANSFERASES; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 33646408757     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2006.02.019     Document Type: Article

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