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Volumn 13, Issue 10, 2008, Pages 1007-1013

Development of an inhibitor screening platform via mass spectrometry

Author keywords

High throughput screening; Label free screening; Mass spectrometry; Matrix assisted laser desorption ionization (MALDI); Protein kinase A

Indexed keywords

ADENOSINE DIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; PHOSPHOTRANSFERASE INHIBITOR; REAGENT;

EID: 58149397935     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057108326143     Document Type: Article
Times cited : (27)

References (15)
  • 1
    • 34248545259 scopus 로고    scopus 로고
    • Mass spectrometry for enzyme assays and inhibitor screening: An emerging application in pharmaceutical research
    • Greis KD: Mass spectrometry for enzyme assays and inhibitor screening: an emerging application in pharmaceutical research. Mass Spectrom Rev 2007 ; 26: 324-339.
    • (2007) Mass Spectrom Rev , vol.26 , pp. 324-339
    • Greis, K.D.1
  • 2
    • 34948815190 scopus 로고    scopus 로고
    • Mass spectroscopy-based biochemical assays for enzyme-inhibitor screening
    • De Boer AR, Lingeman H., Niessen WM, Irth H.: Mass spectroscopy-based biochemical assays for enzyme-inhibitor screening. Trends Anal Chem 2007 ; 26: 867-883.
    • (2007) Trends Anal Chem , vol.26 , pp. 867-883
    • De Boer, A.R.1    Lingeman, H.2    Niessen, W.M.3    Irth, H.4
  • 6
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999 ; 4: 67-73.
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 8
    • 20444383823 scopus 로고    scopus 로고
    • Development of a microplate-based, electrophoretic fluorescent protein kinase a assay: Comparison with filter-binding and fluorescence polarization assay formats
    • Miick SM, Jalali S., Dwyer BP, Havens J., Thomas D., Jimenez MA,, et al. Development of a microplate-based, electrophoretic fluorescent protein kinase A assay: comparison with filter-binding and fluorescence polarization assay formats. J Biomol Screen 2005 ; 10: 329-338.
    • (2005) J Biomol Screen , vol.10 , pp. 329-338
    • Miick, S.M.1    Jalali, S.2    Dwyer, B.P.3    Havens, J.4    Thomas, D.5    Jimenez, M.A.6
  • 10
    • 45949106612 scopus 로고    scopus 로고
    • The challenge of selecting protein kinase assays for lead discovery optimization
    • Ma H., Deacon S., Horiuchi K.: The challenge of selecting protein kinase assays for lead discovery optimization. Expert Opin Drug Discov 2008 ; 3: 607-621.
    • (2008) Expert Opin Drug Discov , vol.3 , pp. 607-621
    • Ma, H.1    Deacon, S.2    Horiuchi, K.3
  • 11
    • 34547742048 scopus 로고    scopus 로고
    • High-throughput mass spectrometry screening for inhibitors of phosphatidylserine decarboxylase
    • Forbes CD, Toth JG, Ozbal CC, Lamarr WA, Pendleton JA, Rocks S.,, et al. High-throughput mass spectrometry screening for inhibitors of phosphatidylserine decarboxylase. J Biomol Screen 2007 ; 12: 628-634.
    • (2007) J Biomol Screen , vol.12 , pp. 628-634
    • Forbes, C.D.1    Toth, J.G.2    Ozbal, C.C.3    Lamarr, W.A.4    Pendleton, J.A.5    Rocks, S.6
  • 12
    • 33750287595 scopus 로고    scopus 로고
    • Monitoring enzyme reaction and screening enzyme inhibitor based on MALDI-TOF-MS platform with a matrix of oxidized carbon nanotubes
    • Hu L., Jiang G., Xu S., Pan C., Zou H.: Monitoring enzyme reaction and screening enzyme inhibitor based on MALDI-TOF-MS platform with a matrix of oxidized carbon nanotubes. J Am Soc Mass Spectrom 2006 ; 17: 1616-1619.
    • (2006) J Am Soc Mass Spectrom , vol.17 , pp. 1616-1619
    • Hu, L.1    Jiang, G.2    Xu, S.3    Pan, C.4    Zou, H.5
  • 13
    • 33744912806 scopus 로고    scopus 로고
    • A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5′diphosphate accumulation
    • Charter NW, Kauffman L., Singh R., Eglen RM: A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5′diphosphate accumulation. J Biomol Screen 2006 ; 11: 390-399.
    • (2006) J Biomol Screen , vol.11 , pp. 390-399
    • Charter, N.W.1    Kauffman, L.2    Singh, R.3    Eglen, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.