Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential

Experimental Hematology

Volumn 30, Issue 6, 2002, Pages 612-616

  McNiece, Ian K ^a   Almeida Porada, GraÇa ^b   Shpall, Elizabeth J ^a   Zanjani, Esmail ^b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF NEVADA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; STEM CELL FACTOR;

ARTICLE; BLOOD CELL; BONE MARROW; CELL ACTIVITY; CELL CULTURE; CELL TRANSPLANTATION; CONTROLLED STUDY; EVALUATION; FETUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RECIPIENT; SHEEP; STEM CELL; UMBILICAL CORD BLOOD; XENOGRAFT;

ANIMALS; FEMALE; FETAL BLOOD; FETUS; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; PREGNANCY; SHEEP; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

ANIMALIA; OVIS ARIES;

EID: 0036284776     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(02)00805-6     Document Type: Article

References (15)

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3. Placenta blood as a source of hematopoietic stem cells for transplantation into unrelated recipients
4. + hematopoietic stem cells
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6. The human/sheep xenograft model: A large animal model of human hematopoiesis
7. Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers
8. Frequency analysis of human primitive haematopoietic stem cell subsets using a cobblestone area forming cell assay
9. Colony-forming cells with high proliferative potential (HPP-CFC)
10. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
11. Increased expansion and differentiation of cord blood products using a two step expansion culture
12. Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep
13. Ex vivo expanded peripheral blood progenitor cells provide rapid neutrophil recovery after high dose chemotherapy in breast cancer patients
14. Transplantation of adult and pediatric cancer patients with cord blood progenitors expanded ex vivo
15. Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system