Mechanisms of p,p′-DDE-induced apoptosis in human peripheral blood mononuclear cells

Toxicology in Vitro

Volumn 23, Issue 6, 2009, Pages 1000-1006

  Alegría Torres, Jorge A ^a   Díaz Barriga, Fernando ^a   Gandolfi, A Jay ^b   Pérez Maldonado, Iván N ^a  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Apoptosis; p,p DDE; Pro inflammatory state

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; CASPASE 3; CASPASE 8; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BID;

ADULT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; INFLAMMATION; NORMAL HUMAN; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; UBIQUITINATION;

ADULT; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BIOLOGICAL MARKERS; CASPASES; DICHLORODIPHENYL DICHLOROETHYLENE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INFLAMMATION; INSECTICIDES; LEUKOCYTES, MONONUCLEAR; POLY(ADP-RIBOSE) POLYMERASES; UBIQUITINATION; YOUNG ADULT;

EID: 68049142967     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.06.021     Document Type: Article

References (49)

1. Adams J.M., and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281 (1998) 1322-1326
2. ATSDR, 2002. Toxicological Profile for DDT/DDE/DDD, Agency for Toxic Substances and Disease Registry, US Public Health Service, Atlanta, GA.
3. Binelli A., Riva C., Coqni D., and Provini A. Genotoxic effects of p, p′-DDT (1,1,1-trichloro-2,2-bis-(chlorophenyl)ethane) and its metabolites in Zebra mussel (D. Polymorpha) by SCGE assay and micronucleus test. Environ. Mol. Mutagen 49 (2008) 406-415
4. Brown N.M., Torres A.S., Doan P.E., and ÓHalloran T.V. Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu, Zn superoxide dismutase. Proc. Natl. Acad. Sci. USA 101 (2004) 5518-5523
5. Bustamante J., Nutt L., Orrenius S., and Gogvadze V. Arsenic stimulates release of cytochrome c from isolated mitochondria via induction of mitochondrial permeability transition. Toxicol. Appl. Pharmacol. 207 (2005) 110-116
6. Chowdhury R., Chowdhury S., Roychoudhury P., Mandal C., and Chaudhuri K. Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione trough ROS generation, p38 signaling and p53 activation. Apoptosis 14 (2009) 108-123
7. Clifford B., Beljin M., Stark G.R., and Taylor W.R. G2 arrest in response to topoisomerase II inhibitors: the role of p53. Cancer Res. 63 (2003) 4074-4081
8. Colosio C., Tiramani M., and Maroni M. Neurobehavioral effects of pesticides: state of the art. Neurotoxicology 24 (2003) 577-591
9. De Jager C., Farias P., Barraza-Villarreal A., Avila M.H., Ayotte P., Dewailly E., Dombrowski C., Rousseau F., Sanchez V.D., and Bailey J.L. Reduced seminal parameters associated with environmental DDT exposure and p,p'-DDE concentrations in men in Chiapas, Mexico: a cross-sectional study. J. Androl. 27 (2006) 16-27
10. De la Fuente H., Portals-Pérez D., Baranda L., Díaz-Barriga F., Saavedra-Alanís V., Layseca E., and González-Amaro R. Effect of arsenic, cadmium and lead on the induction of apoptosis of normal human mononuclear cells. Clin. Exp. Immunol. 129 (2002) 69-77
11. Deng L., Wang C., Spencer E., Yang L., Braun A., You J., Slaughter C., Pickart C., and Chen Z.J. Activation of the IkB kinase complex by TRAF6 requires a dimeric ubiquitin conjugating enzyme complex and the a unique polyubiquitin chain. Cell 103 (2000) 351-361
12. Eblin K.E., Bredfeldt T.G., Buffington S., and Gandolfi A.J. Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis. Toxicol. Sci. 95 (2007) 321-330
13. Ennaceur S., Ridha D., and Marcos R. Genotoxicity of the organochlorine pesticides 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and hexachlorobenzene (HCB) in cultured human lymphocytes. Chemosphere 71 (2008) 1335-1339
14. Frigo D.E., Vigh K.A., Struckhoff A.P., Elliott S., Beckman B.S., Burow M.E., and McLachlan J.A. Xenobiotic-induced TNF-α expression and apoptosis through the p38 MAPK signaling pathway. Toxicol. Lett. 155 (2005) 227-238
15. Greenlee A.R., Quail C.A., and Berg R.L. The antiestrogen ICI 182, 780 abolishes developmental injury for murine embryos exposed in vitro to o, p′-DDT. Reprod. Toxicol. 14 (1999) 225-234
16. Gross A., Yin X.M., Wang K., Wei M.C., Jockel J., Milliman C., Erdjument-Bromage H., Tempst P., and Korsmeyer S.J. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J. Biol. Chem. 274 (1999) 1156-1163
17. Haupt S., Berger M., Goldberg Z., and Haupt Y. Apoptosis - the p53 network. J. Cell. Sci. 116 Pt 20 (2003) 4077-4085
18. Herrera-Portugal C., Ochoa H., Franco-Sánchez G., Yáñez L., and Díaz-Barriga F. Environmental pathways of exposure to DDT for children living in a malarious area of Chiapas, Mexico. Environ. Res. 99 (2005) 158-163
19. Kanda N., and Watanabe S. 17β-Estradiol inhibits oxidative stress-induced apoptosis in keratinocytes by promoting Bcl-2 expression. J. Invest. Dermatol. 121 (2003) 1500-1509
20. Kelner M.J., McLenithan J.C., and Anders M.W. Thiol stimulation of the cytochrome P-450-dependent reduction of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD). Biochem. Pharmacol. 35 (1986) 1805-1807
21. Kim J.Y., Choi C.Y., Lee K.J., Shin D.W., Jung K.S., Chung Y.C., Lee S.S., Shin J.G., and Jeong H.G. Induction of inducible nitric oxide synthase and proinflammatory cytokines expression by o, p′-DDT in macrophages. Toxicol. Lett. 147 (2004) 261-269
22. Kitamura S., Shimizu Y., Shiraga Y., Yoshida M., Sugihara K., and Ohta S. Reductive metabolism of p, p′-DDT and o, p′-DDT by rat liver cytochrome P450. Drug Metab. Dispos. 30 (2002) 113-118
23. Lee J.C., and Peter M.E. Regulation of apoptosis by ubiquitination. Immunol. Rev. 193 (2003) 39-47
24. Li J., Li N., Ma M., Giesy J.P., and Wang Z. In vitro profiling of the endocrine disrupting potency of organochlorine pesticides. Toxicol. Lett. 183 (2008) 65-71
25. Li H., Zhu H., Xu C.J., and Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94 (1998) 491-501
26. López-Carrillo L., Torres-Arreola L., Torres-Sánchez L., Espinosa-Torres F., Jiménez C., Cebrián M., Waliszewski S., and Saldate O. Is DDT use a public health problem in Mexico?. Environ. Health Perspect. 104 (1996) 584-588
27. Martinou J.C. Apoptosis. Key to the mitochondrial gate. Nature 399 (1999) 411-412
28. Marzo I., Brenner C., Zamzami N., Jurgensmeier J.M., Susin S.A., Vieira H.L., Prevost M.C., Xie Z., Matsuyama S., Reed J.C., and Kroemer G. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281 (1998) 2027-2031
29. Morgan D.P., and Roan C.C. Absorption, storage and metabolic conversion of ingested DDT and DDT metabolites in man. Arch. Environ. Health 22 (1971) 301-308
30. Mosmann T. Rapid colorimetric assays for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
31. Narita M., Shimizu S., Ito T., Chittenden T., Lutz R.J., Matsuda H., and Tsujimoto Y. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc. Natl. Acad. Sci. USA 95 (1998) 14681-14686
32. Noor R., Mittal S., and Iqbal J. Superoxide dismutase-applications and relevance to human diseases. Med. Sci. Monit. 8 (2002) RA210-RA215
33. Pérez-Maldonado I.N., Díaz-Barriga F., De la Fuente H., González-Amaro R., Calderón J., and Yáñez L. DDT induces apoptosis in human mononuclear cells in vitro and is associated with increased apoptosis in exposed children. Environ. Res. 94 (2004) 38-46
34. Pérez-Maldonado I.N., Herrera C., Batres L.E., González-Amaro R., Díaz-Barriga F., and Yáñez L. DDT-induced oxidative damage in human blood mononuclear cells. Environ. Res. 98 (2005) 117-184
35. Pérez-Maldonado I.N., Athanasiadou M., Yánez L., González-Amaro R., Bergman A., and Díaz-Barriga F. DDE-induced apoptosis in children exposed to the DDT metabolite. Sci. Total Environ. 370 (2006) 343-351
36. Ribas-Fitó N., Cardo E., Sala M., Eulàlia de Muga M., Mazón C., Verdú A., Kogevinas M., Grimalt J.O., and Sunyer J. Breastfeeding, exposure to organochlorine compounds, and neurodevelopment in infants. Pedriatrics 111 (2003) 580-585
37. Stapleton D.H. The dawn of DDT and its experimental use by the Rockefeller Foundation in Mexico, 1943-1952. Parassitologia 40 (1998) 149-158
38. Strasser A., Jost P.J., and Nagata S. The many roles of FAS receptor signaling in the immune system. Immunity 30 (2009) 180-192
39. Sun S.C., Maggirwar S.B., and Harhaj E. Activation of NFkB by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites. J. Biol. Chem. 270 (1995) 18347-18351
40. Tebourbi O., Rhouma K.B., and Sakly M. DDT induces apoptosis in rat thymocytes. Bull. Environ. Contam. Toxicol. 61 (1998) 216-223
41. Trejo-Acevedo A., Díaz-Barriga F., Carrizales L., Domínguez G., Costilla R., Ize-Lema I., Yarto-Ramírez M., Gavilán-García A., Mejía-Saavedra J., and Pérez-Maldonado I.N. Exposure assessment of persistent organic pollutants and metals in Mexican children. Chemosphere 74 (2009) 974-980
42. Turusov V., Rakitsky V., and Tomatis L. Dichlorodiphenyltrichloroethane (DDT): ubiquity, persistence and risks. Environ. Health Perspect. 110 (2002) 125-128
43. Van Zwieten L., Ayres M.R., and Morris S.G. Influence of arsenic co-contamination on DDT breakdown and microbial activity. Environ. Pollut. 124 (2003) 331-339
44. Vane J.R., Bakhle Y.S., and Botting R.M. Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol. 38 (1998) 97-120
45. Wilkie G.S., Dickson K.S., and Gray N.K. Regulation of mRNA translation by 5′- and 3′-UTR-binding factors. Trends Biochem. Sci. 28 (2003) 182-188
46. Wray G.A., Hahn M.W., Abouheif E., Balhoff J.P., Pizer M., Rockman M.V., and Romano L.A. The evolution of transcriptional regulation in eukaryotes. Mol. Biol. Evol. 20 (2003) 1377-1419
47. Yamada H., Tada-Oikawa S., Uchida A., and Kawanishi S. TRAIL causes cleavage of Bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB Cells. Biochem. Biophys. Res. Commun. 265 (1999) 130-133
48. Yáñez L., Borja-Aburto V., Rojas E., De la Fuente H., González-Amaro R., Gómez H., Jongitud A., and Díaz-Barriga F. DDT induces DNA damage in blood cells. Studies in vitro and in women chronically exposed to this insecticide. Environ. Res. 94 (2004) 18-24
49. Yao J., Kim T.W., Qin J., Jiang Z., Qian Y., Xiao H., Lu Y., Qian W., Gulen M.F., Sizemore N., DiDonato J., Sato S., Akira S., Su B., and Li X. Interleukin-1(IL-1)-induced TAK1-dependent versus MEKK3-dependent NFkB activation pathways bifurcate at IL-1 receptor-associated kinase modification. J. Biol. Chem. 282 (2007) 6075-6089