Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione through ROS generation, p38 signaling and p53 activation

Apoptosis

Volumn 14, Issue 1, 2009, Pages 108-123

  Chowdhury, Rajdeep ^a   Chowdhury, Suchandra ^a   Roychoudhury, Paromita ^a   Mandal, Chitra ^a   Chaudhuri, Keya ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

AP 1; Apoptosis; Melanoma; Menadione; P38; P53; Reactive oxygen species (ROS); Sodium arsenite (NaAsO2)

Indexed keywords

ANTIFIBRINOLYTIC AGENT; ARSENIC; ARSENITE SODIUM; ARSENOUS ACID DERIVATIVE; MENADIONE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SODIUM DERIVATIVE; TP53 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; GENE EXPRESSION REGULATION; HUMAN; MALE; MELANOMA; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ANTIFIBRINOLYTIC AGENTS; APOPTOSIS; ARSENIC; ARSENITES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MELANOMA; MICE; MICE, INBRED BALB C; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SODIUM COMPOUNDS; TUMOR SUPPRESSOR PROTEIN P53; VITAMIN K 3;

EID: 58949095658     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0284-8     Document Type: Article

References (54)

1. Jurcic JG, Soignet SL, Maslak AP (2007) Diagnosis and treatment of acute promyelocytic leukemia. Curr Oncol Rep 9:337-344. doi:10.1007/s11912-007-0045-9 (Pubitemid 47377064)
2. Chou WC, Dang CV (2005) Acute promyelocytic leukemia: recent advances in therapy and molecular basis of response to arsenic therapies. Curr Opin Hematol 12:1-6. doi:10.1097/01. moh.0000148552.93303.45
3. Cheung WM, Chu PW, Kwong YL (2007) Effects of arsenic trioxide on the cellular proliferation, apoptosis and differentiation of human neuroblastoma cells. Cancer Lett 246:122-128. doi: 10.1016/j.canlet.2006.02.009 (Pubitemid 44959385)
4. Shen ZY, Zhang Y, Chen JY et al (2004) Intratumoral injection of arsenic to enhance antitumor efficacy in human esophageal carcinoma cell xenografts. Oncol Rep 11:155-159
5. Huang RQ, Gao SF, Wang WL, Staunton S, Wang G (2006) Soil arsenic availability and the transfer of soil arsenic to crops in suburban areas in Fujian Province, southeast China. Sci Total Environ 368:531-541. doi:10.1016/j.scitotenv.2006.03.013 (Pubitemid 44148785)
6. Bode AM, Dong Z (2002) The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects. Crit Rev Oncol Hematol 42:5-24. doi:10.1016/S1040-8428(01) 00215-3 (Pubitemid 34229146)
7. Engel RH, Evens AM (2006) Oxidative stress and apoptosis: a new treatment paradigm in cancer. Front Biosci 11:300-312. doi: 10.2741/1798 (Pubitemid 43253493)
8. Kang YH, Yi MJ, Kim MJ et al (2004) Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase- 1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res 64:8960-8967. doi:10.1158/0008-5472. CAN-04-1830
9. Yang J, Li H, Chen YY et al (2004) Anthraquinones sensitize tumor cells to arsenic cytotoxicity in vitro and in vivo via reactive oxygen species-mediated dual regulation of apoptosis. Free Radic Biol Med 37:2027-2041. doi:10.1016/j.freeradbiomed.2004.09. 016 (Pubitemid 39491322)
10. Yi J, Yang J, He R et al (2004) Emodin enhances arsenic trioxideinduced apoptosis via generation of reactive oxygen species and inhibition of survival signaling. Cancer Res 64:108-116. doi: 10.1158/0008-5472.CAN-2820-2 (Pubitemid 38114088)
11. Kassouf W, Highshaw R, Nelkin GM, Dinney CP, Kamat AM (2006) Vitamins C and K3 sensitize human urothelial tumors to gemcitabine. J Urol 176:1642-1647. doi:10.1016/j.juro.2006. 06.042 (Pubitemid 44307224)
12. Hitomi M, Yokoyama F, Kita Y et al (2005) Antitumor effects of vitamins K1, K2 and K3 on hepatocellular carcinoma in vitro and in vivo. Int J Oncol 26:713-720
13. Thor H, Smith MT, Hartzell P, Bellomo G, Jewell SA, Orrenius S (1982) The metabolism of menadione (2-methyl-1, 4-naphthoquinone) by isolated hepatocytes A study of the implications of oxidative stress in intact cells. J Biol Chem 257:12419-12425 (Pubitemid 13180138)
14. Ivanov VN, Bhoumik A, Ronai Z (2003) Death receptors and melanoma resistance to apoptosis. Oncogene 22:3152-3161. doi: 10.1038/sj.onc.1206456 (Pubitemid 36713767)
15. Soengas MS, Lowe SW (2003) Apoptosis and melanoma chemoresistance. Oncogene 22:3138-3151. doi:10.1038/sj.onc. 1206454 (Pubitemid 36713766)
16. Serrone L, Zeuli M, Sega FM, Cognetti F (2000) Dacarbazinebased chemotherapy for metastatic melanoma: thirty-year experience overview. J Exp Clin Cancer Res 19:21-34 (Pubitemid 30305516)
17. Tsao H, Atkins MB, Sober AJ (2004) Management of cutaneous melanoma. N Engl J Med 351:998-1012. doi:10.1056/NEJMra 041245 (Pubitemid 39166263)
18. Kim KB, Bedikian AY, Camacho LH, Papadopoulos NE, McCullough C (2005) A phase II trial of arsenic trioxide in patients with metastatic melanoma. Cancer 104:1687-1692 (Pubitemid 41437432)
19. Panka DJ, Atkins MB, Mier JW (2006) Targeting the mitogenactivated protein kinase pathway in the treatment of malignant melanoma. Clin Cancer Res 12:2371s-2375s. doi:10.1158/1078- 0432.CCR-05-2539
20. Chowdhury R, Dutta A, Chaudhuri SR, Sharma N, Giri AK, Chaudhuri K (2008) In vitro and in vivo reduction of sodium arsenite induced toxicity by aqueous garlic extract. Food Chem Toxicol 46:740-751. doi:10.1016/j.fct.2007.09.108 (Pubitemid 350297554)
21. Miller WH Jr., Schipper HM, Lee JS, Singer J, Waxman S (2002) Mechanisms of action of arsenic trioxide. Cancer Res 62:3893-3903 (Pubitemid 34792653)
22. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR (1982) Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal Biochem 126:131-138. doi: 10.1016/0003-2697(82)90118-X (Pubitemid 13203451)
23. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126. doi:10.1016/S0076-6879(84)05016-3
24. Misra HP, Fridovich I (1972) The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247:3170-3175
25. Wilber CG, Del Pomo M (1949) Comparative study of lipids in whole carcasses of Arctic and non-Arctic fish. Proc Soc Exp Biol Med 72:418-420
26. Haraguchi M, Torii S, Matsuzawa S et al (2000) Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2. J Exp Med 191:1709-1720. doi:10.1084/ jem.191.10.1709 (Pubitemid 30332454)
27. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC (1994) Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371:346-347. doi: 10.1038/371346a0 (Pubitemid 24300618)
28. Hayashi T, Hideshima T, Akiyama M et al (2002) Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment. Mol Cancer Ther 1:851-860
29. McNeely SC, Belshoff AC, Taylor BF et al (2008) Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest. Toxicol Appl Pharmacol 229:252-261. doi:10.1016/j.taap.2008.01. 020
30. McNeely SC, Taylor BF, States JC (2008) Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent. Toxicol Appl Pharmacol 231:61-67. doi:10.1016/j.taap.2008.03.020
31. Nordenson I, Beckman L (1991) Is the genotoxic effect of arsenic mediated by oxygen free radicals? Hum Hered 41:71-73. doi: 10.1159/000153979
32. Liu SX, Athar M, Lippai I, Waldren C, Hei TK (2001) Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity. Proc Natl Acad Sci USA 98:1643-1648. doi:10.1073/ pnas.031482998 (Pubitemid 32165551)
33. Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-157. doi:10.1016/S0092-8674 (00)80085-9 (Pubitemid 26256586)
34. Alnemri ES, Livingston DJ, Nicholson DW et al (1996) Human ICE/CED-3 protease nomenclature. Cell 87:171. doi:10.1016/ S0092-8674(00)81334-3
35. Soengas MS, Capodieci P, Polsky D et al (2001) Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 409:207-211. doi:10.1038/35051606 (Pubitemid 32144287)
36. Sun Y, Orrenius S, Pervaiz S, Fadeel B (2005) Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance. Blood 105:4070-4077. doi:10.1182/blood-2004-10-4075 (Pubitemid 40656157)
37. Leaman DW, Chawla-Sarkar M, Vyas K et al (2002) Identification of X-linked Inhibitor of Apoptosis-associated Factor-1 as an Interferon-stimulated Gene That Augments TRAIL Apo2Linduced Apoptosis. J Biol Chem 277:28504-28511. doi:10.1074/ jbc.M204851200 (Pubitemid 41079276)
38. Hsu TC, Young MR, Cmarik J, Colburn NH (2000) Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)- dependent transcriptional events in carcinogenesis. Free Radic Biol Med 28:1338-1348. doi:10.1016/S0891-5849(00) 00220-3 (Pubitemid 30621478)
39. Mathas S, Lietz A, Janz M et al (2003) Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis. Blood 102:1028-1034. doi:10.1182/blood-2002-04-1154 (Pubitemid 36917800)
40. Zhou LF, Zhu Y, Cui XF, Xie WP, Hu AH, Yin KS (2006) Arsenic trioxide, a potent inhibitor of NF-kappaB, abrogatesallergen-induced airway hyper responsiveness and inflammation. Respir Res 7:146. doi:10.1186/1465-9921-7-146
41. Bulavin DV, Saito S, Hollander MC et al (1999) Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J 18:6845-6854. doi:10.1093/emboj/18.23.6845
42. Yu J, Qian H, Li Y et al (2007) Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo. Gynecol Oncol 106:400-406. doi:10.1016/ j.ygyno.2007.04.016 (Pubitemid 47096659)
43. Baysan A, Yel L, Gollapudi S, Su H, Gupta S (2007) Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. Int J Oncol 30:313-318
44. Woo SH, Park IC, Park MJ et al (2002) Arsenic trioxide induces apoptosis through a reactive oxygen species-dependent pathway and loss of mitochondrial membrane potential in HeLa cells. Int J Oncol 21:57-63
45. Burdon RH (1996) Control of cell proliferation by reactive oxygen species. Biochem Soc Trans 24:1028-1032
46. Criddle DN, Gillies S, Baumgartner-Wilson HK et al (2006) Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells. J Biol Chem 281:40485-40492. doi:10.1074/jbc.M607704200 (Pubitemid 46041851)
47. Finkel T (2001) Reactive oxygen species and signal transduction. IUBMB Life 52:3-6. doi:10.1080/15216540252774694 (Pubitemid 33769662)
48. Sauer H, Wartenberg M, Hescheler J (2001) Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 11:173-186. doi:10.1159/ 000047804 (Pubitemid 32786086)
49. Levkau B, Scatena M, Giachelli CM, Ross R, Raines EW (1999) Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop. Nat Cell Biol 1:227-233. doi:10.1038/12050 (Pubitemid 129500942)
50. Karin M, Lin A (2002) NF-kappaB at the crossroads of life and death. Nat Immunol 3:221-227. doi:10.1038/ni0302-221 (Pubitemid 34213423)
51. Keller D, Zeng X, Li X et al (1999) The p38 MAPK inhibitor SB203580 alleviates ultraviolet-induced phosphorylation at serine 389 but not serine 15 and activation of p53. Biochem Biophys Res Commun 261:464-471. doi:10.1006/bbrc.1999.1023 (Pubitemid 29392499)
52. Huang C, Ma WY, Li J, Dong Z (1999) Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway. Cancer Res 59:3053-3058 (Pubitemid 29316000)
53. Huang C, Ma WY, Li J, Goranson A, Dong Z (1999) Requirement of Erk, but not JNK, for arsenite-induced cell transformation. J Biol Chem 274:14595-14601. doi:10.1074/jbc. 274.21.14595
54. Huang C, Ma WY, Maxiner A, Sun Y, Dong Z (1999) p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem 274:12229-12235. doi:10.1074/jbc.274.18.12229 (Pubitemid 29215446)