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Volumn 27, Issue 7, 2009, Pages 1616-1624

Restoration of Runx1 expression in the Tie2 cell compartment rescues definitive hematopoietic stem cells and extends life of Runx1 knockout animals until birth

Author keywords

AGM region; Embryo; HSC; Runx1; Yolk sac

Indexed keywords

ANGIOPOIETIN RECEPTOR; CRE RECOMBINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR RUNX1;

EID: 68049124509     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.71     Document Type: Article
Times cited : (36)

References (64)
  • 1
    • 0037217195 scopus 로고    scopus 로고
    • AML1 interconnected pathways of leukemogenesis
    • Michaud J, Scott HS, Escher R. AML1 interconnected pathways of leukemogenesis. Cancer Invest 2003;21:105-136.
    • (2003) Cancer Invest , vol.21 , pp. 105-136
    • Michaud, J.1    Scott, H.S.2    Escher, R.3
  • 2
    • 0036137654 scopus 로고    scopus 로고
    • Runx1/AML1 in leukemia: Disrupted association with diverse protein partners
    • DOI 10.1016/S0145-2126(01)00128-X, PII S014521260100128X
    • Perry C, Eldor A, Soreq H. Runx1/AML1 in leukemia: disrupted association with diverse protein partners. Leuk Res 2002;26:221-228. (Pubitemid 34037018)
    • (2002) Leukemia Research , vol.26 , Issue.3 , pp. 221-228
    • Perry, C.1    Eldor, A.2    Soreq, H.3
  • 4
    • 2942547444 scopus 로고    scopus 로고
    • Core-binding factors in hematopoiesis and immune function
    • de Bruijn MF, Speck NA. Core-binding factors in hematopoiesis and immune function. Oncogene 2004;23:4238-4248.
    • (2004) Oncogene , vol.23 , pp. 4238-4248
    • De Bruijn, M.F.1    Speck, N.A.2
  • 5
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • DOI 10.1016/S0092-8674(00)80986-1
    • Okuda T, van Deursen J, Hiebert SW et al. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 1996;84:321-330. (Pubitemid 26042836)
    • (1996) Cell , vol.84 , Issue.2 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 8
    • 43249108398 scopus 로고    scopus 로고
    • Runx1 is involved in primitive erythropoiesis in the mouse
    • Yokomizo T, Hasegawa K, Ishitobi H et al. Runx1 is involved in primitive erythropoiesis in the mouse. Blood 2008;111:4075-4080.
    • (2008) Blood , vol.111 , pp. 4075-4080
    • Yokomizo, T.1    Hasegawa, K.2    Ishitobi, H.3
  • 10
    • 32544445732 scopus 로고    scopus 로고
    • AML1 deletion in adult mice causes splenomegaly and lymphomas
    • DOI 10.1038/sj.onc.1209136, PII 1209136
    • Putz G, Rosner A, Nuesslein I et al. AML1 deletion in adult mice causes splenomegaly and lymphomas. Oncogene 2006;25:929-939. (Pubitemid 43237711)
    • (2006) Oncogene , vol.25 , Issue.6 , pp. 929-939
    • Putz, G.1    Rosner, A.2    Nuesslein, I.3    Schmitz, N.4    Buchholz, F.5
  • 13
    • 0033405452 scopus 로고    scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J, Robertson S, Kennedy M et al. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 1999;126:5073-5084. (Pubitemid 30000420)
    • (1999) Development , vol.126 , Issue.22 , pp. 5073-5084
    • Palis, J.1    Robertson, S.2    Kennedy, M.3    Wall, C.4    Keller, G.5
  • 14
    • 0001204999 scopus 로고
    • Ontogeny of the mouse hematopoietic system
    • Medvinsky A. Ontogeny of the mouse hematopoietic system. Semin Dev Biol 1993;4:333-340.
    • (1993) Semin Dev Biol , vol.4 , pp. 333-340
    • Medvinsky, A.1
  • 15
    • 0028467947 scopus 로고
    • Development of hematopoietic stem cell activity in the mouse embryo
    • DOI 10.1016/1074-7613(94)90081-7
    • Muller AM, Medvinsky A, Strouboulis J et al. Development of hematopoietic stem cell activity in the mouse embryo. Immunity 1994;1:291-301. (Pubitemid 2114862)
    • (1994) Immunity , vol.1 , Issue.4 , pp. 291-301
    • Muller, A.M.1    Medvinsky, A.2    Strouboulis, J.3    Grosveld, F.4    Dzierzak, E.5
  • 16
    • 0034214284 scopus 로고    scopus 로고
    • Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo
    • de Bruijn MF, Speck NA, Peeters MC et al. Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo. EMBO J. 2000;19:2465-2474.
    • (2000) EMBO J , vol.19 , pp. 2465-2474
    • De Bruijn, M.F.1    Speck, N.A.2    Peeters, M.C.3
  • 17
    • 14644437071 scopus 로고    scopus 로고
    • The murine placenta contains hematopoietic stem cells within the vascular labyrinth region
    • DOI 10.1016/j.devcel.2005.02.001, PII S1534580705000481
    • Ottersbach K, Dzierzak E. The murine placenta contains hematopoietic stem cells within the vascular labyrinth region. Dev Cell 2005;8:377-387. (Pubitemid 40309808)
    • (2005) Developmental Cell , vol.8 , Issue.3 , pp. 377-387
    • Ottersbach, K.1    Dzierzak, E.2
  • 18
    • 14644416569 scopus 로고    scopus 로고
    • The placenta is a niche for hematopoietic stem cells
    • DOI 10.1016/j.devcel.2004.12.016, PII S153458070400468X
    • Gekas C, Dieterlen-Lievre F, Orkin SH et al. The placenta is a niche for hematopoietic stem cells. Dev Cell 2005;8:365-375. (Pubitemid 40309807)
    • (2005) Developmental Cell , vol.8 , Issue.3 , pp. 365-375
    • Gekas, C.1    Dieterlen-Lievre, F.2    Orkin, S.H.3    Mikkola, H.K.A.4
  • 19
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • DOI 10.1016/S0092-8674(00)80165-8
    • Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996;86:897-906. (Pubitemid 26336794)
    • (1996) Cell , vol.86 , Issue.6 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 20
    • 0036848557 scopus 로고    scopus 로고
    • Quantitative developmental anatomy of definite haematopoietic stem cells/long-term repopulating units (HSC/RUs): Role of the aorta-gonad- mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver
    • Kumaravelu P, Hook L, Morrison AM et al. Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver. Development 2002;129:4891-4899. (Pubitemid 35355907)
    • (2002) Development , vol.129 , Issue.21 , pp. 4891-4899
    • Kumaravelu, P.1    Hook, L.2    Morrison, A.M.3    Ure, J.4    Zhao, S.5    Zuyev, S.6    Ansell, J.7    Medvinsky, A.8
  • 21
    • 33645766285 scopus 로고    scopus 로고
    • Multifunctional reversible knockout/reporter system enabling fully functional reconstitution of the AML1/Runx1 locus and rescue of hematopoiesis
    • Samokhvalov IM, Thomson AM, Lalancette C et al. Multifunctional reversible knockout/reporter system enabling fully functional reconstitution of the AML1/Runx1 locus and rescue of hematopoiesis. Genesis 2006;44:115-121.
    • (2006) Genesis , vol.44 , pp. 115-121
    • Samokhvalov, I.M.1    Thomson, A.M.2    Lalancette, C.3
  • 22
    • 0042071264 scopus 로고    scopus 로고
    • Labeling of hematopoietic stem and progenitor cells in novel activatable EGFP reporter mice
    • DOI 10.1002/gene.10209
    • Gilchrist DS, Ure J, Hook L et al. Labeling of hematopoietic stem and progenitor cells in novel activatable EGFP reporter mice. Genesis 2003;36:168-176. (Pubitemid 36959349)
    • (2003) Genesis , vol.36 , Issue.3 , pp. 168-176
    • Gilchrist, D.S.1    Ure, J.2    Hook, L.3    Medvinsky, A.4
  • 24
    • 0024356535 scopus 로고
    • An in situ transgenic enzyme marker for the midgestation mouse embryo and the visualization of inner cell mass clones during early organogenesis
    • Beddington RS, Morgernstern J, Land H et al. An in situ transgenic enzyme marker for the midgestation mouse embryo and the visualization of inner cell mass clones during early organogenesis. Development 1989;106:37-46. (Pubitemid 19150669)
    • (1989) Development , vol.106 , Issue.1 , pp. 37-46
    • Beddington, R.S.P.1    Morgernstern, J.2    Land, H.3    Hogan, A.4
  • 25
    • 33745954150 scopus 로고    scopus 로고
    • The differentiation program of embryonic definitive hematopoietic stem cells is largely alpha4 integrin independent
    • DOI 10.1182/blood-2005-10-4209
    • Gribi R, Hook L, Ure J et al. The differentiation program of embryonic definitive hematopoietic stem cells is largely alpha4 integrin independent. Blood 2006;108:501-509. (Pubitemid 44061348)
    • (2006) Blood , vol.108 , Issue.2 , pp. 501-509
    • Gribi, R.1    Hook, L.2    Ure, J.3    Medvinsky, A.4
  • 28
    • 3142780543 scopus 로고    scopus 로고
    • AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons
    • DOI 10.1073/pnas.0400768101
    • Theriault FM, Roy P, Stifani S. AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons. Proc Natl Acad Sci U S A 2004;101:10343-10348. (Pubitemid 38924927)
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , Issue.28 , pp. 10343-10348
    • Theriault, F.M.1    Roy, P.2    Stifani, S.3
  • 29
    • 14244255580 scopus 로고    scopus 로고
    • Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system
    • DOI 10.1523/JNEUROSCI.5108-04.2005
    • Theriault FM, Nuthall HN, Dong Z et al. Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system. J Neurosci 2005;25:2050-2061. (Pubitemid 40289410)
    • (2005) Journal of Neuroscience , vol.25 , Issue.8 , pp. 2050-2061
    • Theriault, F.M.1    Nuthall, H.N.2    Dong, Z.3    Lo, R.4    Barnabe-Heider, F.5    Miller, F.D.6    Stifani, S.7
  • 30
    • 0027368264 scopus 로고
    • Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system
    • published erratum appears in Proc Natl Acad Sci U S A 1993;90:12056
    • Sato TN, Qin Y, Kozak CA et al. Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system [published erratum appears in Proc Natl Acad Sci U S A 1993;90:12056]. Proc Natl Acad Sci U S A 1993;90:9355-9358.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 9355-9358
    • Sato, T.N.1    Qin, Y.2    Kozak, C.A.3
  • 32
    • 0034551745 scopus 로고    scopus 로고
    • Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver
    • Hsu HC, Ema H, Osawa M et al. Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver. Blood 2000;96:3757-3762.
    • (2000) Blood , vol.96 , pp. 3757-3762
    • Hsu, H.C.1    Ema, H.2    Osawa, M.3
  • 33
    • 46449109730 scopus 로고    scopus 로고
    • Endothelial-specific ablation of serum response factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality
    • Holtz ML, Misra RP. Endothelial-specific ablation of serum response factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality. BMC Dev Biol 2008;8:65.
    • (2008) BMC Dev Biol , vol.8 , pp. 65
    • Holtz, M.L.1    Misra, R.P.2
  • 34
    • 52649091181 scopus 로고    scopus 로고
    • Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression
    • Zhu BM, McLaughlin SK, Na R et al. Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression. Blood 2008;112:2071-2080.
    • (2008) Blood , vol.112 , pp. 2071-2080
    • Zhu, B.M.1    McLaughlin, S.K.2    Na, R.3
  • 35
    • 47949124470 scopus 로고    scopus 로고
    • Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches
    • Yoon MJ, Koo BK, Song R et al. Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches. Mol Cell Biol Aug 2008;28:4794-4804.
    • (2008) Mol Cell Biol Aug , vol.28 , pp. 4794-4804
    • Yoon, M.J.1    Koo, B.K.2    Song, R.3
  • 36
    • 1642489095 scopus 로고    scopus 로고
    • Tie2-Cre-Induced Inactivation of a Conditional Mutant Nf1 Allele in Mouse Results in a Myeloproliferative Disorder that Models Juvenile Myelomonocytic Leukemia
    • DOI 10.1203/01.PDR.0000113462.98851.2E
    • Gitler AD, Kong Y, Choi JK et al. Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia. Pediatr Res 2004;55:581-584. (Pubitemid 38405843)
    • (2004) Pediatric Research , vol.55 , Issue.4 , pp. 581-584
    • Gitler, A.D.1    Kong, Y.2    Choi, J.K.3    Zhu, Y.4    Pear, W.S.5    Epstein, J.A.6
  • 37
    • 18544364934 scopus 로고    scopus 로고
    • Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development
    • DOI 10.1182/blood-2004-11-4467
    • Schlaeger TM, Mikkola HK, Gekas C et al. Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development. Blood 2005;105:3871-3874. (Pubitemid 40656130)
    • (2005) Blood , vol.105 , Issue.10 , pp. 3871-3874
    • Schlaeger, T.M.1    Mikkola, H.K.A.2    Gekas, C.3    Helgadottir, H.B.4    Orkin, S.H.5
  • 38
    • 22044432420 scopus 로고    scopus 로고
    • VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin
    • DOI 10.1182/blood-2004-09-3417
    • Ulyanova T, Scott LM, Priestley GV et al. VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin. Blood 2005;106:86-94. (Pubitemid 40967178)
    • (2005) Blood , vol.106 , Issue.1 , pp. 86-94
    • Ulyanova, T.1    Scott, L.M.2    Priestley, G.V.3    Jiang, Y.4    Nakamoto, B.5    Koni, P.A.6    Papayannopoulou, T.7
  • 40
    • 34247249338 scopus 로고    scopus 로고
    • Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development
    • DOI 10.1016/j.ydbio.2007.02.002, PII S0012160607000942
    • Lincoln J, Kist R, Scherer G et al. Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development. Dev Biol. 2007;305:120-132. (Pubitemid 46613795)
    • (2007) Developmental Biology , vol.305 , Issue.1 , pp. 120-132
    • Lincoln, J.1    Kist, R.2    Scherer, G.3    Yutzey, K.E.4
  • 41
    • 34948856826 scopus 로고    scopus 로고
    • Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
    • Srinivasan RS, Dillard ME, Lagutin OV et al. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev 2007;21:2422-2432.
    • (2007) Genes Dev , vol.21 , pp. 2422-2432
    • Srinivasan, R.S.1    Dillard, M.E.2    Lagutin, O.V.3
  • 43
    • 10344247125 scopus 로고    scopus 로고
    • Haemangioblast commitment is initiated in the primitive streak of the mouse embryo
    • DOI 10.1038/nature03122
    • Huber TL, Kouskoff V, Fehling HJ et al. Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature 2004;432:625-630. (Pubitemid 39626269)
    • (2004) Nature , vol.432 , Issue.7017 , pp. 625-630
    • Huber, T.L.1    Kouskoff, V.2    Fehling, H.J.3    Palis, J.4    Keller, G.5
  • 44
    • 44449152487 scopus 로고    scopus 로고
    • The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF
    • DOI 10.1242/dev.011767
    • Pearson S, Sroczynska P, Lacaud G et al. The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF. Development 2008;135:1525-1535. (Pubitemid 351753642)
    • (2008) Development , vol.135 , Issue.8 , pp. 1525-1535
    • Pearson, S.1    Sroczynska, P.2    Lacaud, G.3    Kouskoff, V.4
  • 45
    • 0031833476 scopus 로고    scopus 로고
    • + cells at a diverging point of endothelial and hemopoietic lineages
    • Nishikawa SI, Nishikawa S, Hirashima M et al. Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 1998;125:1747-1757. (Pubitemid 28256742)
    • (1998) Development , vol.125 , Issue.9 , pp. 1747-1757
    • Nishikawa, S.-I.1    Nishikawa, S.2    Hirashima, M.3    Matsuyoshi, N.4    Kodama, H.5
  • 46
    • 17744416048 scopus 로고    scopus 로고
    • In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos
    • Nishikawa SI, Nishikawa S, Kawamoto H et al. In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Immunity 1998;8:761-769.
    • (1998) Immunity , vol.8 , pp. 761-769
    • Nishikawa, S.I.1    Nishikawa, S.2    Kawamoto, H.3
  • 47
    • 40949152389 scopus 로고    scopus 로고
    • Multiple mesoderm subsets give rise to endothelial cells, whereas hematopoietic cells are differentiated only from a restricted subset in embryonic stem cell differentiation culture
    • Era T, Izumi N, Hayashi M et al. Multiple mesoderm subsets give rise to endothelial cells, whereas hematopoietic cells are differentiated only from a restricted subset in embryonic stem cell differentiation culture. Stem Cells 2008;26:401-411.
    • (2008) Stem Cells , vol.26 , pp. 401-411
    • Era, T.1    Izumi, N.2    Hayashi, M.3
  • 48
    • 27644497255 scopus 로고    scopus 로고
    • Three pathways to mature macrophages in the early mouse yolk sac
    • DOI 10.1182/blood-2005-02-0461
    • Bertrand JY, Jalil A, Klaine M et al. Three pathways to mature macrophages in the early mouse yolk sac. Blood 2005;106:3004-3011. (Pubitemid 41565892)
    • (2005) Blood , vol.106 , Issue.9 , pp. 3004-3011
    • Bertrand, J.Y.1    Jalil, A.2    Klaine, M.3    Jung, S.4    Cumano, A.5    Godin, I.6
  • 49
    • 0037438975 scopus 로고    scopus 로고
    • Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo
    • DOI 10.1182/blood-2002-06-1699
    • Mikkola HK, Fujiwara Y, Schlaeger TM et al. Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 2003;101:508-516. (Pubitemid 36082842)
    • (2003) Blood , vol.101 , Issue.2 , pp. 508-516
    • Mikkola, H.K.A.1    Fujiwara, Y.2    Schlaeger, T.M.3    Traver, D.4    Orkin, S.H.5
  • 52
    • 48649089713 scopus 로고    scopus 로고
    • Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin(+)CD45(+) pre-definitive HSCs
    • Taoudi S, Gonneau C, Moore K et al. Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin(+)CD45(+) pre-definitive HSCs. Cell Stem Cell. 2008;3:99-108.
    • (2008) Cell Stem Cell , vol.3 , pp. 99-108
    • Taoudi, S.1    Gonneau, C.2    Moore, K.3
  • 53
    • 33751510220 scopus 로고    scopus 로고
    • The allantois and chorion, when isolated before circulation or chorio-allantoic fusion, have hematopoietic potential
    • DOI 10.1242/dev.02596
    • Zeigler BM, Sugiyama D, Chen M et al. The allantois and chorion, when isolated before circulation or chorio-allantoic fusion, have hematopoietic potential. Development 2006;133:4183-4192. (Pubitemid 44830662)
    • (2006) Development , vol.133 , Issue.21 , pp. 4183-4192
    • Zeigler, B.M.1    Sugiyama, D.2    Chen, M.3    Guo, Y.4    Downs, K.M.5    Speck, N.A.6
  • 55
    • 50249087471 scopus 로고    scopus 로고
    • The discovery of a source of adult hematopoietic cells in the embryo
    • Dzierzak E, Medvinsky A. The discovery of a source of adult hematopoietic cells in the embryo. Development 2008;135:2343-2346.
    • (2008) Development , vol.135 , pp. 2343-2346
    • Dzierzak, E.1    Medvinsky, A.2
  • 57
    • 30144434921 scopus 로고    scopus 로고
    • Runx1 function in hematopoiesis is required in cells that express Tek
    • DOI 10.1182/blood-2005-05-1955
    • Li Z, Chen MJ, Stacy T et al. Runx1 function in hematopoiesis is required in cells that express Tek. Blood 2006;107:106-110. (Pubitemid 43053530)
    • (2006) Blood , vol.107 , Issue.1 , pp. 106-110
    • Li, Z.1    Chen, M.J.2    Stacy, T.3    Speck, N.A.4
  • 58
    • 31544466531 scopus 로고    scopus 로고
    • The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons
    • DOI 10.1038/nn1631, PII NN1631
    • Marmigère F, Montelius A, Wegner M et al. The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons. Nat Neurosci. 2006;9:180-187. (Pubitemid 43164540)
    • (2006) Nature Neuroscience , vol.9 , Issue.2 , pp. 180-187
    • Marmigere, F.1    Montelius, A.2    Wegner, M.3    Groner, Y.4    Reichardt, L.F.5    Ernfors, P.6
  • 61
    • 0036714991 scopus 로고    scopus 로고
    • Blood-forming potential of vascular endothelium in the human embryo
    • Oberlin E, Tavian M, Blazsek I et al. Blood-forming potential of vascular endothelium in the human embryo. Development 2002;129:4147-4157. (Pubitemid 35012499)
    • (2002) Development , vol.129 , Issue.17 , pp. 4147-4157
    • Oberlin, E.1    Tavian, M.2    Blazsek, I.3    Peault, B.4
  • 62
    • 0031696447 scopus 로고    scopus 로고
    • Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny
    • Jaffredo T, Gautier R, Eichmann A et al. Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development 1998;125:4575-4583. (Pubitemid 28564300)
    • (1998) Development , vol.125 , Issue.22 , pp. 4575-4583
    • Jaffredo, T.1    Gautier, R.2    Eichmann, A.3    Dieterlen-Lievre, F.4
  • 63
    • 56549101520 scopus 로고    scopus 로고
    • Fate tracing reveals the endothelial origin of hematopoietic stem cells
    • Zovein AC, Hofmann JJ, Lynch M et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell 2008;3:625-636.
    • (2008) Cell Stem Cell , vol.3 , pp. 625-636
    • Zovein, A.C.1    Hofmann, J.J.2    Lynch, M.3
  • 64
    • 60149100010 scopus 로고    scopus 로고
    • Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
    • Chen MJ, Yokomizo T, Zeigler BM et al. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature 2009.
    • (2009) Nature
    • Chen, M.J.1    Yokomizo, T.2    Zeigler, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.