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Volumn 7, Issue 8, 2009, Pages 1373-1383

Presence of platelet-associated anti-glycoprotein (GP)VI autoantibodies and restoration of GPVI expression in patients with GPVI deficiency

Author keywords

GPVI deficiency; Immune thrombocytopenic purpura; Platelet associated autoantibody

Indexed keywords

AUTOANTIBODY; COLLAGEN; FC RECEPTOR; GLYCOPROTEIN VI; GLYCOPROTEIN VI AUTOANTIBODY; IMMUNOGLOBULIN G; INTEGRIN; INTEGRIN ALPHA2B BETA3; UNCLASSIFIED DRUG;

EID: 68049111684     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03510.x     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 0038494921 scopus 로고    scopus 로고
    • Platelet-collagen interaction: Is GPVI the central receptor?
    • Nieswandt B, Watson SP. Platelet-collagen interaction: Is GPVI the central receptor? Blood 2003; 102: 449-61.
    • (2003) Blood , vol.102 , pp. 449-461
    • Nieswandt, B.1    Watson, S.P.2
  • 2
    • 4644262225 scopus 로고    scopus 로고
    • Platelet glycoprotein. VI: Its structure and function
    • Moroi M, Jung SM. Platelet glycoprotein. VI: Its structure and function. Thromb Res 2004; 114: 221-33.
    • (2004) Thromb Res , vol.114 , pp. 221-233
    • Moroi, M.1    Jung, S.M.2
  • 4
    • 0023185207 scopus 로고
    • A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia
    • Sugiyama T, Okuma M, Ushikubi F, Sensaki S, Kanaji K, Uchino H. A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia. Blood 1987; 69: 1712-20.
    • (1987) Blood , vol.69 , pp. 1712-1720
    • Sugiyama, T.1    Okuma, M.2    Ushikubi, F.3    Sensaki, S.4    Kanaji, K.5    Uchino, H.6
  • 5
    • 0024426540 scopus 로고
    • A patient with platelets deficient in glycoprotein. VI that lack both collagen-induced aggregation and adhesion
    • Moroi M, Jung SM, Okuma M, Shinmyozu K. A patient with platelets deficient in glycoprotein. VI that lack both collagen-induced aggregation and adhesion. J Clin Invest 1989; 84: 1440-5.
    • (1989) J Clin Invest , vol.84 , pp. 1440-1445
    • Moroi, M.1    Jung, S.M.2    Okuma, M.3    Shinmyozu, K.4
  • 6
    • 0026564824 scopus 로고
    • Deficiency of P62, a putative collagen receptor, in platelets from a patient with defective collagen-induced platelet aggregation
    • Ryo R, Yoshida A, Sugano W, Yasunaga M, Nakayama K, Saigo K, Adachi M, Yamaguchi N, Okuma M. Deficiency of P62, a putative collagen receptor, in platelets from a patient with defective collagen-induced platelet aggregation. Am J Hematol 1992; 39: 25-31.
    • (1992) Am J Hematol , vol.39 , pp. 25-31
    • Ryo, R.1    Yoshida, A.2    Sugano, W.3    Yasunaga, M.4    Nakayama, K.5    Saigo, K.6    Adachi, M.7    Yamaguchi, N.8    Okuma, M.9
  • 7
    • 0028928125 scopus 로고
    • Platelets with 10% of the normal amount of glycoprotein. VI have an impaired response to collagen that results in a mild bleeding tendency
    • Arai M, Yamamoto N, Moroi M, Akamatsu N, Fukutake K, Tanoue K. Platelets with 10% of the normal amount of glycoprotein. VI have an impaired response to collagen that results in a mild bleeding tendency. Br J Haematol 1995; 89: 124-30.
    • (1995) Br J Haematol , vol.89 , pp. 124-1230
    • Arai, M.1    Yamamoto, N.2    Moroi, M.3    Akamatsu, N.4    Fukutake, K.5    Tanoue, K.6
  • 8
    • 0034930596 scopus 로고    scopus 로고
    • Antibody against platelet membrane glycoprotein. VI in a patient with systemic lupus erythematosus
    • Takahashi H, Moroi M. Antibody against platelet membrane glycoprotein. VI in a patient with systemic lupus erythematosus. Am J Hematol 2001; 67: 262-7.
    • (2001) Am J Hematol , vol.67 , pp. 262-267
    • Takahashi, H.1    Moroi, M.2
  • 10
    • 4444244926 scopus 로고    scopus 로고
    • Anti-GPVI-associated ITP: An acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRγ-chain complex from the human platelet surface
    • Boylan B, Chen H, Rathore V, Paddock C, Salacz M, Friedman KD, Curtis BR, Stapleton M, Newman DK, Kahn ML, Newman PJ. Anti-GPVI-associated ITP: An acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRγ-chain complex from the human platelet surface. Blood 2004; 104: 1350-5.
    • (2004) Blood , vol.104 , pp. 1350-1355
    • Boylan, B.1    Chen, H.2    Rathore, V.3    Paddock, C.4    Salacz, M.5    Friedman, K.D.6    Curtis, B.R.7    Stapleton, M.8    Newman, D.K.9    Kahn, M.L.10    Newman, P.J.11
  • 11
    • 33750087249 scopus 로고    scopus 로고
    • Characterization of a patient with glycoprotein (GP). VI deficiency possessing neither anti-GPVI autoantibody nor genetic aberration
    • Kojima H, Moroi M, Jung SM, Goto S, Tamura N, Kozuma Y, Suzukawa K, Nagasawa T. Characterization of a patient with glycoprotein (GP). VI deficiency possessing neither anti-GPVI autoantibody nor genetic aberration. J Thromb Haemost 2006; 4: 2433-42.
    • (2006) J Thromb Haemost , vol.4 , pp. 2433-2442
    • Kojima, H.1    Moroi, M.2    Jung, S.M.3    Goto, S.4    Tamura, N.5    Kozuma, Y.6    Suzukawa, K.7    Nagasawa, T.8
  • 13
    • 68049085476 scopus 로고    scopus 로고
    • GPVI mutation and absent platelet collagen activation in a patient with a bleeding disorder
    • (abstract)
    • Freson K, Hermans C, Thys C, van Geet C. GPVI mutation and absent platelet collagen activation in a patient with a bleeding disorder. Blood 2007; 110: 627a (abstract).
    • (2007) Blood , vol.110
    • Freson, K.1    Hermans, C.2    Thys, C.3    van Geet, C.4
  • 14
    • 70350451132 scopus 로고    scopus 로고
    • Absent collagen-induced platelet activation in a patient double heterozygous for two GPVI mutations
    • (abstract)
    • Jandrot-Perrus M, Dumont B, Lasne D, Rothschild C, Grandchamp B, Ajzenberg N. Absent collagen-induced platelet activation in a patient double heterozygous for two GPVI mutations. Blood 2008; 112: 39 (abstract).
    • (2008) Blood , vol.112 , pp. 39
    • Jandrot-Perrus, M.1    Dumont, B.2    Lasne, D.3    Rothschild, C.4    Grandchamp, B.5    Ajzenberg, N.6
  • 15
    • 68049098987 scopus 로고    scopus 로고
    • Regulation of an acquired inhibitor to the GPVI platelet collagen receptor in a patient with an autoimmune syndrome and kidney disease
    • (abstract)
    • Nurden P, Tandon N, Takizawa H, Gong X, Conception A, Morel D, Merville P, Loya S, Jandrot-Perrus M, Nurden AT. Regulation of an acquired inhibitor to the GPVI platelet collagen receptor in a patient with an autoimmune syndrome and kidney disease. Blood 2008; 112: 1168 (abstract).
    • (2008) Blood , vol.112 , pp. 1168
    • Nurden, P.1    Tandon, N.2    Takizawa, H.3    Gong, X.4    Conception, A.5    Morel, D.6    Merville, P.7    Loya, S.8    Jandrot-Perrus, M.9    Nurden, A.T.10
  • 16
    • 34948848572 scopus 로고    scopus 로고
    • Platelet glycoprotein. VI-related clinical defects
    • Arthur JF, Dunkley S, Andrews RK. Platelet glycoprotein. VI-related clinical defects. Br J Haematol 2007; 139: 363-72.
    • (2007) Br J Haematol , vol.139 , pp. 363-372
    • Arthur, J.F.1    Dunkley, S.2    Andrews, R.K.3
  • 20
    • 33746590241 scopus 로고    scopus 로고
    • Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: Development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents
    • Boylan B, Berndt MC, Kahn ML, Newman PJ. Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents. Blood 2006; 108: 908-14.
    • (2006) Blood , vol.108 , pp. 908-914
    • Boylan, B.1    Berndt, M.C.2    Kahn, M.L.3    Newman, P.J.4
  • 22
    • 35649019167 scopus 로고    scopus 로고
    • Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane
    • Arthur JF, Shen Y, Kahn ML, Berndt MC, Andrews RK, Gardiner EE. Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. J Biol Chem 2007; 282: 30434-41.
    • (2007) J Biol Chem , vol.282 , pp. 30434-30441
    • Arthur, J.F.1    Shen, Y.2    Kahn, M.L.3    Berndt, M.C.4    Andrews, R.K.5    Gardiner, E.E.6
  • 23
    • 33747872565 scopus 로고    scopus 로고
    • Analyzing the mechanism of Rap1 activation in platelets: Rap1 activation is related to the release reaction mediated through the collagen receptor GPVI
    • Jung SM, Ohnuma M, Watanabe N, Sonoda M, Handa M, Moroi M. Analyzing the mechanism of Rap1 activation in platelets: Rap1 activation is related to the release reaction mediated through the collagen receptor GPVI. Thromb Res 2006; 118: 509-21.
    • (2006) Thromb Res , vol.118 , pp. 509-521
    • Jung, S.M.1    Ohnuma, M.2    Watanabe, N.3    Sonoda, M.4    Handa, M.5    Moroi, M.6
  • 24
    • 0032531105 scopus 로고    scopus 로고
    • A two-amino acid insertion in the Cys146-Cys167 loop of the αIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding
    • Honda S, Tomiyama Y, Shiraga M, Tadokoro S, Takamatsu J, Saito H, Kurata Y, Matsuzawa Y. A two-amino acid insertion in the Cys146-Cys167 loop of the αIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding. J Clin Invest 1998; 102: 1183-92.
    • (1998) J Clin Invest , vol.102 , pp. 1183-1192
    • Honda, S.1    Tomiyama, Y.2    Shiraga, M.3    Tadokoro, S.4    Takamatsu, J.5    Saito, H.6    Kurata, Y.7    Matsuzawa, Y.8
  • 26
    • 0035885952 scopus 로고    scopus 로고
    • Platelet-associated anti-GPIIb-IIIa autoantibodies in chronic immune thrombocytopenic purpura recognizing epitopes close to the ligand-binding site of glycoprotein (GP) IIb
    • Kosugi S, Tomiyama Y, Honda S, Kato H, Kiyoi T, Kashiwagi H, Kurata Y, Matsuzawa Y. Platelet-associated anti-GPIIb-IIIa autoantibodies in chronic immune thrombocytopenic purpura recognizing epitopes close to the ligand-binding site of glycoprotein (GP) IIb. Blood 2001; 98: 1819-27.
    • (2001) Blood , vol.98 , pp. 1819-1827
    • Kosugi, S.1    Tomiyama, Y.2    Honda, S.3    Kato, H.4    Kiyoi, T.5    Kashiwagi, H.6    Kurata, Y.7    Matsuzawa, Y.8
  • 28
    • 0027138150 scopus 로고
    • Elevated platelet-associated IgG in SLE patients due to anti-platelet autoantibody: Differentiation between autoantibodies and immune complexes by ether elution
    • Kurata Y, Hayashi S, Kosugi S, Kashiwagi H, Tomiyama Y, Kanayama Y, Matsuzawa Y. Elevated platelet-associated IgG in SLE patients due to anti-platelet autoantibody: Differentiation between autoantibodies and immune complexes by ether elution. Br J Haematol 1993; 85: 723-8.
    • (1993) Br J Haematol , vol.85 , pp. 723-728
    • Kurata, Y.1    Hayashi, S.2    Kosugi, S.3    Kashiwagi, H.4    Tomiyama, Y.5    Kanayama, Y.6    Matsuzawa, Y.7
  • 29
    • 0012954418 scopus 로고    scopus 로고
    • A naturally occurring Tyr143His αIIb mutation abolishes αIIbβ3 function for soluble ligands but retains its ability for mediating cell adhesion and clot retraction: Comparison with other mutations causing ligand-binding defects
    • Kiyoi T, Tomiyama Y, Honda S, Tadokoro S, Arai M, Kashiwagi H, Kosugi S, Kato H, Kurata Y, Matsuzawa Y. A naturally occurring Tyr143His αIIb mutation abolishes αIIbβ3 function for soluble ligands but retains its ability for mediating cell adhesion and clot retraction: Comparison with other mutations causing ligand-binding defects. Blood 2003; 101: 3485-91.
    • (2003) Blood , vol.101 , pp. 3485-3491
    • Kiyoi, T.1    Tomiyama, Y.2    Honda, S.3    Tadokoro, S.4    Arai, M.5    Kashiwagi, H.6    Kosugi, S.7    Kato, H.8    Kurata, Y.9    Matsuzawa, Y.10
  • 30
    • 0026593434 scopus 로고
    • Antivinculin antibodies in sera of patients with immune thrombocytopenia and in sera of normal subjects
    • Tomiyama Y, Kekomäki R, McFarland J, Kunicki TJ. Antivinculin antibodies in sera of patients with immune thrombocytopenia and in sera of normal subjects. Blood 1992; 79: 161-8.
    • (1992) Blood , vol.79 , pp. 161-168
    • Tomiyama, Y.1    Kekomäki, R.2    McFarland, J.3    Kunicki, T.J.4
  • 34
    • 0027247408 scopus 로고
    • The effect of therapy on platelet-associated autoantibody in chronic immune thrombocytopenic purpura
    • Fujisawa K, Tani P, Pilo L, McMillan R. The effect of therapy on platelet-associated autoantibody in chronic immune thrombocytopenic purpura. Blood 1993; 81: 2872-7.
    • (1993) Blood , vol.81 , pp. 2872-2877
    • Fujisawa, K.1    Tani, P.2    Pilo, L.3    McMillan, R.4
  • 36
    • 0344736747 scopus 로고    scopus 로고
    • Antiplatelet antibodies in chronic adult immune thrombocytopenic purpura: Assays and epitopes
    • McMillan R. Antiplatelet antibodies in chronic adult immune thrombocytopenic purpura: Assays and epitopes. J Pediatr Hematol Oncol 2003; 25 (Suppl. 1): S57-61.
    • (2003) J Pediatr Hematol Oncol , vol.25 , Issue.SUPPL. 1
    • McMillan, R.1
  • 37
    • 32044458448 scopus 로고    scopus 로고
    • Ex.vivo evaluation of anti-GPVI antibody in cynomolgus monkeys: Dissociation between anti-platelet aggregatory effect and bleeding time
    • Matsumoto Y, Takizawa H, Nakama K, Gong X, Yamada Y, Tandon NN, Kambayashi J. Ex vivo evaluation of anti-GPVI antibody in cynomolgus monkeys: Dissociation between anti-platelet aggregatory effect and bleeding time. Thromb Haemost 2006; 96: 167-75.
    • (2006) Thromb Haemost , vol.96 , pp. 167-175
    • Matsumoto, Y.1    Takizawa, H.2    Nakama, K.3    Gong, X.4    Yamada, Y.5    Tandon, N.N.6    Kambayashi, J.7
  • 39
    • 43749099001 scopus 로고    scopus 로고
    • Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression
    • Ohlmann P, Hechler B, Ravanat C, Loyau S, Herrenschmidt N, Wanert F, Jandrot-Perrus M, Gachet C. Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression. J Thromb Haemost 2008; 6: 1003-11.
    • (2008) J Thromb Haemost , vol.6 , pp. 1003-1011
    • Ohlmann, P.1    Hechler, B.2    Ravanat, C.3    Loyau, S.4    Herrenschmidt, N.5    Wanert, F.6    Jandrot-Perrus, M.7    Gachet, C.8


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