Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro

Experimental and Molecular Medicine

Volumn 41, Issue 7, 2009, Pages 508-516

  Yang, Le ^a   Zou, Xiao Jing ^a   Gao, Xiang ^a   Chen, Hao ^b   Luo, Jin Long ^a   Wang, Zhao Hua ^a   Liang, Qian Sheng ^a   Yang, Guang Tian ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Angiotensin II; Collagen; Fibrosis; Heart; Reactive oxygen species; Tanshinone

Indexed keywords

ACETYLCYSTEINE; ANGIOTENSIN II; COLLAGEN TYPE 1; INTERSTITIAL COLLAGENASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TANSHINONE IIA; TANSHINONE IIA SULFONIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; FIBROBLAST CULTURE; HEART MUSCLE FIBROSIS; IN VITRO STUDY; NONHUMAN; PROTEIN EXPRESSION;

EID: 68049097297     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.7.056     Document Type: Article

References (44)

1. Ashizawa N, Graf K, Do YS, Nunohiro T, Giachelli CM, Meehan WP, Tuan TL, Hsueh WA. Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)-induced DNA synthesis and collagen gel contraction. J Clin Invest 1996;98:2218-2227 (Pubitemid 26394194)
2. Brilla CG, Zhou G, Matsubara L, Weber KT. Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone. J Mol Cell Cardiol 1994;26:809-820 (Pubitemid 24223231)
3. Brown L. Cardiac extracellular matrix: a dynamic entity. Am J Physiol Heart Circ Physiol 2005;289:973-974 (Pubitemid 41208934)
4. Brown RD, Jones GM, Laird RE, Hudson P, Long CS. Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblasts. Biochem Biophys Res Commun 2007;362:200-205 (Pubitemid 47304407)
5. Chen J, Mehta JL. Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone. Am J Physiol Heart Circ Physiol 2006;291:1738-1745 (Pubitemid 44497679)
6. Chen K, Chen J, Li D, Zhang X, Mehta JL. Angiotensin II regulation of collagen type I expression in cardiac fibroblasts: modulation by PPAR-gamma ligand pioglitazone. Hypertension 2004a;44:655-661 (Pubitemid 39435235)
7. Chen K, Li D, Zhang X, Hermonat PL, Mehta JL. Anoxiareoxygenation stimulates collagen type-I and MMP-1 expression in cardiac fibroblasts: modulation by the PPAR-gamma ligand pioglitazone. J Cardiovasc Pharmacol 2004b;44:682-687 (Pubitemid 39587430)
8. Chen K, Mehta JL, Li D, Joseph L, Joseph J. Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II. Circ Res 2004c;95:1167-1173
9. Chen W, Dong Y, Wang C, Ting G. Pharmacological studies of sodium tanshinone IIA sulfonate. Acta Pharmacol Sin 1979;14:277-283
10. Cohn JN, Ferrari R, Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf on an international forum on cardiac remodelling. J Am Coll Cardiol 2000;35:569-582
11. D'Armiento J. Matrix metalloproteinase disruption of the extracellular matrix and cardiac dysfunction. Trends Cardiovasc Med 2002;12:97-101 (Pubitemid 34462178)
12. Fedak PW, Verma S, Weisel RD, Li RK. Cardiac remodeling and failure: From molecules to man (Part II). Cardiovasc Pathol 2005;14:49-60 (Pubitemid 40381300)
13. Gibbons GH. The pathophysiology of hypertension: the importance of angiotensin II in cardiovascular remodeling. Am J Hypertens 1998;11:177-181
14. Heeneman S, Cleutjens JP, Faber BC, Creemers EE, van Suylen RJ, Lutgens E, Cleutjens KB, Daemen MJ. The dynamic extracellular matrix: intervention strategies during heart failure and atherosclerosis. J Pathol 2003;200:516-525 (Pubitemid 36818252)
15. Jaana Rysä, Hanna Leskinen, Mika Ilves, Heikki Ruskoaho. Distinct upregulation of extracellular matrix genes in transition from hypertrophy to hypertensive heart failure. Hypertension 2005;45:927-933
16. Kang BY, Chung SW, Kim SH, Ryu SY, Kim TS. Inhibition of interleukin-12 and interferon-gamma production in immune cells by tanshinones from Salvia miltiorrhiza. Immunopharmacology. 2000;49:355-361
17. Kass DA, Bronzwaer JG, Paulus WJ. What mechanisms underlie diastolic dysfunction in heart failure? Circ Res 2004;94:1533-1542
18. Kawano H, Do YS, Kawano Y, Starnes V, Barr M, Law RE. Angiotensin II has multiple profibrotic effects in human cardiac fibroblasts. Circulation 2000;101:1130-1137 (Pubitemid 30146614)
19. Kim S, Ohta K, Hamaguchi A, Yukimura T, Miura K, Iwao H. Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats. Hypertension. 1995;25:1252-1259
20. Kumar R, Singh VP, Baker KM. The intracellular reninangiotensin system: implications in cardiovascular remodeling. Curr Opin Nephrol Hypertens 2008;17:168-173 (Pubitemid 351253042)
21. Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 2004;4:181-189
22. Lijnen P, Papparella I, Petrov V, Semplicini A, Fagard R. Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species. J Hypertens 2006;24:757-766
23. Lijnen PJ, Petrov VV, Fagard RH. Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors. J Renin Angiotensin Aldosterone Syst 2001;2:117-122
24. Murdoch CE, Grieve DJ, Cave AC, Looi YH, Shah AM. NADPH oxidase and heart failure. Curr Opin Pharmacol 2006;6:148-153
25. Pan CH, Wen CH, Lin CS. Interplay of angiotensin II and angiotensin(1-7) in the regulation of matrix metalloproteinases of human cardiocytes. Exp Physiol 2008;93:599-612
26. Rouet-Benzineb P, Gontero B, Dreyfus P, Lafuma C. Angiotensin II induces nuclear factor-kappa B activation in cultured neonatal rat cardiomyocytes through protein kinase C signaling pathway. J Mol Cell Cardiol 2000;32:1767-1778 (Pubitemid 30809625)
27. Seeger H, Lippert C, Wallwiener D, Mueck AO. Valsartan and candesartan can inhibit deteriorating effects of angiotensin II on coronary endothelial function. J Renin Angiotensin Aldosterone Syst 2001;2:141-143 (Pubitemid 33686754)
28. Su CC, Lin YH. Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-alpha in colon cancer cells in vitro and in vivo. Int J Mol Med. 2008;22:847-851
29. Sun Y, Weber KT. RAS and connective tissue in the heart. Int J Biochem Cell Biol 2003;35:919-931
30. Takahashi K, Ouyang X, Komatsu K, Nakamura N, Hattori M, Baba A, Azuma J. Sodium tanshinone IIA sulfonate derived from Danshen (Salvia miltiorrhiza) attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac cells. Biochem Pharmacol 2002;64:745-749 (Pubitemid 34886473)
31. Tang W, Eisenbrand G. Salvia miltiorrhiza Bge. Chinese drugs of plant origin, 1992, 891-902, Springer, Berlin, Germany.
32. Wang XW, Wu L, Miao MS, Zhu D, Xing YL, Ma YJ, Zhong ZY, Zhou Z, Wang SQ. WITHDRAWN: Tanshinone IIA protects rat cardiomyocytes against apoptosis induced by angiotensin II in vitro. Eur J Pharmacol 2008 Jul 17. (Epub ahead of print).
33. Weber KT, Brilla CG. Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 1991;83:1849-1865
34. Weber KT, Sun Y, Tyagi SC, Cleutjens JP. Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol 1994;26:279-292 (Pubitemid 24199288)
35. Weber KT, Sun Y, Katwa LC, Cleutjens JP. Connective tissue: a metabolic entity? J Mol Cell Cardiol 1995;27:107-120
36. Wood DA. Preventing clinical heart failure: the rationale and scientific evidence. Heart 2002;88:15-22
37. Yang L, Zou X, Liang Q, Chen H, Feng J, Yan L, Wang Z, Zhou D, Li S, Yao S, Zheng Z. Sodium tanshinone IIA sulfonate depresses angiotensin II-induced cardiomyocyte hypertrophy through MEK/ERK pathway. Exp Mol Med 2007;39:65-73 (Pubitemid 46356007)
38. Yang R, Liu A, Ma X, Li L, Su D, Liu J. Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation. J Cardiovasc Pharmacol 2008;51:396-401 (Pubitemid 351572239)
39. Zhang H, Pi R, Li R, Wang P, Tang F, Zhou S, Gao J, Jiang J, Chen S, Liu P. PPARbeta/delta activation inhibits angiotensin II-induced collagen type I expression in rat cardiac fibroblasts. Arch Biochem Biophys 2007;460:25-32 (Pubitemid 46482426)
40. Zhao BL, Jiang W, Zhao Y, Hou JW, Xin WJ. Scavenging effects of salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury. Biochem Mol Biol Int 1996;38:1171-1182 (Pubitemid 26334731)
41. Zhou G, Jiang W, Zhao Y, Ma G, Xin W, Yin J, Zhao B. Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria. Biochem Pharmacol 2003;65:51-57 (Pubitemid 35447838)
42. Zhou GY, Zhao BL, Hou JW, Ma GE, Xin WJ. Protective effects of sodium tanshinone IIA sulphonate against adriamycin-induced lipid peroxidation in mice hearts in vivo and in vitro. Pharmacol Res 1999;40:487-491
43. Zhou L, Shao Y, Huang Y, Yao T, Lu LM. 17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors. Eur J Pharmacol 2007;567:186-192 (Pubitemid 46976891)
44. Zhou L, Chan WK, Xu N, Xiao K, Luo H, Luo KQ, Chang DC. Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest. Life Sci. 2008;83:394-403